扈洪波，男，中國農業大學食品科學與營養工程學院教授。
主要研究方向：營養/食物因素對癌症形成的調控作用及其分子機制；程式性細胞死亡(apoptosis, autophagy, necroptosis, paraptosis)的調控機制研究；食品中內分泌干擾物質檢測, 內分泌干擾毒性評價及毒理學機制。
研究方向,發表論文,
研究方向
1． 營養/食物因素對癌症形成的堡晚樂調控作用及其分子機制
2. 程式性細胞死亡(apoptosis, autophagy, necroptosis, paraptosis)的笑刪欠調控騙拒拔辯機制研究
3. 食品閥拘坑立中內分泌干擾物質檢測, 內分泌宙連干擾毒性評價糊剃剃及毒理學機制諒殼妹
發表論文
1） Hongbo Hu, Yubo Chai, Lei Wang, Jinhui Zhang, Hyo Jeong Lee, Sung-Hoon Kim, and Junxuan Lü Pentagalloylglucose induces autophagy and caspase-independent programmed deaths in human PC-3 and mouse TRAMP-C2 prostate cancer cells. Mol Cancer Ther October 2009 8:2833-2843
2） Hongbo Hu, Jinhui Zhang, Hyo Jeong Lee, Sung-Hoon Kim, Junxuan Lü Penta-O-galloyl-beta-D-glucose induces S- and G1-cell cycle arrests in prostate cancer cells targeting DNA replication and cyclin D1. Carcinogenesis 2009； 30(5):818-23
3） Hongbo Hu, Hyo-Jeong Lee, Cheng Jiang, Jinhui Zhang, Lei Wang, Yan Zhao, Qiu Xiang, Sung-Hoon Kim and Junxuan Lu. Penta-1,2,3,4,6-O-galloyl-beta-D- glucose induces p53 and inhibits STAT3 in prostate cancer cells in vitro and suppresses prostate xenograft tumor growth in vivo. Mol Cancer Ther. 2008 Sep;7(9):2681-91
4） Hongbo Hu, Guang-Xun Li, Lei Wang, Jenifer Watts, Gerald F Combs and Junxuan Lü. Methylseleninic acid enhances taxane drug efficacy against human prostate cancer and down regulates anti-apoptotic proteins Bcl-XL and survivin. Clinical Cancer Research. 2008;14,1150-1158
5） Hongbo Hu, Cheng Jiang, Todd Schuster, Guang-Xun Li, Peter T. Daniel and Junxuan Lü. Inorganic selenium sensitizes prostate cancer cells to TRAIL-induced apoptosis through superoxidep53Bax-mediated activation of mitochondrial pathway. Mol Cancer Ther. 2006;5:1873-82. (Selected for oral presentation at the 2006 AACR Annual Meeting in Washington, DC).
5） Hongbo Hu, Cheng Jiang, Todd Schuster, Guang-Xun Li, Peter T. Daniel and Junxuan Lü. Inorganic selenium sensitizes prostate cancer cells to TRAIL-induced apoptosis through superoxidep53Bax-mediated activation of mitochondrial pathway. Mol Cancer Ther. 2006;5:1873-82. (Selected for oral presentation at the 2006 AACR Annual Meeting in Washington, DC).
