徐文暉,男,博士,教授,博士生導師。1999年畢業於西北大學化學系,2010年獲得美國國家天然產物研究中心和西北農林科技大學聯合培養博士學位。目前在西南林業大學從事抗腫瘤,抗感染天然藥物及綠色高效生物農藥的研究與教學工作,主要圍繞新穎結構天然產物的發現,複雜天然產物的結構表征、生物功能與作用機理等開展研究。先後主持國家自然科學基金4項,以第一作者或通訊作者在J. Nat. Prod., Bioorg. Med. Chem., J. Ethnopharmacol., Fitoterapia,《中草藥》,《中國藥學雜誌》等國內外學術期刊發表研究論文40餘篇。並承擔研究生《植物活性成分分離原理與方法》、《有機結構分析》和本科生《藥用植物資源開發利用》等課程講授。現為國家自然科學基金評審專家,並擔任Current Medicinal Chemistry, Fitoterapia, Tetrahedron 等國際學術期刊審稿人。
基本介紹
主要科研項目,代表論文,
主要科研項目
雲南楝科植物中新型殺蟲活性檸檬苦素的快速定向挖掘及作用機制研究 國家自然科學基金 32.00萬元 主持
巴豆屬植物中殺煙蚜二萜先導結構發現和殺蚜活性及初步作用機理研究 國家自然科學基金 39.00萬元 主持
三種雲南特有胡椒屬植物的化學成分及抗深部真菌研究 國家自然科學基金 50.00萬元 主持
滇產三種大戟屬植物中新二萜結構發現及抗深部真菌研究 國家自然科學基金 47.00萬元 主持
代表論文
1. Liang Qian, Hu Jia-Xin, Zhang Xin-Min, Xu Wen-Hui*; Traditional uses, phytochemistry, pharmacology, toxicology, and quality control of Rhododendron dauricum L. leaves: A comprehensive review[J]. Journal of Ethnopharmacology, 2023, 305:116085.
2. Jia Rong-Lin, Liang Qian, Hu Jia-Xin, Xie Si-Da, Su Xiao-Min, Xu Wen-Hui*; Tigliane diterpenoids with cytotoxic activities from Croton damayeshu[J]. Phytochemistry Letters, 2023, 57: 110-114.
3. Su Xiao-Min, Liang Qian, Hu Jia-Xin, Zhang Xin-Min, Jia Rong-Lin, Xu Wen-Hui*; Diterpenoids from the whole plants of Croton yunnanensis and their bioactivities[J]. Bioorganic & Medicinal Chemistry, 2021, 51:116495.
4. Xu Wen-Hui*, Liang Zong-Suo, Su Xiao-Min, He Run-Xi, Liang Qian; Genus Picrasma: A comprehensive review on its ethnopharmacology, phytochemistry and bioactivities[J]. Journal of Ethnopharmacology, 2021, 280:114441.
5. Su Xiao-Min, Liang Qian, Zhang Xin-Min, Wang Meng, Wang Jing, Wen Zhen-Wei, Liu Fen, Nie Ting, Xu Jiao, Liu Rui, Xu Wen-Hui*; Phytochemical and chemotaxonomic study on Piper pleiocarpum Chang ex Tseng[J]. Biochemical Systematics and Ecology, 2021, 94:104187.
6. Su Xiao-Min, Liang Qian, Zhang Xin-Min, Yao Zeng-Yu, Xu Wen-Hui*; Four new chemical constituents from Piper pleiocarpum, Fitoterapia, 2020, 143:104544.
7. Xu Wen-Hui, Su Xiao-Min, Zhang Xin-Min, Qi JianHua, Wang Dawei, Wang Meng, Liang Qian*; Pleiocarpumlignan A, a new dineolignan from Piper pleiocarpum Chang ex Tseng. Natural Product Research, 2020, 34(19):2809-2815.
8. Xu Wen-Hui, Su Xiao-Min, Wang Chao, Du Fan, Liang Qian*; The genus Amoora: A phytochemical and pharmacological review [J]. Fitoterapia, 2019(137): 104269.
9. Liu Tie, Liang Qian, Zhang Xin-Min, Su Xiao-Min, Qin Jian-Chun, Li Gen-Qian, Xu Wen-Hui*;Chemical constituents from Euphorbia stracheyi Boiss [J]. Biochemical Systematics and Ecology, 2019, 84(6): 52-54.
10. Xu Wen-Hui, Zhao Ping, Wang Meng, Liang Qian; Naturally occurring furofuran lignans: structural diversity and biological activities [J]. Natural Product Research, 2019, 33(9):1357-1373.
11. Xu Wen-Hui, Liu Wei-Yi, Liang Qian; Chemical Constituents from Croton Species and Their Biological Activities [J]. Molecules, 2018, 23(9), 2333:1-38
12. Liu Tie, Liang Qian, Zhang Xin-Min, Huang Shen-Yang, Xu Wen-Hui*;A new furofuran lignan from Piper terminaliflorum Tseng [J]. Natural Product Research, 2018, 32(3): 335-340.
13. Liu Tie, Liang Qian, Zhang Xin-Min, Li Gen-Qian, Xu Bo, Xu Wen-Hui*;Chemical constituents from Piper boehmeriifolium (Miq.) Wall ex C. DC [J]. Biochemical Systematics and Ecology, 2017,75: 27-30.
14. Liu Tie, Liang Qian, Xiong Na-Na, Dai Lin-Feng, Wang Jun-Ming, Ji Xiao-Hui,Xu Wen-Hui*; A new ent-kaurane diterpene from Euphorbia stracheyi Boiss [J]; Natural Product Research, 2017, 31(2):233-238.
15. Dai Lin-Feng, Liang Qian, Liu Tie, He Ming-Yu, Zhao Ping, Xu Wen-Hui*;A new tigliane-type diterpene from Euphorbia dracunculoides Lam[J]. Natural Product Research, 2016, 30(14):1639–1645.
16. Xu Wen-Hui, Al-Rehaily Adnan J, Yousafa Muhammad, S. Ahmada Mohammad, I. Khan Shabana, A. Khana Ikhlas, Two New Flavonoids from Retama raetam [J]. Helvetica Chimica Acta, 2015, 98, (4): 561-568.
17. Xu Wen-Hui, Shen Yun-Heng, Liang Qian, Zhao Ping; New coumarin derivative from Euphorbia wallichii [J]. Natural Product Research, 2015, (29), 19: 1860–1864.
18. Xu Wen-Hui, Liang Qian , Zhang Ying-Jun, Zhao Ping;Naturally Occurring Arbutin Derivatives and Their Bioactivities [J]. Chemistry and Biodiversity, 2015, 12, (1): 54-81.
19. Liang Qian, Liu Jiang Hua, Xu Wen-Hui*; Chemical composition of essential oil from Ligularia dictyoneura [J], Chemistry of Natural Compounds, 2013, 49, (3): 555-556.
20. Liang Qian, Li Geng Qian, Xu Wen-Hui*; Chemical composition of essential oil from Hydrangea macrophylla flower [J], Chemistry of Natural Compounds, 2013, 49, (2): 365-366.
21. Xu Wen-Hui, Li Xing-Cong; Antifungal Compounds from Piper Species [J]. Current Bioactive Compounds, 2011.7 (4): 262-267.
22. Xu Wen-Hui, Liang Qian, Liang Zong-Suo, Li Xing-Cong. Two new eudesmane derivatives from Verbesina virginica[J]. Chinese Chemical Letters, 2010, 21, (6): 693-695.
23. Xu Wen-Hui, Jacob R. Melissa, Agarwal K. Ameeta, Clark M. Alice, Li Xing-Cong. Flavonol Glycosides from the American Native Plant Gaura longiflora [J]. Heterocycles, 2009, 78, (10): 2541-2548.
24. Xu Wen-Hui, Jacob R. Melissa, Agarwal K. Ameeta, Clark M. Alice, Li Xing-Cong. ent-Kaurane Glycosides from Tricalysia okelensis [J]. Chemical & Pharmaceutical Bulletin, 2010, 58, (2): 261-264.
25. Xu Wen-Hui, Ding yuan-qing, Jacob R. Melissa, Agarwal K. Ameeta, Clark M. Alice, Ferreira Daneel, Liang Zong-Suo, Li Xing-Cong. Puupehanol, a Sesquiterpene Dihydroquinone Derivative from the Marine Sponge Hyrtios sp. [J]. Bioorganic and Medicinal Chemistry Letters, 2009, 19, (21): 6140-6143.
26. Xu Wen-Hui, Jacob R. Melissa, Agarwal K. Ameeta, Clark M. Alice, Liang Zong-Suo, Li Xing-Cong. Verbesinosides A-F, 15, 27-Cyclooleanane Saponins from the American Native Plant Verbesina virginica [J]. Journal of Natural Products, 2009, 72, (6): 1022-1027.