吳義麗

吳義麗,女,博士,1979年10月生,青島大學公共衛生學院教授。

基本介紹

  • 中文名:吳義麗
  • 學位/學歷:博士
  • 職業:教師
  • 任職院校:青島大學公共衛生學院
  • 職稱:教授
個人經歷,研究方向,開授課程,科研項目,學術成果,

個人經歷

安徽馬鞍山人。醫學博士,教授,碩士生導師。
山東預防醫學會流行病學分會委員。

研究方向

1. 肥胖的遺傳病因學機制。基於青島市雙生子募集登記系統,將分子生物學技術和傳統流行病學方法相結合,開展成人肥胖的遺傳病因學研究,從基因序列變異和表觀遺傳修飾效應兩個角度,全面探索肥胖的致病機制和疾病生物學通路。
2. 環境因素對慢性非傳染病的影響。利用《青島市糖尿病佇列》、國內外公共資料庫、以及Meta分析的方法,探索睡眠、體力活動、水果蔬菜攝入、微量元素攝入、鎘暴露、高尿酸對肥胖、2型糖尿病、高血壓、乳腺癌、軀體功能、認知功能、抑鬱等疾病/表型的影響,為社區慢性病的防治工作及健康老齡化工作提供理論依據。

開授課程

主要從事慢性非傳染病流行病學分子流行病學研究工作和衛生統計學教學工作。

科研項目

作為負責人主持國家級課題2項,省部級課題2項,市廳級課題2項
1.基於表型不一致成年同卵雙生子的肥胖全基因組甲基化譜和表達譜分析,國家自然科學基金面上項
目,50萬元,2018-2021,主持。
2.基於目標序列捕獲測序技術的成人肥胖易感基因研究,中國博士後科學基金會,5萬元,2016-2018,
主持。
3.基於染色體7q36.3區域捕獲測序的肥胖易感基因研究,青島市博士後人員套用研究項目,5萬元,
2016-2018,主持。
4.染色體7q36.3區域遺傳變異與成人肥胖表型的關聯研究,國家自然科學基金青年基金,23萬元,2014-
2016,主持。
5.染色體7q36.3區域遺傳變異與2型糖尿病的關聯研究,山東省博士基金,5萬元,2014-2016,主持。

學術成果

以第一作者或通訊作者身份,發表SCI收錄論文18篇,其中ESI 高被引論文1篇,中科院JCR一區論文1篇,二區論文8篇。Web of science總計他引200餘次。
(1)學術論文
第一作者
1.Wu Y#, Duan H, Tian X, Xu C, Wang W, Jiang W, Pang Z, Zhang D, Tan Q. Genetics of Obesity Traits: A Bivariate Genome-Wide Association Analysis. Front Genet. 2018.
2.Wu Y, Wang W, Liu T, Zhang D#. Association of Grip Strength With Risk of All-Cause Mortality, Cardiovascular Disease, and Cancer in Community-Dwelling Populations: A Meta-analysis of Prospective Cohort Studies. J Am Med Dir Assoc. 2017.
3.Wu Y#, Wang W, Jiang W, Yao J, Zhang D. An investigation of obesity susceptibility genes in Northern Han Chinese by targeted resequencing. Medicine(Baltimore). 2017 Feb.
4.Wu Y, Zhang D#. Meta-analyses of etiologic studies should account for the underlying biologic mechanisms. Breast Cancer Res Treat. 2015 Feb.
5.Wu Y, Zhang D#, Pang Z, Jiang W, Wang S, Li S, von Bornemann Hjelmborg J, Tan Q. Multivariate modeling of body mass index, pulse pressure, systolic and diastolic blood pressure in Chinese twins. Twin Res Hum Genet. 2015 Feb.
6.Wu Y, Zhang D#, Jiang X, Jiang W. Fruit and vegetable consumption and risk of type 2 diabetes mellitus: a dose-response meta-analysis of prospective cohort studies. Nutr Metab Cardiovasc Dis. 2015 .
7.Wu Y#, Zhai L, Zhang D. Sleep duration and obesity among adults: a meta-analysis of prospective studies. Sleep Med. 2014 Dec.
8.Wu Y, Li S, Zhang D#. Circulating 25-hydroxyvitamin D levels and hypertension risk. Eur J Epidemiol. 2013 Jul.
9.Wu Y, Zhang D#, Kang S. Black tea, green tea and risk of breast cancer: an update. Springerplus. 2013 May 24.
10.Wu Y, Zhang D#, Kang S. Physical activity and risk of breast cancer: a meta-analysis of prospective studies. Breast Cancer Res Treat. 2013 Feb.
11.Wu Y, Zhang D#, Pang Z, Jiang W, Wang S, Tan Q. Association of serum uric acid level with muscle strength and cognitive function among Chinese aged 50-74 years. Geriatr Gerontol Int. 2013 Jul.
12.Wu Y, Zhang D#, Pang Z, Oksuzyan A, Jiang W, Wang S, Li S, Kruse T, Christensen K, Tan Q. Gender-specific patterns in age-related decline in general health among Danish and Chinese: a cross-national comparative study. Geriatr Gerontol Int. 2012 Jul.
13.Wu Y, Pang Z#, Zhang D#, Jiang W, Wang S, Li S, Kruse TA, Christensen K, Tan Q.A cross-sectional analysis of age and sex patterns in grip strength, tooth loss, near vision and hearing levels in Chinese aged 50-74 years. Arch Gerontol Geriatr. 2012 Mar-Apr.
通訊作者
1.Wang T, Wu Y#, Li W, Li S, Sun Y, Li S, Zhang D, Tan Q. Weak Grip Strength and Cognition Predict Functional Limitation in Older Europeans. J Am Geriatr Soc. 2018 . [Epub ahead of print]
2.Wang TY, Wu Y#, Wang T, Li Y, Zhang D. A prospective study on the association of sleep duration with grip strength among middle-aged and older Chinese. Exp Gerontol. 2018.
3.Li Y, Wu Y#, Zhai L, Wang T, Sun Y, Zhang D, Longitudinal Association of Sleep Duration with Depressive Symptoms among Middle-aged and Older Chinse. Sci Rep. 2017.
4.Wang T, Wu Y#, Sun Y, Zhai L, Zhang D. A Prospective Study on the Association between Uric Acid and Cognitive Function among Middle-Aged and Older Chinese. J Alzheimers Dis. 2017.
5.Li Y, Zhang Y, Wang W, Wu Y#. Association of urinary cadmium with risk of diabetes: a meta-analysis. Environ Sci Pollut Res Int. 2017 Ap.

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