吳衛輝,男,博士,南開大學生命科學學院微生物學系教授。1998年和2001年分別獲得南開大學學士和碩士學位,然後赴美國留學。2006年獲得美國佛羅里達大學博士學位。
基本介紹
- 中文名:吳衛輝
- 國籍:中國
- 職稱:教授
- 性別:男
簡介,工作經歷,研究方向,主要著作,
簡介
工作經歷
2006--2009 美國德克薩斯大學M.D.安德森癌症研究中心 博士後
2009--2011 美國哈佛大學醫學院布雷根及婦女醫院 博士後
2011--至今 南開大學生命科學學院 教授
研究方向
致病菌毒性基因的表達調控及作用機制;
致病菌耐藥機理研究;
宿主在感染過程中的免疫反應。
主要著作
1. Wu W, Huang J, Duan B, Traficante DC, Hong H, Risech M, Lory S, Priebe GP. Th17-stimulating protein vaccines confer protection against Pseudomonas aeruginosa pneumonia. Am. J. Respir. Crit. Care Med. 2012, in press. (IF=10)
2. Bi L, Gojestani S, Wu W, Hsu YM, Zhu J, Ariizumi K, Lin X. (2010) CARD9 mediates dectin-2-induced IkappaBalpha kinase ubiquitination leading to activation of NF-kappaB in response to stimulation by the hyphal form of Candida albicans. J Biol Chem. 285(34):25969-77.
3. Wu, W., YM. Hsu, L. Bi, Z. Songyang, X. Lin. (2009) CARD9 facilitates microbe-elicited production of reactive oxygen species by regulating the LyGDI-Rac1 complex. Nat Immunol. 10(11):1208-14. (IF=25)
4. Ha, U., J-H. Lim, W. Wu, S. Jin and J-D. Li. (2008) MKP1 regulates the induction of MUC5AC Mucin by S. pneumoniae Pneumolysin by inhibiting the PAK4-JNK signaling pathway. J Biol Chem. 283(45):30624-31..
5. Yang, H., Z. Shan, J. Kim, W. Wu, W. Lian, L. Zeng, L. Xing and S. Jin. (2007) Regulatory role of PopN and its interacting partners in type III secretion of Pseudomonas aeruginosa. J Bacteriol. 189(7):2599-609
6. Wu, W., Y. Song, S. Jin and S. Chen. (2006) An Interactive Map of Regulatory Networks of Pseudomonas aeruginosa Genome. Systems Biology and Regulatory Genomics of Lecture Notes in Computer Science. 4023: 1-10.
7. Jyot, J., A. Sonawane, W. Wu and R. Ramphal. (2007) Genetic mechanisms involved in the repression of flagellar assembly by Pseudomonas aeruginosa in human mucus. Mol Microbiol. 63(4):1026-38.
8. Wu, W. and S. Jin. (2005) PtrB of Pseudomonas aeruginosa Suppresses Type III Secretion System Under the Stress of DNA Damage. J Bacteriol. 187(17):6058-68.(IF=4)
9. Wu, W., H. Badrane, S. Arora, H. Baker and S. Jin. (2004) MucA-mediated coordination of type III secretion and alginate synthesis in Pseudomonas aeruginosa. J Bacteriol. 186(22):7575-85.(IF=4)
(注: 上述括符中的IF為該學術期刊的影響因子Impact Factor)