項楠，男，2009年6月獲浙江大學學士學位，2014年12月獲東南大學博士學位，現為東南大學機械工程學院教授、博士生導師。
所負責的微流控課題組一直從事新型微型化醫療儀器、創新即時診斷設備、微機電系統產品和軟體仿生機器人的設計與製造，以及其所涉及精密加工、微操控和精準檢測基礎科學問題的研究。
基本介紹
人物簡介,榮譽及獲獎,研究方向,科研項目,科研成果,著作,論文,專利,社會任職,
人物簡介
項楠教授，江蘇省優青，江蘇省優博，東南大學首批“至善青年學者”（A層次），江蘇省“六大人才高峰”高層次人才。
2021年4月－，東南大學，機械工程學院，教授/博導
2017年11月－2021年3月，東南大學，機械工程學院，副教授/博導
2015年1月－2017年10月，東南大學，機械工程學院，講師
2009年9月－2014年12月，東南大學，機械製造及其自動化，研究生/博士
2005年9月－2009年6月，浙江大學，本科/學士
以上參考
榮譽及獲獎
2021年，江蘇省優秀碩士學位論文指導教師
2021年，Journal of Visualized Experiments期刊Methods Collections“Microfluidic cell manipulation”的客座編輯
2020年，英國皇家化學學會Outstanding reviewer for Lab on a Chip
2020年，英國物理學會IOP Publishing Top Cited Paper Award
2019年，江蘇省優青
2018年，東南大學首批“至善青年學者”（A層次）
2018年，International Conference of Microfluidics, Nanofluidics and Lab-on-a-Chip分會場主席
2019年，The 6th ASME Micro/Nanoscale Heat & Mass Transfer International Conference子專題組織者及分會場主席
2017年，Nanotechnology 封面研究被英國物理學會專題報導
2017年，江蘇省“六大人才高峰”高層次人才計畫
2016年，江蘇省優秀博士學位論文
2018年，南京市第十二屆自然科學優秀學術論文一等獎
2016年，東南大學優秀博士學位論文
2016年，中泰國立獎教金三等獎
2013年和2012年，研究生國家獎學金
以上參考
研究方向
1. 新型醫療器械產品的設計與製造； 2. 微機電系統及微型化儀器； 3. 超精密製造技術； 4. 微型化軟體仿生機器人及套用
科研項目
主持國家自然科學面上/青年基金、江蘇省優青等科研或人才項目7項，以排名第二參研國家自然科學重大科研儀器研製項目等國家級科研項目4項。
項目名稱 | 項目類別 | 項目時間 | 項目金額（萬元） |
|---|---|---|---|
基於電指紋差異的循環腫瘤細胞精準檢測晶片研究 | 國家自然科學基金委員會（面上） | 2019-2022 | 60 |
微流控儀器的設計與製造 | 江蘇省科技廳（優青） | 2019-2022 | 50 |
面向稀有循環腫瘤細胞的非標記精準檢測儀器研製 | 國家自然科學基金委員會（重大儀器） | 2018-2022 | 690 |
全血中稀有循環腫瘤細胞的精準表征方法研究 | 國家自然科學基金委員會（面上） | 2018-2021 | 62 |
形變和形狀特性對生物粒子慣性遷移行為的影響機理研究 | 國家自然科學基金委員會（青年） | 2016-2018 | 26 |
複雜特性生物細胞慣性聚焦機理及其套用研究 | 江蘇省科技廳（青年） | 2015-2018 | 20 |
以上參考
科研成果
著作
Nan Xiang, Zhonghua Ni. Inertial Microfluidics for Single-Cell Manipulation and Analysis.In: Santra T., Tseng FG. (eds) Handbook of Single Cell Technologies. Springer, Singapore (參編圖書章節)
論文
在Lab on a Chip (IF 6.799)、Analytical Chemistry (IF 6.986)及Science Bulletin (IF 11.780)等知名期刊發表SCI論文86篇（JCR Q1/Q2區71篇, IF>5的25篇）。
Shu Zhu, Yaohui Fang, Yao Chen, Peiwen Yu, Yu Han, Nan Xiang*, Zhonghua Ni*. Stackable Micromixer with Modular Design for Efficient Mixing over Wide Reynold Numbers, International Journal of Heat and Mass Transfer, 2022, 183:122129 (SCI，IF=5.584) Fengtao Jiang, Nan Xiang*. Series and parallel integration of flow regulators for precise and multiple-output fluid delivery，Sensors and Actuators: A. Physical, 2021, 332:113160 (SCI，IF=3.407) Cailian Wang*, Yan Chen, Xuyu Gu, Xiuxiu Zhang, Chanchan Gao, Lijun Dong, Shiya Zheng, Shicheng Feng, Nan Xiang*. Low-cost polymer-film spiral inertial microfluidic device for label-free separation of malignant tumor cells, Electrophoresis, 2021, DOI: https://doi.org/10.1002/elps.202100232 (SCI，IF=3.535) Nan Xiang*, Zhonghua Ni*. Electricity-free hand-held inertial microfluidic sorter for size-based cell sorting, Talanta, 2021, 235: 122807 (SCI，IF=6.057) Zheng Zhou, Yao Chen, Shu Zhu, Linbo Liu, Zhonghua Ni, Nan Xiang*. Inertial microfluidics for high-throughput cell analysis and detection: a review, Analyst, 2021, 146: 6064–6083 (SCI，IF=4.616) Nan Xiang*, Silin Wang, Zhonghua Ni*. Secondary-flow-aided single-train elastic-inertial focusing in low elasticity viscoelastic fluids, Electrophoresis, 2021, 42: 2256–2263 (SCI，IF=3.535) Shu Zhu, Xiaozhe Zhang, Mu Chen, Dezhi Tang, Yu Han, Nan Xiang*, Zhonghua Ni*.An easy-fabricated and disposable polymer-film microfluidic impedance cytometer for cell sensing, Analytica Chimica Acta, 2021, 1175: 338759 (SCI，IF=6.558) 張孝哲, 項楠*,倪中華. 單細胞機械性能檢測方法與套用研究進展, 生物物理和生物化學進展, 2021, DOI: http://www.pibb.ac.cn/pibbcn/ch/reader/view_abstract.aspx?flag=2&file_no=202104280000001&journal_id=pibbcn (SCI) Shu Zhu, Xiaozhe Zhang, Zheng Zhou, Yu Han, Nan Xiang*, Zhonghua Ni*. Microfluidic impedance cytometry for single-cell sensing: review on electrode configurations. Talanta, 2021, 233: 122571 (SCI，IF=6.057) Zhixian Zhu, Dan Wu, Shuang Li, Yu Han, Nan Xiang*, Cailian Wang, Zhonghua Ni*. A polymer-film inertial microfluidicsorter fabricated by jigsaw puzzle method for precise size-based cellseparation. Analytica Chimica Acta, 2021, 1143:306-314 (SCI，IF=6.558) Dezhi Tang, Mu Chen, Yu Han*, Nan Xiang*, Zhonghua Ni*. Asymmetric serpentine microchannel based impedance cytometerenabling consistent transit and accurate characterization of tumor cells and bloodcells. Sensors & Actuators: B. Chemical, 2021, 336:129719 (SCI，IF=7.46) Hui Ren, Zhixian Zhu, Nan Xiang*, HaoWang, Tingting Zheng, Hongjie An, Nam-Trung Nguyen*, Jun Zhang*. Multiplexedserpentine microchannels for high-throughput sorting of disseminated tumorcells from malignant pleural effusion. Sensors & Actuators: B. Chemical, 2021, 337:129758 (SCI，IF=7.46) Di Huang, Nan Xiang*. Rapid andprecise tumor cell separation using the combination of size-dependent inertialand sizeindependent magnetic methods. Lab on a Chip, 2021, 21(7):1409-1417 (SCI，IF=6.799) Di Jiang, Chen Ni, Wenlai Tang*, Nan Xiang*. Numerical simulation of elasto-inertial focusing of particles instraight microchannels.Journalof Physics D: Applied Physics, 2021, 54:065401 (SCI，IF=3.207) Nan Xiang*, Zhonghua Ni*. Deformability cytometry for high-throughput cell mechanical phenotyping. Science Bulletin, 2020, 65(24):2045-2047 (SCI IF=11.78) Nan Xiang*, Qiao Li, Zhonghua Ni*. Combining Inertial Microfluidics with Cross-Flow Filtration for High-Fold and High-Throughput Passive VolumeReduction. Analytical Chemistry, 2020, 92(9):6770-6776 (SCI，IF=6.986) Wenlai Tang, Shu Zhu, Di Jiang, Liya Zhu, Jiquan Yang, Nan Xiang*. Channel innovations for inertial microfluidics. Lab on a Chip, 2021, 20: 3485-3502 (SCI，IF=6.799) Shu Zhu, Dan Wu, Yu Han, Cailian Wang, Nan Xiang*, Zhonghua Ni*. Inertial microfluidic cube for automatic and fast extraction of white blood cells from whole blood. Lab on a Chip, 2020, 20(2):244-252 (SCI，IF=6.799) Nan Xiang*, Qiao Li, Zhiguo Shi, Chenguang Zhou, Fengtao Jiang, Yu Han,Zhonghua Ni*. Low-cost multi-core inertial microfluidic centrifuge forhigh-throughput cell concentration. Electrophoresis, 2020, 41(10-11):875-882 (SCI，IF=3.535) Linbo Liu, Haoyan Xu, Haibo Xiu, Nan Xiang*, Zhonghua Ni*. Microfluidicon-demand engineering of longitudinal dynamic self-assembly of particles. Analyst,2020, 145:5128-5133 (SCI，IF=4.616) Shu Zhu, Fengtao Jiang, Yu Han, Nan Xiang*, Zhonghua Ni*. Microfluidics for label-free sorting of rarecirculating tumor cells. Analyst 2020, 145(22): 7103-7124. (SCI，IF=4.616) Di Huang, Jiaxiang Man, Di Jiang, Jiyun Zhao, Nan Xiang*. Inertial microfluidics: Recent advances. Electrophoresis,2020, 41, 2166–2187 (SCI，IF=3.535) Fengtao Jiang, Nan Xiang*, ZhonghuaNi*. Ultrahigh throughput beehive-like device for blood plasma separation. Electrophoresis, 2020, 41(13): 2136–2143. (SCI，IF=3.535) Yunlin Quan, Ke Chen, Nan Xiang*,Zhonghua Ni*. A single-view field filter device for rare tumor cell filtrationand enumeration. Electrophoresis, 2020, 41(23):2000-2006. (SCI，IF=3.535) Linbo Liu, Nan Xiang*, Zhonghua Ni*. Droplet-based microreactor for the production ofmicro/nano-materials. Electrophoresis, 2020, 41(10-11):833-851 (SCI，IF=3.535) Nan Xiang*, Rui Zhang, YuHan, Zhonghua Ni*. A Multilayer Polymer-Film Inertial Microfluidic Device for High-Throughput Cell Concentration. Analytical Chemistry, 2019, 91(8):5461-5468 (SCI，IF=6.986) Nan Xiang*, Yu Han, Yuan Jia, Zhiguo Shi, Hong Yi, Zhonghua Ni*.Flow stabilizer on a syringe tip for hand-powered microfluidic sample injection. Lab on a Chip, 2019, 19(2): 214-222(SCI，IF=6.799) Nan Xiang*, Jie Wang, Qiao Li, Yu Han, Di Huang*, Zhonghua Ni*. Precise Size-Based Cell Separation via the Coupling of Inertial Microfluidics and Deterministic Lateral Displacement. Analytical Chemistry, 2019, 91(15):10328-10334 (SCI，IF=6.986) Xinjie Zhang, Kang Xia, Aimin Ji, Nan Xiang*. A smart and portable micropump for stable liquid delivery. Electrophoresis, 2019, 40(6): 865-872 (SCI，IF=3.535) Jingwen Mo*, Yaohuan Ding,Shu Zhu, Pan Kuang, Long Shen, Nan Xiang*,Jingjie Sha, Yunfei Chen*. Passive microscopic fluidic diodes using asymmetricchannels. AIP Advances, 2019, 9(8):085117 (SCI，IF=1.548) Linbo Liu, Ke Chen, Nan Xiang*, Zhonghua Ni*. Dielectrophoretic manipulation of nanomaterials: a review. Electrophoresis, 2019, 40(6): 873-889 (SCI，IF=3.535) Nan Xiang*, Qing Dai, Yu Han, Zhonghua Ni*. Circular-channel particlefocuser utilizing viscoelastic focusing. Microfluidics and Nanofluidics, 2019, 23(2):16 (SCI，IF=2.529) Wenlai Tang*, Di Jiang, Zongan Li, Liya Zhu, Jianping Shi, JiquanYang, Nan Xiang*. Recent advances in microfluidic cell sorting techniques based on both physical and biochemicalprinciples. Electrophoresis, 2019, 40(6): 930-945 (SCI，IF=3.535) Wenlai Tang, Ning Fan, Jiquan Yang, Zongan Li, Liya Zhu, Di Jiang, Jianping Shi*, Nan Xiang*.Elasto-inertial particle focusing in 3D-printed microchannels withunconventional cross sections.Microfluidics and Nanofluidics, 2019, 23(3):42 (SCI，IF=2.529) Di Jiang, Di Huang, Gutian Zhao, Wenlai Tang*, Nan Xiang*. Numerical simulation of particle migration in different contraction–expansion ratio microchannels. Microfluidicsand Nanofluidics, 2019, 23(1), 7 (SCI，IF=2.529) Nan Xiang*, Xin Shi, Yu Han, Zhiguo Shi, Fengtao Jiang, Zhonghua Ni*. Inertial Microfluidic Syringe Cell Concentrator. Analytical Chemistry, 2018, 90(15): 9515–9522 (SCI，IF=6.986) Nan Xiang*, Zhonghua Ni, Hong Yi*. Concentration‐controlled particle focusing inspiral elasto‐inertial microfluidic devices. Electrophoresis, 2018, 39(2): 417-424(SCI，IF=3.535) Xinjie Zhang, Zhixian Zhu, Nan Xiang*, Feifei Long, Zhonghua Ni*. Automated microfluidic instrument for label-free and high-throughput cell separation.Analytical Chemistry, 2018,90(6): 4212–4220 (SCI，IF=6.986) Xin Wang, Ke Chen, Linbo Liu, Nan Xiang*, ZhonghuaNi*. Dielectrophoresis-based multi-stepnanowire assembly on a flexible superstrate. Nanotechnology, 2018, 29(2):025301 (SCI，IF=3.874) Wenlai Tang, Dezhi Tang, Zhonghua Ni, Nan Xiang*, Hong Yi*. Microfluidic impedance cytometer with inertial focusing and liquid electrodes for high-throughput cell counting and discrimination. Analytical Chemistry, 2017, 89(5):3154-3161(SCI，IF=6.986) Linbo Liu, Ke Chen*, Di Huang, Xin Wang, Nan Xiang*, Zhonghua Ni. A novel ‘leadless’dielectrophoresis chip with dot matrix electrodes for patterning nanowires.Nanotechnology, 2017, 28(28):285302(SCI，IF=3.874) Xinjie Zhang, Zhixian Zhu, Zhonghua Ni, Nan Xiang*, Hong Yi*. Inexpensive, rapidfabrication of polymer-film microfluidic autoregulatory valve for disposablemicrofluidics. Biomedical Microdevices, 2017, 19(2):21 (SCI，IF=2.838) Wenlai Tang, Dezhi Tang, Zhonghua Ni, Nan Xiang*, Hong Yi*. A portable single-cell analysis system integrating hydrodynamic trapping with broadband impedance spectroscopy. Science ChinaTechnological Sciences, 2017, 60(11):1707-1715 (SCI，IF=3.572) Nan Xiang*, Qing Dai, Zhonghua Ni*.Multi-train elasto-inertial particle focusing in straight microfluidicchannels. Applied Physcis Letters,2016, 109(13):134101 (SCI，IF=3.791) Xinjie Zhang, Zhixian Zhu, Nan Xiang*,Zhonghua Ni*. A microfluidic gas damper for stabilizing gas pressure inportable microfluidic systems.Biomicrofluidics,2016, 10(5):054123 (SCI，IF=2.8) Nan Xiang*, Xinjie Zhang, Qing Dai, Jie Cheng, Ke Chen, Zhonghua Ni*. Fundamentals ofelasto-inertial particle focusing in curved microfluidic channels. Lab on a Chip, 2016, 16(14):2626-2635(SCI，IF=6.799) Nan Xiang*, Di Huang, Jie Cheng, KeChen, Xinjie Zhang, Wenlai Tang, Zhonghua Ni*. Focusing dynamics offinite-sized particles in confined microfluidic channels. Applied Physics Express, 2016, 9(2):027001 (SCI，IF=2.895) Di Huang, Xin Shi, Yi Qian, Wenlai Tang, Linbo Liu, Nan Xiang*, Ni Zhonghua*. Rapid separation of human breast cancer cells from blood using a simple spiral channel device. Analytical Methods, 2016, 8(30): 5940-5948 (SCI，IF=2.896) Di Jiang, Wenlai Tang, Nan Xiang*, ZhonghuaNi*. Numerical simulation of particle focusing in a symmetrical serpentine microchannel. RSC Advances, 2016,6(62): 57647-57657 (SCI，IF=3.361) Xinjie Zhang, Xin Wang, Ke Chen, Jie Cheng, Nan Xiang*, Zhonghua Ni*.Passive flow regulator for precise high-throughput flow rate control in microfluidic environments. RSC Advances, 2016, 6(38): 31639-31646 (SCI，IF=3.361) Xinjie Zhang, Di Huang, Wenlai Tang, Di Jiang, Ke Chen, Hong Yi, Nan Xiang*, Zhonghua Ni*. A low cost and quasi-commercial polymerfilm chip for high-throughput inertial cell isolation. RSC Advances, 2016, 6(12): 9734-9742 (SCI，IF=3.361) Nan Xiang*, Zhonghua Ni.High-throughput blood cell focusing and plasma isolation using spiral inertialmicrofluidic devices. Biomedical Microdevices, 2015, 17(6): 110-121 (SCI，IF=2.838) Nan Xiang, Zhiguo Shi, Wenlai Tang, DiHuang, Xinjie Zhang, Zhonghua Ni*. Improved understanding of particle migrationmodes in spiral inertial microfluidic devices. RSC Advances, 2015,5(94): 77264-77273 (SCI，IF=3.361) XinjieZhang#, Nan Xiang#(共同一作), Wenlai Tang, Di Huang, XinWang, Hong Yi, Zhonghua Ni*. A passive flow regulator with low threshold pressure for high-throughput inertial isolation of microbeads. Lab on a Chip, 2015, 15(17): 3473-3480 (SCI，IF=6.799) Nan Xiang, Ke Chen, Qing Dai, Di Jiang, Dongke Sun, Zhonghua Ni*. Inertia-induced focusing dynamics of microparticles throughout a curved microfluidic channel. Microfluidics and Nanofluidics, 2015, 18(1): 29-39 (SCI，IF=2.529) Nan Xiang, Hong Yi, Ke Chen, DongkeSun, Di Jiang, Qing Dai, Zhonghua Ni*. High-throughput inertial particlefocusing in a curved microchannel: Insights into the flow-rate regulation mechanism and process model. Biomicrofluidics, 2013, 7(4): 044116(SCI，IF=2.8) Nan Xiang, Hong Yi, Ke Chen, ShanfangWang, Zhonghua Ni*. Investigation of the maskless lithography technique for therapid and cost-effective prototyping of microfluidic devices in laboratories. Journal of Micromechanics and Microengineering, 2013, 23(2): 025016 (SCI，IF=1.881) Nan Xiang, Ke Chen, Dongke Sun, Shanfang Wang, Hong Yi, ZhonghuaNi*. Quantitative characterization of the focusing process and dynamic behaviorof differently sized microparticles in a spiral microchannel. Microfluidicsand Nanofluidics, 2013, 14(1-2): 89-99 (SCI，IF=2.529) Nan Xiang, Xiaolu Zhu, Zhonghua Ni*.Application of Inertial Effect in Microfluidic Chips. Progress in Chemistry, 2011, 23(9): 1945-1958 (SCI，IF=1.172) |
以上參考
專利
系列研究成果總計申請發明專利58項，其中已授權28項，申請PCT國際專利4項。
社會任職
擔任JoVE期刊和Biosensors的客座編輯，擔任40餘個國際學術期刊的審稿人，當選Outstanding reviewer for Lab on a Chip（2021）。
