《中國遺傳及地方性疾病資源譜(英文版)》內容為：The book can be used by medical students as a supplementary textbook. It is also of great value as a reference for health professionals and physicians. Multiple copies of this valuable book should also be on the shelves of all universities,medical schools and research establishments where these subjects are studied.
基本介紹
- 書名：中國遺傳及地方性疾病資源譜
- 出版社：科學出版社
- 頁數：302頁
- 開本：16
- 品牌：科學出版社
- 作者：王嵬
- 出版日期：2009年1月1日
- 語種：英語
- ISBN：9787030238795
內容簡介,圖書目錄,序言,
內容簡介
《中國遺傳及地方性疾病資源譜(英文版)》為華夏英才基金學術文庫之一。
圖書目錄
A Brief Introduction
Foreword
Acknowledgements
CHAPTER 1 China and its peoples
1.1 Chinese population demographics
1.2 The Han and the ethnic minorities
1.3 Geographical characteristics
1.4 Population size and growth
1.5 Population age structure
1.6 Migration
1.7 Urbanization
1.8 Marriage patterns
1.9 Fertility patterns(including the One-Child-Family programme)
1.10 Maternal mortality
1.11 Mortality patterns
1.12 Conclusion
References
CHAPTER 2 Single gene disorders
2.1 Introduction
2.2 Amino acid (and/or other) disorders
2.3 Hemoglobinopathies
2.4 The influence of nutritional factors on the expressions of genetic
disorders
2.5 Conclusion
References
CHAPTER 3 Chromosomal disorders
3.1 General overview
3.2 Down syndrome
3.3 Symptoms and comorbidities
3.4 Etiology
3.5 Factors
3.6 Treatments and prevention
3.7 Conclusion
References
CHAPTER 4 Congenital disorders
4.1 Introduction
4.2 Congenital heart disease
4.3 Neural tube defects
4.4 Oral and facial clefts
4.5 Case study:congenital deafness
4.6 Conclusion
References
CHAPTER 5 Psoriasis and eczema
5.1 Introduction
5.2 Epidemiology
5.3 Etiology and pathogenesis
5.4 Symptoms
5.5 Treatments and prevention
5.6 Eczema
5.7 Conclusion
References
CHAPTER 6 Essential epilepsy
6.I Introduction
6.2 Symptoms
6.3 Epidemiology
6.4 Etiology
6.5 Treatment and prevention
6.6 Conclusion
References
CHAPTER 7 Behavioral and psychiatric disorders
7.1 General overview
7.2 Case study 1
7.3 Case study 2
7.4 Conclusion
References
CHAPTER 8 Cardiovascular disease
8.1 Overview
8.2 Case study:hypertension
8.3 Epidemiology
8.4 Cardiovascular disease as the primary cause of death and hyperter
the main simply treatable risk factor
8.5 Etiology
8.6 Treatments and prevention
References
CHAPTER 9 Epidemiology and risk factors of common cancers
9.1 Breast cancer
9.2 Nasopharyngeal carcinoma
9.3 Lung cancer
9.4 Stomach cancer
9.5 Colorectal cancer
9.6 Liver cancer
9.7 Case study:esophageal cancer
References
CHAPTER 10 Dietary deficiency disorders
10.1 Overview
10.2 Iodine deficiency
10.3 Symptoms
10.4 Etiology
10.5 Pathogenesis
10.6 Pathology of endemic goiter
10.7 Prevention and treatments
10.8 Conclusion
10.9 Keshan disease
10.10 Epidemiology
10.11 Pathology
10 12 Etiology
10 13 Pathogenesis
10 14 Clinical and laboratory investigations
10 15 Diagnosis
10.16 Treatment
References
CHAPTER 11 Environmental toxicity disorders
11.1 Endemic fluorosis
11.2 Epidemiology
11.3 Pathology
11.4 Symptoms and stages
11.5 Clinical diagnosis and differential diagnosis
11.6 Prevention
11.7 Conclusion
11.8 Endemic arsenic poisoning
11.9 Epidemiology
11.10 Etiology
11.11 Pathology
11.12 Pathogenesis
11.13 Clinical manifestations
11.14 Clinical diagnosis and differential diagnosis
11.15 Endemic arsenic poisoning prevention and treatment
References
CHAPTER 12 Combined deficiency-toxicity disorders
12.1 Kashin-Beck Disease
12.2 Symptoms
12.3 Geographical distribution
12.4 Population prevalence
12.5 Family occurrence
12.6 Etiology
12.7 Pathology
12.8 Pathogenesis
12.9 Prevention and treatment
12.10 Differential diagnosis
12.11 Conclusion
References
CHAPTER 13 Bioethical and legislative restrictions in China
13.1 Family planning programs
13.2 Eugenics laws and sex selection
13.3 Disabled people and moral protection in China
13.4 Sex ethnic
13.5 Sexually transmitted diseases
13.6 Confucian ethics and the market economy
References
Foreword
Acknowledgements
CHAPTER 1 China and its peoples
1.1 Chinese population demographics
1.2 The Han and the ethnic minorities
1.3 Geographical characteristics
1.4 Population size and growth
1.5 Population age structure
1.6 Migration
1.7 Urbanization
1.8 Marriage patterns
1.9 Fertility patterns(including the One-Child-Family programme)
1.10 Maternal mortality
1.11 Mortality patterns
1.12 Conclusion
References
CHAPTER 2 Single gene disorders
2.1 Introduction
2.2 Amino acid (and/or other) disorders
2.3 Hemoglobinopathies
2.4 The influence of nutritional factors on the expressions of genetic
disorders
2.5 Conclusion
References
CHAPTER 3 Chromosomal disorders
3.1 General overview
3.2 Down syndrome
3.3 Symptoms and comorbidities
3.4 Etiology
3.5 Factors
3.6 Treatments and prevention
3.7 Conclusion
References
CHAPTER 4 Congenital disorders
4.1 Introduction
4.2 Congenital heart disease
4.3 Neural tube defects
4.4 Oral and facial clefts
4.5 Case study:congenital deafness
4.6 Conclusion
References
CHAPTER 5 Psoriasis and eczema
5.1 Introduction
5.2 Epidemiology
5.3 Etiology and pathogenesis
5.4 Symptoms
5.5 Treatments and prevention
5.6 Eczema
5.7 Conclusion
References
CHAPTER 6 Essential epilepsy
6.I Introduction
6.2 Symptoms
6.3 Epidemiology
6.4 Etiology
6.5 Treatment and prevention
6.6 Conclusion
References
CHAPTER 7 Behavioral and psychiatric disorders
7.1 General overview
7.2 Case study 1
7.3 Case study 2
7.4 Conclusion
References
CHAPTER 8 Cardiovascular disease
8.1 Overview
8.2 Case study:hypertension
8.3 Epidemiology
8.4 Cardiovascular disease as the primary cause of death and hyperter
the main simply treatable risk factor
8.5 Etiology
8.6 Treatments and prevention
References
CHAPTER 9 Epidemiology and risk factors of common cancers
9.1 Breast cancer
9.2 Nasopharyngeal carcinoma
9.3 Lung cancer
9.4 Stomach cancer
9.5 Colorectal cancer
9.6 Liver cancer
9.7 Case study:esophageal cancer
References
CHAPTER 10 Dietary deficiency disorders
10.1 Overview
10.2 Iodine deficiency
10.3 Symptoms
10.4 Etiology
10.5 Pathogenesis
10.6 Pathology of endemic goiter
10.7 Prevention and treatments
10.8 Conclusion
10.9 Keshan disease
10.10 Epidemiology
10.11 Pathology
10 12 Etiology
10 13 Pathogenesis
10 14 Clinical and laboratory investigations
10 15 Diagnosis
10.16 Treatment
References
CHAPTER 11 Environmental toxicity disorders
11.1 Endemic fluorosis
11.2 Epidemiology
11.3 Pathology
11.4 Symptoms and stages
11.5 Clinical diagnosis and differential diagnosis
11.6 Prevention
11.7 Conclusion
11.8 Endemic arsenic poisoning
11.9 Epidemiology
11.10 Etiology
11.11 Pathology
11.12 Pathogenesis
11.13 Clinical manifestations
11.14 Clinical diagnosis and differential diagnosis
11.15 Endemic arsenic poisoning prevention and treatment
References
CHAPTER 12 Combined deficiency-toxicity disorders
12.1 Kashin-Beck Disease
12.2 Symptoms
12.3 Geographical distribution
12.4 Population prevalence
12.5 Family occurrence
12.6 Etiology
12.7 Pathology
12.8 Pathogenesis
12.9 Prevention and treatment
12.10 Differential diagnosis
12.11 Conclusion
References
CHAPTER 13 Bioethical and legislative restrictions in China
13.1 Family planning programs
13.2 Eugenics laws and sex selection
13.3 Disabled people and moral protection in China
13.4 Sex ethnic
13.5 Sexually transmitted diseases
13.6 Confucian ethics and the market economy
References
序言
Genetic disorders are commonly found in every community and endemicdiseases are restected in specific geographical areas in China. Traditionally recognized hereditary disorders in the form of chromosomal, single gene and complexmedical diseases have a prevalence of about 20%-25%. If acquired genetic disor-ders and somatic genetic disorders such as cancer are included, the prevalence iseven higher. Given the huge burden of genetic disorders on patients, families andthe community,it is essential to study their mechanisms and bring forth powerfulpreventive measures. To effectively control the genetic disorders and endemic dis-eases in China, the first priority is the systematic collection of basic data such asprevalence of various disorders and endemic diseases, contributing factors, andvariations in expression among different ethnic groups and the general population. However,until now there has been no Chinese books or scientific journalsaddressing this issue.
This book collects those information mentioned above and discusses in detail,the most commonly found multigene genetic disorders, single gene genetic disorders and chromosomal genetic disorders among Chinese,and also the endemic diseases in different parts of China. The choice of the disorders in this book wasbased on published Chinese epidemiological data. The emphasis of this book isfocused on the disease prevalence, in different populations and regions home andabroad, the trend of alterations of prevalence,and a brief introduction to the pres-ent status of research and therapy available in China and in the world. Geneticdisorders and endemic diseases in minority groups in China, genetic studies inisolated and semiisolated communities of Chinese, and major influencing factorsare also discussed.
This book collects those information mentioned above and discusses in detail,the most commonly found multigene genetic disorders, single gene genetic disorders and chromosomal genetic disorders among Chinese,and also the endemic diseases in different parts of China. The choice of the disorders in this book wasbased on published Chinese epidemiological data. The emphasis of this book isfocused on the disease prevalence, in different populations and regions home andabroad, the trend of alterations of prevalence,and a brief introduction to the pres-ent status of research and therapy available in China and in the world. Geneticdisorders and endemic diseases in minority groups in China, genetic studies inisolated and semiisolated communities of Chinese, and major influencing factorsare also discussed.
