呂志強，男，博士，西北農林科技大學植物保護學院昆蟲學系教授，博士生導師。兼任中國昆蟲學會生理生化專業委員會、昆蟲發育與遺傳專業委員會、國際交流與工作委員會及中國植保學會生物安全委員會委員，陝西省昆蟲學會理事。
基本介紹
- 中文名：呂志強
- 職業：教師
- 畢業院校：美國俄克拉荷馬州立大學
- 學位/學歷：博士
- 專業方向：昆蟲學
- 任職院校：西北農林科技大學
人物經歷,研究方向,代表論文,
人物經歷
1990.9-1994.7 西北農林科技大學農學系本科生
1994.9-1997.7 西北農林科技大學生物化學專業碩士研究生
2002.8-2007.5 美國俄克拉荷馬州立大學昆蟲學博士研究生
1997.7-1998.7 華中農業大學 助教
1998.7-2000.10 重慶雨水集團生物醫藥研究所
2000.10-2002.8 國家生化工程中心（深圳） 工程師
2007.7-2009.7 美國喬治亞大學 博士後
2009.8- 西北農林科技大學植保學院 教授
研究方向
1. 豌豆蚜免疫系統研究；
2. 寄生蜂-寄主昆蟲免疫互作研究；
3.昆蟲免疫與發育調控。
代表論文
Xu L, Ma L, Wang W, Li L, Lu Z. Phenoloxidases Are Required for the Pea Aphid Defense against Bacterial and Fungal Infection. Insect Molecular Biology. doi.org/10.1111/imb.12536 (in press)
Ma L, Zhou L, Lin J, Ji J, Wang Y, Jiang H, Shen X, Lu Z (2019) Manipulation of the silkworm immune system by a metalloprotease from the pathogenic bacterium Pseudomonas aeruginosa. Developmental & Comparative Immunology. 90:176-185.
Lin Z, Cheng Y, Wang R-J, Du J, Volovych O, Li J-C, Hu Y, Lu Z-Y, Lu Z, Zou Z (2019) A Metalloprotease Homolog Venom Protein From a Parasitoid Wasp Suppresses the Toll Pathway in Host Hemocytes. Frontiers in Immunology. 9:2301.
Chen K, Lu Z (2018) Immune responses to bacterial and fungal infections in the silkworm, Bombyx mori. Developmental & Comparative Immunology. 83:3-11.
Si M, Wang T, Pan J, Lin J, Chen C, Wei Y, Lu Z, Wei G, Shen X. (2017) Graded Response of the Multifunctional 2-Cysteine Peroxiredoxin, CgPrx, to Increasing Levels of Hydrogen Peroxide in Corynebacterium glutamicum. Antioxidants & Redox Signaling. 26, 1–14.
Wang R-J, Lin Z, Jiang H, Li J, Saha TT, Lu Z, Lu Z, Zou Z (2017) Comparative analysis of peptidoglycan recognition proteins in endoparasitoid wasp Microplitis mediator. Insect Science. 24:2–16.
Su L-D, Zhang Q-L, Lu Z (2017) Oxidation resistance 1 (OXR1) participates in silkworm defense against bacterial infection through the JNK pathway. Insect Science. 24:17–26.
Li J, Ma L, Lin Z, Zou Z, Lu Z (2016) Serpin-5 regulates prophenoloxidase activation and antimicrobial peptide pathways in the silkworm, Bombyx mori. Insect Biochemistry and Molecular Biology. 73: 27-37
Chen K, Zhou L, Chen F, Peng Y, Lu Z (2016) Peptidoglycan recognition protein-S5 functions as a negative regulator of the antimicrobial peptide pathway in the silkworm, Bombyx mori. Developmental & Comparative Immunology. 61:126-135.
Otho SA, Chen K, Zhang Y, Wang P, Lu Z (2016) Silkworm ferritin 1 heavy chain homolog is involved in defense against bacterial infection through regulation of haemolymph iron homeostasis. Developmental & Comparative Immunology. 55:152-158.
Zhang Y, Lu Z (2015) Peroxiredoxin 1 protects the pea aphid Acyrthosiphon pisum from oxidative stress induced by Micrococcus luteus infection. Journal of Invertebrate Pathology. 127: 115–121.
Zhang L, Wang Y-W, Lu Z (2015) Midgut immune responses induced by bacterial infection in the silkworm, Bombyx mori. Journal of Zhejiang University Science B. 16: 875-882.
Ding W, Si M, Zhang W, Zhang Y, Chen C, Zhang L, Lu Z, Chen S, Shen X (2015) Functional characterization of a vanillin dehydrogenase in Corynebacterium glutamicum. Scientific Reports. 5: 8044.
Zhang L, Lu Z (2015) Expression, purification, and characterization of an atypical 2-Cys peroxiredoxin from the silkworm, Bombyx mori. Insect Molecular Biology. 24(2): 203–212
Chen K, Liu C, He Y, Jiang H, Lu Z (2014) A short-type peptidoglycan recognition protein from the silkworm: Expression, characterization and involvement in the prophenoloxidase activation pathway. Developmental & Comparative Immunology 45: 1-9.
Wang Y, Lu Z, Jiang H (2014) Manduca sexta proprophenoloxidase activating proteinase-3 (PAP3) stimulates melanization by activating proPAP3, proSPHs, and proPOs. Insect Biochemistry and Molecular Biology 50: 82-91.
Liu YB, Long MX, Yin YJ, Si MR, Zhang L, Lu ZQ, Wang Y, Shen XH (2013) Physiological roles of mycothiol in detoxification and tolerance to multiple poisonous chemicals in Corynebacterium glutamicum. Archives of Microbiology. Archives of Microbiology 195:419-429.
Shao Q, Yang B, Xu Q, Li X, Lu Z, et al. (2012) Hindgut Innate Immunity and Regulation of Fecal Microbiota through Melanization in Insects. Journal of Biological Chemistry 287: 14270-14279.
Zhao P, Lu Z, Strand MR, Jiang H (2011) Antiviral, anti-parasitic, and cytotoxic effects of 5,6-dihydroxyindole (DHI), a reactive compound generated by phenoloxidase during insect immune response. Insect Biochemistry and Molecular Biology 41: 645-652.
Lu Z, Beck MH, Strand MR (2010) Egf1.5 is a second phenoloxidase cascade inhibitor encoded by Microplitis demolitor bracovirus. Insect Biochemistry and Molecular Biology 40: 497-505.
Clark KD, Lu Z, Strand MR (2010) Regulation of melanization by glutathione in the moth Pseudoplusia includens. Insect Biochemistry and Molecular Biology 40: 460-467.
Lu Z, Beck MH, Wang Y, Jiang H, Strand MR (2008) The Viral Protein Egf1.0 Is a Dual Activity Inhibitor of Prophenoloxidase-activating Proteinases 1 and 3 from Manduca sexta. Journal of Biological Chemistry 283: 21325-21333.
Tribolium Genome Sequencing Consortium: Immunity: Zhen Zou, Jay Evans, Zhiqiang Lu, Picheng Zhao, Niranji Sumathipala, Boran Altincicek, Andreas Vilcinskas, Michael Williams, Dan Hultmark, Charles Hetru, Haobo Jiang (2008) The genome of the model beetle and pest Tribolium castaneum. Nature, 452(7190): 949-955.
Lu Z, Jiang H (2008) Expression of Manduca sexta serine proteinase homolog precursors in insect cells and their proteolytic activation. Insect Biochemistry and Molecular Biology 38: 89-98.
Huang R, Lu Z, Dai H, Vander Velde D, Prakash O, Jiang H (2007) The Solution Structure of Clip Domains from Manduca sexta Prophenoloxidase Activating Proteinase-2. Biochemistry 46: 11431-11439.
Zou Z, Evans J, Lu Z, Zhao P, Williams M, Sumathipala N, Hetru C, Hultmark D, Jiang H (2007) Comparative genomic analysis of the Tribolium immune system. Genome Biology 8: R177.
Lu Z, Jiang H (2007) Regulation of phenoloxidase activity by high- and low-molecular-weight inhibitors from the larval hemolymph of Manduca sexta. Insect Biochemistry and Molecular Biology 37: 478-485.
Zhang G, Lu Z-Q, Jiang H, Asgari S (2004) Negative regulation of prophenoloxidase (proPO) activation by a clip-domain serine proteinase homolog (SPH) from endoparasitoid venom. Insect Biochemistry and Molecular Biology 34: 477-483.
Jiang H, Ma C, Lu Z, Kanost MR. (2004) β-1,3-Glucan recognition protein-2 (βGRP-2) from Manduca sexta: an acute-phase protein that binds β-1,3-glucan and lipoteichoic acid to aggregate fungi and bacteria and stimulate prophenoloxidase activation. Insect Biochemistry and Molecular Biology 34: 89-100.
張永棟, 李君蘭, 陳金紅, 馬力, 陳康康, 呂志強 (2017) Identification and characterization of peroxiredoxin 2 involved in the antioxidative response induced by bacterial infection in the pea aphid， Acyrthosiphon pisum (Hemiptera： Aphididae). 昆蟲學報. 60(3)：254-263
陳金紅, 徐露, 馬力, 呂志強 (2017) 過氧化氫酶在豌豆蚜抵禦藤黃微球菌和大腸桿菌感染引起的氧化脅迫中的作用. 昆蟲學報.60(10)：1178-1186
張巧伶, 蘇立德, 呂志強 (2015) 細菌感染對家蠶DNA甲基化與組蛋白乙醯化相關基因表達的影響. 昆蟲學報. 58 (9): 941-949
陳康康，呂志強 (2014) 昆蟲肽聚糖識別蛋白研究進展. 昆蟲學報. 57(8)：969-978.
王鵬，王維，呂志強 (2014) 家蠶半乳糖凝集素BmGalectin-4的表達、純化及性質分析. 昆蟲學報. 57(7): 806-814.
朱艷菊，呂志強 (2013) Identification of differentially expressed genes in the larval midgut of the silkworm (Bombyx mori) after bacterial infection. 昆蟲學報. 56(5): 505-511.
