何瑋毅

何瑋毅，博士，福建農林大學副教授。

基本介紹

• 中文名：何瑋毅
• 畢業院校：福建農林大學
• 學位/學歷：博士
• 職稱：福建農林大學副教授

工作經歷

2014/01 - 至今，福建農林大學，植物保護學院，副教授

2012/05 - 2013/12，福建農林大學，植物保護學院，講師

2009/07 - 2012/05，福建農林大學，植物保護學院，博士後

研究方向

1.小菜蛾基因組學與功能基因組

2.小菜蛾與寄主植物的協同進化關係

主持課題

1.國家自然科學基金青年項目（31301677），小菜蛾GSS與SUMF1基因協同回響寄主植物硫苷及其分子基礎，2014/01-2016/12

2.福建省自然科學基金面上項目（2014J01086），小菜蛾GSS基因回響寄主植物硫苷分子機制研究，2014/01-2016/12

3.福建農林大學“校傑出青年科研人才”培養專項基金（xjq201403），小菜蛾遺傳圖譜構建與比較基因組研究，2014/05-2017/04

獲獎情況

1. 尤民生，楊廣，何瑋毅，謝苗，岳震. 2018年度福建省自然科學獎一等獎，小菜蛾基因組的研究. 證書編號：2018-Z-1-004-03.

2. 第十一屆福建省自然科學論文獎，小菜蛾轉錄組揭示其發育和抗藥性機制，2014.08.

獲批專利

1. 何瑋毅，詹東亮，尤民生. 一種轉錄組數據的表達定量方法及系統. 福建農林大學，ZL 2018 1 0551976.6，2021-09-24.

2. 陳瑋，董玉紅，何瑋毅，荊曉東，張玲玲，尤民生. 昆蟲-植物互作生物學觀測簡易裝置. 福建農林大學，ZL 2019 2 0944680.0，2020-06-05.

發表論文

1. Yue Wang, Minsheng You, Weiyi He. 2021. Genome-wide identification and functional characterization of noncoding RNAs (ncRNAs) differentially expressed during insect development. In: Vaschetto L.M. (eds) RNAi Strategies for Pest Management. Methods in Molecular Biology, vol 2360, pp 1-8. Humana, New York, NY.

2. Fei-Ying Yang, Jun-Hui Chen, Qian-Qian Ruan, Bei-Bei Wang, Lu Jiao, Qing-Xuan Qiao, Wei-Yi He, Min-Sheng You. 2021. Fitness comparison of Plutella xylostella on original and marginal hosts using age-stage, two-sex life tables. Ecology and Evolution, 11(14): 9765-9775.

3. Fei-Ying Yang, Hafiz Sohaib Ahmed Saqib, Jun-Hui Chen, Qian-Qian Ruan, Liette Vasseur, Wei-Yi He, Min-Sheng You. 2020. Differential profiles of gut microbiota and metabolites associated with host shift of Plutella xylostella. International Journal of Molecular Sciences, 21: 6283.

4. Minsheng You, Fushi Ke, Shijun You, Zhangyan Wu, Qingfeng Liu, Weiyi He, Simon W. Baxter, Zhiguang Yuchi, Liette Vasseur, Geoff M. Gurr, Christopher M. Ward, Hugo Cerda, Guang Yang, Lu Peng, Yuanchun Jin, Miao Xie, Lijun Cai, Carl J. Douglas, Murray B. Isman, Mark S. Goettel, Qisheng Song, Qinghai Fan, Gefu Wang-Pruski, David C. Lees, Zhen Yue, Jianlin Bai, Tiansheng Liu, Lianyun Lin, Yunkai Zheng, Zhaohua Zeng, Sheng Lin, Yue Wang, Qian Zhao, Xiaofeng Xia, Wenbin Chen, Lilin Chen, Mingmin Zou, Jinying Liao, Qiang Gao, Xiaodong Fang, Ye Yin, Huanming Yang, Jian Wang, Liwei Han, Yingjun Lin, Yanping Lu, Mousheng Zhuang. 2020. Variation among 532 genomes unveils the origin and evolutionary history of a global insect herbivore. Nature Communications, 11: 2321.

5. Wei Chen, Yuhong Dong, Hafiz Sohaib Ahmed Saqib, Liette Vasseur, Wenwu Zhou, Ling Zheng, Yingfang Lai, Xiaoli Ma, Lianyun Lin, Xuejiao Xu, Jianlin Bai, Weiyi He, Minsheng You. 2020. Functions of duplicated glucosinolate sulfatases in the development and host adaptation of Plutella xylostella. Insect Biochemistry and Molecular Biology, 119: 103316.

6. Fei-Ying Yang, Jun-Hui Chen, Qian-Qian Ruan, Hafiz S. A. Saqib, Wei-Yi He, Min-Sheng You. 2019. Mass spectrometry imaging: An emerging technology for the analysis of metabolites in insects. Archives of Insect Biochemistry and Physiology, 103(4): e21643.

7. Ling-ling Zhang, Xiao-dong Jing, Wei Chen, Yue Wang, Jun-han Lin, Ling Zheng, Yu-hong Dong, Li Zhou, Fei-fei Li, Fei-ying Yang, Lu Peng, Liette Vasseur, Wei-yi He, Min-sheng You. 2019. Host plant-derived miRNAs potentially modulate the development of a cosmopolitan insect pest, Plutella xylostella. Biomolecules, 9(10): 602.

8. Lingling Zhang, Xiaodong Jing, Wei Chen, Jianlin Bai, Liette Vasseur, Weiyi He Minsheng You. 2019. Selection of reference genes for expression analysis of plant-derived microRNAs in Plutella xylostella using qRT-PCR and ddPCR. PLoS ONE, 14(8): e0220475.

9. Wei Chen, Feiying Yang, Xuejiao Xu, Uttam Kumar, Weiyi He, Minsheng You. 2019. Genetic control of Plutella xylostella in omics era. Archives of Insect Biochemistry and Physiology, 102(3): e21621.

10. Wei Chen, Yuhong Dong, Lianyun Lin, Hafiz Sohaib Ahmed Saqib, Xiaoli Ma, Xuejiao Xu, Lingling Zhang, Xiaodong Jing, Lu Peng, Yue Wang, Liette Vasseur, Weiyi He, Minsheng You. 2019. Implication for DNA methylation involved in the host transfer of diamondback moth, Plutella xylostella (L.). Archives of Insect Biochemistry and Physiology, 102(2): e21600.

11. Xiao-Li Ma, Wei-Yi He, Ping Wang, Min-Sheng You. 2019. Cell lines from diamondback moth exhibiting differential susceptibility to baculovirus infection and expressing midgut genes. Insect Science, 26(2): 251-262.

12. Xiao-Li Ma, Wei-Yi He, Wei Chen, Xue-Jiao Xu, Wei-Ping Qi, Ming-Min Zou, Yan-Chun You, Simon W. Baxter, Ping Wang, Min-Sheng You. 2018. Structure and expression of sulfatase and sulfatase modifying factor genes in the diamondback moth, Plutella xylostella. Insect Science, 25(6): 946-958.

13. Weiping Qi, Xiaoli Ma, Weiyi He, Wei Chen, Mingmin Zou, Geoff M. Gurr, Liette Vasseur, Minsheng You. 2016. Characterization and expression profiling of ATP-binding cassette transporter genes in the diamondback moth, Plutella xylostella (L.). BMC Genomics, 17: 760.

14. Weiqi Tang, Liying Yu, Weiyi He, Guang Yang, Fushi Ke, Simon W. Baxter, Shijun You, Carl J. Douglas, Minsheng You. 2014. DBM-DB: the diamondback moth genome database. Database, 2014: bat087.

15. Minsheng You, Zhen Yue, Weiyi He, Xinhua Yang, Guang Yang, Miao Xie, Dongliang Zhan, Simon W. Baxter, Liette Vasseur, Geoff M. Gurr, Carl J. Douglas, Jianlin Bai, Ping Wang, Kai Cui, Shiguo Huang, Xianchun Li, Qing Zhou, Zhangyan Wu, Qilin Chen, Chunhui Liu, Bo Wang, Xiaojing Li, Xiufeng Xu, Changxin Lu, Min Hu, John W. Davey, Sandy M. Smith, Mingshun Chen, Xiaofeng Xia, Weiqi Tang, Fushi Ke, Dandan Zheng, Yulan Hu, Fengqin Song, Yanchun You, Xiaoli Ma, Lu Peng, Yunkai Zheng, Yong Liang, Yaqiong Chen, Liying Yu, Younan Zhang, Yuanyuan Liu, Guoqing Li, Lin Fang, Jingxiang Li, Xin Zhou, Yadan Luo, Caiyun Gou, Junyi Wang, Jian Wang, Huanming Yang, Jun Wang. 2013. A heterozygous moth genome provides insights into herbivory and detoxification. Nature Genetics, 45(2): 220-225.

16. Wei-yi He, Xiao-jing Chen, Liette Vasseur, Yan-hong Shen, Bing-guo Lu and Dong Liang. 2013. Identification of a β-galactosidase fruit pulp-specific promoter and its use in silencing constructs to reduce fruit softening in papaya. African Journal of Biotechnology, 12(18): 2427-2436.

17. Weiyi He, Minsheng You, Liette Vasseur, Guang Yang, Miao Xie, Kai Cui, Jianlin Bai, Chunhui Liu, Xiaojing Li, Xiufeng Xu, Shiguo Huang. 2012. Developmental and insecticide-resistant insights from the de novo assembled transcriptome of the diamondback moth, Plutella xylostella. Genomics, 99(3): 169–177.

18. 李飛飛，王貝貝，賴穎芳，楊菲穎，尤民生，何瑋毅. 2021. fl(2)d單等位基因的敲除顯著降低小菜蛾的生殖力和育性. 中國農業科學，54(14): 3029-3042.

19. 徐雪嬌, 何瑋毅, 楊婕, 陳瑋, 尤民生. 2019. 害蟲遺傳防控技術的研究與套用. 中國科學: 生命科學, 49(8): 938-950.

20. 董玉紅, 陳瑋, 鄭玲, 荊曉東, 周立, 張玲玲, 李曉桐, 何瑋毅. 2018. 小菜蛾飼料品系轉食寄主植物的適合度及其硫苷代謝相關基因表達. 福建農業學報, 33(1): 54-60.

21. 馬小麗, 何瑋毅, 尤民生. 2017. 取食十字花科植物的植食性昆蟲與寄主植物硫苷的互作. 昆蟲學報, 60(9): 1093-1104.

22. 陳瑋, 徐雪嬌, 陳楠菁, 何瑋毅, 尤民生. 2015. 昆蟲DNA甲基化的研究進展. 套用昆蟲學報, 52(5): 1082-1093.

23. 董人富, 馬小麗, 陳亞瓊, 戚偉平, 陳瑋, 何瑋毅, 尤民生. 2015. 昆蟲葡萄糖氧化酶的基本特性及功能. 環境昆蟲學報, 37(2): 426-431.

24. 彭露, 何瑋毅, 夏曉峰, 謝苗, 柯富士, 尤士駿, 黃宇萍, 尤民生. 2015. 基因組學時代害蟲治理的研究進展及前景. 套用昆蟲學報, 52(1): 1-22.

25. 戚偉平，馬小麗，何瑋毅，陳瑋，董人富，尤民生. 2014. 節肢動物ABC轉運蛋白及其介導的殺蟲劑抗性. 昆蟲學報，57(6): 729-736.

為共同一作，為通訊作者