喻航(北京大學助理教授)

人物履歷

2006.09-2010.05，加拿大英屬哥倫比亞大學（University of British Columbia），微生物學與免疫學，榮譽學士

2010.06-2010.12，美國蒙特利灣水族館研究所（Monterey Bay Aquarium Research Institute），科研助理

2011.09-2017.06，美國加州理工學院（California Institute of Technology），環境科學與工程，碩士/博士

2017.08-2020.02，美國加州理工學院（California Institute of Technology），博士後

2020.07-2022.06，美國南加州大學（University of Southern California），博士後

2022.12-至今，北京大學（Peking University），研究員、助理教授

科學研究

研究內容

微生物在地球生態系統中發揮著至關重要的作用。喻航老師課題組致力於解析地球生物化學循環中微生物組群的動態和功能，了解氣候變化與微生物之間的相互作用，探索並利用微生物的生化反應潛能。

研究方向

1. 溫室氣體甲烷的生物氧化

2. 金屬元素的微生物代謝

3. 微生物之間的相互作用和共生方式

研究方法

結合傳統與尖端的微生物實驗技術，如菌種培養、代謝產物分析、同位素示蹤、遺傳與進化分析、高通量測序、合成生物學、電化學、礦物結構分析、螢光與納米二次離子質譜成像等。

研究成果

發表論文

Yu, H., Speth, D.R., Connon, S.A., Goudeau, D., Malmstrom, R.R., Woyke, T., and Orphan V.J. (2022) Community structure and microbial associations in sediment-free methanotrophic enrichment cultures from a marine methane seep. Applied and Environmental Microbiology. e02109-21.
Heryakusuma, C., Susanti, D., Yu, H., Li, Z., Purwantini, E., Hettich, R.L., Orphan, V.J., and Mukhopadhyay, B. (2022) A reduced F420-dependent nitrite reductase (FNiR) in an anaerobic methanotrophic archaeon. Journal of Bacteriology. e00078-22.
Yu, H., Chadwick, G.L., Lingappa, U.F., and Leadbetter J.R. (2022) Comparative genomics on cultivated and uncultivated, freshwater and marine “Candidatus Manganitrophaceae” species implies their worldwide reach in manganese chemolithoautotrophy. mBio. 13 (2), e03421-21.
Chadwick, G. L., Skennerton, C. T., Laso-Pérez, R., Leu, A. O., Speth, D. R., Yu, H., Morgan-Lang, C., Hatzenpichler, R., Goudeau, D., & Malmstrom, R. (2022). Comparative genomics reveals electron transfer and syntrophic mechanisms differentiating methanotrophic and methanogenic archaea. Plos Biology 20 (1): e3001508.
Yu, H., Skennerton, C.T., Chadwick, G.L., Leu, A.O., Aoki, M., Tyson, G.W., and Orphan V.J. (2022) Sulfate differentially stimulates but is not respired by diverse anaerobic methanotrophic archaea. The ISME Journal 16, 168–177. （ISME Journal Editor's Choice）
Yu, H., Leadbetter, J.R. (2020) Bacterial chemolithoautotrophy via manganese oxidation. Nature 583, 453–458. (Nature Cover)
Yu, H., Susanti, D., McGlynn, S.E., Skennerton, C.T., Chourey, K., Iyer, R., Scheller, S., Tavormina, P., Hettich, R.L., Mukhopadhyay, B., and Orphan, V.J. (2018) Comparative genomics and proteomic analysis of assimilatory sulfate reduction pathways in anaerobic methanotrophic archaea. Frontiers in Microbiology. 9.
Scheller, S., Yu, H., Chadwick, G.L., McGlynn, S.E., and Orphan, V.J. (2016) Artificial electron acceptors decouple archaeal methane oxidation from sulfate reduction. Science 351: 703–707. （Featured in Science Perspective）
van Baren, M.J., Bachy, C., Reistetter, E.N., Purvine, S.O., Grimwood, J., Sudek, S., Yu, H., Poirier, C., Deerinck, T.J., Kuo, A., Grigoriev, I.V., Wong, C., Smith, R.D., Callister, S.J., Wei, C., Schmutz, J., and Worden, A.Z. (2016) Evidence-based green algal genomics reveals marine diversity and ancestral characteristics of land plants. BMC Genomics 17: 267.
Glass, J.B., Yu, H., Steele, J.A., Dawson, K.S., Sun, S., Chourey, K., Pan, C., Hettich, R.L., Orphan, V.J. (2014) Geochemical, metagenomic and metaproteomic insights into trace metal utilization by methane-oxidizing microbial consortia in sulphidic marine sediments. Environmental Microbiology 6, 1592-1611.
Hartmann, M., Howes, C.G., VanInsberghe, D., Yu, H., Bachar, D., Christen, R., Nilsson, R.H., Hallam, S.J. and Mohn, W.W. (2012) Significant and persistent impact of timber harvesting on soil microbial communities in Northern coniferous forests. The ISME Journal 6, 2199–2218.