吳彩勝，男，博士，廈門大學藥學院教授。
基本介紹
- 中文名：吳彩勝
- 學位/學歷：博士
- 職業：教師
- 專業方向：常用中草藥及其複方代謝研究、新藥質量控制和藥代研究
- 任職院校：廈門大學藥學院
個人經歷,研究方向,學習成果,
個人經歷
2006年取得中國藥科大學中藥學理學學士學位，2011年獲北京協和醫學院藥物分析博士學位。2011年-2015年在中國醫學科學院藥物研究所國家藥物及代謝產物分析研究中心工作。2015年10月調動到廈門大學藥學院從事藥物分析和藥物代謝相關專業研究。
教育經歷:
2002年-2006年 中國藥科大學中藥學院
2006年-2011年 中國醫學科學院藥物研究所
研究方向
常用中草藥及其複方代謝研究、新藥質量控制和藥代研究等
學習成果
主持國家自然科學基金面上項目、青年基金，福建省自然科學基金面上項目、北京市自然科學基金預探索項目等多項基金。在AnalyticalChemistry,DrugMetabolismandDispostion等藥物分析和藥物代謝前沿雜誌上發表研究論文30餘篇。
主持研究項目
- 國家自然科學基金面上項目：基於HRMS/MS數據集挖掘技術的斑馬魚體內ADME分析策略的建立及其在中藥降糖藥效物質群快速篩選中的套用
- 國家自然科學基金新疆聯合基金培育項目：基於“AcquireX 智慧型數據採集”等非靶向質譜分析技術策略探究天山雪蓮的體內藥效物質基礎
- 國家自然科學基金青年基金：中藥名方二仙湯調節脂代謝紊亂的物質基礎及其作用通路研究
- 北京市自然科學基金：中藥名方小續命湯有效成分組在大鼠腦內代謝分布特點研究
- 福建省自然科學基金面上項目：基於“體內ADME過程-多元信息統計-計算機輔助找靶”技術策略探究大黃甘草湯的體內藥效物質基礎
- 國家科技平台聯合專題服務：面向脂質組學研究的脂質化合物專題資料庫
- 公益性事業單位基本科研業務費：基於脂質組學技術的金黃地鼠高脂血症藥效評價模型的建立
代表性成果
部分發表論文
Caisheng Wu, Haiying Zhang, Caihong Wang, et al. An integrated approach for studying exposure, metabolism, and disposition of multiple component herbal medicines using high-resolution mass spectrometry and multiple data processing tools. Drug Metabolism and Disposition
Caihong Wang, Caisheng Wu, Lin Zhang, et al. Ultraperformance liquid chromatography-tandem mass spectrometry method for profiling ketolic and phenolic sex steroids using an automated injection program combined with diverter valve switch and step analysis, Analytical Chemistry
Caihong Wang, Zhixin Jia, Zhe Wang, Ting Hu, Hailin Qin, Guanhua Du, Caisheng Wu*, Jinlan Zhang*. Pharmacokinetics of 21 active components in focal cerebral ischemic rats after oral administration of the active fraction of Xiao-Xu-Ming decoction. Journal of Pharmaceutical and Biomedical Analysis
Thibaud Thiollier, Caisheng Wu, Hugues Contamin, et al. Permeability of blood-brain barrier in macaque model of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced Parkinsondisease. Synapse
Caihong Wang, Caisheng Wu, Jinlan Zhang, et al. Systematic considerations for a multicomponent pharmacokinetic study of Epimedii wushanensis herba: From method establishment to pharmacokinetic marker selection. Phytomedicine
Zhe Wang, Caisheng Wu, Gang-Li Wang, et al. Novel strategy for the determination of illegal adulterants in health foods and herbal medicines using high-performance liquid chromatography with high-resolution mass spectrometry. Journal of Separation Science
Ying Jin, Caisheng Wu*, Jinlan Zhang*, et al., A new strategy for the discovery of epimedium metabolites using high-performance liquid chromatography with high resolution mass spectrometry, Analytica Chimica Acta
Caisheng Wu, Yuanfeng Tong, Pengyuan Wang, et al., Identification of impurities in methotrexate drug substances using high-performance liquid chromatography coupled with a photodiode array detector and Fourier transform ion cyclotron resonance mass spectrometry, Rapid Communications in Mass Spectrometry
Caisheng Wu, Jinlan Zhang*, Tonghui Zhou, et al., Simultaneous determination of seven flavonoids in dog plasma by ultra-performance liquid chromatography–tandem mass spectrometry and its application to a bioequivalence study of bioactive components in Herba Epimedii and Er-Xian Decoction, Journal of Pharmaceutical and Biomedical Analysis
Caisheng Wu, Yuxin Sheng, Yinghao Zhang, et al., Identification and characterization of active compounds and their metabolites by high-performance liquid chromatography/Fourier transform ion cyclotron resonance mass spectrometry after oral administration of a herbal extract of Epimedium koreanum Nakai to rats, Rapid Communications in Mass Spectrometry
Caisheng Wu, Ying Jin, Jinlan Zhang*, et al., Simultaneous determination of seven prohibited substances in cosmetic products by liquid chromatography–tandem mass spectrometry, Chinese Chemical Letters
Caisheng Wu, Jinlan Zhang, Yanling Qiao, et al., Simultaneous determination of 14 b-lactam antibiotics in cosmetic products by liquid chromatography tandem mass spectrometry method, Chinese Chemical Letters
Caisheng Wu, Caihong Wang, Jinlan Zhang*, et al., Separation, determination of six impurities in methotrexate drug substance using ultra-performance liquid chromatography, Chinese Chemical Letters
Caisheng Wu, Zhixin Jia, Baoming Ning*, et al., Separation and identification of moxifloxacin impurities in drug substance by high-performance liquid chromatography coupled with ultraviolet detection and Fourier transform ion cyclotron resonance mass spectrometry, Chinese Chemical Letters
Caisheng Wu, Baolin Guo, Yuxin Sheng, et al., Simultaneous determination of seven flavonoids in Epimedium by liquid chromatography–tandem mass spectrometry method, Chinese Chemical Letters
Caihong Wang, Caisheng Wu, Hailin Qin, et al., Rapid discovery and identification of 68 compounds in the active fraction from Xiao-Xu-Ming decoction (XXMD) by HPLC-HRMS and MTSF technique, Chinese Chemical Letters
吳彩勝, 王亦琳, 張金蘭*, 等. HPLC-MS/MS法測定銀杏7種有效成分在犬血漿中濃度以及銀杏葉酊劑的相對生物利用度, 中國新藥雜誌
金瀅, 張金蘭, 吳彩勝*, 等. 柱前衍生化HPLC法測定疏血通注射液及其原藥材中糖的含量, 中國新藥雜誌,
專著：
毒代動力學，電子科技大學出版社，2014年09月，編著
