任吉存

任吉存，男 ，上海交通大學化學化工學院教授。1994年於武漢大學獲得分析化學專業博士學位。1994年7 月－1996年3 月任湖南師範大學化學系副教授，系副主任，並在湖南醫科大學從事博士後工作。1996 年3 月至2000 年3月在挪威Bergen大學參加歐共體重大基金項目研究。1997年晉升教授。2001年起任上海交通大學化學化工學院教授，博士生導師。

基本介紹

• 中文名：任吉存
• 畢業院校：武漢大學
• 學位/學歷：博士
• 專業方向：單分子（單顆粒）波動光譜與成像、光學探針設計與合成

人物經歷

1978-1981：安慶師範學院化學系，學士
1991-1994：武漢大學化學學院，博士
1994-1996：中南大學湘雅醫學院，博士後
1996-2000：挪威卑爾根大學醫學院，博士後

1982-1991：安慶師範學院化學系，助教，講師
1994-1996：湖南師範大學化學系，副教授
1997-2001：湖南師範大學化學系，教授
2001-2015：上海交通大學化學化工學院，教授

2015 - 上海交通大學，特聘教授

研究方向

1）單分子（單顆粒）波動光譜與成像： 發展單分子（單顆粒）波動光譜與成像新方法，與微流控晶片技術結合，研究活細胞內生物分子、藥物分子的動力學以及分子間（藥物分子與靶標、蛋白-蛋白）的相互作用。

（2）光學探針設計與合成：設計合成新型的納米光學探針和螢光分子探針，發展活細胞內生物分子的標記新方法。

（3）生物分析：基於微流控晶片電泳和納米光學探針標記技術，發展高靈敏度的分析新方法，用於疾病標誌物、環境污染物分析。

科研項目

主持國家自然科學基金重點項目、科學儀器基礎研究項目、面上項目，科技部“863”專項，上海科委重點項目等。參與 “973”計畫項目，國家自然科學基金重點項目，上海市專項等項目。

榮譽獎勵

2016年獲教育部自然科學一等獎

2015年上海交通大學特聘教授

2008年獲教育部自然科學二等獎

學術兼職

Electrophoresis (Wiley), Microchimica Acta (Springer), Journal of Separation Science (Wiley), Methods and Applications inFluorescence (IOP),《分析化學》,《色譜》等雜誌編委, 國際螢光光譜學方法和套用大會（Methods and Applications inFluorescence, MAF)督導委員會委員(Permanent Steering Committee )

教學工作

本科生：《儀器分析》
研究生：《現代儀器分析》

發布論文

Zhixue Du, Jing Yu,Fucai Li,Liyun Deng, Fang Wu, Xiangyi Huang, Jan Bergstrand, Jerker Widengren, Chaoqing Dong* and Jicun Ren* In situ monitoring p53 protein and MDM2 protein interaction in single living cells using single molecule fluorescence spectroscopy, Anal. Chem., 2018, 90, 6144−6151.

Lvping Cai, Liyun Deng, Xiangyi Huang*, Jicun Ren*, Catalytic Chemiluminescence Polymer Dots for Ultrasensitive In Vivo Imaging of Intrinsic Reactive Oxygen Species in Mice, Anal. Chem., 2018, 90, 6929−6935.

Di Su, Chaoqing Dong and Jicun Ren* Quantitative Determination of Telomerase Activity by Combining Fluorescence Correlation Spectroscopy with Telomerase Repeat Amplification Protocol, Anal. Chem., 2018,90, 10006-1013.

Fang Yi, Xiangyi Huang, Jicun Ren, Simple and Sensitive Method for Determination of Protein Kinase Activity Based on Surface Charge Change of Peptide-Modified Gold Nanoparticles As Substrates, Anal. Chem., 2018, 90, 3871−3877.

Bocheng Zhang, Chaoqing Dong and Jicun Ren* Size Distribution of Noble Metal Nanoparticles Characterized by Combing Resonance Light Scattering Correlation Spectroscopy with Maximum Entropy Method ,Anal. Chem., 2017, 89(22), 12609–12616.

Di Su, Chaoqing Dong, and Jicun Ren* Determination of caspase-3 activity and its inhibition constant by combination of fluorescence correlation spectroscopy with a microwell chip,

Anal. Chem., 2017, 89, 9788−9796.

Jinjie Wang, Chaoqing Dong, Jicun Ren* Fluorescence and scattering light cross correlation spectroscopy and its applications in homogeneous immunoassay,Anal. Chem., 2017，89, 5230−5237.

Aidi Zhang, Chaoqing Dong*, and Jicun Ren* Tuning Blinking Behavior of Highly Luminescent Cesium Lead Halide Nanocrystals through Fast Anion-Exchange Reactions, J. Phys. Chem. C, 2017, 121, 13314−13323.

Heng Liu, Chaoqing Dong, Jicun Ren*, Tempo-Spatially Resolved Scattering Correlation Spectroscopy Based on Dark-Field Microscopy and Its Application to Investigate Dynamic Behaviors of Gold Nanoparticles in Live Cells,

J. Am. Chem. Soc., 2014, 136, 2775−2785.

Chaoqing Dong, Heng Liu, Aidi Zhang, Jicun RenControllable Blinking-to-Nonblinking Behavior of Aqueous CdTeS Alloyed Quantum Dots, Chem. Eur. J.2014, 20(7): 1940-1946.

Chaoqing Dong, Heng Liu, Jicun Ren Assessing the blinking state of fluorescent quantum dots in free solution by combining fluorescence correlation spectroscopy with ensemble spectroscopic methods, Langmuir,2014, 30, 12969−12976.

Aidi Zhang, Chaoqing Dong, Heng Liu and Jicun Ren*, Blinking Behavior of CdSe/CdS Quantum Dots Controlled by Alkylthiols as Surface Trap Modifiers, J. Phys. Chem. C, 2013, 117, 24592−24600.

Bocheng Zhang, Tao Lan, Xiangyi Huang, Chaoqing Dong and Jicun Ren*, Sensitive Single Particle Method for Characterizing Rapid Rotational and Translational Diffusion and Aspect Ratio of Anisotropic Nanoparticles and Its Application in Immunoassays Anal. Chem., 2013, 85, 9433−9438.

Xiangyi Huang, Jicun Ren*, Nanoparticle-Based Chemiluminescence Resonance Energy Transfer: A strategy to develop new analytical methods, TrAC：Trends in Analytical Chemistry, 2012, 40, 77-89.

Lingao Ruan, Zhancheng Xu, Tao Lan, Jinjie Wang, Heng Liu, Chaodong Li Chaoqing Dong, Jicun Ren*, Highly Sensitive Method for Assay of Drug-induced Apoptosis Using Fluorescence Correlation Spectroscopy, Anal. Chem., 2012, 84, 7350−7358.

Heng Liu, Chaoqing Dong, Xiangyi Huang, Jicun Ren*, Spatially Resolved Scattering Correlation Spectroscopy Using A Total Internal Reflection (TIR) Configuration , Anal. Chem., 2012, 84, 3561−3567.

Jie Gao, Xiangyi Huang, Heng Liu, Feng Zan, Jicun Ren *, Colloidal stability of gold nanoparticles modified with thiol compounds, bioconjugation and application in cancer cell imaging, Langmuir, 2012, 28, 4464-4471.

Feng Zan, Chaoqing Dong, Heng Liu, Jicun Ren* Experimental studies on blinking behavior of single InP/ZnS quantum dots: Effects of synthetic conditions and UV irradiation, J. Phys. Chem. C, 2012, 116, 3944−3950.

Feng Zan, Jicun Ren* Gas-liquid phase synthesis of highly luminescent InP/ZnS core/shell quantum dots using zinc phosphide as a new phosphorus source, J. Mater. Chem., 2012, 22, 1794-1799.

Hua He, Chao Xie, Jicun Ren*, Non-Bleaching Fluorescence of Gold Nanoparticles and Its Applications in Cancer Cell Imaging, Anal. Chem., 2008, 80, 5951-5957.

Chaoqing Dong, Jiacheng Guo, Liwen Shao, Jicun Ren* Host-guest interaction of chaperonin GroEL and water soluble CdTe QDs and its size selective encapsulation, ChemPhysChem., 2008, 9, 2245-2251.

Huifeng Qian, Chaoqing Dong, Jinliang Peng, Xin Qiu, Yuhong Xu, Jicun Ren*, High Quality and Water-Soluble Near-Infrared Photoluminescent CdHgTe/CdS Quantum Dots Prepared by Adjusting Size and Composition，J. Phys. Chem. C., 2007, 111, 16852-16857.

Kanglin Wang, Xin Qiu, Chaoqing Dong, Jicun Ren*, Single molecule technology for rapid detection of DNA hybridization based on resonance light scattering of gold nanoparticles as probes, ChemBioChem., 2007, 8, 1126-1129.

Chaoqing Dong, Jicun Ren*, On-line investigation of laser-induced aggregation and photo-activation of CdTe quantum dots by fluorescence correlation spectroscopy,J. Phys. Chem. C, 2007, 111, 7918-7923.

Hua He, Huifeng Qian, Chaoqing Dong, Kanglin Wang，Jicun Ren*, Single Nonblinking CdTe Quantum Dots Synthesized in Aqueous Thiopropionic Acid,Angew. Chem. Int. Ed. 2006, 45, 7588-7591.

Xiangyi Huang, Liang Li, Huifeng Qian, Chaoqing Dong, Jicun Ren* A Resonance Energy Transfer between Chemiluminescence Donors and CdTe Quantum Dots Acceptors (CRET), Angew. Chem. Int. Ed., 2006, 45, 5140-5143.

Chaoqing Dong, Huifeng Qian, Nenghu Fang and Jicun Ren*, Study of Fluorescence Quenching and Dialysis Process of CdTe Quantum Dot Using Ensemble Techniques and Fluorescence Correlation Spectroscopy, J. Phys. Chem. B, 2006, 110,11069-11075.

Huifeng Qian, Xing Qiu, Liang Li, Jicun Ren* Microwave assisted aqueous synthesis: a rapid approach to prepare highly luminescent ZnSe(S) alloyed quantum dots, J. Phys. Chem. B, 2006, 110, 9034-9040.

Jifang Weng, Jicun Ren*, Luminescent Quantum Dots: An Attractive Promising Tool in Biomedicine, Current Medicinal Chemistry, 2006, 13, 897-909.

Huifeng Qian, Jicun Ren*, Facile one-pot synthesis of highly luminescent, water-soluble and bio-compatible glutathione coated CdTe quantum Dots in aqueous phase, Small, 2006, 2,747-751.

Xiangyi Huang, Jicun Ren*, Chemiluminescence detection in capillary electrophoresis and microchip capillary electrophoresis, TRAC：Trends in Analytical Chemistry, 2006, 25,155-156.

Chaoqing Dong, Rui Bi, Huifeng Qian, Jicun Ren* Coupling fluorescence correlation Spectroscopy with Microchip Electrophoresis to Determine Effective Surface Charge of Water-Soluble QDs, Small, 2006, 2,534-538.

Liang Li, Huifeng Qian, Jicun Ren*，CdTe@Co(OH)(core/shell) nanoparticles: aqueous synthesis and characterizations,Chemical Communication,2005, 4083-4085.

Liang Li, Huifeng Qian, Jicun Ren*, Rapid Synthesis of Highly Luminescent CdTe Nanocrystals in Aqueous Phase by Microwave Irradiation with Controllable Temperature, Chemical Communication, 2005, 528-530.

Jicun Ren*, Arve Ulvik, Helga Refsum, Per Magne Ueland , Uracil in Human DNA from Subjects with Normal and Impaired Folate Status, as Determined by High Performance Liquid Chromatography-Tandem Mass, Analytical Chemistry, 2002, 74, 295-299.

Jicun Ren*, Xiangyi Huang, Highly Sensitive and Universal Indirect Chemiluminescence Detection for Capillary Electrophoresis of Cations Using Cobalt(II) As A Novel Probe Ion,Analytical Chemistry, 2001, 73, 2663-2668.

出版專著

Jicun Ren, 《Capillary Electrophoresis of Nucleic Acid》, Chapter 10 and Chapter 19, Jan., 2001, Humana Press Inc., Totowa, NJ, USA.