基本介紹
- 書名:基礎神經科學系列2:神經系統發育
- 出版社:科學出版社
- 頁數:532頁
- 開本:16
- 定價:75.00
- 作者:Laary Squire Darwin Berg
- 出版日期:2009年3月1日
- 語種:英語
- ISBN:7030241584, 9787030241580
- 品牌:科學出版社
基本介紹
內容簡介
作者簡介
Larry R. Squire is Distinguished Professor of Psy-chiatry, Neurosciences, and Psychology at the Univer-sity of California School of Medicine, San Diego, andResearch Career Scientist at the Veterans AffairsMedical Center, San Diego. He investigates the organi-zation and neurological foundations of memory. He isa former President of the Society for Neuroscience andis a member of the National Academy of Sciences andthe Institute of Medicine.
Darwin K. Berg is Distinguished Professor in theDivision of Biological Sciences at the University ofCalifornia, San Diego. He has been chairman of theBiology Department and currently serves as Councilorof the Society for Neuroscience and as a Board memberof the Kavli Institute for Brain and Mind. His researchis focused on the roles of nicotinic cholinergic signal-ing in the vertebrate nervous system.
Floyd Bloom is Professor Emeritus in the Molecularand Integrative Neuroscience Department (MIND) at The Scripps Research Institute. His recent awardsinclude the Sarnat Award from the Institute of Medi-cine and the Salmon Medal of the New York Academyof Medicine. He is a former President of the Society forNeuroscience and is a member of the NationalAcademy of Sciences and the Institute of Medicine. Sascha du Lac is an Investigator of the HowardHughes Medical Institute and an Associate Professorof Systems Neurobiology at the Salk Institute for Bio-logical Studies. Her research interests are in the neu-robiology of resilience and learning, and her laboratoryinvestigates behavioral, circuit, cellular, and molecularmechanisms in the sense of balance.
Anirvan Ghosh is Stephen Kuffler Professor in theDivision of Biological Sciences at the University of California, San Diego and Director of the graduateprogram in Neurosciences. His research interestsinclude the development of synaptic connections inthe central nervous system and the role of activity-dependent gene expression in the cortical develop-ment. He is recipient of the Presidential Early CareerAward for Scientists and Engineers and the Society forNeuroscience Young Investigator Award.
Nicholas C. Spitzer is Distinguished Professor inthe Division of Biological Sciences at the University of California, San Diego. His research is focusedon neuronal differentiation and the role of electricalactivity and calcium signaling in the assembly ofthe nervous system. He has been chairman ofthe Biology Department and the Neurobiology Section,a trustee of the Grass Foundation, and served as Councilor of the Society for Neuroscience. He is amember of the American Academy of Arts and Sci-ences and Co-Director of the Kavli Institute for Brainand Mind.
圖書目錄
作者簡介
第一部分 神經科學總論
第1章 神經科學基礎
第2章 神經系統概述
第二部分 細胞和分子神經科學
第3章 神經組織的細胞元件
第4章 神經系統的亞細胞結構:細胞器及其功能
第5章 軸突和樹突的電緊張特性
第6章 跨膜電位和動作電位
第7章 神經遞質
第8章 神經遞質釋放
第9章 神經遞質受體
第10章 細胞內信號
第11章 突觸後電位和突觸融合
第12章 樹突內複雜信息處理
第13章 腦能量代謝
第三部分 神經系統發育
第14章 神經誘導和模式形成
第15章 細胞決定
第16章 神經發生和遷移
第17章 生長錐和軸突導向
第18章 靶體選擇、地形圖和突觸形成
第19章 細胞程式化死亡及神經營養因子
第20章 突觸消亡
第21章 樹突發育
第22章 早期經驗和敏感期
第四部分 感覺系統
第23章 感覺系統基礎
第24章 化學感覺:味覺和嗅覺
第25章 軀體感覺系統
第26章 聽覺
第27章 視覺
第五部分 運動系統
第28章 運動系統基礎
第29章 脊髓和外周運動系統
第30章 運動的遞減控制
第31章 基底神經節
第32章 小腦
第33章 眼動
第六部分 調節系統
第34章 下丘腦:調節系統概述
第35章 自主功能的控制:自主神經系統的組織
第36章 心血管系統的神經控制
第37章 呼吸的神經控制
第38章 食物攝取及代謝
第39章 水的攝取及體液
第40章 神經內分泌系統
第41章 生理節奏
第42章 睡眠、做夢和失眠
第43章 獎勵、動機和成癮
第七部分 行為和認知神經科學
第44章 人腦進化
第45章 認知發育和衰老
第46章 物體的視覺感知
第47章 空間識別
第48章 注意
第49章 學習與記憶:基礎機制
第50章 學習與記憶:腦系統
第51章 語言和交流
第52章 前額葉皮層及腦功能執行
第53章 意識的神經科學
索引
文摘
Three tyrosine receptor kinases and trk familymembers——trkA, trkB, and trkC——transduce neuro-trophin signals. Signaling pathways used by the trkfamily members are shared with those activated bymany other growth factor receptors. Neurotrophinbinding to trk causes receptor dimerization and phos-phorylation of cytoplasmic tyrosine residues. Phos-photyrosines recruit cytosolic adaptor proteins thatcouple the activated receptor with intracellular signal-ing pathways. The biological response of the cell to aneurotrophic factor is dependent on the dynamicstatus of the pathway that can vary with recent cellhistory. Three of the best investigated signaling path-ways are PLC-y, Ras-ERK kinase, and PI-3K. NormalPCD is governed in many neurons by PI-3 kinaseactivation of the protein kinase Akt. Trophic factordeprivation can lead to the release of pro-apoptoticmechanisms that promote cell death.