《文昌魚免疫系統(英文版)》是一本關於文昌魚免疫學研究的專著。文昌魚屬於脊索動物門頭索動物亞門，是現存與脊椎動物親緣最近的無脊椎動物之一，
基本介紹
- 書名：文昌魚免疫系統
- 作者：徐安龍
- ISBN：9787030323163
- 頁數：303
- 定價：148.00元
- 出版時間：2011-10
內容簡介,目錄,
內容簡介
《文昌魚免疫系統(英文版)》是一本關於文昌魚免疫學研究的專著。文昌魚屬於脊索動物門頭索動物亞門，是現存與脊椎動物親緣最近的無脊椎動物之一，被譽為研究脊椎動物起源和演化的“活化石”，也是研究脊椎動物免疫起源與演化，特別是由天然免疫到適應性免疫的過渡的最重要的模式生物。《文昌魚免疫系統(英文版)》詳細介紹了文昌魚研究歷史和文昌魚生物學，重點從比較免疫學的視角全面介紹了文昌魚免疫系統的研究進展，主要包括以文昌魚為代表的頭索動物天然免疫及其向脊椎動物的演化，頭索動物原始適應性免疫的基本框架。《文昌魚免疫系統(英文版)》同時向讀者介紹了近年文昌魚研究的一系列重大發現：如發現頭索動物免疫大爆炸現象，文昌魚中發現適應性免疫的標誌細胞——淋巴樣細胞及其信號轉導的關鍵分子，在頭索動物文昌魚中存在外源性細胞凋亡通路等。另外，《文昌魚免疫系統(英文版)》也分析了未來文昌魚免疫研究的發展方向。
目錄
About the Author
Foreword
Preface
1 Amphioxus is a model for understanding the evolution of vertebrate
1.1 Brief introduction ofamphioxus
1.2 Biology of amphioxus
1.2.1 Reproduction and embryogenesis of amphioxus
1.2.2 Anatomy of amphioxus
1.3 The Story ofamphioxus and its early researches in China
References
2 Basic knowledge of immunology
2.1 Immune organs
2.1.1 Primary lymphoid organs
2.1.2 Secondary lymphoid organs
2.2 Immune cells
2.2.1 Lymphoid cells
2.2.2 Innate immunity associated cells
2.3 Innate immunity
2.3.1 Toll-like receptors involved signaling pathway
2.3.2 Nod-like receptors and their functions
2.3.3 RIG-like receptors
2.3.4 C-type lectins
2.3.5 The scavenger receptors
2.3.6 Inflammation
2.4 Adaptive immunity
2.4.1 Specificity
2.4.2 Diversity
2.4.3 Immunological memory
2.4.4 Selfononself recognition
2.5 Complement system
2.5.1 Complement pathways
2.5.2 Complement in host defense
References
3 Immune organs and cells of amphioxus
3.1 Introduction
3.2 Organs of the amphioxus immune system
3.2.1 Amphioxus gill slits: the first immune defense line
3.2.2 Amphioxus intestine: not just a digestive organ but also an immune organ
3.3 Cells of the amphioxus immune system
3.3.1 Phagocytes
3.3.2 Lymphocyte-like cells
References
Genomic and transeriptomic view of the amphioxus immunity.
4.1 Introduction
4.2 Trace evidence of adaptive immunity
4.2.1 TCRs, Igs and VLRs
4.2.2 MHC and genes involved in antigen presentation
4.3 Extraordinary gene expansion in the amphioxus innate immunity..
4.3.1 The TLR system
4.3.2 TheNLR system
4.3.3 LRRIG proteins
4.3.4 Other LRR-containing genes
4.3.5 C-type lectins
4.3.6 Scavenger receptors
4.3.7 RIG-I-like helicases
4.3.8 Complement-related receptors
4.3.9 The TNF system
4.3.10 Expansion and reshuffling of the death-fold domains
4.3.1l Expansion of TIR adaptors, TRAFs and initiator caspases
Abbreviation Index
Key Words Index
Foreword
Preface
1 Amphioxus is a model for understanding the evolution of vertebrate
1.1 Brief introduction ofamphioxus
1.2 Biology of amphioxus
1.2.1 Reproduction and embryogenesis of amphioxus
1.2.2 Anatomy of amphioxus
1.3 The Story ofamphioxus and its early researches in China
References
2 Basic knowledge of immunology
2.1 Immune organs
2.1.1 Primary lymphoid organs
2.1.2 Secondary lymphoid organs
2.2 Immune cells
2.2.1 Lymphoid cells
2.2.2 Innate immunity associated cells
2.3 Innate immunity
2.3.1 Toll-like receptors involved signaling pathway
2.3.2 Nod-like receptors and their functions
2.3.3 RIG-like receptors
2.3.4 C-type lectins
2.3.5 The scavenger receptors
2.3.6 Inflammation
2.4 Adaptive immunity
2.4.1 Specificity
2.4.2 Diversity
2.4.3 Immunological memory
2.4.4 Selfononself recognition
2.5 Complement system
2.5.1 Complement pathways
2.5.2 Complement in host defense
References
3 Immune organs and cells of amphioxus
3.1 Introduction
3.2 Organs of the amphioxus immune system
3.2.1 Amphioxus gill slits: the first immune defense line
3.2.2 Amphioxus intestine: not just a digestive organ but also an immune organ
3.3 Cells of the amphioxus immune system
3.3.1 Phagocytes
3.3.2 Lymphocyte-like cells
References
Genomic and transeriptomic view of the amphioxus immunity.
4.1 Introduction
4.2 Trace evidence of adaptive immunity
4.2.1 TCRs, Igs and VLRs
4.2.2 MHC and genes involved in antigen presentation
4.3 Extraordinary gene expansion in the amphioxus innate immunity..
4.3.1 The TLR system
4.3.2 TheNLR system
4.3.3 LRRIG proteins
4.3.4 Other LRR-containing genes
4.3.5 C-type lectins
4.3.6 Scavenger receptors
4.3.7 RIG-I-like helicases
4.3.8 Complement-related receptors
4.3.9 The TNF system
4.3.10 Expansion and reshuffling of the death-fold domains
4.3.1l Expansion of TIR adaptors, TRAFs and initiator caspases
Abbreviation Index
Key Words Index
