Alberto Pablo Macho Escribano

Alberto Pablo Macho Escribano，青年千人計畫/研究員。

簡歷：

2004年：西班牙馬拉加大學，生物學學士; 2006年：西班牙馬拉加大學，生物技術碩士; 2010年：西班牙馬拉加大學，遺傳學博士; 2010年08月-2011年01月：西班牙馬拉加大學，博士後; 2011年02月-2014年12月：英國諾維奇塞恩斯伯里實驗室，博士後; 2015年01月-至今：中國科學研究院上海植物逆境生物學研究中心，研究員

研究方向：

植物與細菌病原體之間的相互作用

職稱：

研究員

職務：

研究組長、博士生導師

獲獎及榮譽：

2015年 入選中央“青年千人計畫”

代表論著：

Segonzac C., Macho A.P., Sanmartín M., Ntoukakis V., Sánchez-Serrano J.J. and Zipfel C. Negative control of BAK1 by Protein Phosphatase 2A during plant innate immunity. EMBO Journal (2014) online early: DOI: 10.15252/embj.201488698; Macho A.P. and Zipfel C. Plant PRRs and the activation of innate immune signaling. Molecular Cell (2014) 54: 263-272.; Macho A.P.*, Schwessinger, B.*, Ntoukakis V.*, Brutus A., Segonzac C., Roy S., Kadota Y., Oh M-H., Sklenar J., Derbyshire P., Lozano-Durán R., Gro Malinovsky F., Monaghan J., Menke F.L., Huber S.C., He S.Y. and Zipfel C. (* Co-first authors) A bacterial tyrosine phosphatase inhibits plant pattern recognition receptor activation. Science (2014) 343: 1509-1512.; Lozano-Durán R., Macho A.P., Boutrot F., Segonzac C., Somssich I. and Zipfel C. The transcriptional regulator BZR1 mediates trade-off between plant innate immunity and growth. eLife (2013) 2:e00983.; Sun Y., Li L., Macho A.P., Han Z., Hu Z., Zipfel C., Zhou J.M. and Chai J.J. Structural basis for flg22-induced activation of the Arabidopsis FLS2-BAK1 immune complex. Science (2013) 342: 624-628.; Macho A.P., Boutrot F., Rathjen J.P. and Zipfel C. Aspartate Oxidase plays an important role in Arabidopsis stomatal immunity. Plant Physiology (2012) 159 (4): 1845-56.; Macho A.P.*, Zumaquero A.*, González-Plaza J.J., Ortiz-Martín I., Rufián J.S. and Beuzón C.R. Genetic analysis of the individual contribution to virulence of the type III effector inventory of Pseudomonas syringae pv. phaseolicola. (* Co-first authors) PLoS One (2012) 7 (4): e35871.; Macho A.P. and Beuzón, C.R. Insights into plant immunity signaling: The bacterial competitive index angle. Plant Signaling & Behavior (2010) 5, 1-4.; Zumaquero, A., Macho, A.P., Rufián, J.S. and Beuzón, C.R. Approaching the role of the type III effector inventory of Pseudomonas syringae pv. phaseolicola 1448a in the interaction with the plant. Journal of Bacteriology (2010) 192 (17): 4474-4488.; Macho A.P., Guevara C.M., Tornero P., Ruiz-Albert J. and Beuzón C.R. The Pseudomonas syringae type III effector HopZ1a suppresses effector-triggered immunity. New Phytologist (2010) 187 (4): 1018-1033.; Macho A.P.*, Guidot A.*, Barberis P., Beuzón C.R. and Genin S. A competitive index assay identifies several Ralstonia solanacearum Type III effector mutant strains with reduced fitness in host plants. (* Co-first authors) Molecular Plant-Microbe Interactions (2010) 23 (9): 1197–1205.; Ortiz-Martín I., Thwaites R., Macho A.P., Mansfield J.W. and Beuzón C.R. Positive regulation of the Hrp type III secretion system in Pseudomonas syringae pv. phaseolicola. Molecular Plant-Microbe Interactions (2010) 23 (5): 665-681.; Macho A.P., Ruiz-Albert J., Tornero P. and Beuzón C.R. Identification of new type III effectors and analysis of the plant response by competitive index. Molecular Plant Pathology (2009) 10 (1): 69-80.; Rodríguez-Moreno L., Pineda M., Soukupová J., Macho, A.P., Beuzón C.R., Barón M., Ramos C. Early detection of bean infection by Pseudomonas syringae in asymptomatic leaf areas using chlorophyll fluorescente imaging. Photosynthesis research (2008) 96 (1): 27-35.; Macho A.P., Zumaquero A., Ortiz-Martín I., and Beuzón C.R. Competitive index in mixed infections: a sensitive and accurate assay for the genetic analysis of Pseudomonas syringae-plant interactions. Molecular Plant Pathology (2007) 8 (4): 437–450.