張梁，副教授，畢業於北京大學藥學院，現就職於茶與食品科技學院。2013.11-2014.11於University of Massachusetts Amherst從事博士後(訪問學者)工作，主要研究茶葉化學成分以及茶葉活性成分體內吸收代謝研究，主持7項省部級課題。以第一作者或者通訊作者在Comprehensive Reviews in Food Science and Food Safety, Journal of Agricultural and Food, Food Chemistry, Food Research International，Food & Function等SCI國際知名期刊學術論文30餘篇，發表論文被引用次數超過700次。受邀參與編著《Tea in Health and Disease Prevention》一書，以及受邀擔任Journal of Agricultural and Food Chemistry編委以及，多個國際刊物傑出審稿人。
基本介紹
- 中文名：張梁
- 外文名：Zhang Liang
- 別名：Zhang Liang
- 國籍：中國
- 民族：江西九江
- 職業：副教授
- 畢業院校：江西中醫學院 藥學系
- 所在單位：茶與食品科技學院
- 研究方向：： 茶葉化學成分及功效
人物經歷,主講課程,主要貢獻,
人物經歷
2000-2004 江西中醫學院 藥學系； 獲得學士學位。
2006-2007 上海中醫藥大學 藥劑學； 獲得碩士學位。
2007-2010 北京大學 天然產物化學； 獲得博士學位。
2011- ... 安徽農業大學，茶與食品科技學院，茶葉生物化學與生物技術重點實驗室。
2006-2007 上海中醫藥大學 藥劑學； 獲得碩士學位。
2007-2010 北京大學 天然產物化學； 獲得博士學位。
2011- ... 安徽農業大學，茶與食品科技學院，茶葉生物化學與生物技術重點實驗室。
主講課程
天然產物化學 、食品風味化學 、天然產物開發與利用 、現代生物學技術總論 、現代食品分離技術。
主要貢獻
科研情況：
構建EGCG代謝模型尋找黑茶中降脂活性成分和關鍵代謝菌株 國家自然科學基金委員會 青年基金 進行中 主持人。
茯磚茶由發花而產生的特有次生代謝產物及其抗菌活性研究 國家自然科學基金委員會 青年基金 進行中 參與人。
論文論著：
Zhang, L.*, Jânio Sousa Santos, Thiago Mendanha Cruz, Mariza Boscacci Marques, Mariana Araújo Vieira do Carmo, Luciana Azevedo, Yijun Wang, Daniel Granato*. Multivariate effects of Chinese keemun black tea grades (Camellia sinensis var. sinensis) on the phenolic composition, antioxidant, antihemolytic and cytotoxic/cytoprotection activities. Food Research International, 2019, 125, 108516.
Zhang, L.*, Chi-Tang Ho, Jie Zhou, Jânio Sousa Santos, Lorene Armstrong, Daniel Granato*. Chemistry and Biological Activities of Processed Camellia sinensis Teas: A Comprehensive Review. Comprehensive Reviews in Food Science and Food Safety, 2019, doi: 10.1111/1541-4337.12479.
Zhang, L., Sheng, J., Long, P., Meng, Q., Wan, X., & Zhang, Z. (2019). The comparative study on the absorption and excretion of caffeine in rats orally administered ripened and green Pu-erh tea. Progress in Nutrition, 21, 471-477.
Meng, Q., Long, P., Zhou, J., Ho, C.-T., Zou, X., Chen, B., & Zhang, L*. (2019). Improved absorption of beta-carotene by encapsulation in an oil-in-water nanoemulsion containing tea polyphenols in the aqueous phase. Food Research International, 116, 731-736.
Zhou, J., Wu, Y., Long, P., Ho, C.-T., Wang, Y., Kan, Z., Cao, L., Zhang, L. *, & Wan, X. (2019). LC-MS-Based Metabolomics Reveals the Chemical Changes of Polyphenols during High-Temperature Roasting of Large-Leaf Yellow Tea. Journal of Agricultural and Food Chemistry, 67(19), 5405-5412.
Zhou, J., Ho, C.-T., Long, P., Meng, Q., Zhang, L. *, & Wan, X. (2019). Preventive Efficiency of Green Tea and Its Components on Nonalcoholic Fatty Liver Disease. Journal of Agricultural and Food Chemistry, 67(19), 5306-5317.
Xi, J. †, Zhang, L. †, Peng, C., Zhou, J., Peng, Y., Xu, L., Chen, B., Meng, Q., Hou, R., Li, D., Zhang, Y., Wan, X., & Cai, H. (2019). Flavor augmentations affect fluoride bioavailability from brewed dark tea. Lwt-Food Science and Technology, 109, 270-275.
Zhou, J. †, Zhang, L. †, Meng, Q., Wang, Y., Long, P., Ho, C.-T., Cui, C., Cao, L., Li, D., & Wan, X. (2018). Roasting improves the hypoglycemic effects of a large-leaf yellow tea infusion by enhancing the levels of epimerized catechins that inhibit alpha-glucosidase. Food & Function, 9(10), 5162-5168.
Zhang, S.†, Zhang, L.†, Wang, Y.†, Yang, J., Liao, M., Bi, S., Xie, Z., Ho, C.-T., & Wan, X. (2018). TBC2target: A Resource of Predicted Target Genes of Tea Bioactive Compounds. Frontiers in plant science, 9.
Cao, L., Guo, X., Liu, G., Song, Y., Ho, C.-T., Hou, R., Zhang, L.*, & Wan, X. (2018). A comparative analysis for the volatile compounds of various Chinese dark teas using combinatory metabolomics and fungal solid-state fermentation. Journal of Food and Drug Analysis, 26(1), 112-123.
Chen, B., Zhou, J., Meng, Q., Zhang, Y., Zhang, S., & Zhang, L*. (2018). Comparative analysis of fecal phenolic content between normal and obese rats after oral administration of tea polyphenols. Food & Function, 9(9), 4858-4864.
Peng, Y., Meng, Q., Zhou, J., Chen, B., Xi, J., Long, P., Zhang, L. *, & Hou, R. (2018). Nanoemulsion delivery system of tea polyphenols enhanced the bioavailability of catechins in rats. Food Chemistry, 242, 527-532.
Guo, X., Long, P., Meng, Q., Ho, C.-T., & Zhang, L*. (2018). An emerging strategy for evaluating the grades of Keemun black tea by combinatory liquid chromatography-Orbitrap mass spectrometry-based untargeted metabolomics and inhibition effects on alpha-glucosidase and alpha-amylase. Food Chemistry, 246, 74-81.
Chen, B., Long, P., Sun, Y., Meng, Q., Liu, X., Cui, H., Lv, Q., & Zhang, L*. (2017). The chemical profiling of loquat leaf extract by HPLC-DAD-ESI-MS and its effects on hyperlipidemia and hyperglycemia in rats induced by a high-fat and fructose diet. Food & Function, 8(2), 687-694.
Zhang, L., Tai, Y., Wang, Y., Meng, Q., Yang, Y., Zhang, S., Yang, H., Zhang, Z., Li, D., & Wan, X. (2017). The proposed biosynthesis of procyanidins by the comparative chemical analysis of five Camellia species using LC-MS. Scientific Reports, 7.
Zhang, L., Wang, Y., Li, D., Ho, C.-T., Li, J., & Wan, X. (2016). The absorption, distribution, metabolism and excretion of procyanidins. Food & Function, 7(3), 1273-1281.
Zhang, L., Han, Y., Shan, J., Liang, Y., Xu, L., Zhang, S., Li, J., & Wan, X. (2015). Simultaneous determination of seven catechins in rat plasma by ultra-high performance liquid chromatography tandem mass spectrometry and its application to a pharmacokinetics study. Analytical Methods, 7(22), 9415-9420.
Zhang, L., Han, Y., Xu, L., Liang, Y., Chen, X., Li, J., & Wan, X. (2015). The effects of co-administration of butter on the absorption, metabolism and excretion of catechins in rats after oral administration of tea polyphenols. Food & Function, 6(7), 2249-2256.
Zhang, L., Deng, W.-W., & Wan, X.-c. (2014). Advantage of LC-MS metabolomics to identify marker compounds in two types of Chinese dark tea after different post-fermentation processes. Food Science and Biotechnology, 23(2), 355-360.
Zhang, L., Zhang, Z.-z., Zhou, Y.-b., Ling, T.-j., & Wan, X.-c. (2013). Chinese dark teas: Postfermentation, chemistry and biological activities. Food Research International, 53(2), 600-607.
Zhang, L., Wan-fang Shao, Li-feng Yuan, Peng-fei Tu, Zhi-zhong Ma. Decreasing pro-inflammatory cytokine and reversing the immunosenescence with extracts of Pu-erh tea in senescence accelerated mouse (SAM). Food Chemistry, 2012, 135 (4): 2222–2228.
Zhang, L., Zhi-Zhong Ma, Yan-Yun Che, Ning Li, Peng-Fei Tu, Protective effect of a new amide compound from Pu-erh tea on human microvascular endothelial cell against cytotoxicity induced by hydrogen peroxide, Fitoterapia, 2011, 82(2), 267-271.
Zhang, L., Ning Li, Yan-Yun Che, Zhi-zhong Ma, Peng-Fei Tu. Development of the fingerprints of aged Pu-erh tea and ripened Pu-erh tea by high-performance liquid chromatography, Journal of Chinese Pharmaceutical Sciences, 2011, 20(4): 351-357.
Zhang, L., Ning Li, Zhi-Zhong Ma, Peng-Fei Tu. Comparison of the chemical constituents of aged Pu-erh tea, ripened Pu-erh tea and other teas using HPLC-DAD-ESI-MSn. Journal of Agricultural and Food Chemistry, 2011, 59 (16): 8754–8760.
Xu, L., Liang, Y., Chen, X., Chen, B., Han, Y., & Zhang, L. * (2015). Hyperlipidemia affects the absorption, distribution and excretion of seven catechins in rats following oral administration of tea polyphenols. RSC Advances, 5(119), 97988-97994.
Yang, J.-H. †, Zhang, L. †, Li, J.-S., Chen, L.-H., Zheng, Q., Chen, T., Chen, Z.-P., Fu, T.-M., & Di, L.-Q. (2015). Enhanced oral bioavailability and prophylactic effects on oxidative stress and hepatic damage of an oil solution containing a rosmarinic acid-phospholipid complex. Journal of Functional Foods, 19, 63-73.
Zhou, J. †, Zhang, L. †, Zhang, J., & Wan, X. (2014). Aqueous extract of post-fermented tea reverts the hepatic steatosis of hyperlipidemia rat by regulating the lipogenic genes expression and hepatic fatty acid composition. Bmc Complementary and Alternative Medicine, 14.
Qian, X.-C. †, Zhang, L. †, Tao, Y., Huang, P., Li, J.-S., Chai, C., Li, W., Di, L.-Q., & Cai, B.-C. (2015). Simultaneous determination of ten alkaloids of crude and wine-processed Rhizoma Coptidis aqueous extracts in rat plasma by UHPLC-ESI-MS/MS and its application to a comparative pharmacokinetic study. Journal of Pharmaceutical and Biomedical Analysis, 105, 64-73.
Weinan Wang†, Zhang, L.†, Shu Wang, Shepo Shi, Yong Jiang, Ning Li, Pengfei Tu, 8-C N-ethyl-2-pyrrolidinone substituted flavan-3-ols as the marker compounds of Chinese dark teas formed in the post-fermentation process provide significant antioxidative activity, Food Chemistry, 2014, 152(1), 539-545.
Huang, P. †, Zhang, L. †, Chai, C., Qian, X.-C., Li, W., Li, J.-S., Di, L.-Q., & Cai, B.-C. (2014). Effects of food and gender on the pharmacokinetics of ginkgolides A, B, C and bilobalide in rats after oral dosing with ginkgo terpene lactones extract. Journal of Pharmaceutical and Biomedical Analysis, 100, 138-144.
