馮麗恆,1979年生,山西交城人,工學博士,教授,博士生導師。
現任山西大學化學化工學院副院長。
基本介紹
- 中文名:馮麗恆
- 出生日期:1979年
- 畢業院校:山西大學
- 學位/學歷:博士
- 職業:教師
- 專業方向:功能材料分子及生物套用
人物經歷,社會兼職,研究方向,獲獎記錄,主持科研項目,代表性論文,授權專利,
人物經歷
2014/12 – 至今,山西大學,化學化工學院,教授
2012/03 – 2014/02,中國科學院化學研究所,博士後
2009/10 – 2014/11,山西大學,化學化工學院,副教授
2007/07 – 2009/09,山西大學,化學化工府轎捉槳學院,講師
2002/09 – 2007/06,山西大學,化學化工學院,博士(碩博連讀)
1998/09 – 2002/06,山西大學,化學化工學院,學士
現任山西大學化學化工學院副院長,山西大學校學術委員會委員,化學學科分學術委員會副主任委員,教師第一黨支部支部書記。
社會兼職
中國化學學會委員,山西省納米醫藥組委會委員,山西省生物工程學會精準醫療與伴隨診斷專委會委員。
研究方向
有機共軛分子材料的制鑽記拒備及套用研究。提出了解決抗菌耐藥性關鍵科學問題的新策略;發展了徹底治癒惡性腫瘤的新技術;闡明了惡性腫瘤難以徹底治癒的根源;明確了病詢整故原菌耐藥性的作用機制;揭示了有機付抹功能分子與細菌、腫瘤細胞相互作用的方式;搭建了自組裝體多功能藥物向臨床套用初步探索的橋樑。
獲獎記錄
“青年三晉學者”特聘教授,山西省高等學校中青年拔尖人才,山西省高等學校優秀青年學術帶頭人,“131”工程中青年拔尖人才及“三晉英才”優秀青年人才。
曾獲得山西省自然科學二等獎,山西省優宙樂歸秀博士論文獲得者。
主持科研項目
1、 國家自然科學基金(面上項目), 2020.1-2023.12
2、 國家自然科學基金(面上項目), 2016.1-2019.12;
3、國家自然科學基金(面上項目), 2014.1-2017.12;
4、國家自然科學基金(青年), 2009.1-2011.12;
5、“三晉學者特聘教殃局懂臭授”專項基金,2018.1-2022.12;
6、山西青高等學校中青年拔尖人才專項基金,2017.7-2020.12;
7、山西省優秀青年科技基金,2014.1-2016.12;
8、山西省高等學校優秀青年學術帶頭人專項基金,騙旋櫻2013.5-2016.5;
9、中國博士後科學基金特別資助,2013.1-2014;
10、中國博士後科學面上二等資助,2012.6-2013.6;
11、山西省自然科學基金(青年),2009.1-2011.12;
代表性論文
1. Liheng Feng, Chunlei Zhu, Huanxiang Yuan, Libing Liu*, FengtingLv, Shu Wang*, Conjugated Polymer Nanoparticles: Preparation, Properties, Functionalization and Biological Applications, Chem. Soc. Rev., 2013, 42, 6620. IF=40.44
2. Liheng Feng, Libing Liu, Fengting Lv, Guollermo C. Bazan*, Shu Wang*, Preparation and Biofunctionalization of Multicolor Conjugated Polymer Nanoparticles for Imaging and Detection of Tumor Cells, Adv. Mater., 2014, 26, 3926. IF=25.81
3. Yunxia Wang, Shengliang Li*, Pengbo Zhang, Haotian Bai, Liheng Feng, Fengting Lv, Libing Liu*, Shu Wang*, Photothermal-responsive Conjugated Polymer Nanoparticles for Remote Control of Gene Expression in Living Cells, Adv. Mater., 2018, 1705418. IF=25.81
4. Fengyan Wang, Zhang Liu, Bing Wang, Liheng Feng, Libing Liu*, Fengting Lv, Yilin Wang*, Shu Wang*, Multi-color Fibers by Self-assembly of DNA, Histone Proteins and Cationic Conjugated Polymers, Angew. Chem. Int. Ed., 2014, 53, 424. IF=12.26
5. Jinzhao Song, Jiangyan Zhang, Fengting Lv*, Yongqiang Cheng, Bing Wang, Liheng Feng, Libing Liu, Shu Wang*, Multiplex Detection of DNA Mutations by Fluorescence Fingerprint Spectrum Technique, Angew. Chem. Int. Ed., 2013, 52, 3020. IF=12.26
6. Yunxia Wang, Liheng Feng*, Shu Wang*, Conjugated Polymer Nanoparticles for Imaging, Cell Activity Regulation, and Therapy, Adv. Funct. Mater., 2019, 29, 1806818. IF=15.62
7. Meng Li, Liheng Feng, Haiyan Lu,* Shu Wang,* Chuanfeng Chen*, Tetrahydro[5]helicene-Based Nanoparticles for Structure-Dependent Cell Fluorescent Imaging, Adv. Funct. Mater., 2014, 24, 4405. IF=15.62
8. Liheng Feng*, Lixia Guo, Xiaoju Wang*, Preparation, Properties and Applications in Cell Imaging and Ions Detection of Conjugated Polymer Nanoparticles with Alcoxyl Bonding Fluorene Core, Biosens. Bioelectron., 2017, 87, 514. IF=9.52
9. Lixia Guo, Haoping Wang, Yunxia Wang,* Feng Liu,* Liheng Feng*, Organic Polymer Nanoparticles with Primary Ammonium Salt as Potent Antibacterial Nanomaterials ACS Appl. Mater. Interfaces, 2020, DOI. 10.1021/acsami.9b19921. IF=8.46
10. Yunxia Wang, Haoping Wang, Lixia Guo, Yuehong Pang,* Liheng Feng*, Red Fluorescence Conjugated Polymer with Broad Spectrum Antimicrobial Activity for Treatment of Bacterial Infections in Vivo, ACS Appl. Mater. Interfaces, 2018, 10, 34878. IF=8.46
11. Liheng Feng*, Jiarong Zhu, Zhijun Wang*, Biological Functionalization of Conjugated Polymer Nanoparticles for Targeted Imaging and Photodynamic Killing of Tumor Cells, ACS Appl. Mater. Interfaces, 2016, 8, 19364. IF=8.46
12. Yunxia Wang, Shengliang Li, Liheng Feng, Chenyao Nie, Libing Liu,* Fengting Lv, and Shu Wang*, Fluorescence Ratiometric Assay Strategy for Chemical Transmitter of Living Cells Using H2O2Sensitive Conjugated Polymers, ACS Appl. Mater. Interfaces, 2015, 7, 24110. IF=8.46
13. Chenyao Nie, Chunlei Zhu, Liheng Feng, Fengting Lv*, Libing Liu, Shu Wang*, Synthesis of a New Conjugated Polymer for DNA Alkylation and Gene Regulation, ACS Appl. Mater. Interfaces, 2013, 5, 4549. IF=8.46
14. Lixia Guo, Haoping Wang, Yunxia Wang*, Liheng Feng*, Tailor-Made Polymer Nano-Assembly with Switchable Function and Amplified Anti-Tumor Therapy, Adv. Healthc. Mater., 2019, 9, 1901492. IF=6.27
15. Sirong Zhou, Changgang Yang, Lixia Guo, Yunxia Wang*, Guofeng Zhang*, Liheng Feng*, Water-soluble Conjugated Polymer with Near-infrared Absorption for Synergistic Tumor Therapy Using Photothermal and Photodynamic Activity, Chem. Comm., 2019, 55, 8615. IF=6.16
16. Zhenkang Wen,* Zekai Zhao, Ningjing Wang, Ziling Chen, Jianbin Chao, Liheng Feng*, Palladium-Catalyzed Controllable Reductive/Oxidative Heck Coupling between Cyclic Enones and Thiophenes via C−H Activation, Org. Lett., 2019, 21, 9545. IF=6.55
17. Lixia Guo, Haoping Wang, Yunxia Wang*, Liheng Feng*, Facile Core–shell Nanoparticles with Controllable Antibacterial Activity Assembled by Chemical and Biological Molecules, Biomater. Sci., 2019, 7, 5528. IF=5.25
18. Haoping Wang, Lixia Guo, Yunxia Wang*, Liheng Feng*, Bactericidal Activity-tunable Conjugated Polymers as a Human-friendly Bactericide for the Treatment of Wound Infections, Biomater. Sci., 2019, 7, 3788. IF=5.25
19. Sirong Zhou, Zhijun Wang, Yunxia Wang,* Liheng Feng*, Near-Infrared Light-Triggered Synergistic Phototherapy for Antimicrobial Therapy, ACS Appl. Bio Mater., 2020, 3, 1730.
20. Yunxia Wang, Shengliang Li, Libing Liu,* Liheng Feng*, Photothermal-Responsive Conjugated Polymer Nanoparticles for the Rapid and Effective Killing of Bacteria, ACS Appl. Bio Mater., 2018, 1, 27.
授權專利
1. 馮麗恆, 郭麗霞. 一種環狀聚合物及其製備方法和套用,中國發明專利,授 權日2020.2.14,專利號:ZL201810189654.1
2. 馮麗恆, 王皓萍. 一種光動力殺菌聚合物及其製備方法和套用,中國發明專利,授權日2020.1.3,專利號:ZL201810189651.8
3. 馮麗恆, 鄧楊.一種紅光發射聚合物及製備方法,中國發明專利,授權日2018.4.24,專利號:ZL201610552452.X
4. 馮麗恆,殷寧華,王曉菊. 一種檢測連翹酯苷A的組合物及其製備方法,中國發明專利,授權日2017.12.5,專利號:ZL201510169890.3
5. 馮麗恆, 郭麗霞. 一種藍光發光材料及其製備方法,中國發明專利,授權日2017.11.3,專利號:ZL20161020923.0
6. 王曉菊, 趙三虎, 張立偉, 馮麗恆. 一種雙核苯並咪唑離子鹽及其製備方法和套用,中國發明專利,授權日2016.9.28,專利號:ZL201510005233.5
7. 王曉菊, 魏超飛, 馮麗恆. 一種3-(溴代苯基)-2,2’-二氟丙酸的製備方法,中國發明專利,授權日2016.5.11,專利號:ZL201510005147.4
8. 李猛, 王樹, 馮麗恆, 陳傳峰. 有機螢光染料分子及其合成方法和套用, 中國發明專利,授權日2015.10.28,專利號:ZL20161020923.0
9. 刁海鵬, 劉文, 馮麗恆, 解軍. 一種6-氨基-5-氟-1-異吲哚啉酮的製備方法,中國發明專利,授權日2014.1.15,專利號,ZL201210421516.4
10. 馮麗恆,孫玥,牛偉平,梁飛. 2-氰基-5-氨基嘧啶的製備方法,中國發明專利,授權日2013.2.23,專利號:ZL201110169997.X
11. 馮麗恆,段煉,王越,徐明,殷寧華. 一種檢測D-果糖的組合物及其製備方法,中國發明專利,授權日2013.1.2,專利號:ZL201110166960.1
12. 趙三虎,王曉菊,牛偉平,馮麗恆. 一種含有蒽功能團的水溶性聚合物及其製備方法,中國發明專利,授權日2012.12.5,專利號,ZL201110279953.2
13. 陳兆斌,馮麗恆. 一種含有電子注入傳輸基團的金屬絡合物型發光材料及其製備方法,中國發明專利,授權日2006.12.6,專利號:ZL200410012447.4
14. 馮麗恆,陳兆斌. 一種含有空穴傳輸基團的金屬絡合物型發光材料及其製備方法,中國發明專利,授權日2006.7.12,專利號:ZL200410012446.2
2. Liheng Feng, Libing Liu, Fengting Lv, Guollermo C. Bazan*, Shu Wang*, Preparation and Biofunctionalization of Multicolor Conjugated Polymer Nanoparticles for Imaging and Detection of Tumor Cells, Adv. Mater., 2014, 26, 3926. IF=25.81
3. Yunxia Wang, Shengliang Li*, Pengbo Zhang, Haotian Bai, Liheng Feng, Fengting Lv, Libing Liu*, Shu Wang*, Photothermal-responsive Conjugated Polymer Nanoparticles for Remote Control of Gene Expression in Living Cells, Adv. Mater., 2018, 1705418. IF=25.81
4. Fengyan Wang, Zhang Liu, Bing Wang, Liheng Feng, Libing Liu*, Fengting Lv, Yilin Wang*, Shu Wang*, Multi-color Fibers by Self-assembly of DNA, Histone Proteins and Cationic Conjugated Polymers, Angew. Chem. Int. Ed., 2014, 53, 424. IF=12.26
5. Jinzhao Song, Jiangyan Zhang, Fengting Lv*, Yongqiang Cheng, Bing Wang, Liheng Feng, Libing Liu, Shu Wang*, Multiplex Detection of DNA Mutations by Fluorescence Fingerprint Spectrum Technique, Angew. Chem. Int. Ed., 2013, 52, 3020. IF=12.26
6. Yunxia Wang, Liheng Feng*, Shu Wang*, Conjugated Polymer Nanoparticles for Imaging, Cell Activity Regulation, and Therapy, Adv. Funct. Mater., 2019, 29, 1806818. IF=15.62
7. Meng Li, Liheng Feng, Haiyan Lu,* Shu Wang,* Chuanfeng Chen*, Tetrahydro[5]helicene-Based Nanoparticles for Structure-Dependent Cell Fluorescent Imaging, Adv. Funct. Mater., 2014, 24, 4405. IF=15.62
8. Liheng Feng*, Lixia Guo, Xiaoju Wang*, Preparation, Properties and Applications in Cell Imaging and Ions Detection of Conjugated Polymer Nanoparticles with Alcoxyl Bonding Fluorene Core, Biosens. Bioelectron., 2017, 87, 514. IF=9.52
9. Lixia Guo, Haoping Wang, Yunxia Wang,* Feng Liu,* Liheng Feng*, Organic Polymer Nanoparticles with Primary Ammonium Salt as Potent Antibacterial Nanomaterials ACS Appl. Mater. Interfaces, 2020, DOI. 10.1021/acsami.9b19921. IF=8.46
10. Yunxia Wang, Haoping Wang, Lixia Guo, Yuehong Pang,* Liheng Feng*, Red Fluorescence Conjugated Polymer with Broad Spectrum Antimicrobial Activity for Treatment of Bacterial Infections in Vivo, ACS Appl. Mater. Interfaces, 2018, 10, 34878. IF=8.46
11. Liheng Feng*, Jiarong Zhu, Zhijun Wang*, Biological Functionalization of Conjugated Polymer Nanoparticles for Targeted Imaging and Photodynamic Killing of Tumor Cells, ACS Appl. Mater. Interfaces, 2016, 8, 19364. IF=8.46
12. Yunxia Wang, Shengliang Li, Liheng Feng, Chenyao Nie, Libing Liu,* Fengting Lv, and Shu Wang*, Fluorescence Ratiometric Assay Strategy for Chemical Transmitter of Living Cells Using H2O2Sensitive Conjugated Polymers, ACS Appl. Mater. Interfaces, 2015, 7, 24110. IF=8.46
13. Chenyao Nie, Chunlei Zhu, Liheng Feng, Fengting Lv*, Libing Liu, Shu Wang*, Synthesis of a New Conjugated Polymer for DNA Alkylation and Gene Regulation, ACS Appl. Mater. Interfaces, 2013, 5, 4549. IF=8.46
14. Lixia Guo, Haoping Wang, Yunxia Wang*, Liheng Feng*, Tailor-Made Polymer Nano-Assembly with Switchable Function and Amplified Anti-Tumor Therapy, Adv. Healthc. Mater., 2019, 9, 1901492. IF=6.27
15. Sirong Zhou, Changgang Yang, Lixia Guo, Yunxia Wang*, Guofeng Zhang*, Liheng Feng*, Water-soluble Conjugated Polymer with Near-infrared Absorption for Synergistic Tumor Therapy Using Photothermal and Photodynamic Activity, Chem. Comm., 2019, 55, 8615. IF=6.16
16. Zhenkang Wen,* Zekai Zhao, Ningjing Wang, Ziling Chen, Jianbin Chao, Liheng Feng*, Palladium-Catalyzed Controllable Reductive/Oxidative Heck Coupling between Cyclic Enones and Thiophenes via C−H Activation, Org. Lett., 2019, 21, 9545. IF=6.55
17. Lixia Guo, Haoping Wang, Yunxia Wang*, Liheng Feng*, Facile Core–shell Nanoparticles with Controllable Antibacterial Activity Assembled by Chemical and Biological Molecules, Biomater. Sci., 2019, 7, 5528. IF=5.25
18. Haoping Wang, Lixia Guo, Yunxia Wang*, Liheng Feng*, Bactericidal Activity-tunable Conjugated Polymers as a Human-friendly Bactericide for the Treatment of Wound Infections, Biomater. Sci., 2019, 7, 3788. IF=5.25
19. Sirong Zhou, Zhijun Wang, Yunxia Wang,* Liheng Feng*, Near-Infrared Light-Triggered Synergistic Phototherapy for Antimicrobial Therapy, ACS Appl. Bio Mater., 2020, 3, 1730.
20. Yunxia Wang, Shengliang Li, Libing Liu,* Liheng Feng*, Photothermal-Responsive Conjugated Polymer Nanoparticles for the Rapid and Effective Killing of Bacteria, ACS Appl. Bio Mater., 2018, 1, 27.
授權專利
1. 馮麗恆, 郭麗霞. 一種環狀聚合物及其製備方法和套用,中國發明專利,授 權日2020.2.14,專利號:ZL201810189654.1
2. 馮麗恆, 王皓萍. 一種光動力殺菌聚合物及其製備方法和套用,中國發明專利,授權日2020.1.3,專利號:ZL201810189651.8
3. 馮麗恆, 鄧楊.一種紅光發射聚合物及製備方法,中國發明專利,授權日2018.4.24,專利號:ZL201610552452.X
4. 馮麗恆,殷寧華,王曉菊. 一種檢測連翹酯苷A的組合物及其製備方法,中國發明專利,授權日2017.12.5,專利號:ZL201510169890.3
5. 馮麗恆, 郭麗霞. 一種藍光發光材料及其製備方法,中國發明專利,授權日2017.11.3,專利號:ZL20161020923.0
6. 王曉菊, 趙三虎, 張立偉, 馮麗恆. 一種雙核苯並咪唑離子鹽及其製備方法和套用,中國發明專利,授權日2016.9.28,專利號:ZL201510005233.5
7. 王曉菊, 魏超飛, 馮麗恆. 一種3-(溴代苯基)-2,2’-二氟丙酸的製備方法,中國發明專利,授權日2016.5.11,專利號:ZL201510005147.4
8. 李猛, 王樹, 馮麗恆, 陳傳峰. 有機螢光染料分子及其合成方法和套用, 中國發明專利,授權日2015.10.28,專利號:ZL20161020923.0
9. 刁海鵬, 劉文, 馮麗恆, 解軍. 一種6-氨基-5-氟-1-異吲哚啉酮的製備方法,中國發明專利,授權日2014.1.15,專利號,ZL201210421516.4
10. 馮麗恆,孫玥,牛偉平,梁飛. 2-氰基-5-氨基嘧啶的製備方法,中國發明專利,授權日2013.2.23,專利號:ZL201110169997.X
11. 馮麗恆,段煉,王越,徐明,殷寧華. 一種檢測D-果糖的組合物及其製備方法,中國發明專利,授權日2013.1.2,專利號:ZL201110166960.1
12. 趙三虎,王曉菊,牛偉平,馮麗恆. 一種含有蒽功能團的水溶性聚合物及其製備方法,中國發明專利,授權日2012.12.5,專利號,ZL201110279953.2
13. 陳兆斌,馮麗恆. 一種含有電子注入傳輸基團的金屬絡合物型發光材料及其製備方法,中國發明專利,授權日2006.12.6,專利號:ZL200410012447.4
14. 馮麗恆,陳兆斌. 一種含有空穴傳輸基團的金屬絡合物型發光材料及其製備方法,中國發明專利,授權日2006.7.12,專利號:ZL200410012446.2