科研成果
作為《急性胰腺炎中西醫結合診療共識意見》《慢性胰腺炎中西醫結合診療共識意見》執筆人,以個人或團隊獲15項急性胰腺炎相關的國家自然科學基金項目;提出“方劑組織藥理學”新假說,發表論文70餘篇,SCI收錄50餘篇。
著作譯作
《中西醫結合實驗醫學》副主編
學術任職
教育部科技獎勵評審專家;國家自然科學基金同行評議專家;WJG.eCAM等3個SCI雜誌編委;中國民族醫藥學會脾胃病分會副會長兼胰腺炎專家委員會主任委員;中國中西醫結合消化學會急性胰腺炎專家委員會主任委員;中國醫促會中西醫結合消化分會常委兼胰腺疾病學組組長;世中聯消化病分會常務理事;四川省中醫藥學會腎臟病專委會名譽主任委員;遼寧省中醫藥學會熱病專委會名譽副主任委員;四川省中西醫結合學會消化內科專業委員會主任委員。
擅長領域
1. 中西匯通治療急性胰腺炎、慢性胰腺炎、胰腺假性囊腫、黃疸、膽囊炎、膽結石、不全性腸梗阻;
2. 中西醫結合治療口苦口臭、飲食異常、食管炎、胃腸炎、胃十二指腸潰瘍、慢性腹瀉、消化不良、肥胖、慢性腹痛、便秘;
3. 怕風怕冷、多汗、夜尿頻繁、失眠多夢、煩躁易怒、痤瘡、黃褐斑、肥胖、高血脂、脂肪肝、高血壓、糖尿病、中風后遺症/腦梗塞的中醫藥治療;
4.胰腺癌、胃癌、肝癌等各種癌腫的中醫治療;
5. 痛經、月經不調、白帶異常、不需手術的乳腺炎/乳腺結節/甲狀腺結節、各種疑難雜症的平脈辯證治療;產後/術後調理、亞健康調理。
部分論文
1) Yao J, Miao Y, Zhu L, Wan M, Lu Y, Tang W. Histidine triad nucleotide-binding protein 2: From basic science to clinical implications. Biochem Pharmacol. 2023 Jun;212:115527. doi: 10.1016/j.bcp.2023.115527. Epub 2023 Mar 31. PMID: 37004779.
2) Yao J, Miao Y, Zhang Y, Zhu L, Chen H, Wu X, Yang Y, Dai X, Hu Q, Wan M, Tang WF*. Dao-Chi Powder Ameliorates Pancreatitis-Induced Intestinal and Cardiac Injuries via Regulating the Nrf2-HO-1-HMGB1 Signaling Pathway in Rats. Front Pharmacol. 2022 Jul 11;13:922130
3) Wu X, Yao J, Hu Q, Kang H, Miao Y, Zhu L, Li C, Zhao X, Li J, Wan M, Tang WF*. Emodin Ameliorates Acute Pancreatitis-Associated Lung Injury Through Inhibiting the Alveolar Macrophages Pyroptosis. Front Pharmacol. 2022 Jun 2;13:873053.
4) Dai XY, Hu Q, Yao JQ, Wu XJ, Miao YF, Li J, Wan MH, Tang WF*. Zengye Decoction Attenuated Severe Acute Pancreatitis Complicated with Acute Kidney Injury by Modulating the Gut Microbiome and Serum Amino Acid Metabolome. Evid Based Complement Alternat Med. 2022 May 9;2022:1588786.
5) Qian Hu, Jiaqi Yao, Xiajia Wu, Juan Li, Guixiang Li, Wenfu Tang*, Jingping Liu*, Meihua Wan*.Emodin attenuates severe acute pancreatitis-associated acute lung injury by suppressing pancreatic exosome-mediated alveolar macrophage activation, Acta Pharmaceutica Sinica B,Oct;12(10):3986-4003.
6) Zhao X, Zhu S, Li J, Long D, Wan M, Tang WF*. Epigenetic changes in inflammatory genes and the protective effect of cooked rhubarb on pancreatic tissue of rats with chronic alcohol exposure. Biomed Pharmacother. 2022 Feb;146:112587
7) Lv JQ, Li PC, Zhou L, Tang WF*, Li N*. Acupuncture at the P6 Acupoint to Prevent Postoperative Pain after Craniotomy: A Randomized, Placebo-Controlled Study. Evid Based Complement Alternat Med. 2021 Mar 17;2021:6619855.
8) Hu J, Zhang YM, Miao YF, Zhu L, Yi XL, Chen H, Yang XJ, Wan MH, Tang WF*. Effects of Yue-Bi-Tang on water metabolism in severe acute pancreatitis rats with acute lung-kidney injury. World J Gastroenterol. 2020 Nov 21;26(43):6810-6821
9) Li J, Hu Q, Xiao-Yu D, Zhu L, Miao YF, Kang HX, Zhao XL, Yao JQ, Long D, Tang WF, Wan MH*. Effect of Sheng-Jiang Powder on Gut Microbiota in High-Fat Diet-Induced NAFLD. Evid Based Complement Alternat Med. 2020 Nov 26;2020:6697638
10) Yi XL, Hu J, Wu QT, Zhang YM, Hu Q, Yuan L, Miao YF, Chen H, Zhu L, Li J, Zhao XL, Yao JQ, Dai XY, Wan MH, Tang WF*. Effect of Different-Volume Fluid Resuscitation on Organ Functions in Severe Acute Pancreatitis and Therapeutic Effect of Poria cocos. Evid Based Complement Alternat Med. 2020 Oct 14;2020:6408202
11) Yao JQ, Zhu L, Miao YF, Zhu L, Chen H, Yuan L, Hu J, Yi XL, Wu QT, Yang XJ, Wan MH, Tang WF*. Optimal dosing time of Dachengqi decoction for protection of extrapancreatic organs in rats with experimental acute pancreatitis. World J Gastroenterol. 2020 Jun 14;26(22):3056-3075
12) Miao YF, Kang HX, Li J, Zhang YM, Ren HY, Zhu L, Chen H, Yuan L, Su H, Wan MH, Tang WF*. Effect of Sheng-jiang powder on multiple-organ inflammatory injury in acute pancreatitis in rats fed a high-fat diet. World J Gastroenterol. 2019. 25(6): 683-695.5.742
13) Miao YF, Li J, Zhang YM, Zhu L, Chen H, Yuan L, Hu J, Yi XL, Wu QT, Wan MH, Tang WF*. Sheng-jiang powder ameliorates obesity-induced pancreatic inflammatory injury via stimulating activation of the AMPK signalling pathway in rats. World J Gastroenterol. 2018. 24(39): 4448-4461.
14) Li J, Zhu L, Zhang YM, Chen H, Miao YF, Kang HX, Ren HY, Wan MH, Long D, Tang WF* Sheng-Jiang Powder Ameliorates High Fat Diet Induced Nonalcoholic Fatty Liver Disease via Inhibiting Activation of Akt/mTOR/S6 Pathway in Rats. Evid Based Complement Alternat Med. 2018. 2018: 6190254.
15) Yuan L, Zhu L, Zhang Y, Chen H, Kang H, Li J, Zhao X, Wan M, Miao Y, Tang W*. Effect of Da-Cheng-Qi decoction for treatment of acute kidney injury in rats with severe acute pancreatitis. Chin Med. 2018. 13:38.
16) Li J, Zhang YM, Li JY, Zhu L, Kang HX, Ren HY, Chen H, Yuan L, Miao YF, Wan MH, Tang WF*.Effect of Sheng-Jiang Powder on Obesity-Induced Multiple Organ Injuries in Rats.Evid Based Complement Alternat Med. 2017;2017:6575276.
17) Zhang YM, Zhu L, Zhao XL, Chen H, Kang HX, Zhao JL, Wan MH, Li J, Zhu L, Tang WF*.Optimal timing for the oral administration of Da-Cheng-Qi decoction based on the pharmacokinetic and pharmacodynamic targeting of the pancreas in rats with acute pancreatitis.World J Gastroenterol. 2017 Oct 21;23(39):7098-7109.
18) Zhu L, Li JY, Zhang YM, Kang HX, Chen H, Su H, Li J, Tang WF*.Pharmacokinetics and pharmacodynamics of Shengjiang decoction in rats with acute pancreatitis for protecting against multiple organ injury.World J Gastroenterol. 2017;23(46):8169-8181.
19) Zhang YM, Ren HY, Zhao XL, Li J, Li JY, Wu FS, Su H, Tang WF*.Pharmacokinetics and pharmacodynamics of Da-Cheng-Qi decoction in the liver of rats with severe acute pancreatitis.World J Gastroenterol. 2017 Feb 28;23(8):1367-1374.
20) Li J, Chen J, Wenfu Tang*. The consensus of integrative diagnosis and treatment of acute pancreatitis-2017. J Evid Based Med. 2019. 12(1): 76-88.
21) 代曉玉,吳秋葶,姚佳琦,李娟,萬美華,唐文富* . 升降散治療急性胰腺炎並發多器官功能障礙機制研究[J].陝西中醫,2022,43(05):550-554.
22) 康鴻鑫, 唐文富*. 急性胰腺炎傷寒六經平脈辨證體系探索[J]. 中國中醫急症, 2020,29(1):100-104,108.
23) 趙先林,朱世峰,康鴻鑫,李娟,唐文富,萬美華.急性胰腺炎與表觀遺傳調控機制[J].臨床肝膽病雜誌,2020,36(01):227-230.
24) 趙先林, 吳秋葶, 易小琳, 萬美華, 唐文富*. 《傷寒雜病論》龍牡劑證治初探[J]. 四川中醫,2020, 38(6):44-47.
25) 康鴻鑫, 唐文富*. 唐文富教授從厥陰病論治重症急性胰腺炎恢復期臨證經驗[J]. 四川中醫, 2020, 38(7):22-24.
26) 唐春梅,唐文富*. 當歸芍藥散方論及其在急性胰腺炎中的臨床運用[J]. 光明中醫, 2020,35(23):3796-3798.
27) 唐文富*. 慢性胰腺炎中西醫結合診療共識意見(2020)[J]. 中國中西醫結合消化雜誌, 2020,28(10):731-739.
28) 陳歡, 蘇杭, 袁玲,苗藝凡,張玉梅,李娟,唐文富*. 電針配合大承氣湯協同調控急性胰腺炎大鼠肺腸損傷的機制研究[J]. 針刺研究, 2018, 43(6):7.
29) 李軍祥, 陳誩, 唐文富*. 急性胰腺炎中西醫結合診療共識意見(2017 年)[J]. 中國中西醫結合消化雜誌, 2017.
30) 康鴻鑫, 張玉梅, 任泓宇,唐文富.* 開鬼門防治重症急性胰腺炎並發急性肺損傷的機理探討[J]. 四川中醫, 2017, 35(10):4.
31) 蘇杭, 吳俊, 唐文富*. 電針調控促炎-抗炎反應減輕急性胰腺炎大鼠肺損傷的俞募配穴機理[J]. 亞太傳統醫藥, 2017, 13(008):16-18.
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