夏之寧

夏之寧

夏之寧,男,重慶大學化學化工學院教授、博士生導師,重慶大學校長助理,1995年畢業於丹麥哥本哈根大學,獲博士學位。教育部“跨世紀優秀人才”,教育部“高等學校青年教師獎”,國務院政府特殊津貼獲得者。中國色譜學會理事,重慶市分析化學學科學術帶頭人,重慶市色譜學會理事長,重慶市分析測試學會副理事長。《色譜》、《環境化學》等雜誌編委。

先後主持科技部國際科技合作項目、科技部國家基礎研究規劃項目(973計畫)、國家自然科學基金項目、教育部“高校骨幹教師基金”項目以及重慶市重點項目20餘項;在SCI收錄期刊上發表論文100餘篇,出版專著2本,教材3本,獲8項專利。

基本介紹

  • 中文名:夏之寧
  • 畢業院校:丹麥哥本哈根大學
  • 學位/學歷:博士
  • 專業方向:活性天然產物等
  • 職務:重慶大學校長助理
研究方向,學術成果,

研究方向

1、活性天然產物:創新方法篩選中藥中的活性成分;改進及套用現代製備技術從中藥中獲得活性單體成分;活性成分的分子、細胞及動物水平評價。
2、藥物分析化學:手性分離分析方法研究;藥物親和分析;功能化毛細管電泳分析方法的建立及套用。
3、微波化學與波譜:微波化學反應的機理、微波熱與非熱作用、微波在有機化學、分析化學、材料化學中的套用。

學術成果

[1]Q.F.Fu,F.Q.Yang,H.Chen,Z.N.Xia,Enhancementofenantioselectivityinchiralcapillaryelectrophoresisusinghydroxypropyl-beta-cyclodextrinaschiralselectorundermolecularcrowdingconditionsinducedbydextranordextrin.Electrophoresis,2014,35(20):2938-2945.
[2]F.Li,R.Liu,F.Q.Yang,W.Xiao,C.Chen,Z.N.Xia,DeterminationofthreecurcuminoidsinCurcumalongabymicroemulsionelectrokineticchromatographywithprotectiveeffectsontheanalytes,AnalyticalMethods,2014,6(8):2566-2571.
[3]Q.Gou,L.B.Favero,S.S.Bahamyirou,Z.N.Xia,W.Caminati,InteractionsbetweenCarboxylicAcidsandAldehydes:ARotationalStudyofHCOOH-CH2O.JournalofPhysicalChemistryA,2014,118(45):10738-10741.
[4]G.Feng,Q.Gou,L.Evangelisti,Z.N.Xia,W.Caminati,Conformationalequilibriaincarboxylicacidbimolecules:arotationalstudyofacrylicacid-formicacid.PhysicalChemistryChemicalPhysics,2013,15(8):2917-2922.
[5]F.Q.Yang,J.Yang,X.M.Zhang,P.Xu,Z.N.Xia,AnalysisofvolatilecomponentsinCurcumarhizomebymicroemulsionelectrokineticchromatography,JournalofChromatographicScience,2013,51(2):155-160.
[6]J.Du,Z.N.Xia,Measurementofthecatalyticactivityofgoldnanoparticlessynthesizedbyamicrowave-assistedheatingmethodthroughtime-dependentUVspectra,AnalyticalMethods,2013,5(8):1991-1995.
[7]F.Li,F.Q.Yang,Z.N.Xia,SimultaneousDeterminationofTenNucleosidesandRelatedCompoundsbyMEEKCwith[BMIM]PF6asOilPhase,Chromatographia,2013,76(15-16):1003-1011.
[8]Z.N.Xia,Y.X.Lin,L.X.Guo,F.Q.Yang,P.Xu,Y.L.Zhang,J.H.Liu,Developmentofacell-basedhigh-throughputperoxisomeproliferator-activatedreceptors(PPARs)screeningmodelanditsapplicationforevaluationoftheextractsfromRhizomaCoptis,JournalofAsianNaturalProductsResearch,2013,15(3):225-234.
[9]Z.H.Li,G.Chen,S.Qiao,R.H.Liang,C.Lan,Z.N.Xia,DesignandSynthesisofSomeNewN-PhenylanthranilicAcidsfromHighlyStericallyHinderedAnilines,SyntheticCommunications,2013,43(9):10.
[10]H.L.Zuo,F.Q.Yang,W.H.Huang,Z.N.Xia,Preparativegaschromatographyanditsapplications,JournalofChromatographicScience,2013,51(7):704-715.
[11]H.L.Zuo,S.J.Chen,D.L.Zhang,J.Zhao,F.Q.Yang,Z.N.Xia,QualityevaluationofnaturalCordycepssinensisfromdifferentcollectingplacesinChinabythecontentsofnucleosidesandheavymetals,AnalyticalMethods,2013,5(20):5450-5456.
[12]C.Chen,F.Q.Yang,H.L.Zuo,Y.L.Song,Z.N.Xia,W.Xiao,Applicationsofbiochromatographyinthescreeningofbioactivenaturalproducts,JournalofChromatographicScience,2013,51(8):780-790.
[13]L.X.Li,Z.N.Xia,F.Q.Yang,H.Chen,Y.L.Zhang,Enantioselectiveanalysisofofloxacinenantiomersbypartial-fillingcapillaryelectrophoresiswithbacteriaaschiralselectors,JournalofSeparationScience,2012,35(16):2101-2107.
[14]F.Q.Yang,R.Lv,Y.L.Zhang,andZ.N.Xia,Comparisonstudyonnucleosidesandnucleotidesinediblemushroomspeciesbycapillaryzoneelectrophoresis,AnalyticalMethods,2012,4(2):546-549.
[15]L.X.Guo,Z.N.Xia,X.Gao,F.Yin,J.H.Liu,Glucagon-likepeptide1receptorplaysacriticalroleingeniposide-regulatedinsulinsecretioninINS-1cells,ActaPharmacologicaSinica,2012,33(2):237-241.
[16]J.Du,Z.N.Xia,Interactionsofgoldnanoparticlesandlysozymebyfluorescencequenchingmethod,AnalyticalLetters,2012,45(15):2236-2245.
[17]P.Xu,Z.N.Xia,Y.X.Lin,ChemicalconstituentsfromEdgeworthiagardneri(Thymelaeaceae),BiochemicalSystematicsandEcology,2012,45:148-150.
[18]Z.T.Chen,Z.B.Zhong,Z.N.Xia,F.Q.Yang,X.J.Mu,SeparationofFluoroquinolonesbyMEKCModifiedwithHydrophobicIonicLiquidasaModifier,Chromatographia,2012,75(1-2):65-70.
[19]Z.H.Li,S.Y.Xiao,R.H.Liang,Z.N.Xia,Synthesisof2-(arylamino)nicotinicacidsinhigh-temperaturewater,ResearchonChemicalIntermediates,2012,38(7):1691-1697.
[20]H.L.Zuo,F.Q.Yang,X.M.Zhang,Z.N.Xia,Separationofcis-andtrans-AsaronefromAcorustatarinowiibyPreparativeGasChromatography,JournalofAnalyticalMethodsinChemistry,2012,2012:402081.
[21]X.J.Mu,N.N.Yu,C.S.Wang,X.B.Zou,Z.Abulimite,Z.N.Xia,EvaluationofanewsubstrateformeasurementofserumPONarylesteraseactivity,Talanta,2012,88:711-716.
[22]X.M.Jiang,Z.N.Xia,L.H.Deng,W.L.Wei,J.Chen,J.M.Xu,H.Y.Li,EvaluationofAccuracyfortheMeasurementofOctanol-WaterPartitionCoefficientbyMEEKC,Chromatographia,2012,75(7-8):347-352.
[23]Y.Wang,F.Li,F.Q.Yang,H.L.Zuo,Z.N.Xia,Simultaneousdeterminationofα-,β-andγ-asaroneinAcorustatarinowiibymicroemulsionelectrokineticchromatographywith[BMIM]PF6asoilphase,Talanta,2012,101:510-515.
[24]G.Feng,L.Evangelisti,L.B.Favero,J.U.Grabow,Z.N.Xia,W.Caminati,OntheweakO-H···halogenhydrogenbond:arotationalstudyofCH3CHClF···H2O.PhysicalChemistryChemicalPhysics,2011,13(31):14092-14096.
[25]F.Q.Yang,H.K.Wang,H.Chen,J.D.Chen,Z.N.Xia,Fractionationofvolatileconstituentsfromcurcumarhizomebypreparativegaschromatography,JournalofAutomatedMethods&ManagementinChemistry,2011,2011:942467.
[26]J.Yang,Z.N.Xia,F.Q.Yang,R.Lv,UseofRelativeMobilitytoEstimateOctanol-WaterPartitionCoefficientsofDrugsbyMicroemulsionElectrokineticChromatography,ActaChimicaSinica,2011,69(7):810-814.
[27]Z.H.Li,Z.N.Xia,G.Chen,Catalyst-freeaminationof2-chloronicotinicacidinwaterundermicrowaveirradiation,JournalofChemicalResearch,2011,(12):709-711.
[28]K.Y.Shi,Z.N.Xia,T.T.Gan,X.M.Jiang,C.Xia,Applicationsofreal-timemonitoringtechniquesinchemicalsyntheticingredients,SpectroscopyandSpectralAnalysis,2010,30(2):499-503.
[29]G.H.Chen,Z.N.Xia,Y.Lu,PredictionofCell-PenetratingPeptidesUsingbothSupportVectorMachineandLinearDiscriminantAnalysis,ActaChimicaSinica,2010,68(11):1137-1142.
[30]Z.N.Xia,J.Yang,L.X.Li,F.Q.Yang,X.M.Jiang,DeterminationofOctanol-WaterPartitionCoefficientsbyMEEKCBasedonPeak-ShiftAssay,Chromatographia,2010,72(5-6):495-501.
[31]G.H.Chen,Z.N.Xia,Y.Lu,Three-dimensionalvectorofpharmacophoreatomicinteractionanditsapplicationstostereoisomericdescription,ChemometricsandIntelligentLaboratorySystems,2010,102(2):91-99.
[32]Y.H.Zhang,Z.N.Xia,L.T.Qin,S.S.Liu,Predictionofblood-brainpartitioning:Amodelbasedonmolecularelectronegativitydistancevectordescriptors,JournalofMolecularGraphics&Modelling,2010,29(2):214-220
[33]Z.N.Xia,T.T.Gan,H.Chen,R.Lv,W.L.Wei,F.Q.Yang,Anewopentubularcapillarymicroextractionandsweepingfortheanalysisofsuperlowconcentrationofhydrophobiccompounds,JournalofSeparationScience,2010,33(20):3221-3230.
[34]J.H.Jing,G.Z.Liang,H.Mei,S.Y.Xiao,Z.N.Xia,Quantitativestructure-mobilityrelationshipstudiesofdipeptidesincapillaryzoneelectrophoresisusingthree-dimensionalholographicvectorofatomicinteractionfield,MolecularSimulation,2009,(5):263-269.
[35]Z.N.Xia,S.Long,S.Y.Xiao,X.B.Zou,A.D'Aurizio,M.Panunzio,Microwave-AssistedCarbonyl-CarbonylCouplingRouteforthePreparationofaUsefulIntermediateintheSynthesisofCarbapenems,SyntheticCommunications,2009,39(12):2151-2160.
[36]L.X.Guo,J.H.Liu,Z.N.Xia,GeniposideinhibitsCOCl2-inducedPC12cellsdeathviathemitochondrialpathway,ChineseMedicalJournal,2009,122(23):2886-2892.
[37]X.M.Jiang,Z.N.Xia,W.L.Wei,Q.Gou,DirectUVdetectionofunderivatizedaminoacidsusingcapillaryelectrophoresiswithonlinesweepingenrichment,JournalofSeparationScience,2009,32(11):1927-1933.
[38]Z.N.Xia,L.X.Li,J.Yang,C.Q.Xiong,Investigationofinteractionbetweenthedrugandcellmembranebycapillaryelectrophoresis,ScienceinChinaSeriesB-Chemistry,2009,52(12):2200-2204.

相關詞條

熱門詞條

聯絡我們