《Gene Therapy of Cancer》是一本圖書，作者是Lattime, Edmund C.; Gerson, Stanton L.;
基本介紹
- ISBN：9780123942951
- 作者：Lattime, Edmund C.; Gerson, Stanton L.;
- 出版時間：2013年8月
- 頁數：559
- 定價：$ 225.94
內容簡介
The third edition of Gene Therapy of Cancer provides crucial updates on the basic and applied sciences of gene therapy. It offers a comprehensive assessment of the field, including the areas of suicide gene therapy, oncogene and suppressor gene targeting, immunotherapy, drug resistance gene therapy, and the genetic modification of stem cells. Researchers at all levels of develo...(展開全部) The third edition of Gene Therapy of Cancer provides crucial updates on the basic and applied sciences of gene therapy. It offers a comprehensive assessment of the field, including the areas of suicide gene therapy, oncogene and suppressor gene targeting, immunotherapy, drug resistance gene therapy, and the genetic modification of stem cells. Researchers at all levels of development, from basic laboratory investigators to clinical practitioners, will benefit from this book. Cancer gene therapy is evolving rapidly, testing new concepts, targets and pathways, evoking new technologies, and passing new regulatory hurdles. With the ultimate goal of returning altered genes to normal, gene therapy for cancer can, in some instances, form a continuum from gene repair through: the use of molecularly modified cells; the use of viral and non-viral vector-based gene delivery to both tumor and tumor microenvironment; the use of viral and gene based vaccines; and development of new gene-based therapeutics. This volume considers these unique mechanistically chosen vector platforms in depth, because they allow for direct and selective cell death and transient to sustained delivery of vaccine molecules or molecules that affect the microenvironment, vasculature, or the immune response. Gene therapy as a treatment for cancer is at a critical point in its evolution. Exciting new developments in gene targeting and vector technology, coupled with results from the first generation of preclinical and clinical studies have led to the design and testing of these promising new therapeutic app
