基本介紹
- 中文名：孫青竹
- 出生日期：1984年3月
- 畢業院校：西安交通大學
- 學位/學歷：博士
- 職業：教師
- 專業方向：生物學
- 任職院校：西北農林科技大學
人物經歷,研究方向,開設課程,主持項目,學術成果,
人物經歷
2007-2012年，西安交通大學醫學部，獲生物學博士學位。
2012年8月-2016年8月，西安交通大學醫學部基礎醫學院，講師；
2014年9月-2016年10月，瑞士巴塞爾大學，博士後；
2016年10月至今，西北農林科技大學動物科技學院，副教授。
研究方向
營養元素參與表觀遺傳調控的機制研究。
開設課程
承擔本科生《動物營養學》課程和研究生《動物營養生理學》、《動物分子營養學》課程。
主持項目
西北農林科技大學引進人才啟動經費項目，2016.10—2021.10；60萬元。在研，項目主持人；
國家自然科學基金青年科學基金項目；項目號：31601033；2017.1—2019.12；22萬元。在研，項目主持人。
陝西省自然科學基礎研究計畫面上項目；項目號：2015JM8448；2015.1-2016.12；2萬元。在研，項目主持人。
中國博士後科學基金第52批面上項目；項目號：2012M521754； 2013.1—2014.12；5萬元。已結題，項目主持人。
西安交通大學基本科研業務費自由探索項目；項目號：DWYXc111000117；2013.1-2015.12；5萬元。已結題，項目主持人。
西安交通大學“新教師科研支持計畫”； 2012.9—2014.12；10萬元。已結題，項目主持人。
學術成果
Qingzhu Sun, Li Liu, Daiana Stolz, Michael Tamm, Shemin Lu, Michael Roth* Constitutive high expression of PRMT1 in asthmatic airway smooth muscle cells is caused by reduced MicroRNA-19a and leads to enhanced remodeling.2016Journal of allergy and clinical immunology,IF= 12.485
Qingzhu Sun, Li Liu, Daiana Stolz, Michael Tamm, Shemin Lu, Michael Roth* PDGF-BB Induces PRMT1 Expression through ERK1/2 Dependent STAT1 Activation and Regulates Remodeling in Primary Human Lung Fibroblasts. Cellular Signalling 2016 Apr;28(4):307-15. IF= 4.243
Li Liu, Qingzhu Sun, Rujuan Bao, Michael Roth, Bo Zhong, Xi Lan, Jia Tian, Qirui He, Dongmin Li, Jian Sun, Xudong Yang, Shemin Lu*. Cell type specific regulation of PRMT1 expression by PIAS1 and RKIP in epithelium and fibroblasts in acute and chronic antigen induced pulmonary inflammation. Scientific Reports - Nature, Accepted, Co-first Author IF= 5.578
Qingzhu Sun, Li Liu, Michael Roth, Rujuan Bao, Jia Tian, Qirui He, Xi Lan, Congshan Jiang, Bo Zhong, Jian Sun, Xudong Yang*, Shemin Lu* PRMT1 upregulated by epithelial proinflammatory cytokines participates in COX2 expression in fibroblasts and chronic antigen-induced pulmonary inflammation. The Journal of Immunology 2015 Jul 1;195(1):298-306. IF= 5.264
Sun Qingzhu, Yang Xudong, Zhong Bo, Jiao Fangfang, Li Chenyan, Li Dongmin, Lan Xi, Sun Jian, Lu Shemin. Upregulated Protein Arginine Methyltransferase 1 by IL-4 Increases Eotaxin-1 Expression in Airway Epithelial Cells and Participates in Antigen-Induced Pulmonary Inflammation in Rats[J]. The Journal of Immunology, 2012 Apr 1, 188(7):3506-12. IF= 5.264
Qingzhu Sun, Xudong Yang, Raza Asim M B, Fangfang Jiao, Shemin Lu. Different challenge terms determine disease patterns of antigen induced pulmonary inflammation in E3 rats [J]. AMPIS, 2011 April/May, 119(4-5), 229–238. IF= 2.042
孫青竹，焦芳芳，楊旭東，鐘波，蔣梅花，李國良，呂彬，呂社民. PRMTs在E3大鼠哮喘模型中表達變化的研究[J]. 南方醫科大學學報，2010. 30(4): 716-719.（Medline收錄）
Lan X, Yan J, Ren J, Zhong B, Li J, Li Y, Liu L, Yi J, Sun Q, Yang X, Sun J, Meng L, Zhu W, Holmdahl R, Li D, Lu S. A novel long noncoding RNA Lnc-HC binds hnRNPA2B1 to regulate expressions of Cyp7a1 and Abca1 in hepatocytic cholesterol metabolism. Hepatology. 2015 Dec 11. doi: 10.1002/hep.28391. IF= 11.055
Jiang C, Yu H, Sun Q, Zhu W, Xu J, Gao N, Zhang R, Liu L, Wu X, Yang X, Meng L, Lu S. Extracellular microRNA-21 and microRNA-26a increase in body fluids from rats with antigen induced pulmonary inflammation and children with recurrent wheezing. BMC Pulm Med. 2016 Apr 14;16:50. doi: 10.1186/s12890-016-0216-2.
Jian Sun, Qingzhu Sun, Shemin Lu. From selenoprotein to endochondral ossification: A novel mechanism with microRNAs potential in bone related diseases? [J] Medical Hypotheses. 2011 Nov, 77(5), 807–811. IF=″1.389
Xudong Yang, Qingzhu Sun, Raza Asim, Xiaogang Jiang, Bo Zhong, Shemin Lu. Nitric oxide both in brochoalveolar lavage fluid and serum is associated with pathogenesis and severity of antigen- induced pulmonary inflammation in rats[J]. Journal of asthma, 2010 Mar, 47(2):135-44. IF=″1.372.
Zhong B, Yang X, Sun Q, Liu L,Lan X, Tian J, He Q, Hou W, Liu H, Jiang C, Gao N, Lu S. Pdcd4 modulates markers of macrophage alternative activation and airway remodeling in antigen-induced pulmonary inflammation. J Leukoc Biol. 2014 Dec;96(6):1065-75.
Katrin E Hostettler, Jun Zhong, Eleni Papakonstantinou, George Karakiulakis, Michael Tamm, Petra Seidel, Qingzhu Sun, Jyotshna Mandal, Didier Lardinois, Christopher Lambers, Michael Roth. Anti-fibrotic effects of nintedanib in lung fibroblasts derived from patients with idiopathic pulmonary fibrosis. Respiratory Research 2014, 15:157
Zixin Min; Wenxiang Zhao; Nannan Zhong; Yuanxu Guo; Qingzhu Sun; Quancheng Wang; Rui Zhang; Jidong Yan; Lifang Tian; Fujun Zhang; Yan Han; Qilan Ning; Liesu Meng; Jian Sun*; Shemin Lu*. Abnormality of epiphyseal plate induced by selenium deficiency diet in two generation DA rats. APMIS. 2015 May 25. doi: 10.1111/apm.12404.
Liesu Meng, Xiaojing He, Wenhua Zhu, Xudong Yang, Congshan Jiang, Qingzhu Sun, Asim Raza M.B., Simeng Zhang, Qian Xue, Xinfang Xie, Shemin Lu. TLR3 and TLR7 modulate IgE production in antigen induced pulmonary inflammation via influencing IL-4 expression in immune organs[J]. PLoS ONE. 2011. 6(2): e17252. IF=″4.351
Dongmin Li, XuanWang, Xi Lan, Yue Li, Li Liu, Jing Yi, Jing Li, Qingzhu Sun, Yili Wang, Hongmin Li, Nannan Zhong, Rikard Holmdahl, Shemin Lu. Down-regulation of miR-144 elicits proinflammatory cytokine production by targeting toll-like receptor 2 in nonalcoholic steatohepatitis of high-fat-diet-induced metabolic syndrome E3 rats. Molecular and Cellular Endocrinology 402 (2015) 1–12
Jian Sun, Nannan Zhong, Qibin Li, Zixin Min, Wenxiang Zhao, Qingzhu Sun, Lifang Tian, Hang Yu, Qian Shi, Fujun Zhang, Shemin Lu. MicroRNA of rats articular cartilage at different developmental stages identified by Solexa sequencing [J]. Osteoarthritis and Cartilage. 2011. 19(10):1237-1245. IF=″3.953
Shahzad M, Yang X, Raza Asim MB, Sun Q, Han Y, Zhang F, Cao Y, Lu S. Black seed oil ameliorates allergic airway inflammation by inhibiting T-cell proliferation in rats. Pulm Pharmacol Ther[J]. 2009; 22(1):37-43. IF= 2.09
Raza Asim M B, Xudong Yang, Muhammad Shahzad, Qingzhu Sun, Fujun Zhang, Yan Han and Shemin Lu. Role of arginase pathway in lung remodeling through the downstream products in antigen induced pulmonary inflammation of E3 rats[J]. Swiss Medical Weekly, 2010; 140:w13128. IF= 1.82
李晨燕，孫青竹，楊旭東，鐘波，韓燕，呂社民。人PRMT1基因真核載體的構建與鑑定[J]. 細胞與分子免疫學雜誌，2012.28(4): 384-7. (Medline收錄)
韓燕; 張歡; 寧啟蘭; 鐘波; 孫青竹; 溫玉榮; 高成閣; 馬捷. 中國漢族女性中G72 基因與精神分裂症的關係[J]. 第二軍醫大學學報，2010.31(8): 826-829. (核心期刊)
