個人簡歷
2004年11月至今任上海交通大學生命科學技術學院教授、博士生導師。曾主持上海市浦江人才計畫基金、教育部高等學校博士點基金和教育部留學回國人員基金。現主持國家自然科學基金重點項目, 國家自然科學基金重大研究計畫培育項目, 農業部重大項目子課題和科技部重大研究計畫子課題。已在Nature Cell Biology, Molecular Biology of the Cell, Developmental Biology, Cellular Signalling, Journal of Cellular Physiology, Biology of Reproduction, Cell Proliferation, Fertility and Sterility, Human Reprodution, Journal of Endocrinology等重要學術刊物上發表論文近50篇。受邀為FEBS J, Reproductive Biology and Endocrinology, DNA and Cell Biology 等雜誌撰寫綜述。最新研究成果—發現成年哺乳動物卵巢內具有自我更新和分化潛能的生殖幹細胞,開闢了一個嶄新研究領域。Science,Nature, Nature Medicine和眾多家雜誌刊發評論文章,Nature China將這一成果列入最新研究亮點。為國際Faculty of 1000 Biology推薦論文,世界各大媒體(包括《
紐約時報》、《
華盛頓郵報》、《
路透社》、《美國廣播公司新聞》(ABC News)、《
泰晤士報》(The Times)等)紛紛報導。現為美國Reproductive Biology and Endocrinology 雜誌Adviser,美國American Journal of Biochemistry and Biotechnology 雜誌客座編輯,香港研究資助局大學教育資助委員會國際評審, 中國組織工程研究與臨床康複雜志編委,Stem Cell Reviews and Reports, Cell Proliferation, Developmental Dynamics, Cloning and Stem Cells, DNA and Cell Biology 等十餘家雜誌特邀審稿人。
研究方向
1. 幹細胞生物學。
2. 分子生殖生物學。
發表論文
(回國後以上海交大為第一單位發表的SCI論文)
1. Zou K, Yuan Z, Yang Z, Luo H, Sun K, Zhou L, Xiang J, Shi L, Yu Q, Zhang Y, Hou R, Wu J. Production of offspring from a germline stem cell line derived from ovaries. Nature Cell Biology 2009; 11: 631-636 (通訊作者, Table of Contents Cover Story).
2. Yuan Z., Hou R., Wu J. Generation of mice by transplantation of an adult spermatogonial cell line after cryopreservation. Cell proliferation 2009; 42: 123-131 (通訊作者)
3.Zhang Y., Wu J. Molecular cloning and characterization of a new gene, Oocyte-G1. J cell Physiol 2009; 218: 75-83 (通訊作者) (Cover Story)
4. Shi L, Wu J. Epigenetic regulation in mammalian preimplantation embryo development. Reproductive Biology and Endocrinology 2009; 7:59 (通訊作者)
5. Yu Q., Wu J. Involvement of cyclins in mammalian spermatogenesis. Mol Cell Biochem. 2008; 315(1-2): 17-24 (通訊作者).
6. Yang Z., Wu J. Mouse Dynein Axonemal Intermediate Chain 2: Cloning and Expression. DNA and Cell Biology 2008; 27: 479-488 (通訊作者) (Cover Story)
7. Wu J., Zhang Y., Tian G.G., Zou K., Lee C.M., Yu Q., Yuan Z. Short-type PB-cadherin promotes self-renewal of spermatogonial stem cells via multiple signaling pathways. Cell Signal. 2008; 20: 1052-1060 (通訊作者)
8. Zhang Y., Yang Z., Wu J. Signaling pathways and preimplantation development of mammalian embryos. FEBS J 2007; 274: 4349-4359 (通訊作者)
9. Yang Z., Wu J. MicroRNAs and Regenerative Medicine. DNA and Cell Biology 2007; 26: 257-246 (通訊作者)
10. Wu J., Tian Q. Role of follicle stimulating hormone and epidermal growth factor in the development of porcine preantral follicle in vitro. Zygote 2007; 15: 233-240 (通訊作者)
11. Wu J., Xu B., Wang W. Effects of luteinizing hormone and follicle stimulating hormone on the developmental competence of porcine preantral follicle oocytes grown in vitro. J Assist Reprod Genet 2007; 24: 419-424 (通訊作者)
12. Yang, Z., Wu, J. Small RNAs and development. Med Sci Monit 2006; 12: RA125-129 (通訊作者)
學術著書 (英文)
1. Wu, J., Yang Z. MicroRNAs and Regenerative Medicine, in:Current Perspective in microRNAs., Springer 10(2008)ISBN-13: (參編)
2. Wu, J. Small RNAs and signaling pathways in development, in: Recent Res. Devel. Mol. Cell. Biol., Research Signpost, Inc., Kerala, India, 6 (2006) ISBN: 81-308-01310(合著)
學術譯著
幹細胞移植-機理和臨床. 主譯: 吳際. 科學出版社. 2008年6月 第一版