軟界面上分子相互作用與成像分析研究

《軟界面上分子相互作用與成像分析研究》是邵元華為項目負責人,北京大學為依託單位的青年科學基金項目。

基本介紹

  • 中文名:軟界面上分子相互作用與成像分析研究
  • 項目類別:重點項目
  • 依託單位:北京大學
  • 項目負責人:邵元華
科研成果,項目摘要,

科研成果

序號
標題
類型
作者
1
微、納米級液/液界面上的電荷轉移過程
會議論文
朱新宇|喬永輝|邵元華|李箐|趙文博|劉書娟|紀天容|
2
納米級液/液界面上的快速離子轉移反應的動力學研究
會議論文
邵元華|李箐|
3
利用掃描離子電導顯微鏡探測硝基苯/水界面結構
會議論文
朱新宇|紀天容|邵元華|
4
石墨烯/離子液體凝膠修飾玻碳電極對多巴胺,抗壞血酸和尿酸的同時檢測
會議論文
謝翔|邵元華|
5
不同親水性探針分子在金電極上硫醇自組裝跨膜動力學研究
期刊論文
陳忠|沈麗|何莎莉|謝書寶|邵元華|靜平|徐曉東|
6
軟界面上分子相互作用與成像分析
會議論文
邵元華|
7
Constructive Nanolithography by Chemically Modified Tips: Nanoelectrochemical Patterning on SAMs/Au
期刊論文
Zheng, Zhikun|Yang, Menglong|Zhang, Bailin|
8
Anion Transfer at a Micro-Water/1,2-Dichloroethane Interface Facilitated by beta-Octafluoro-meso-octamethylcalix[4]pyrrole
期刊論文
Yang, Ronghua|Shao, Yuanhua|Meng, Xin|Sessler, Jonathan L.|Li, Qing|Li, Bo|Cui, Renfa|Gross, Dustin E.|
9
界面分子相互作用電化學、掃描隧道顯微鏡和微懸臂研究
期刊論文
張柏林|
10
Study on the Electrochemistry of a Na(3)[Ti(2)P(2)O(10)F]center dot xH(2)O-Modified Glassy Carbon Electrode
期刊論文
Miao, Xiaopei|Hu, Jingbo|Li, Meixian|Li, Guobao|Zhu, Zhiwei|Shao, Yuanhua|
11
電化學方法製備原子尺度間隙的 Au隧道結過程研究
期刊論文
夏勇|張柏林|董曉東|朱果逸|
12
An i-DNA based electrochemical sensor for proton detection
期刊論文
Shao, Yuanhua|Li, Xiaohui|Xie, Xiang|Xu, Xiaodong|Li, Bo|Shen, Li|
13
In Situ Scanning Tunneling Microscopy on the Dynamic Process of the Replacement of Coronene on Au (111) by 6-Mercapto-1-Hexanol
期刊論文
Zhang, Bailin|Wu, Sanhua|
14
Electrochemical sensor for melamine based on its copper complex
期刊論文
Li, Meixian|Zhu, Hong|Zhang, Songxin|Zhu, Zhiwei|Shao, Yuanhua|
15
微懸臂生物感測器檢測生物素-親和素相互作用
期刊論文
潘宏青|張慧勇|唐紀琳|張柏林|
16
The adsorption of dopamine on gold and its interactions with iron(III) ions studied by microcantilevers
期刊論文
Xia, Yong|Zhang, Bailin|Xu, Yingming|WU, Sanhua|
17
Electrochemical synthesis of a ferrocenecarboxylic acid–C60 composite and its electrocatalysis to hydrogen peroxide
期刊論文
Sun, Baoyun|Hu, Jingbo|Li, Meixian|Wang, Shukuan|Miao, Xiaopei|Liu, Lu|Lin, Hong|
18
Kinetics of Heterogeneous Electron Transfer Reactions at the Externally Polarized Water/o-Nitrophenyl Octyl Ether Interface
期刊論文
Meng, Xin|Li, Meixian|Chen, Zhong|Zhu, Zhiwei|Liang, Zhongwei|Xie, Shubao|Shao, Yuanhua|Li, Bo|
19
Nanoscale Patterning of Multicomponent Proteins by Bias-Assisted Atomic Force Microscopy Nanolithography
期刊論文
Tang, Jilin|Zheng, Zhikun|Xing, Chunyan|Zhang, Bailin|
20
Electrochemistry of symmetrical fullerene dimer C(121) film modified electrodes
期刊論文
Ren, Tongxiang|Shao, Yuanhua|Zhao, Yuliang|Hu, Jingbo|Li, Meixian|Sun, Baoyun|Sun, Nijuan|Zhu, Zhiwei|Miao, Xiaopei|
21
Synthesis of 18-Membered Open-Cage Fullerenes through Controlled Stepwise Fullerene Skeleton Bond Cleavage Processes and Substituent-Mediated Tuning of the Redox Potential of Open- Cage Fullerenes
期刊論文
Zhang, Tong|Liu, Shuming|Xie, Xiang|Li, Yuliang|Gan, Liangbing|Yu, Yuming|Shao, Yuanhua|
22
Study of Heterogeneous Electron Transfer on the Graphene/Self-Assembled Mono layer Modified Gold Electrode by Electrochemical Approaches
期刊論文
Shi, Zujin|Zhao, Keke|Xie, Xiang|Shao, Yuanhua|Xu, Xiaodong|Li, Meixian|Liu, Shujuan|Zhao, Wenbo|Zhu, Zhiwei|
23
A Novel Hydrogen Peroxide Amperometric Sensor based on Thionin Incorporated onto a Mo6S9-xIx Nanowire Modified Glassy Carbon Electrode
期刊論文
Papakonstantinou, Pagona |Mihailovic, Dragan|Cheng, Huiming|Lin, Hong|Miao, Xiaopei|Li, Meixian|
24
Electrochemistry at micro- and nanoscopic liquid/liquid interfaces
期刊論文
Liu, Shujuan|Shao, Yuanhua|Li, Qing|
25
微懸臂樑陣列在電子鼻及生物感測中的套用
期刊論文
張柏林|潘宏青|
26
Ion current rectification and rectification inversion in conical nanopores: a perm-selective view
期刊論文
Shao, Yuanhua |Josserand, Jacques|Momotenko, Dmitry|Girault, Hubert|Liu, Shujuan|Corte´s-Salazar, Fernando|
27
Electrochemical DNAzyme sensor for lead based on amplification of DNA-Au bio-bar codes
期刊論文
Shao, Yuanhua|Le, X. Chris|Li, Qing|Liang, Zhongwei|Chen, Zhong|Xu, Xiaodong|He, Shali|Shen, Li|Zhu, Zhiwei|Xie, Shubao|Li, Yihan|Li, Meixian|Meng, Xin|
28
Interaction Between Tripeptide Gly-Gly-His and Cu2+ Probed by Microcantilevers
期刊論文
Wu, Sanhua|Xu, Yingming|Zhang, Bailin|Pan, Hongqing|
29
Investigation of the interactions between silver nanoparticles and Hela cells by scanning electrochemical microscopy
期刊論文
Liang, Zhongwei|Shao, Yuanhua|Li, Qing|Ma, Hongwei|Me, Shubao|Shen, Li|He, Shali|Huang, Yanyi|Li, Bo|Xu, Xiaodong|Du, Yu|Meng, Xin|Chen, Zhong|
30
Fast Ion-Transfer Processes at Nanoscopic Liquid/Liquid Interfaces
期刊論文
Meng, Xin|Girault, Hubert H.|Xie, Shubao|Shao, Yuanhua|Li, Qing|Liang, Zhongwei|Liu, Shujuan|
31
Molecular recognition force spectroscopy of a specific lectin–carbohydrate interaction at single-molecule level
期刊論文
Wang, Hongda|Qiao, Haiyan|Li, Yongjun|Wang, Laixi|Tang, Jilin|Zhang, Jing|Xing, Chunyan|Zhang, Bailin|
32
The influence of ionic liquids on the fabrication of nonenzymatic glucose electrochemical sensor
期刊論文
Zhu, Hong|Zhu, Zhiwei|Liang, Xianghong|Li, Meixian|Chen, Jitao|
33
PAMAM Dendrimers在水/1,2-二氯乙烷界面上的簡單離子轉移
期刊論文
李博|邵元華|
34
Nonenzymatic glucose voltammetric sensor based on gold nanoparticles/carbon nanotubes/ionic liquid nanocomposite
期刊論文
Lu, Xiaoqing|Zhu, Zhiwei|Shao, Yuanhua|Zhu, Hong|Li, Meixian|
35
鹼基腺嘌呤與胸腺嘧啶在Au(111)電極上的共吸附
期刊論文
徐英明|伍三華|張柏林|
36
Electrochemistry of a C84-C2(IV)-Modified Electrode in Aqueous Solutions and Its Interaction with Guanine
期刊論文
Wang, Shukun|Liu, Lu|Sun, Baoyun|Li, Meixian|Zhu, Zhiwei|
37
Simultaneous and sensitive capillary electrophoretic enantioseparation of three betha-blockers with the combination of achiral ionic liquid and dual CD derivatives
期刊論文
Li, Meixian|Zhu, Zhiwei|Chen, Cheng|Jin, Yue|Meng, Lingchen|Chen, Jitao|
38
收集率與玻璃雙微米管形狀依賴關係的理論模擬與實驗驗證
期刊論文
陳勇|周蜀林|邵元華|梁中偉|高曌|李博|趙文博|胡墨|
39
基於i-DNA的電化學pH感測器研究
期刊論文
邵元華|徐曉東|
40
Probing the structure of a water/nitrobenzene interface by scanning ion conductance microscopy
期刊論文
Zhu, Xinyu|Liu, Shujuan|Liang, Zhongwei|Shao, Yuanhua|Wang, Lingyu|Ji, Tianrong|
41
Highly sensitive detection of melamine and its derivatives by capillary electrophoresis coupled with online preconcentration techniques
期刊論文
Li, Meixian|Zhu, ZHiwei|Jin, Yue|Meng, Lingchen|
42
Molecular Recognition Force Spectroscopy Study of the Specific Lectin and Carbohydrate Interaction in a Living Cell
期刊論文
Li, Yongjun|Xing, Chunyan|Tang, Jilin|Zhang, Bailin|Wang, Hongda|Wang, Jine|Wang, Zhenxin|
43
Atomic Force Microscopy Study on Chlorpromazine-Induced Morphological Changes of Living HeLa Cells In Vitro
期刊論文
Li, Yongjun|Zhang, Jing|Zhang, Bailin|
44
掃描離子電導顯微鏡的原理及套用
期刊論文
紀天容|梁中偉|邵元華|朱新宇|
45
Molecular interactions in self-assembly monolayers on gold-coated microcantilever electrodes
期刊論文
Pan, Hongqing|Xu, Yingming|Wu, Sanhua|Zhang, Bailin|Tang, Jilin|
46
Bioassembled Nanocircuits of Mo6S9-xIx Nanowires for Electrochemical Immunodetection of Estrone Hapten
期刊論文
Gao,Hui |Papakonstantinou,Pagona |Zhang,Xinxiang |Sun, Nijuan|McMullan,Martin |Mihailovic,Dragan |Li,Meixian |
47
Aptamer conjugated Mo6S9−xIx nanowires for direct and highly sensitive electrochemical sensing of thrombin
期刊論文
Li, Meixian|Zhou, Wuzong|Mihailovic, Dragan|Papakonstantinou, Pagona|Sun, Nijuan|McMullan, Martin|
48
Thionin attached to a gold electrode modified with self-assembly of Mo6S9−XIX nanowires for amplified electrochemical detection of natural DNA
期刊論文
Zhu, Zhiwei|Shao, Yuanhua|Liu, Lu|Papakonstantinou, Pagona|Mihailoviˇc, Dragan|Li, Hong|Li, Meixian|Cheng, Huiming|

項目摘要

本研究工作試圖採用各種超微電極、掃描電化學顯微鏡(SECM)、掃描離子電導顯微鏡(SICM)、原子力顯微鏡(AFM)、光學顯微鏡等探討軟界面上分子相互作用和成像分析。軟界面是一個定義較寬的概念,在此我們主要研究液/液界面和液/膜(活細胞)界面。探討這些界面上各種分子之間的相互作用,特別是人工合成抗體-核酸適配體(Aptamers)與各種生物分子的特異性相互作用,發展高選擇性、高靈敏度的分析化學方法和技術。基於這些特異性相互作用,在微米到納米到分子尺度上進行和實現高通量分析-圖像分析。力圖了解不同液/液界面的厚度、活細胞膜上信號的獲取、受體配體對於活細胞的作用機理等。

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