宋麗艷,女 ,博士,研究員,暨南大學藥學院博士生導師。
基本介紹
- 中文名:宋麗艷
- 國籍:中國
- 民族:漢
- 職業:教師
個人簡介,科研情況,
個人簡介
在高校從事教學與科研工作30餘年。教學方面主要承擔國際學院藥學專業《生物藥劑學與藥物動力學》等課程的全英教學工作;科研方面主要從事腫瘤與免疫藥理學研究以及中藥有效成分篩選與作用機制研究。發表學術論文38篇(其中SCI期刊收錄論文17篇),參編教材/學術專著8部,申請發明專利4項。主持或參加國家級與省部級科研課題10餘項。
科研情況
主要研究方向:
1. 腫瘤與免疫藥理學
2. 中藥藥效及分子生物學基礎
3. 創新藥物的研究和開發
近年來承擔的主要科研項目:
1.國家自然科學基金面上項目(81374015):海洋中藥毛蚶抗腫瘤活性物質基礎及其作用機制研究,資助經費70萬元(課題負責人)
2.“十二五”國家科技重大專項/重大新藥創製課題(2011ZX09102-001-33):抗腫瘤生物新藥ACM,研究經費300萬元(課題負責人)
3.“十一五”國家科技重大專項/重大新藥創製課題(2009ZX09103-726):抗腫瘤海洋生物新藥JNY-1,研究經費150萬元(子課題負責人)
5.廣東省科技計畫重大專項課題(2004A30505003):抗癌新藥注射用JNY-1凍乾粉針
的研製開發,研究經費40萬元(藥效與毒理學研究負責人)
6.廣州市科技計畫項目課題(2006Z3-E5031):抗癌中藥新藥ACM膠囊的研製開發,
研究經費30萬元(課題負責人)
7.廣州市科技計畫重點課題(2005Z2-E4031):抗癌新藥注射用JNY-1凍乾粉針的研
制開發,研究經費50萬元(藥效與毒理學研究負責人)
近五年代表性論著或專利(或通訊作者):
1.Lili Chen, Liyan Song*, Tingfei Li, Jianhua Zhu, Jian Xu, Qin Zheng, Rongmin Yu. A new antiproliferative and antioxidant peptide isolated from Arca subcrenata. Mar Drugs 2013, 11:1800-1814.
2.Xianjing Hu, Liyan Song*, Lijiao Huang, Qin Zheng, Rongmin Yu. Antitumor effect of a polypeptide fraction from Arca subcrenata in vitro and in vivo. Mar Drugs 2012, 10:2782-2794.
3.Li Yang, Jianhua Zhu, Liyan Song*, Xiaojian Shi, Xingyi Li, Rongmin Yu. Three sesquiterpene compounds biosynthesized from artemisinic acid using suspension-cultured cells of Averrhoa carambola. Nat Prod Res 2012, 26:1388-1394.
4.Liangbin Zhou, Tian Tian, Bailin Xue, Liyan Song*, Ling Liu, Rongmin Yu. Biosynthesis of coumarin glycosides by transgenic hairy roots of Polygonum multiflorum. Biosci Biotechnol Biochem 2012, 76:1008-1010.
5.Xuqiao Hu, Yuanyuan Huang, Quanfeng Dong, Liyan Song*, Fei Yuan, Rongmin Yu. Structure characterization and antioxidant activity of a novel polysaccharide isolated from pulp tissues of Litchi chinensis. J Agric Food Chem 2011, 59:11548-11552.
6.Yin Yin, Rongmin Yu, Wei Yang, Fei Yuan, Chunyan Yan, Liyan Song*. Structural characterization and anti-tumor activities of a heteropolysaccharide isolated from Taxus yunnanensis. Carbohydr Polym 2010, 82:543-548.
7.Fei Yuan, Rongmin Yu, Yin Yin, Jianru Shen, Quanfeng Dong, Ling Zhong, Liyan Song*. Structure characterization and antioxidant activity of a novel polysaccharide isolated from Ginkgo biloba. Int J Biol Macromol 2010, 46:436-439.
8.Rongmin Yu, Yin Yin, Wei Yang, Weili Ma, Lin Yang, Xiujuan Chen, Zhang Zhang, Bin Ye, Liyan Song*. Structural elucidation and biological activity of a novel polysaccharide by alkaline extraction from cultured Cordyceps militaris. Carbohydr Polym 2009, 75:166-171.
9.Liyan Song, Tingfei Li, Rongmin Yu, Chunyan Yan, Shengfang Ren, Yu Zhao. Antioxidant activities of hydrolysates of Arca subcrenata prepared with three proteases. Mar Drugs 2008, 6:607-619.
10.Liyan Song, Shengfang Ren, Rongmin Yu, Chunyan Yan, Tingfei Li, Yu Zhao. Purification, characterization and in vitro anti-tumor activity of proteins from Arca subcrenata Lischke. Mar Drugs 2008, 6:418-430.