基本介紹
- 中文名：徐在言
- 學位/學歷：博士
- 職業：教師
- 專業方向：動物肌肉生長發育以及肌纖維類型轉化分子調控機制等
- 任職院校：華中農業大學動物科學技術學院動物醫學院
個人經歷,研究方向,學術成果,榮譽獎項,
個人經歷
教育經歷
1996.09 - 2000.07， 青島農業大學，動物科學專業畢業，農學學士
2001.09 - 2004.06， 南昌大學，動物學，理學碩士
2004.09 - 2007.07，中國科學院水生生物研究所，水生生物學，理學博士
工作經歷
2007.07-2010.12，華中農業大學講師
2011.01至今，華中農業大學副教授、碩士生導師
2013..09-2014.12，美國喬治亞大學，訪問學者
研究方向
動物肌肉生長發育以及肌纖維類型轉化分子調控機制等
學術成果
1. Guo X,Li F,Xu Z,Yin A,Yin H,Li C,Chen SY. DOCK2 deficiency mitigates HFD-induced obesity by reducing adipose tissue inflammation and increasing energy expenditure. J Lipid Res,2017, 58(9): 1777-1784.
2. Wang X,Zeng R,Xu H,Xu Z*,Zuo B*. The nuclear protein-coding gene ANKRD23 negatively regulates myoblast differentiation.Gene, 2017, 629: 68-75.
3. Guo Y, Wang J, Zhu M, Zeng R, Xu Z, Li G, Zuo B*. Identification of MyoD-responsive transcripts reveals a novel long non-coding RNA (lncRNA-AK143003) that negatively regulates myoblast differentiation. Sci Rep, 2017, 7(1): 2828.
4. Zhang Y, Gao T, Hu S, Lin B, Yan D, Xu Z, Zhang Z, Mao Y, Mao H, Wang L, Wang G, Xiong Y, Zuo B*. The functional SNPs in the 5' regulatory region of the porcine PPARD gene have significant association with fat deposition traits. PLoS One, 2015, 10(11): e0143734.
5. Zhang Y, Li W, Zhu M, Li Y, Xu Z*, Zuo B*. FHL3 differentially regulates the expression of MyHC isoforms through interactions with MyoD and pCREB. Cell Signal, 2016, 28(1): 60-73.
6. Huang WH, Xu ZY, Xiong YZ, Zuo B*. QTL analysis for carcass composition and meat quality traits on SSC7q1.1-q1.4 region in Large White × Meishan F2 pigs. Czech J Anim Sci, 2012 (6): 283-289.
7. Yang H#, Xu ZY#, Lei MG, Li FE, Deng CY, Xiong YZ, Zuo B*. Real-time reverse transcription-PCR expression profiling of porcine troponin I family in three different types of muscles during development. Mol Biol Rep, 2011, 38(3): 827-832.
8. Huang WH, Ma ZX, Xu ZY, Xiong YZ, Zuo B*. Detection of novel SNPs and mapping of the fatness QTL on pig chromosome 7q1.1-1.4 region. Genet Mol Res, 2011, 10(4):3090-3097.
9. Yang H, Xu ZY, Lei MG, Li FE, Deng CY, Xiong YZ, Zuo B*. Association of 3 polymorphisms in porcine troponin I genes (TNNI1 and TNNI2) with meat quality traits. J Appl Genet, 2010, 51(1): 51-57.
10. Yang H, Xu ZY, Ma ZX, Xiong YZ, Deng CY, Zuo B*. Molecular cloning and comparative characterization of the porcine troponin I family. Anim Biotechnol, 2010, 21(1): 64-76.
11. Li Y, Xu ZY, Li HY, Xiong YZ, Zuo B*. Differential transcriptional analysis between red and white skeletal muscle of Chinese Meishan pigs. Int J Biol Sci, 2010, 6(4): 350-360.
12. Xu ZY, Yang H, Li Y, Xiong YZ, Zuo B*. Temporal expression of TnI fast and slow isoforms in biceps femoris and masseter muscle during pig growth. Animal, 2010, 4(9): 1541-1546.
13. Xu ZY, Yang H, Xiong YZ, Deng CY, Li FE, Lei MG, Zuo B*. Identification of three novel SNPs and association with carcass traits in porcine TNNI1 and TNNI2. Mol Biol Rep, 2010, 37(7): 3609-3613.
14. Xu ZY, Xiong YZ, Lei MG, Li FE, Zuo B*. Genetic polymorphisms and preliminary association analysis with production traits of the porcine SLC27A4 gene. Mol Biol Rep, 2009, 36: 1427-1432.
15. Xu ZY, Nie P*, Chang MX, Sun BJ. Molecular cloning and expression analysis of SIMP (source of imunodominant MHC-associated peptides) in grass carp Ctenopharyngodon idella. Fish Shellfish Immun, 2008, 24: 701-14.
16. Xu ZY, Sun BJ, Chang MX, Nie P*. Characterization and expression analysis of TNFR-associated factor 1 (TRAF1) in grass carp Ctenopharyngodon idella. Vet Immunol Immunopathol, 2008, 121: 44-57.
17. Xu ZY, Nie P*, Sun BJ, Chang MX. Molecular Identification and Expression Analysis of Tumor Necrosis Factor 2 in Grass Carp Ctenopharyngodon idella. Acta Bioch Bioph Sin, 2007, 39: 857-68.
18. 楊華，徐珍，陳佳，姜佳佳，毛翠，毛慧敏，左波，徐在言*。豬FRZB、ABCF1 基因多態性與生長性狀的關聯分析。 中國畜牧雜誌， 2018, (1).
19. 胡閃耀，陳佳，姜佳佳，毛翠，毛慧敏，王利通，王國水，左波，徐在言*。大白豬FSHβ和RBP4基因多態性與繁殖性狀的相關性研究。豬業科學，2017，34（3）：108-112.
20. 徐在言，李媛，張雲霞。C2C12細胞中FHL3對不同肌纖維類型MyHC基因表達的影響。畜牧與獸醫，2012，44，150-151
科研項目
1. 優質轉基因豬新品種培育 2016.01
2. 優良種豬高效利用關鍵工程化技術集成與示範2014.01
3. FHL3基因調控肌肉不同纖維類型MyHC基因表達及其分子機制研究2011.01
4. 豬骨骼肌中FHL3蛋白相互作用轉錄因子鑑定及調控肌肉生長的信號通路研究 2009.01
榮譽獎項
作為主要完成人，獲授權國家發明專利1項。
