劉美玲，女，湖南師範大學教授，博士生導師。2006年碩士畢業留校工作，2009-2012年在職攻讀博士學位。2017年6月-2018年6月在加州大學洛杉磯分校訪學。一直從事光、電分析化學與感測領域的研究工作，在功能化有機化合物的合成、表征和套用，紅外光譜、壓電光譜電化學、納米材料功能化與套用等領域完成了一些創新研究工作，曾獲湖南省優秀博士論文和湖南省優秀碩士論文獎，湖南省自然科學獎二等獎（排名第二）。在Adv. Mater., Anal.Chem., Chem. Commun.，ACS sensors, ACS Appl. Mater &Interfaces, Biosens. Bioelectron., J. Agri. Food Chem., Electrochim. Acta和《分析化學》等國內外刊物發表論文70多篇。主持和完成3項國家自然科學基金和多項湖南省科技廳和教育廳課題等項目。
基本介紹
- 中文名：劉美玲
- 國籍：中國
- 民族：漢
- 出生地：瀏陽
- 畢業院校：湖南師範大學
- 學位/學歷：博士
- 職業：教師
- 專業方向：化學
人物經歷,研究方向,主要成就,獲獎記錄,
人物經歷
1999-2003年，湖南文理學院攻讀化學本科；
2003-2006年，湖南師範大學攻讀分析化學碩士學位；
2009-2012年，湖南師範大學攻讀分析化學博士學位；
2017年6月-2018年6月，加州大學洛杉磯分校訪學。
研究方向
1、納米材料的表面調控及生物感測研究；2、高性能電催化劑製備與套用；3、MOF及其衍生物的製備與套用；4、電化學及新型電子化學材料研究。
主要成就
主持課題：
1. 多功能“智慧型納米卷”的製備及其在癌症診斷、監測與治療中的套用，2020.01~2023.12，國家自然科學基金。
2. 基於碳點和新型植物提取物製備的雙金屬納米材料及套用，2017.01~2017.12國家自然科學基金。
3. 基於新型二茂鐵衍生物/功能化石墨烯納米材料修飾電極的電化學感測研究，2013.01 ~2016.12，國家自然科學基金青年基金。
4. 二維多孔納米片/金屬納米簇多功能納米複合物的製備及其在生化分析與疾病診斷中的套用，2019.01~2021.12，湖南省教育廳優秀青年基金。
6. 新型二茂鐵衍生物功能化碳納米材料修飾電極的構建及感測研究，2014.01~2016.12，湖南大學化學生物感測與計量學國家重點實驗室開放課題。
7. 新型二茂鐵衍生物功能化碳納米的製備及套用，2014.01~2016.12，湖南省教育廳優秀青年基金。
主要發表的論文
2019年
1. Li, P.; Wang, J.; Chen, H.; Sun, X.; You, J.; Liu, S.; Zhang,Y.;Liu, M.; Niu, X.;Luo, Y. Synergisticelectrocatalytic N2 reduction using a PTCA nanorod-rGO hybrid.Journal of Materials Chemistry A 2019, 7 (20), 12446.
2. Li, P.; Liu, Z.; Wu, T.; Zhang, Y.; Wang, L.; Wang, L.; Ji, L.;Zhang, Y.; Luo, Y.; Wang, T.; Liu, S.; Wu, Y.;Liu, M.; Sun, X.;Ambient electrocatalytic N2 reduction to NH3 by metalfluorides, J. Mater. Chem. A,2019, 7, 17761.
3. Li, P.; Zhao, R.; Chen, H.; Wang, H.; Wei, P.; Huang, H.; Liu,Q.; Li, T.; Shi, X.; Zhang, Y.;Liu, M.;Sun, X. Recent advancesin the development of water oxidation electrocatalysts at mild pH. Small 2019,15 (13).
4. Liu, M. ; Zhao,Z.; Duan, X.*, Huang, Y.* Nanoscale structure design for high-performance Pt-based ORR catalysts.Advanced Materials 2019, 31 (6).
5. Ma, Z.; Wu, T.; Li, P.;Liu,M.Huang, S.; Li, H.; Zhang, Y.; Yao, S. A dual (colorimetricand fluorometric) detection scheme for glutathione and silver (I) based on theoxidase mimicking activity of MnO2 nanosheets. Microchimica Acta2019, 186 (8).
6. Mo, F.; Ma, Z.; Wu, T.;Liu,M.; Zhang, Y.; Li, H.; Yao, S. Holey reduced graphene oxideinducing sensitivity enhanced detection nanoplatform for cadmium ions based onglutathione-gold nanocluster. Sensors and Actuators B-Chemical 2019, 281, 486.
7. Mo, F.; Xie, J.; Wu, T.;Liu,M.; Zhang, Y.; Yao, S. A sensitive electrochemical sensor forbisphenol A on the basis of the AuPd incorporated carboxylic multi-walledcarbon nanotubes. Food Chemistry 2019, 292, 253.
8. Wu, T.; Hou, W.; Ma, Z.;Liu,M.; Liu, X.; Zhang, Y.; Yao, S. Colorimetric determination ofascorbic acid and the activity of alkaline phosphatase based on the inhibitionof the peroxidase-like activity of citric acid-capped Prussian Blue nanocubes.Microchimica Acta 2019, 186 (2).
9. Wu, T.; Li, P.; Wang, H.; Zhao, R.; Zhou, Q.; Kong, W.; Liu, M.; Zhang, Y.; Sun,X.; Gong, F. Biomass-derived oxygen-doped hollow carbon microtubes forelectrocatalytic N2-to-NH3 fixation under ambientconditions. Chemical Communications 2019, 55 (18), 2684.
10. Wu, T.; Ma, Z.; Li, P.; Liu,Liu, M.; X.; Li, H.; Zhang,Y.; Yao, S. Colorimetric detection of ascorbic acid and alkaline phosphataseactivity based on the novel oxidase mimetic of Fe-Co bimetallic alloyencapsulated porous carbon nanocages. Talanta 2019, 202, 354.
11. Wu, T.; Ma, Z.; Li, P.; Lu, Q.; Liu, M.; Li, H.; Zhang,Y.; Yao, S. Bifunctional colorimetric biosensors via regulation of the dualnanoenzyme activity of carbonized FeCo-ZIF. Sensors and Actuators B-Chemical2019, 290, 357.
12. Yao, J.; Wu, T.; Sun, Y.; Ma, Z.;Liu, M.; Zhang, Y.; Yao, S.A novel biomimetic nanoenzyme based on ferrocene derivative polymer NPs coatedwith polydopamine. Talanta 2019, 195, 265.
2018年
1. Zhang, Q.; Wang, F.; Zhang, H.; Zhang, Y.;Liu, M.*; Liu, Y.* Universal Ti3C2MXenes Based Self-Standard Ratiometric Fluorescence Resonance Energy TransferPlatform for Highly Sensitive Detection of Exosomes. Analytical Chemistry 2018, 90(21):12737-12744.
2.Chen, Y.; Liu, X.; Wu, T.; Hou, W.;Liu, M.*; Zhang, Y.; Yao, S. Enhancedelectrochemical sensitivity towards acetaminophen determination usingelectroactive self-assembled ferrocene derivative polymer nanospheres withmulti-walled carbon nanotubes. Electrochimica Acta, 2018, 272: 212-220.
3. Hou, W.; Liu, X.; Lu, Q.; Liu, M.*;Zhang, Y.; Yao,S.Etching and anti-etching strategy forsensitive colorimetric sensing of H2O2and biothiols basedon silver/carbon nanomaterial, Colloids and Surfaces B:Biointerfaces, 2018,162, 118-125.
4. Hou, W.; Chen, Y.; Lu, Q.; Liu, M.*;Zhang, Y.; Yao,S.Silver ions enhanced AuNCs fluorescence as a turn-off nanoprobeforultrasensitive detection of iodide, Talanta,2018, 162, 118-125.
5. Miao, Z.; Hou, W.; Liu, M.; *, Zhang, Y.; Yao, S. BSA cappedbi-functional fluorescent Cu nanoclustersas pH sensor and selective detection of dopamine. New Journal ofChemistry, 2018, 42,1446-1456.
6. Chen, H.; Lu, Q.; He, K.; Liu, M.*; Zhang, Y.*; Yao, S. A cyclicsignal amplification strategy to fluorescence and colorimetric dual-readout assayfor the detection of H2O2-relatedanalytes and applicationto colorimetric logic gate, Sensors and Actuators B, 2018, 260, 908–917.
2017年
1. Wu, Q.; Chen, H.; Fang,A.; Wu, X.; Liu, M.*; Li, H.; Zhang, Y.; Yao, S. A universal multifunctionalnanoplatform based on the target-induced in situ promoting Au seeds growth toquench fluorescence of upconversion nanoparticles. ACS Sens., 2017, 2(12),1805-1813.
2. Zhang,S.; Li, R.; Liu, X.; Yang, L.; Lu, Q.; Liu, M.*; Li, H.; Zhang, Y.;Yao, S., A novel multiple signal amplifying immunosensorbased on the strategy of in situ-produced electroactive substance by ALP andcarbon-based Ag-Au bimetallic as the catalyst and signal enhancer. Biosensorsand Bioelectronics 2017, 92, 457-464.
3. Yang,L.; Huang, N.; Huang, L.; Liu, M.*; Li, H.; Zhang, Y.; Yao, S., Anelectrochemical sensor for highly sensitive detection of copper ions based on anew molecular probe Pi-A decorated on graphene. Analytical Methods 2017, 9 (4),618-624.
4. Fang,A.; Chen, H.; Li, H.; Liu, M.*; Zhang, Y. *; Yao, S., Glutathioneregulation-based dual-functional upconversion sensing-platform for acetylcholinesteraseactivity and cadmium ions. Biosensors and Bioelectronics 2017, 87, 545-551.
5. Chen,Y.; Liu, X.; Zhang, S.; Yang, L.; Liu, M.*; Zhang, Y.; Yao, S., Ultrasensitiveand simultaneous detection of hydroquinone, catechol and resorcinol based onthe electrochemical co-reduction prepared Au-Pd nanoflower/reduced grapheneoxide nanocomposite. Electrochimica Acta 2017, 231,677-685.
2016年
1. Zhang,S.; Liu, X.; Huang, N.; Lu, Q.; Liu, M.*; Li, H.; Zhang, Y.; Yao,S., Sensitive detection of hydrogen peroxide and nitrite based on silver/carbonnanocomposite synthesized by carbondots as reductant via one step method.Electrochimica Acta 2016, 211, 36-43.
2. Zhang,S.; Huang, N.; Lu,Q.; Liu, M.*; Li, H.; Zhang, Y.; Yao, S., Adouble signal electrochemical human immunoglobulin G immunosensor based on goldnanoparticles-polydopamine functionalized reduced graphene oxide as a sensorplatform and AgNPs/carbon nanocomposite as signal probe and catalyticsubstrate. Biosensors and Bioelectronics 2016, 77, 1078-1085.
3. Zhang,L.; Hou, W.; Lu, Q.; Liu, M.*;Chen, C.; Zhang, Y.; Yao, S.,Colorimetric detection of hydrogen peroxide and lactate based on the etching ofthe carbon based Au-Ag bimetallic nanocomposite synthesized by carbon dots asthe reductant and stabilizer. Analytica Chimica Acta 2016, 947, 23-31.
4 Yang,L.; Liu, X.; Lu, Q.; Huang, N.; Liu, M.*; Zhang, Y.; Yao, S., Catalyticand peroxidase-like activity of carbon based-AuPd bimetallic nanocompositeproduced using carbon dots as the reductant. Analytica Chimica Acta 2016, 930,23-30.
5. Yang,L.; Huang, N.; Lu, Q.; Liu, M.*; Li, H.; Zhang, Y.;Yao, S., Aquadruplet electrochemical platform for ultrasensitive and simultaneousdetection of ascorbic acid, dopamine, uric acid and acetaminophen based on aferrocene derivative functional Au NPs/carbon dots nanocomposite andgraphene.Analytica Chimica Acta 2016, 903, 69-80.
6. Fang, A.; Wu, Q.; Chen, H.; Li, H.; Liu,M.*; Zhang, Y. *; Yao, S. Upconversion Ratiometric Fluorescence andColorimetric Dual-Readout Assay for Uric Acid, Biosensors and Bioelectronics2016, 86, 664-670.
2015年
1. Huang,N.; Zhang, S.; Yang, L.; Liu, M.*;Li, H.; Zhang, Y.; Yao, S.,Multifunctional Electrochemical Platforms Based on the Michael Addition/SchiffBase Reaction of Polydopamine Modified Reduced Graphene Oxide: Construction andApplication. ACS Applied Materials &Interfaces 2015, 7 (32), 17935-17946.
2. Huang,N.; Liu, M.*; Li, H.; Zhang, Y.; Yao, S., Synergetic signalamplification based on electrochemical reduced graphene oxide-ferrocenederivative hybrid and gold nanoparticles as an ultra- sensitive detectionplatform for bisphenol A. Analytica Chimica Acta 2015, 853, 249-257.
2. Deng,J.; Lu, Q.; Hou, Y.; Liu, M.*; Li, H.; Zhang, Y.*;Yao, S.,Nanosensor Composed of Nitrogen-Doped Carbon Dots and Gold Nanoparticles forHighly Selective Detection of Cysteine with Multiple Signals. AnalyticalChemistry 2015, 87 (4), 2195-2203.
4 Huang,N.; Liu, M.*; Deng, J.; Wang, L., Zhang, Y.; Yao, S. Fabrication of New GH-CS/Fc-NH2/Cytc Modified Electrodeand ItsApplication in Detection of Nitrite, Chinese Journal of Analytical Chemistry, 43( 3),2015, 325-332.
2014年及以前
1.Liu, M.; Wang, L.; Meng, Y.;Chen, Q.; Li, H.; Zhang, Y.; Yao, S.,(4-Ferrocenylethyne) PhenylamineFunctionalized Graphene Oxide Modified Electrode for Sensitive Nitrite Sensing.Electrochimica Acta 2014, 116,504-511.
2. Liu,C.; Shen, Y.; Yin, P.; Li, L.; Liu, M.; Zhang, Y.; Li, H.;Yao,S., Sensitive detection of acetylcholine based on a novel boronateintra molecularcharge transfer fluorescence probe. Analytical Biochemistry2014, 465, 172-178.
3. Deng,J.; Lu, Q.; Mi, N.; Li, H.; Liu, M.; Xu, M.; Tan, L.; Xie, Q.;Zhang, Y.; Yao, S., Electrochemical Synthesis of Carbon Nanodots Directly fromAlcohols. Chemistry-a European Journal 2014, 20 (17), 4993-4999.
4. Chen,X.; He, Y.; Zhang, Y.; Liu, M.; Liu, Y.; Li, J., Ultrasensitivedetection of cancer cells and glycan expression profiling based on amultivalent recognition and alkaline phosphatase-responsive electrogenerated chemiluminescencebiosensor. Nanoscale 2014, 6 (19), 11196-11203.
5. Chen,Q.; Liu, M.; Zhao, J.; Peng, X.; Chen, X.; Mi, N.; Yin, B.; Li, H.;Zhang, Y.; Yao, S., Water-dispersible silicon dots as a peroxidase mimetic forthe highly-sensitive colorimetric detection of glucose. ChemicalCommunications2014, 50 (51), 6771-6774.
6. Zhao,J.; Liu, M.; Zhang, Y.; Li, H.; Lin, Y.; Yao, S., Apoferritinprotein nanoparticles dually labeled with aptamer and horseradish peroxidase asa sensing probe for thrombin detection. Analytica Chimica Acta 2013, 759,53-60.
7. Liu,M.; Deng, J.; Chen, Q.; Huang, Y.; Wang, L.; Zhao, Y.; Zhang, Y.; Li, H.;Yao, S., Sensitive detection of rutin with novel ferrocene benzyne derivativemodified electrodes. Biosensors & Bioelectronics 2013, 41,275-281.
8. Liu,M.; Chen, Q.; Lai, C.; Zhang, Y.; Deng, J.; Li, H.; Yao, S., A doublesignal amplification platform for ultrasensitive and simultaneous detection ofascorbic acid, dopamine, uric acid and acetaminophen based on a nanocompositeof ferrocene thiolate stabilized Fe3O4@Au nanoparticleswith graphene sheet. Biosensors & Bioelectronics 2013, 48, 75-81.
9. Deng,J.; Liu, M.; Lin, F.; Zhang, Y.; Liu, Y.; Yao, S.,Self-assembled oligo(phenyleneethynylene)s/graphene nanocomposite with improvedelectrochemical performances for dopamine determination. Analytica ChimicaActa2013, 767, 59-65.
10. Liu,M.; Wang, L.; Deng, J.; Chen, Q.; Li, Y.; Zhang, Y.; Li, H.; Yao,S., Highlysensitive and selective dopamine biosensor based on a phenylethynyl ferrocene/graphenenanocomposite modified electrode. Analyst 2012, 137 (19),4577-4583.
11. Liu,M.; Deng, J.; Lai, C.; Chen, Q.; Zhao, Q.; Zhang, Y.; Li, H.; Yao,S.,Synthesis, characterization of conjugated oligo-phenylene-ethynylenes and theirsupramolecular interaction with beta-cyclodextrin for salicylaldehy dedetection.Talanta 2012, 100, 229-238.
12 Luo,J.;Dong, M.; Lin, F.; Liu, M.; Tang, H.; Li, H.; Zhang, Y.; Yao,S., Three-dimensional network polyamidoamine dendrimer-Au nanocomposite for theconstruction of a mediator-free horseradish peroxidase biosensor. Analyst2011,136 (21), 4500-4506.
13 Yang,Q.; Zhang, Y.; Li, H.; Zhang, Y.; Liu, M.; Luo, J.; Tan, L.;Tang,H.; Yao, S., Electrochemical copolymerization study of o-toluidine and o-aminophenolby the simultaneous EQCM and in situ FTIR spectroelectrochemisty. Talanta 2010,81 (1-2), 664-672.
14. Luo,J.; Liu, M.; Zhao, Q.; Zhao, J.; Zhang, Y.; Tan, L.; Tang, H.; Xie,Q.; Li,H.; Yao, S., A study on the electro-oxidation and electropolymerizationof anew OPE linear molecule by EQCM and in situ FTIR spectroelectrochemistry. ElectrochimicaActa2010, 56 (1), 454-462.
15. Liu,M.; Zhang, Y.; Chen, Y.; Xie, Q.; Yao, S., EQCM and in situ FTIR spectroelectrochemistrystudy on the electrochemical oxidation of TMB and the effect of large-sizedanions. Journal of Electroanalytical Chemistry 2008, 622(2), 184-192.
16. 劉美玲, 駱姣, 張友玉, 姚守拙. 現場壓電紅外反射光譜電化學研究鄰聯甲苯胺的電化學行為[J]. 分析化學,2008,09:1172-1176.
17. Zhang,Y.-Y.; Wang, M.-L.; Liu, M.-L.; Yang, Q.; Xie, Q.-J.; Yao, S.-Z.,Growth and properties of poly-o-aminophenol films with three dimensionalcombination of in situ electrochemical quartz crystal microbalance and Fouriertransform infrared spectrolectrochemisty. Chinese Journal of AnalyticalChemistry 2007, 35 (5), 685-690.
18. Zhang,Y.; Liu, M.; Wang, M.; Xie, Q.; Yao, S., In situ monitoring Nielectrodeposition and stripping on gold electrode surface in a static magneticfield using an electrochemical quartz crystal impedance system. Sensors andActuators B-Chemical 2007, 123 (1), 444-453.
19. Zhang,Y.; Liu, M.; Wang, M.; Xie, Q.; Yao, S., In situ monitoring Ni electrodepositionand stripping on gold electrode surface in a static magnetic field using anelectrochemical quartz crystal impedance system. Sensors and ActuatorsB-Chemical 2007, 123 (1), 444-453.
20 Yang,Q.; Zhang, Y.; Liu, M.; Zhang, Y.; Yao, S., Study of fibrinogen adsorptionon hydroxyapatite and TiO2 surfaces by electrochemical piezoelectric quartzcrystal impedance and FTIR-ATR spectroscopy. Analytica Chimica Acta 2007, 597(1), 58-66.
21. Xie,Q.; Li, Z.; Deng, C.; Liu, M.; Zhang, Y.; Ma, M.;Xia, S.; Xiao, X.;Yin, D.; Yao, S., Electrochemical quartz crystal microbalance monitoring of thecyclic voltammetric deposition of polyaniline -A laboratory experiment forundergraduates. Journal of Chemical Education 2007,84 (4), 681-684.
22. Deng,C.; Li, M.; Xie, Q.; Liu, M.; Yang, Q.; Xiang, C.;Yao, S.,Construction as well as EQCM and SECM characterizations of a novel Nafion/glucoseoxidase-glutaraldehyde/poly(thionine)/Au enzyme electrode for glucose sensing.Sensors and Actuators B-Chemical 2007, 122 (1), 148-157.
23. Liu,M. L.; Zhang, Y. Y.; Wang, M. L.; Deng, C. Y.; Xie, Q. J.; Yao, S. Z., Adsorptionof bovine serum albumin and fibrinogen on hydrophilicity-controllable surfacesof polypyrrole doped with dodecyl benzenesulfonate - A combined piezoelectricquartz crystal impedance and electrochemical impedance study. Polymer 2006, 47(10), 3372-3381.
24. Liu,M.; Zhang, Y.; Yang, Q.; Xie, Q.; Yao, S., Monitoring and estimationof the kinetics parameters in the binding process of tannic acid to bovine serumalbumin with electrochemical quartz crystal impedance system. Journal ofAgricultural and Food Chemistry 2006, 54 (12), 4087-4094.
25. Liu,M.; Ye, M.; Yang, Q.; Zhang, Y.; Xie, Q.; Yao, S., A new method for characterizingthe growth and properties of polyaniline and poly(aniline-co-o-aminophenol)films with the combination of EQCM and in situ FTIR spectroelectrochemisty.Electrochimica Acta 2006, 52 (1), 342-352.
26. Li, Y. L.; Liu, M.L.; Xiang, C. H.; Xie, Q. J.; Yao, S. Z., Electrochemical quartz crystalmicrobalance study on growth and property of the polymer deposit at goldelectrodes during oxidation of dopamine in aqueous solutions. Thin Solid Films2006, 497 (1-2), 270-278.
27. 邱從交,劉美玲*,趙嚴,李海濤. 球狀殼聚糖負載噻二唑樹脂的合成及其吸附性能[J]. 套用化學,2011,06:634-639.
28. 趙嚴,鄧建輝,劉美玲*,李海濤,張友玉. 二茂鐵乙炔苯巰基化合物的合成及電化學性質[J]. 套用化學,2011,10:1161-1166.
29. 邱從交,劉美玲*,李海濤. 親水性氨基吡啶樹脂的合成及其吸附性能[J]. 套用化學,2010,09:1042-1045.
30. 趙強欽,劉美玲,駱姣,李海濤,張友玉. 一類新型共軛芳炔二胺的合成及其光電性質[J]. 合成化學,2009,06:665-66
獲獎記錄
1. “碳、矽納米材料及其複合物的合成及分析套用”,湖南省自然科學二等獎（排名第二）,2018年。
2.湖南省自然科學優秀論文一等獎，湖南省科技廳，2015.6。
3. 基於新型對亞苯基亞乙炔基衍生物的小分子化學/生物感測研究. 湖南省優秀博士論文獎，2015年。
4. 劉美玲. 基於新型對亞苯基亞乙炔基衍生物的小分子化學/生物感測研究. 湖南師範大學優秀博士論文. 2013年.
5. 劉美玲. 電化學石英晶體阻抗及現場紅外光譜在生物和聚合物系中的套用研究. 湖南省優秀碩士論文獎, 2008年.
