孫欽儒,男,博士,西安交通大學醫學部講師。
基本介紹
- 中文名:孫欽儒
- 學位/學歷:博士
- 職業:教師
- 專業方向:人體解剖與組織胚胎學
- 任職院校:西安交通大學
- 職稱:講師
個人經歷,研究方向,學術成果,科研項目,專利、論文,
個人經歷
2014.10-現在 西安交通大學醫學部法醫學院 講師
2016.9-現在 西安交通大學臨床醫學博士站 博士後
研究方向
線粒體穩態和細胞能量代謝功能在神經退行性疾病和精神行為異常中的作用機制。
學術成果
科研項目
1.國家自然科學基金青年項目(81500927),2016.01-2018.12,17.5萬元
2.陝西省自然科學基金面上項目(2017JM8017),2017.01-2018.12,5萬元
3.中國博士後基金特別資助(2018T111074),2018.03-2019.12,15萬元
4.中國博士後基金面上資助(2017M623190),2017.10-2019.03,5萬元
5.陝西省博士後科研項目資助(公示中),2018.03-2019.08,5萬元
6.西安交通大學省重點實驗室青年學術骨幹培植項目,2015.09-2016.09,15萬元
7.西安交通大學“新教師科研支持計畫”,2015.04-2017.04,15萬元
專利、論文
[1]Sun Q; Jia N; Yang J; Chen G. Nrf2 Signaling Pathway Mediates the Antioxidative Effects of Taurine Against Corticosterone-Induced Cell Death in HUMAN SK-N-SH Cells, Neurochem Res, 2018
[2]Yu Q, Wang Y, Du F, Yan S, Hu G, Origlia N, Rutigliano G,Sun Q, Yu H, Ainge J, Yan SF, Gunn-Moore F, Yan SS.Overexpression of endophilin A1 exacerbates synaptic alterations in a mouse model of Alzheimer's disease.Nat Commun. 2018
[3]Jia N,Sun Q, Su Q, Dang S, Chen G. Taurine promotes cognitive function in prenatally stressed juvenile rats via activating the Akt-CREB-PGC1α pathway.Redox Biol. 2016 (共同通訊作者)
[4] Jia N,Sun Q, Su Q, Chen G. SIRT1-mediated deacetylation of PGC1α attributes to the protection of curcumin against glutamate excitotoxicity in cortical neurons.Biochem Biophys Res Commun. 2016 (共同通訊作者)
[5]Valasani KR,Sun Q, Fang D, Zhang Z, Yu Q, Guo Y, Li J, Roy A, ShiDu Yan S. Identification of a Small Molecule Cyclophilin D Inhibitor for Rescuing Aβ-Mediated Mitochondrial Dysfunction.ACS Med Chem Lett.2016(共同第一作者)
[6]Fang D, Wang Y, Zhang Z, Du H, Yan S,Sun Q, Zhong C, Wu L, Vangavaragu JR, Yan S, Hu G, Guo L, Rabinowitz M, Glaser E, Arancio O, Sosunov AA, McKhann GM, Chen JX, Yan SS.Increased neuronal PreP activity reduces Aβ accumulation, attenuates neuroinflammation and improves mitochondrial and synaptic function in Alzheimer disease's mouse model.Hum Mol Genet.2015
[7]Sun Q, Jia N, Wang W, Jin H, Xu J, Hu H. Protective Effects of Astragaloside IV against Amyloid Beta1-42 Neurotoxicity by Inhibiting the Mitochondrial Permeability Transition Pore Opening[J].PLoS One. 2014
[8]Sun Q, Hu H, Wang W, Jin H, Feng G, Jia N. Taurine attenuates amyloid β 1-42-induced mitochondrial dysfunction by activating of SIRT1 in SK-N-SH cells[J].Biochem Biophys Res Commun, 2014
[9]Sun Q, Jia N, Wang W, Jin H, Xu J, Hu H. Activation of SIRT1 by curcumin blocks the neurotoxicity of amyloid-<beta>25-35 in rat cortical neurons[J].Biochem Biophys Res Commun, 2014(共同第一作者)
[10]Valaasani KR,Sun Q, Hu G, Li J, Du F, Guo Y, Carlson EA, Gan X, Yan SS. Identification of Human ABAD Inhibitors for Rescuing Abeta-Mediated Mitochondrial Dysfunction[J]. Curr Alzheimer Res, 2014(共同第一作者)