天津大學教授、博導，國家優青，天津市海河英才計畫入選者，天津大學北洋英才計畫入選者。畢業於中國科學院與哈佛大學並獲得博士學位。智慧型材料與生物製造實驗室負責人，重點針對腫瘤、神經系統疾病、組織/器官損傷等臨床面臨的棘手問題，融合材料學、生物學、醫學的研究，設計開發具有良好生物相容性與生物活性的智慧型材料，發展新型生物製造工藝，研究其在生命系統中的行為與作用，探索針對腫瘤、神經系統疾病、組織/器官損傷以及其他重大疾病的創新治療策略。
在Nat. Commun.、Sci. Transl. Med.、 PNAS、Matter、Adv. Mater.、Angew. Chem. Int. Edit.、Chem. Soc. Rev.等學術期刊發表論文60餘篇, 其中18篇論文入圍“ESI高被引論文”，2篇論文入圍“ESI熱點論文”，8篇封面論文，所發表論文他引5000餘次。授權專利10餘項。主持國家自然科學基金優秀青年基金、面上項目、青年科學基金項目、省市科技項目等10餘項。應邀擔任多個SCI副主編、客座主編、期刊編委、學術編輯，擔任國家自然科學基金、科技部重點研發計畫、廣東省、河南省、天津市、廣州市、深圳市等科學基金項目會評/函評專家。
基本介紹
人物經歷,研究方向,科研項目,學術代表作,獲獎情況,社會學術兼職,
人物經歷
2021.01，天津大學，教授，博士生導師
2018.01-2020.12，中山大學，特聘研究員
2013.09-2017.12，中國科學院大學/哈佛大學，博士
2010.09-2013.06，中國科學院大學，碩士
研究方向
(1) 智慧型材料設計（仿生生物材料、納米生物材料、能量轉換材料、異質結催化系統、多功能藥物載體等）
(2) 智慧型材料的生物製造（3D列印、靜電紡絲等）
(3) 腫瘤診療一體化（催化治療、免疫治療、藥物載體、基因治療、螢光/超聲/MRI/C成像等）
(4) 組織/器官損傷修復（生物活性類組織/類器官、多功能水凝膠、智慧型敷料等）
(5) 智慧型納米機器人構建與疾病防治（基於腸道微生物的“盔甲”+“導航”+“動力”系統構建）
科研項目
(1) 國家自然科學基金委員會，優秀青年項目，2022-01至2024-12，200萬，在研，主持
(2) 國家自然科學基金委員會，面上項目，32071322， 2021-01至2024-12，62萬元，在研，主持
(3) 國家自然科學基金委員會，青年項目，81801826, 2019-01至2021-12，21萬，在研，主持
(4) 天津市共建師資隊伍， 2021-01至2023-12，100萬，在研，主持
(5) 天津大學自主創新基金， 2021-01至2021-12，30萬，在研，主持
(6) 深圳市科技創新委員會，面上項目，JCYJ 202103243002410, 2021-01至2023-12，50萬，在研，主持
(7) 深圳市科技創新委員會，面上項目，JCYJ20180307153300735, 2019-01至2021-12，50萬，在研，主持
(8) 中山大學高校基本業務費，青年教師培育項目，2020-01至2022-12，20萬，在研，主持
(9) 國家自然科學基金委員會，面上項目，21676276，2017-01至2020-12，64萬元，已結題，參加
(10) 國家自然科學基金委員會，重大研究計畫，91534126，2016-01至2018-12，80萬元，已結題，參加
(11) 國家自然科學基金委員會，面上項目，21376249，2014-01至2017-12，80萬元，已結題，參加
學術代表作
(1) Yong Kang, Zhuo Mao, Ying Wang, Chao Pan, Meitong Ou, Hanjie Zhang, Xiaoyuan Ji*. Design of a two-dimensional interplanar heterojunction for catalytic cancer therapy. Nature Communications, 2022, 13, 2425.
(2) Weiwei Zeng, Hanjie Zhang, Xue Yuan, Ting Chen, Zhengcun Pei, Xiaoyuan Ji*. Two-Dimensional Nanomaterial-based catalytic Medicine: Theories, advanced catalyst and system design. Advanced Drug Delivery Reviews, 2022, 184, 114241.
(3) Chao Pan, Zhuo Mao, Xue Yuan, Hanjie Zhang, Lin Mei, Xiaoyuan Ji*. Heterojunction Nanomedicine, Advanced Science, 2022, 9, 2105747.
(4) Meitong Ou, Chuchu Lin, Ying Wang, Yuting Lu, Wenyan Wang, Zimu Li, Weiwei Zeng, Xiaowei Zeng, Xiaoyuan Ji*, Lin Mei, Heterojunction engineered bioactive chlorella for cascade promoted cancer therapy, Journal of Controlled Release, 2022, 345, 755.
(5) Yong Kang, Na Kong, Meitong Ou, Ying Wang, Qicai Xiao, Lin Mei, Bing Liu, Liqun Chen, Xiaobin Zeng, Xiaoyuan Ji*. A Novel Cascaded Energy Conversion System Inducing Efficient and Precise Cancer Therapy. Bioactive Materials, 2022.
(6) Na Kong, Hanjie Zhang, Chan Feng, Chuang Liu, Yufen Xiao, Lin Mei, Wei Tao, Xiaoyuan Ji*. Arsenene-mediated multiple independently targeted reactive oxygen species burst for cancer therapy, Nature Communications, 2021, 12, 4777.
(7) Xiaoyuan Ji, Lanlan Ge, Liu Chuang, Zhongmin Tang, Yufen Xiao, Wei Chen, Zhouyue Lei, Wei Gao, Sara Blake, Diba De, Bingyang Shi, Xiaobing Zeng, Na Kong, Xingcai Zhang, Wei Tao*. Capturing functional two-dimensional nanosheets from sandwich-structure vermiculite for cancer theranostics, Nature Communications, 2021, 12: 1124.
(8) Kang, Yong; Lei, Lei; Zhu, Chunfeng; Zhang, Hanjie; Mei, Lin; Ji, Xiaoyuan*; Piezo-photocatalytic effect mediating reactive oxygen species burst for cancer catalytic therapy, Materials Horizons, 2021, 8, 2273.
(9) Meitong Ou, Liu Yu, Wei Tao, Xiaoyuan Ji*, Lin Mei. The Emergence and Evolution of Borophene. Advanced Science, 2021, 2001801.
(10) Feng, Chan; Ouyang, Jiang; Tang, Zhongmin; Kong, Na; Liu, Yuan; Fu, LiYi; Ji, Xiaoyuan*; Xie, Tian*; Farokhzad, Omid C.; Tao, Wei*; Germanene-Based Theranostic Materials for Surgical Adjuvant Treatment: Inhibiting Tumor Recurrence and Wound Infection, Matter, 2020, 3(1): 127-144.
(11) Pan, Chao; Ou, Meitong; Cheng, Qinzhen; Zhou, Yun; Yu, Yongkang; Li, Zimu; Zhang, Fan; Xia, Dehua; Mei, Lin; Ji, Xiaoyuan*; Z-Scheme Heterojunction Functionalized Pyrite Nanosheets for Modulating Tumor Microenvironment and Strengthening Photo/Chemodynamic Therapeutic Effects, Advanced Functional Materials, 2020, 30(3): 1906466.
(12) Ouyang, Jiang#; Ji, Xiaoyuan#; Zhang, Xingcai; Feng, Chan; Tang, Zhongmin; Kong, Na; Xie, Angel; Wang, Junqing; Sui, Xinbing; Deng, Liu; Liu, Younian; Kim, Jong Seung; Cao, Yihai; Tao, Wei*; In situ sprayed NIR-responsive, analgesic black phosphorus-based gel for diabetic ulcer treatment, Proceedings of the National Academy of Sciences of the United States of America, 2020, 117(46): 28667-28677.
(13) Ji, Xiaoyuan; Kang, Yong; Fan, Taojian; Xiong, Qingqing; Zhang, Songping*; Tao, Wei*; Zhang, Han*; An antimonene/Cp*Rh(phen)Cl/black phosphorus hybrid nanosheet-based Z-scheme artificial photosynthesis for enhanced photo/bio-catalytic CO2 reduction, Journal of Materials Chemistry A, 2020, 8(1): 323-333.
(14) Ou, Meitong; Pan, Chao; Yu, Yongkang; Wang, Xuan; Zhou, Yun; Zhang, Hanjie; Cheng, Qinzhen; Wu, Meiying; Ji, Xiaoyuan*; Mei, Lin*; Two-dimensional highly oxidized ilmenite nanosheets equipped with Z-scheme heterojunction for regulating tumor microenvironment and enhancing reactive oxygen species generation, Chemical Engineering Journal, 2020, 390: 124524.
(15) Weiwei Zeng, Hanjie Zhang, Yimin Deng, Aiting Jiang, Xiaoyan Bao, Minqi Guo, Zimu Li, Meiying Wu, Xiaoyuan Ji*, Xiaowei Zeng*, Lin Mei*. Dual-response oxygen-generating MnO2 nanoparticles with polydopamine modification for combined photothermal-photodynamic therapy. Chemical Engineering Journal, 2020, 389, 124494.
(16) Wei Tao*#, Na Kong#, Xiaoyuan Ji#, Yupeng Zhang, Amit Sharma, Jiang Ouyang, Baowen Qi, Chulhun Kang*, Han Zhang*, Omid C. Farokhzad, Jong Seung Kim*. Emerging Two-dimensional Monoelemental Materials (Xenes) for Biomedical Applications. Chemical Society Reviews, 2019, 48, 2891.
(17) Ji, Xiaoyuan; Kang, Yong; Ouyang, Jiang; Chen, Yunhan; Artzi, Dolev; Zeng, Xiaobin; Xiao, Yuling; Feng, Chan; Qi, Baowen; Kim, Na Yoon; Saw, Phei Er; Kong, Na; Farokhzad, Omid C.*; Tao, Wei*; Synthesis of Ultrathin Biotite Nanosheets as an Intelligent Theranostic Platform for Combination Cancer Therapy, Advanced Science, 2019, 6(19): 1901211.
(18) Zhang, Hanjie; Zeng, Weiwei; Pan, Chao; Feng, Liwen; Ou, Meitong; Zeng, Xiaowei; Liang, Xin; Wu, Meiying; Ji, Xiaoyuan*; Mei, Lin; SnTe@MnO2‐SP Nanosheet–Based Intelligent Nanoplatform for Second Near‐Infrared Light–Mediated Cancer Theranostics, Advanced Functional Materials, 2019, 29(37): 1903791.
(19)Ji, Xiaoyuan; Kong, Na; Wang, Junqing; Li, Wenliang; Xiao, Yuling; Gan, Silvia Tian; Zhang, Ye; Li, Yujing; Song, Xiangrong; Xiong, Qingqing; Shi, Sanjun; Li, Zhongjun; Tao, Wei; Zhang, Han*; Mei, Lin*; Shi, Jinjun*; A Novel Top‐Down Synthesis of Ultrathin 2D Boron Nanosheets for Multimodal Imaging‐Guided Cancer Therapy, Advanced Materials, 2018, 30(36): 1803031.
(20) Ji, Xiaoyuan; Wang, Jie; Mei, Lin; Tao, Wei; Barrett, Austin; Su, Zhiguo; Wang, Shaomin; Ma, Guanghui; Shi, Jinjun*; Zhang, Songping*; Porphyrin/SiO2/Cp*Rh(bpy)Cl Hybrid Nanoparticles Mimicking Chloroplast with Enhanced Electronic Energy Transfer for Biocatalyzed Artificial Photosynthesis, Advanced Functional Materials, 2018, 28(9): 1705083.
(21) Ji, Xiaoyuan; Wang, Jie; Kang, Yong; Mei, Lin; Su, Zhiguo; Wang, Shaomin; Ma, Guanghui; Shi, Jinjun*; Zhang, Songping*; Enhanced Solar Energy Harvest and Electron Transfer through Intra- and Intermolecular Dual Channels in Chlorosome-Mimicking Supramolecular Self-Assemblies, ACS Catalysis, 2018, 8(11): 10732-10745.
(22) Tao, Wei#; Ji, Xiaoyuan#; Zhu, Xianbing; Li, Li; Wang, Junqing; Zhang, Ye; Saw, Phei Er; Li, Wenliang; Kong, Na; Islam, Mohammad Ariful; Gan, Tian; Zeng, Xiaowei; Zhang, Han; Mahmoudi, Morteza; Tearney, Guillermo J.; Farokhzad, Omid C.*; Two‐Dimensional Antimonene‐Based Photonic Nanomedicine for Cancer Theranostics, Advanced Materials, 2018, 30(38): 1802061.
(23) Zhu, Xianbing#;Ji, Xiaoyuan#; Kong, Na#; Chen, Yunhan#; Mahmoudi, Morteza; Xu, Xiaoding; Ding, Li; Tao, Wei*; Cai, Ting; Li, Yujing; Gan, Tian; Barrett, Austin; Bharwani, Zameer; Chen, Hongbo; Farokhzad, Omid C.*; Intracellular Mechanistic Understanding of 2D MoS2 Nanosheets for Anti-Exocytosis-Enhanced Synergistic Cancer Therapy, ACS Nano, 2018, 12(3): 2922-2938.
(24) Ji, Xiaoyuan; Liu, Cuicui; Wang, Jie; Su, Zhiguo; Ma, Guanghui; Zhang, Songping*; Integration of functionalized two-dimensional TaS2 nanosheets and an electron mediator for more efficient biocatalyzed artificial photosynthesis, Journal of Materials Chemistry A, 2017, 5(11): 5511-5522.
(25) Tao, Wei#; Ji, Xiaoyuan#; Xu, Xiaoding; Islam, Mohammad Ariful; Li, Zhongjun; Chen, Si; Saw, Phei Er; Zhang, Han*; Bharwani, Zameer; Guo, Zilei; Shi, Jinjun*; Farokhzad, Omid C.*; Antimonene Quantum Dots: Synthesis and Application as Near‐Infrared Photothermal Agents for Effective Cancer Therapy, Angewandte Chemie International Edition, 2017, 56(39): 11896-11900.
(26) Liu, Yanlan#; Ji, Xiaoyuan#; Liu, Jianhua; Tong, Winnie W. L.; Askhatova, Diana; Shi, Jinjun*; Tantalum Sulfide Nanosheets as a Theranostic Nanoplatform for Computed Tomography Imaging‐Guided Combinatorial Chemo‐Photothermal Therapy, Advanced Functional Materials, 2017, 27(39): 1703261.
(27) Ji, Xiaoyuan; Su, Zhiguo; Wang, Ping; Ma, Guanghui; Zhang, Songping*; Integration of Artificial Photosynthesis System for Enhanced Electronic Energy‐Transfer Efficacy: A Case Study for Solar‐Energy Driven Bioconversion of Carbon Dioxide to Methanol, Small, 2016, 12(34): 4753-4762.
(28) Ji, Xiaoyuan; Su, Zhiguo; Wang, Ping; Ma, Guanghui; Zhang, Songping*; Tethering of Nicotinamide Adenine Dinucleotide Inside Hollow Nanofibers for High-Yield Synthesis of Methanol from Carbon Dioxide Catalyzed by Coencapsulated Multienzymes, ACS Nano, 2015, 9(4): 4600-4610.
(29) Ji, Xiaoyuan; Su, Zhiguo; Wang, Ping; Ma, Guanghui; Zhang, Songping*; Polyelectrolyte Doped Hollow Nanofibers for Positional Assembly of Bienzyme System for Cascade Reaction at O/W Interface, ACS Catalysis, 2014, 4(12): 4548-4559.
獲獎情況
(1) 2021，國家優青
(2) 2020，華夏醫學科技獎
(3) 2020，天津市海河英才計畫
(4) 2020，天津大學北洋英才計畫
(5) 2017，中國教育部國家獎學金
(6) 2017，中國科學院地奧獎學金
(7) 2016，中國科學院地奧獎學金
(8) 2016，中國科學院過程工程研究所所長獎
(9) 2015，中國教育部國家獎學金
(10) 2015，國家留學基金委留學基金
(11) 2015，中國科學院過程工程研究所所長獎
(12) 2014，中國科學院過程工程研究所所長獎
(13) 2010，省級優秀畢業生
社會學術兼職
(1) 中國生物醫學工程學會會員
(2) 中國微米納米技術學會會員
(3) 國家自然科學基金委員會會評/函評專家
(4) 科技部重點研發計畫會評/函評專家
(5) 廣東省/河南省/天津市等多省市科技廳會評/函評專家
(6) 杭州師範大學“錢塘學者”特聘教授（兼）
(7) 臨沂大學高層次特聘教授（兼）
(8) Frontiers in Materials、Current Pharmaceutical Design等雜誌客座主編
(9) The Innovation、Exploration、Chinese Chemical Letters等學術期刊編委
(10) 審稿人：Nature Communications、Science Advances, Advanced Materials, Angewandte Chemie International Edition, ACS Nano, Advanced Functional Materials, Advanced Science, Small, Biomaterials等.
