唐達林(東南大學數學學院教授)

唐達林(東南大學數學學院教授)

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唐達林，男，博士，東南大學數學學院教授。

基本介紹

  • 中文名：唐達林
  • 學位/學歷：博士
  • 職業：教師
  • 任職院校：東南大學數學學院
個人經歷,學術成果,

個人經歷

1982年畢業於南京工學院（現東南大學）。2012聘為東南大學教授，博導。唐達林教授自1983年赴美留學，並於1988年獲得威斯康星大學麥迪遜分校套用數學博士學位，任美國伍斯特理工學院數學和生物醫學工程終身教授，其中於2003-2006 年被任命為 John E. Sinclair Professor of Mathematics。美國美國機械工程師學會Fellow, 美國心臟學會Fellow，並是美國數學學會和美國生物力學工程學會會員。目前擔任Journal of Molecular & Cellular Biomechanics 主編, PLOS ONE Academic Editor, BioMedical Engineering OnLine副主編。參加多項中國，美國及國際學術評估委員會工作 （包括美國心臟學會、美國國家科學基金會、美國國家健康基金會, 中國基金委，教育部）。 唐達林教授三十多年以來一直從事心血管疾病數學模型，臨床與基礎研究，先後發表國際期刊和學術會議論文300餘篇；共主持和參與包括美國國家健康基金會 （NIH）、美國國家科學基金會 (NSF)等30餘項研究項目，並與美國哈佛大學、麻省理工學院、華盛頓大學（Seattle）、華盛頓大學 (St. Louis)、喬治亞理工學院、日本信州大學,以及中國北京師範大學等學校有多項聯合重大研究項目。
2016-Present：PLOS One Academic Editor
2014-PresentEditor-in-Chief,Journal ofMolecular & Cellular Biomechanics
2010-PresentBioMedical Engineering OnLine, published by BioMed Central, Springer.

學術成果

Publications(Selected from over 300 journal and conference papers)
  1. Dalin Tang and M. C. Shen, “Peristaltic Transport of a Heat-Conducting Fluid Subject to Newton's Cooling Law at the Boundary,” Int. J. Eng. Scien., Vol. 27, No.7, pp. 809-825, 1989.
  2. Dalin Tang, “Numerical Solutions of Viscous Flow in Elastic Tubes with Stenoses of Various Stiffness,” Proceedings of the 1995 Bioengineering Conference, BED-Vol. 29, pp. 521-522, 1995.
  3. Dalin Tang, “Viscous Flow in Stenotic Elastic Tubes with Free Moving Boundaries, Part I: Steady Flow,” Proceedings of The BMES 1995 Annual Fall Meeting, 1995.
  4. Dalin Tang, Chun Yang, Yan Huang and D. N. Ku, “Wall Stress and Strain Analysis Using a 3-D Thick-Wall Model with Fluid-Structure Interactions for Blood Flow in Carotid Arteries with Stenoses,” Computers and Structures, Vol. 72, 341-356, 1999.
  5. Dalin Tang, Chun Yang, Shunichi Kobayashi, Jie Zheng, and Raymond P. Vito, “Effects of stenosis asymmetry on blood flow and artery compression: a 3-D FSI model,” Annals of Biomedical Engineering, 31:1182-1193, PMID: 14649492, 2003.
  6. Dalin Tang, Chun Yang, Jie Zheng, Pamela K. Woodard, G. A. Sicard, Jeffery E. Saffitz, and Chun Yuan, “MRI-Based 3D flow and stress analysis of vulnerable plaques,” Proceedings of NIH Symposium: Digital Biology: The Emerging Paradigm, p. 91, 2003.
  7. Dalin Tang, Chun Yang, Shunichi Kobayashi, David N. Ku, “Effect of a Lipid Pool on Stress/Strain Distributions in Stenotic Arteries: 3D FSI Models,” J. Biomechanical Engineering, Vol. 126, 363-370, PMID: 15341174, June 2004.
  8. Dalin Tang, Chun Yang, Jie Zheng, Pamela K. Woodard, Gregorio A. Sicard, Jeffrey E. Saffitz, and Chun Yuan, 3D MRI-Based Multi-Component FSI Models for Atherosclerotic Plaques, a 3-D FSI model, Annals of Biomedical Engineering, July 2004,Vol. 32, No. 7, pp. 947-960, PMID: 15298432, (Selected in Best Paper Selection, International Medical Informatics Association (IMIA) Year Book 2006, page 70).
  9. Dalin Tang, Modeling Flow in Healthy and Stenosed Arteries,Wiley Encyclopedia of Biomedical Engineering,editor: Metin Akay, Hoboekn, John Wiley & Sons, Inc., New Jersey, Article 1525, pp. 1-16, 2006.web access: dx.doi.org/10.1002/9780471740360.ebs1525.
  10. Dalin Tang, Chun Yang, and Chun Yuan, Mechanical Image Analysis Using Finite Element Method,Carotid Disease:The Role of Imaging in Diagnosis and Management, Chief Editor, Jonathan H Gillard, co-editors, Drs. T.S. Hatsukami, M. Graves, and C. Yuan, Cambridge University Press, Cambridge, England, pp. 323-339, 2006.
  11. Chun Yang, Dalin Tang,* Idith Haber, Tal Geva, Pedro J. del Nido, In Vivo MRI-Based 3D FSI RV/LV Models for Human Right Ventricle and Patch Design for Potential Computer-Aided Surgery Optimization, Computers & Structures, 85, 988-997, 2007.
  12. Dalin Tang,Chun Yang,Sayan Mondal,Fei Liu,Gador Canton, Thomas S. Hatsukami,Chun Yuan, A Negative Correlation between Human Carotid Atherosclerotic Plaque Progression and Plaque Wall Stress: In Vivo MRI-Based 2D/3D FSI Models, J. Biomechanics,41(4):727-736, PMID:18191138, PMCID: PMC2291514, DOI information: 10.1016/j.jbiomech.2007.11.026, 2008, Featured article by the Society for Heart Attack Prevention and Eradication (SHAPE), March 2008, http://www.shapesociety.org.
  13. Chun Yang,Richard Bach,Jie Zheng, Issam El Naqa, Pamela K Woodard,Zhongzhao Teng, Kristen Billiar,Dalin Tang,In Vivo IVUS-Based 3D Fluid Structure Interaction Models with Cyclic Bending and Anisotropic Vessel Properties for Human AtheroscleroticCoronary Plaque Mechanical Analysis, IEEE Transactions on Biomedical Engineering, 2009 Oct;56(10):2420-8. Epub 2009 Jun 26.PMID: 19567341. PMCID: PMC2918807.
  14. Dalin Tang,Zhongzhao Teng, Gador Canton, Chun Yang, Marina Ferguson, Xueying Huang,Jie Zheng, Pamela K Woodard, Chun Yuan, Sites of Rupture in Human Atherosclerotic Carotid Plaques are Associated with High Structural Stresses: an In Vivo MRI-Based 3D Fluid-Structure Interaction Study,AHA Journal, Stroke. 2009.;40;3258-3263; online July 23, 2009,DOI: 10.1161/STROKEAHA.109.558676.Featured article on MDlinx.com.PMID: 19628799, . PMCID: PMC2753753.
  15. Dalin Tang, Zhongzhao Teng, Gador Canton, Thomas S. Hatsukami,Li Dong,Xueying Huang,Chun Yuan , Local Critical Stress Correlates Better than Global Maximum Stress with Plaque Morphological Features Linked to Atherosclerotic Plaque Vulnerability: AnIn VivoMulti-Patient Study, BioMedical Engineering OnLine 2009, 8:15 doi:10.1186/1475-925X-8-15, PMID: 19650901,PMCID: PMC2727515
  16. Zhongzhao Teng,Gador Canton,Chun Yuan,Marina Ferguson, Chun Yang,Xueying HuangJie Zheng, Pamela K Woodard, Dalin Tang,3D Critical Plaque Wall Stress Is a Better Predictor of Carotid Plaque Rupture Sitesthan Flow Shear Stress: An In Vivo MRI-Based 3D FSI Study,J. of Biomechanical Engineering,132(3):031007,March 2010. PMID: 20459195.PMCID: PMC2924579.
  17. Zhongzhao Teng,Gador Canton,Chun Yuan,Marina Ferguson, Chun Yang, Xueying Huang,Jie Zheng, Pamela K Woodard,Dalin Tang, Three-Dimensional Critical Plaque Wall Stress Is a Better Predictor of Carotid Plaque Ulcerated Site of Rupture than Critical Flow Shear Stress: An In Vivo MRI-Based 3D FSI Study, Arteriosclerosis, Thrombosis and Vascular Biology Annual Conference, poster, 2010.
  18. Chun Yang, Chun Yuan, Gador Canton, Thomas Hatsukami, Dalin Tang, Advanced Human Carotid Plaque Progression Correlates Positively with Flow Shear Stress: An In Vivo MRI Multi-Patient 3D FSI Study, Arteriosclerosis, Thrombosis and Vascular Biology,30;e315,2010.
  19. Dalin Tang, Chun Yang,Jie Zheng, Gador Canton, Richard Bach, Thomas S. Hatsukami,Liang Wang,Kristen L. Billiar, and Chun Yuan, Image-Based Modeling and Precision Medicine: Patient-Specific Carotid and Coronary Plaque Assessment and Predictions, IEEE Transactions on Biomedical Engineering.2013. Mar;60(3):643-51. doi: 10.1109/TBME.2013.2242891. Epub 2013 Jan 25. PMID: 23362245
  20. Tang D, Yang C, Geva T, Del Nido PJ. Right ventricular local longitudinal curvature as a marker and predictor for pulmonary valve replacement surgery outcome: An initial study based on preoperative and postoperative cardiac magnetic resonance data from patients with repaired tetralogy of Fallot. J Thorac Cardiovasc Surg. 2014 Jan;147(1):537-8. doi: 10.1016/j.jtcvs.2013.08.054. Epub 2013 Oct 5. 2013 Oct 4. PMID: 24100105. NIHMS523022.
  21. Dalin Tang, Roger D. Kamm, Chun Yang,Jie Zheng,Gador Canton,Richard Bach,Xueying Huang, Thomas S. Hatsukami,Jian Zhu, Genshan Ma, Akiko Maehara, Gary Mintz, and Chun Yuan, Image-Based Modeling for Better Understanding and Assessment of Atherosclerotic Plaque Progression and Vulnerability: Data, Modeling, Validation, Uncertainty and Predictions, J Biomechanics, 47:834-846, 2014. NIHMSID 557178; http://authors.elsevier.com/offprints/BM6477/3ab9d898c0217e5158dcb66145a76c4c
  22. Liang Wang, Zheyang Wu, Chun Yang,Jie Zheng, Richard Bach, David Muccigrosso, Kristen Billiar,Akiko Maehara, Gary S. Mintz, Dalin Tang, IVUS-Based FSI Models for Human Coronary Plaque Progression Study: Components, Correlation and Predictive Analysis, Annals of Biomedical Engineering, 2015;43(1):107-121.NIHMS 630346.
  23. Dalin Tang,Zhi-Yong Li, Frank Gijsen,Don P Giddens, Cardiovascular Diseases and Vulnerable Plaques: Data, Modeling, Predictions and Clinical Applications, BioMedical Engineering OnLine, 2015 Jan 9;14(Suppl 1):S1.
  24. Liang Wang, Akiko Meahara, Chun Yang, Jie Zheng, Richard Bach, David Muccigrosso, Gary S. Mintz, Dalin Tang,IVUS-Based Fluid-Structure Interaction Models for Novel Plaque Vulnerability Indices: A Study in Patients with Coronary Artery Disease, Procedia Engineering 126 ( 2015 ) 436 – 440
  25. Xiaoya Guo, Jian Zhu, Akiko Maehara, David Molony, Habib Samady, Liang Wang, Kristen L. Billiar,Jie Zheng, Chun Yang, Gary S. Mintz, Don P Giddens, Dalin Tang,Quantify Patient-Specific Coronary Material Property and Its Impact on Stress/Strain Calculations Using In Vivo IVUS Data and 3D FSI Models: a Pilot Study,Biomechanics and Modeling in Mechanobiology. 2017;16(1), 333-344.2016.Aug 25.[Epub ahead of print] PMID: 27561649 NIHMSID 813075
  26. Liang Wang, Jian Zhu, Habib Samady, David Monoly, Jie Zheng, Xiaoya Guo, Akiko Maehara, Chun Yang, Genshan Ma,Gary S. Mintz, Dalin Tang, Effects of Residual Stress, Axial Stretch and Circumferential Shrinkage on Coronary Plaque Stress and Strain Calculations: an In Vivo IVUS-Based Modeling Study, Journal of Biomechanical Engineering. 2017 Jan 1;139(1). doi: 10.1115/1.4034867.
  27. Dalin Tang, Chun Yang,Sarayu Huang,Venkatesh Mani,Jie Zheng, Pamela K Woodard, Philip Robson, Zhongzhao Teng, Marc Dweck,Zahi A. Fayad, Cap Inflammation Leads to Higher Plaque Cap Strain and Lower Cap Stress: An MRI-PET/CT-Based FSI Modeling Approach, J. of Biomechanics.2017 Jan 4;50:121-129. doi: 10.1016/j.jbiomech.2016.11.011.Epub 2016 Nov 11.NIH 829504.
  28. Dalin Tang, Zhi‑Yong Li, Preface: Computational and experimental methods for biological research: cardiovascular diseases and beyond, BioMed Eng OnLine 2016, 15(Suppl 2):157. DOI 10.1186/s12938-016-0269-8.
  29. Guo X, Giddens DP, Molony D, Yang C, Samady H, Zheng J, Mintz G, Maehara A, Wang L, Pei X, Li ZY, Tang D. An FSI Modeling Approach to Combine IVUS and OCT for More Accurate Patient-Specific Coronary Morphology and Stress/Strain Calculations, J Biomech Eng. 2018 Apr 1;140(4). doi: 10.1115/1.4038263. 2017 Oct 23.[Epub ahead of print]
  30. Xiaoya Guo, David Molony, Chun Yang, Habib Samady, Jie Zheng, Liang Wang, Gary S. Mintz, Akiko Maehara, Xuan Pei, Zhi-Yong Li, Dalin Tang*, Don P. Giddens, Patient-Specific Coronary Models Combining Intravascular Ultrasound and Optical Coherence Tomography Lead to More Accurate Plaque Cap Thickness and Stress/Strain Quantifications, Arterioscler Thromb Vasc Biol. 2017;37:A383.http://atvb.ahajournals.org/content/37/Suppl_1/A383, ATVB|PVD 2017 Scientific Sessions, May 4 – 6, 2017.Minneapolis,
  31. Wang L, Tang D, Maehara A, Wu Z, Yang C, Muccigrosso D, Zheng J, Bach R, Billiar KL, Mintz GS.Fluid-structure interaction models based on patient-specific IVUS at baseline and follow-up for prediction of coronary plaque progression by morphological and biomechanical factors: A preliminary study, J Biomech. 2018 Feb 8;68:43-50. doi: 10.1016/j.jbiomech.2017.12.007. Epub 2017 Dec 15.
  32. Jian Guo, Liang Wang, David Molony, Habib Samady, Jie Zheng, Xiaoya Guo, Akiko Maehara, Gary S. Mintz, Jian Zhu, Genshan Ma, Dalin Tang,In Vivo Intravascular Ultrasound-Based 3D Thin-Walled Model for Human Coronary Plaque Progression Study: Transforming Research to Potential Commercialization, Int’l J. Computational Methods, Accepted.
  33. Xiaoya Guo, Dalin Tang, David Molony, Chun Yang, Habib Samady, Jie Zheng, Gary S. Mintz, Akiko Maehara, Liang Wang, Xuan Pei, Zhi-Yong Li, Genshan Ma, Don P. Giddens, A machine learning-based method for intracoronary OCT segmentation andvulnerable coronary plaque cap thickness quantification,Accepted to: Int’l J. Computational Methods.
  34. Deng L, Huang X, Yang C, Lyu B, Duan F, Tang D, Song Y. Numerical simulation study on systolic anterior motion of the mitral valve in hypertrophic obstructive cardiomyopathy, Int J Cardiol. 2018 Sep 1;266:167-173. doi: 10.1016/j.ijcard.2018.01.062.
  35. Deng L, Huang X, Yang C, Song Y, Tang D.Patient-specific CT-based 3D passive FSI model for left ventricle in hypertrophic obstructive cardiomyopathy. Comput Methods Biomech Biomed Engin. 2018 Feb 21:1-9. doi: 10.1080/10255842.2018.1443215. [Epub ahead of print]
  36. Xiaoya Guo, Dalin Tang,* David Molony,Chun Yang, Habib Samady, Jie Zheng, Gary S. Mintz, Akiko Maehara, Jian Zhu, Genshan Ma, Don P. Giddens, Predicting Plaque Area Increase and Plaque Burden Increase Using Patient-Specific Fluid-Structure-Interaction Models Based on IVUS and OCT Images with Follow-Up, The 9th International Conference on Computational Methods (ICCM2018), full paper, accepted.
  37. Dalin Tang, Xiaoya Guo, Longling Fan, Zhi-Yong Li, Biomechanical Study and Patient-Specific Models for Vulnerable Plaques, Book Chapter for “Patient-Specific Biomechanical Models and Applications,” Editors, Yubo Fan and Xiaoyan Deng, 2018. National Publication Foundation.Shanghai Jiaotong University Press.
近期項目
1.國家自然科學基金面上項目，11672001，仿真流固耦合心臟計算模型在虛擬手術、手術方案最佳化及療效預測中的套用，2017/01-2020/12，62萬元，在研，主持。
2.國家自然科學基金面上項目，81571691，基於心臟超聲的左心室流固耦合仿真力學模型在起搏器方案最佳化中的套用，2016/01-2019/12，66萬元，在研，第一參與人（主持：南京醫科大學，姚靜）。
3.江蘇省重點研發計畫項目，BE2016785，冠心病臨界病變的規範化診療。2016.7-2019.6. 195萬元，東南大學配套200萬元，負責內容：第一參與人，負責數學模型。（主持人，馬根山，中大醫院心內科主任）。
4.美國NIH/NHLBI, R01 HL089269,3D MRI-Based Modeling for Computer-Aided Right Ventricle Remodeling Surgery,06/01/2009-05/31/2016, $2,070,684, Multiple PI: Pedro del Nido, Tal Geva (Harvard Medical School); Dalin Tang, WPI.已結題，並列主持.
5.美國NIH/NIBIB,2R01EB004759, In Vivo IVUS Image-Based Modeling for Human Coronary Plaque Assessment 09/2004-11/30/2015，$2,483,120,已結題，主持。
6.美國NSF/NIH-NIGMS DMS-0540684，Multi-Physics Modeling and Meshless Methods for Atherosclerotic Plaque Progression (03/15/06-02/28/12)$1,847,537.已結題，主持。
7.美國Massachusetts Technology Transfer Center (MTTC)(07/01/05-07/31/06)，Image-Based Computational Mechanical Analysis and Indexing for Cardiovascular Diseases，Amount:$5,000 awarded（專利技術市場調研）.已結題，主持。
8.美國凱樂琳發明獎，Kalenian Award,專利產業化獎，Worcester Polytechnic Institute, 2008 (6/2008-12/2009). Image-Based Computational Mechanical Analysis and Indexing for Cardiovascular Diseases, From Invention to Commercialization，Amount:$25000 + $5000 Legal Services, Awarded.已結題，主持。
榮譽（Honors, Awards, and Recognition）
1982:First Place in the National Graduate Entrance Exam to the Applied Math
Graduate Program at NIT, Received $50,000 Scholarship to study in US.
1993:WPI President MQP Advisor Award.
2003-2006:John E. Sinclair Professor of Mathematics, WPI.
2003:Featured article by Association of Eradication of Heart Attack , Liu SQ,
Tang D, Tieche C, and Alkema P, “Pattern formation of vascular smooth
muscle cells subject to nonuniform fluid shear stress,”Am. J. Physio. Heart Circ Physiol,285(3):H1072-80, PMID: 12730056, 2003.
2004:First NIH R01 award received.
2005:Massachusetts Technology Transfer Center (MTTC) Award.
2006:Best Paper Selection, International Medical Informatics Association (IMIA) Year Book 2006:Tang, Yang, Zheng, Woodard, Sicard, Saffitz, and Yuan, 3D MRI-Based Multi-Component FSI Models for Atherosclerotic Plaques, a 3-D FSI model, Annals of Biomedical Engineering, 32(7): 947-960, 2004.
2006:Invited paper for an authoritative Encyclopedia:Modeling Flow in Healthy and Stenosed Arteries, Wiley Encyclopedia of Biomedical Engineering,
2007:Best paper award, 2007 IEEE/ICMEInternational Conference on Complex Medical Engineering, Dalin Tang, Chun Yang, Tal Geva, Pedro J. del Nido, Patient-Specific Virtual Surgery for Right Ventricle Volume Reduction and Patch Design Using MRI-Based 3D FSI RV/LV/Patch Models, pp. 158-163,2007.
2007:Honorable Mentioning,Sayan Mondel, Chun Yang, Joseph D. Petruccelli, Chun Yuan, Fei Liu, Tom Hatsukami, Dalin Tang, A New Hypothesis for Human Atherosclerotic Plaque Progression Based on Serial In Vivo MRI and Computational Modeling Method, Proceedings of the ASME 2007 Summer Bioengineering Conference, ASME 2007 Summer Bioengineering Conference UndergraduateStudent paper competition
2007:WPI 2007 Summer Undergraduate Research Fellowships
Student: Sayan Mondal; Advisor: Dalin Tang
Computational modeling and methods for diseased arteries
2007:Research presentation to United States Congress representatives on Capitol Hill at the annual Coalition for National Science Funding (CNSF) exhibition, representingAmerican Mathematical Society.
2008:Featured article of the month (Feb 2008) by the Society for Heart Attack
Prevention and Eradication, Tang, Yang, Mondal, Liu, Canton, Hatsukami,Yuan, A Negative Correlation between Human Carotid Atherosclerotic Plaque Progression and Plaque Wall Stress: In Vivo MRI-Based 2D/3D FSI Models, J. Biomechanics,Vol 41/4 pp 727-736.
2008:Two invited presentations at NIH-sponsored NHLBI-VCU Workshop for
MDs, physicians, and engineers on Computational Cardiovascular and
Cardiopulmonary Dynamics,(1) MRI-based Atherosclerotic Plaques
Assessment and Rupture Predictions;(2) Patient-Specific RV/LV/Patch
Models for Ventricle Surgery Optimization,Feb., 2008.
2008:Kalenian Award, Worcester Polytechnic Institute, 2008.
2009:Second NIH R01 award received.MRI-Based Ventricle modeling.
2010:Third NIH R01 award received.
IVUS-Based Modeling for coronary plaque
2009:Featured article by MDLinx.com, Tang et al., Sites of Rupture in Human Atherosclerotic Carotid Plaques are Associated with High Structural Stresses: an In Vivo MRI-Based 3D Fluid-Structure Interaction Study,AHA Journal, Stroke. 2009.;40;3258-3263.
2010:NIH/NIBIB Website Featuring our research: E- Advance - Modeling Mechanical Stress in Vulnerable Plaques to Reduce Strokes, http://www.nibib.nih.gov/HealthEdu/eAdvances/26Feb10.
2010:WPI Trustee’s award for Outstanding Research and Creative Scholarship
http://www.wpi.edu/news/20090/convocation2010.html
2011: Elected Fellow, American Heart Association
2013:Featured Article on ASME Journal of Biomechanical Engineering.
2014:ASME Certificate of Appreciation of Outstanding Service to Journal of
Biomechanical Engineering as an Associate Editor,
2015:Elected Fellow, ICCES.
2016:Elected Fellow, ASME (American Society of Mechanical Engineers)
2016:Member, US National Academy of Inventers.
2017: Best Paper award, International Conference of Computational Methods, Xiaoya Guo, Dalin Tang, David Molony, Chun Yang, Habib Samady, Jie Zheng, Gary S. Mintz, Akiko Maehara, Liang Wang, Xuan Pei, Zhi-Yong Li, Genshan Ma, Don P. Giddens, A machine learning-based method for intracoronary OCT segmentation andvulnerable coronary plaque cap thickness quantification, July 2017.
2018:Highlighted Article on Journal of Biomechanics, Feb 2018: Liang Wang, Dalin Tang*, Akiko Maehara, Zheyang Wu, Chun Yang, David Muccigrosso, Jie Zheng, Richard Bach, Kristen L. Billiar, Gary S. Mintz, Fluid-Structure Interaction Models Based on Patient-Specific IVUS at Baseline and Follow-Up for Prediction of Coronary Plaque Progression by Morphological and Biomechanical Factors: A Preliminary Study. 2018 Feb 8;68:43-50. doi: 10.1016/j.jbiomech.2017.12.007. Epub 2017 Dec 15.

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