方仁東，男，博士，西南大學動物科技學院副教授，研究生導師。
基本介紹
- 中文名：方仁東
- 性別：男
- 職稱：副教授
- 學歷：博士
*學習工作經歷:
2014/04-至今，西南大學動物科技學院，副教授，研究生導師。
2009/10-2014/03 京都大學(日本)，基礎醫學院微生物學專業，博士；
2008/09-2009/08 東北師範大學，中國赴日本國留學生預備學校，日語二級；
2006/08-2008/04 復旦大學，教育部醫學分子病毒學重點實驗室，客座研究；
2005/09-2008/07 西南大學，預防獸醫學，碩士；
2000/09-2005/07 西南大學，動物科技學院動物醫學專業，本科。
*研究生招生專業及方向:
090602預防獸醫學
-03動物檢疫及動物性產品質量監測
主要學術論文：
發表學術論文10餘篇, 代表性論文在《自然-免疫學》，《免疫學雜誌》，《感染與免疫》，《臨床微生物學雜誌》 （Nature Immunology，Journal of Immunology，Infection and Immunity, Journal of Clinical Microbiology）等SCI雜誌發表。
1. Hideki Hara, Kohsuke Tsuchiya, Ikuo Kawamura, Rendong Fang, Hernandez-Cuellar E, Masao Mitsuyama et al. Syk- and JNK-mediated ASC phosphorylation acts as a molecular switch controlling the formation of speck-like aggregates upon inflammasome activation. Nature Immunology. 2013, 14(12):1247-1255. (IF=26.2, Cited: 19 until Nov. 2014)
2. Rendong Fang, Hideki Hara, Kohsuke Tsuchiya et al. Type I interferon singnaling regulates the activation of the absent in melanoma 2 inflammasome during Streptococcus pneumoniae infection. Infection and Immunity. 2014 Jun;82(6):2310-7. (IF=4.07)
3. Rendong Fang, Kohsuke Tsuchiya, Ikuo Kawamura, et al. Critical Roles of ASC Inflammasomes in Caspase-1 Activation and Host Innate Resistance to Streptococcus pneumoniae Infection. Journal of Immunology. 2011 Nov 1;187(9):4890-9 (IF=5.52, Cited: 39 until Nov. 2014)
4. Rendong Fang, Xia Li, Qian Gao, et al. Cross-Priming Amplification for Rapid Diagnosis of Mycobacterium tuberculosis in Sputum Specimens. Journal of Clinical Microbiology. 2009 Mar; 47(3):845–847. (IF=4.07, Cited: 45 until Nov. 2014)
5. Rendong Fang, Xia Li, Jing Li, Jie Wu, Xin Shen, Xiaohong Gui, Kathryn DeRiemer, Li Liu, Jian Mei, Qian Gao, Mixed Infections of Mycobacterium tuberculosis in Tuberculosis Patients in Shanghai, China. Tuberculosis. 2008 Sep;88(5):469-73. (IF=2.61, Cited: 16 until Nov. 2014)
6. Tsuchiya K, Hara H, Rendong Fang, Hernandez-Cuellar E, Sakai S, Daim S, Chen X, Dewamitta SR, Qu H, Mitsuyama M, Kawamura I. The adaptor ASC exacerbates lethal Listeria monocytogenes infection by mediating IL-18 production in an inflammasome-dependent and -independent manner. Eur J Immunol. 2014 Sep 23. [Epub ahead of print]
7. Hernandez-Cuellar E, Tsuchiya K, Hara H, Rendong Fang, Sakai S, Kawamura I, Akira S, Mitsuyama M. Nitric Oxide Inhibits the NLRP3 Inflammasome. Journal of Immunology. 2012 Dec 1;189(11):5113-7. (IF=5.52, Cited: 29 until Nov. 2014)
8. Takeshi Yamamoto, Hideki Hara, Kohsuke Tsuchiya, Sakai Shunsuke, Rendong Fang, Masao Mitsuyama et al. Listeria monocytogenes Strain-specific Impairment of the TetR Regulator Underlies the Drastic Increase in Cyclic di-AMP Secretion and Interferon β-Inducing Ability. Infection and Immunity. 2012 Apr 16. Epub ahead of print. (IF=4.07, Cited: 14 until Nov. 2014)
9. Tsuchiya K, Hara H, Kawamura I, Nomura T, Yamamoto T, Daim S, Dewamitta SR, Yannan Shen , Rendong Fang, Mitsuyama M. Involvement of absent in melanoma 2 in inflammasome activation in macrophages infected with Listeria monocytogenes. Journal of Immunology. 2010 Jul 15;185(2):1186-95. (IF=5.52, Cited: 64 until Nov. 2014)
10. Yang R, Xi C, Sita DR, Sakai S, Tsuchiya K, Hara H, Shen Y, Qu H, Rendong Fang, Mitsuyama M, Kawamura I. The RD1 locus in the Mycobacterium tuberculosis genome contributes to the maturation and secretion of IL-1α from infected macrophages through the elevation of cytoplasmic calcium levels and calpain activation. Pathogens and Disease. 2014 Feb;70(1):51-60.
