2007年 第一作者論文“A five-year follow up study on the pathological changes of gastric mucosa after H.pylori eradication,”被評為第四屆中國科協期刊優秀學術論文。 （中國科學技術協會）
2005年，研究“The Diagnosis of Nonerosive Reflux Disease Using High-resolution Endoscopy”獲得“Asian Pacific Digestive Week Distinguished Poster Award.”
2005年“Eight-year Follow-up Study ON The Morbidity of Gastric Cancer And The Pathological Changes Of Gastric Mucosa After H.pylori Eradication”研究，被The American Gastroenterological Association 評為當年全球40個重要研究之一 –TOP 40
從事消化內科的臨床、教學、科研工作30餘年，臨床經驗豐富。對幽門螺桿菌、胃食管反流病及早期胃癌有系列、深入的研究。連續十年承擔國家十一五、十二五科技支撐計畫，主持國家自然科學基金、衛生部、教育部等研究項目多項，發表研究文章100餘篇，在幽門螺桿菌的研究已列入世界先進行列。幽門螺桿菌作為人類最廣泛的感染源，與多種疾病發生有關。近二十年來，在幽門螺桿菌與胃癌關係的研究上，被世界幽門螺桿菌共識MasstrictIII，Masstrict IV和MasstrictV作為Ia級證據所引用。研究成果在2005年美國消化疾病周（消化領域世界頂級學術會議，2萬人參會）進行大會發言，並被選為當年的40篇優秀論文之一（Top40）。進行了2000多例中國兒童幽門螺桿菌感染情況的研究，為世界首創。研究成果被《Aliment Pharmacol Ther》和《Helicobacter》雜誌分別收錄。對幽門螺桿菌耐藥的研究也已取得了突破性進展，研究成果發表在國際消化病權威雜誌《American journal of gastroenterology》，影響因子10.755，多次在國際頂級消化病學術會議美國胃腸疾病周(DDW)，歐洲幽門螺桿菌會議，歐洲胃腸疾病周上做大會發言。代表性論文“A five-year follow-up study on the pathological changes of gastric mucosa afterH. pylori eradication ”獲第四屆中國科協期刊優秀學術論文，SCI他引次數達75次。
1.Jiang, WJ, Zhou, LY *, Lin, SR, et al. Metabolic profiles of gastric cancer cell lines with different degrees of differentiation. International Journal Of Clinical And Experimental Pathology. 2018;11(2): 869-875
2.Li Ya ZHOU*, Zhi Qiang SONG, Yan XUE, et al. Recurrence of Helicobacter pylori infection and the affecting factors: A follow-up study. Journal of Digestive Diseases 2017; 18; 47–55
3.Peng X, Zhou L*, Gong Y, et al. Non-pylori Helicobacters (NHPHs) Induce Shifts in Gastric Microbiota in Helicobacter pylori-Infected Patients. Front. Microbiol.2017;8:1038.
4.Song Z, Suo B, Zhang L, Zhou L*. Rabeprazole, Minocycline, Amoxicillin, and Bismuth as First-Line and Second-Line Regimens for Helicobacter pylori Eradication. Helicobacter. 2016 Dec;21(6):462-470.
5.Song ZQ, Zhou LY*. Esomeprazole, minocycline, metronidazole and bismuth as first-line and second-line regimens for Helicobacter pylori eradication. J Dig Dis. 2016;17:260-7.
6.Song Z, Zhou L*, Zhang J, He L, Bai P, Xue Y. Levofloxacin, bismuth, amoxicillin and esomeprazole as second-line Helicobacter pylori therapy after failure of non-bismuth quadruple therapy. Dig Liver Dis. 2016 May;48(5):506-11.
7.Zhou L*, Zhang J, Song Z, He L, Li Y, Qian J, Bai P, Xue Y, Wang Y, Lin S. Tailored versus Triple plus Bismuth or Concomitant Therapy as Initial Helicobacter pylori Treatment: A Randomized Trial. Helicobacter. 2016 ;21(2):91-9.
8.Z. Ding, S. Zhao, S. Gong, Z. Li, M. Mao, X. Xu, L. Zhou*. Prevalence and risk factors of Helicobacter pylori infection in asymptomatic Chinese children: a prospective, cross-sectional,population-based study. Aliment Pharmacol Ther 2015; 42: 1019–1026.
9.Yan XE, Zhou LY*, Lin SR, Wang Y, Wang YC. Therapeutic effect of esophageal foreign body extraction management: flexible versus rigid endoscopy in 216 adults of Beijing. Med Sci Monit. 2014 Oct 27;20:2054-60.
10.Song Z, Zhang J, He L, Chen M, Hou X, Li Z, Zhou L*. Prospective multi-region study on primary antibiotic resistance of Helicobacter pylori strains isolated from Chinese patients. Dig Liver Dis. 2014;46(12):1077-81.
11.Zhou L*, Lin S, Ding S, Huang X, Jin Z, Cui R, Meng L, Li Y, Zhang L, Guo C, Xue Y, Yan X, Zhang J. Relationship of Helicobacter pylori eradication with gastric cancer and gastric mucosal histological changes: a 10-year follow-up study. Chin Med J (Engl). 2014;127(8):1454-8.
12.Zhou L*, Zhang J, Chen M, Hou X, Li Z, Song Z, He L, Lin S. A comparative study of sequential therapy and standard triple therapy for Helicobacter pylori infection: a randomized multicenter trial. Am J Gastroenterol. 2014;109(4):535-41.
13.Zhou LY*, Wang Y, Lu JJ, Lin L, Cui RL, Zhang HJ, Xue Y, Ding SG, Lin SR. Accuracy of diagnosing gastroesophageal reflux disease by GerdQ, esophageal impedance monitoring and histology. J Dig Dis. 2014;15(5):230-8.
14.J. Huang, L. Zhou, L. Geng, M. Yang, X.-W. Xu, Z.-L. Ding, M. Mao, Z.-L. Wang, Z.-L. Li, D.-Y. Li, S.-T. Gong. Randomised controlled trial: sequential vs. standard triple therapy for Helicobacter pylori infection in Chinese children–a multicentre, open-labelled study. Aliment Pharmacol Ther 2013; 38: 1230–1235.
15.Deng K, Zhou LY*, Lin SR, Li Y, Chen M, Geng QM, Li YW. A novel approach for detection of early gastric cancer. J Dig Dis, 2013;14(6): 299-304.
16.Deng K, Lin S, Zhou L*, Li Y, Chen M, Wang Y, Li Y. High levels of aromatic amino acids in gastric juice during the early stages of gastric cancer progression. PLoS One, 2012;7(11): e49434.
17.Deng K, Lin S, Zhou L*, Geng Q, Li Y, Xu M, Na R. Three aromatic amino acids in gastric juice as potential biomarkers for gastric malignancies. Anal Chim Acta, 694(1-2): 100-107, 2011.
18.Zhou LY*, Lin SR, Li Y, Geng QM, Ding SG, Meng LM, Sun XN, Wang JT, Xu ZJ, Guo HL, Li CG, Cui RL. The intrinsic fluorescence spectrum of dilute gastric juice as a novel diagnostic tool for gastric cancer. J Dig Dis, 2011;12(4): 279-285.
19.Cui R, Zhou L*, Lin S, Xue Y, Duan L, Xia Z, Jin Z, Zhang H, Zhang J, Song Z, Yan X. The feasibility of light microscopic measurements of intercellular spaces in squamous epithelium in the lower-esophagus of GERD patients. Dis Esophagus, 24: 1-5, 2011.
20.Wang L, Zhou L, Lin S, Hu H, Xia J*. A new PPI, ilaprazole compared with omeprazole in the treatment of duodenal ulcer: a randomized double-blind multicenter trial. J Clin Gastroenterol, 45(4): 322-329, 2010.
21.Zhang DH, Zhou LY*, Dong XY, Cui RL, Xue Y, Lin SR. Factors influencing intercellular spaces in the rat esophageal epithelium. World J Gastroenterol, 16(9): 1063-1069, 2010.
22.Zhang DH, Zhou LY*, Lin SR, Ding SG, Huang YH, Gu F, Zhang L, Li Y, Cui RL, Meng LM, Yan XE, Zhang J. Recent changes in the prevalence of Helicobacter pylori infection among children and adults in high- or low-incidence regions of gastric cancer in China. Chin Med J (Engl). 2009;122(15):1759-63.
23.Xue Y, Zhou LY*, Lin SR. Dilated intercellular spaces in gastroesophageal reflux disease patients and the changes of intercellular spaces after omeprazole treatment. Chin Med J (Engl). 2008 Jul 20;121(14):1297-301.
24.Zhang L, Zhou LY*, Lin SR, Ding SG, Huang YH, Gu F, Li Y, Zhang J, Yan XE, Meng LM, Zhang DH, Huang SM, Qu XF. Reflux symptom questionnaire in the diagnosis of reflux oesophagitis. Chin Med J (Engl). 2007;120(23):2146-8.
25.Zhou L*, Sung JJ, Lin S, Jin Z, Ding S, Huang X, Xia Z, Guo H, Liu J, Chao W. A five-year follow-up study on the pathological changes of gastric mucosa after H. pylori eradication. Chin Med J (Engl). 2003;116(1):11-4.
