龐珊珊，男，重慶大學生命科學學院博士生導師，百人計畫特聘教授。
基本介紹
- 中文名：龐珊珊
- 畢業院校：美國南加州大學
- 學位/學歷：博士
- 專業方向：代謝與衰老生物學
- 職務：重慶大學生命科學學院博士生導師
- 職稱：教授
人物經歷,研究方向,發表論文,
人物經歷
2000 - 2004 四川大學， 學士
2004 - 2010 上海生命科學研究院，博士
2011 - 2014 美國南加州大學，博士後
2014 - 至今 重慶大學“百人計畫”教授，博士生導師
研究方向
代謝與衰老生物學。衰老是生命發展的必經階段，衰老與許多慢性疾病的產生，如癌症，肥胖和二型糖尿病等，有著密切的關係，這些疾病因此也可以稱為衰老相關性疾病。本研究組以模式動物研究為基礎，致力於解析衰老的遺傳和代謝機制，並以此為基礎探索延緩衰老及治療衰老相關疾病的途徑。
發表論文
1. Tang H, Pang S. Proline catabolism modulates innate immunity in C. elegans. Cell Reports 17(11): 2837-2844. (2016)
2. Pang S, Lynn D, Lo J, Curran SP. SKN-1 and Nrf2 couples proline catabolism with lipid metabolism during nutrient deprivation. Nature Communications 5:5048. (2014).
3. Pang S, Curran SP. Adaptive capacity to bacterial diet modulates aging in C. elegans. Cell Metabolism 19(2): 221-231. (2014). (Previewed as a leading edge finding in Cell Metabolism 19(2): 177-178, 2014)
4. Pang S, Curran SP. Longevity and the long arm of epigenetics: acquired parental marks influence lifespan across several generations. Bioessays 34(8): 652-654. (2012)
5. Zhang L, Pang S, Deng B, Qian L, Chen J, Zou J, Zheng J, Yang L, Zhang C, Chen X, Liu Z, Le Y. High glucose induces renal mesangial cell proliferation and fibronectin expression through JNK/NF-κB/NADPH oxidase/ROS pathway, which is inhibited by resveratrol. Int J Biochem Cell Biol 44: 629-638. (2012)
6. Pang S, Tang H, Zhuo S, Zang YQ and Le Y. Regulation of fasting fuel metabolism by Toll-like receptor 4. Diabetes 59: 3041-3048. (2010)
7. Tang H, Pang S, Wang M, Xiao X, Rong Y, Wang H, Zang YQ. TLR4 activation is required for IL-17-induced multiple tissue inflammation and wasting in mice. J Immunol 185: 2563-2569. (2010)
8. Wang O, Cai K, Pang S, Wang T, Qi D, Zhu Q, Ni Z, Le Y. Mechanisms of glucose-induced expression of pancreatic-derived factor in pancreatic beta-cells. Endocrinology.149:672-680. (2008)
9. Pang S, Le Y. Role of resistin in inflammation and inflammation-related diseases. Cell Mol Immunol 3:29-34. (2006)
