基本介紹
- 中文名：蘇志恆
- 國籍：中國
- 民族：漢族
- 出生地：廣西 南寧
- 出生日期：1981年11月
- 學位/學歷：博士
- 職業：教師
- 專業方向：1.基於代謝組學技術的中藥及複方配伍作用機制研究 2.藥品及食品智慧型分析方法開發 3.大健康產品研發及質量控制
人物經歷,研究方向,在研課題,發表論文,
人物經歷
2000/09–2004/06，瀋陽藥科大學，中藥學院，中藥學，學士
2004/09–2007/06，瀋陽藥科大學，中藥學院，中藥學，碩士
2007/09–2010/06，北京協和醫學院，中國醫學科學院藥用植物研究所，生藥學，博士
擔任廣西醫科大學藥物分析教研室主任、海洋藥物研發中心副主任、藥物分析學科負責人。
曾任致公黨廣西醫科大學副主任委員。
現任致公黨廣西醫科大學主任委員。
研究方向
1.基於代謝組學技術的中藥及複方配伍作用機制研究
2.藥品及食品智慧型分析方法開發
3.大健康產品研發及質量控制
在研課題
1、國家自然科學基金面上項目（基於花生四烯酸代謝調控的“當歸-桂枝”配伍溫經通脈作用機制及藥效物質基礎“靶向組效關係”研究（82174263）），主持，在研。 2、國家自然科學基金青年基金（基於代謝網路“時-空”動態調控的當歸四逆湯“溫經通脈”作用配伍機制及其藥效物質基礎研究（81603533）），主持，已結題。 3、國家自然科學基金地區基金（基於二維"組效關係"的柴胡疏肝散抗抑鬱藥效成分群及配伍規律研究 （81360638）），主持，已結題。 4、廣西自然科學基面上基金（基於微觀組效關係的牛大力抗抑鬱藥效物質基礎及作用機制研究(2018GXNSFAA138096），主持，已結題。 5、廣西自然科學基金青年基金（基於代謝組學的柚皮苷抗抑鬱作用機制研究(2012GXNSFBA053108）），主持，已結題。 6、廣西教育廳高校科研項目（基於定量代謝組學的柚皮苷抗抑鬱作用機制研究（200103YB026）），主持，已結題。 另先後作為主要人員參與國家自然基金、教育部博士點基金、海口市重點科技項目等多項課題研究。 |
發表論文
- Fang Wu, Hua Zheng, Zheng-Teng Yang, Bang Cheng, Jin-Xia Wu, Xu-Wen Liu, Chao-Ling Tang, Shi-Yin Lu, Zhao-Ni Chen, Fang-Ming Song, Jun-Xiang Ruan, Hong-Ye Zhang, Yong-Hong Liang, Hui Song, Zhi-Heng Su▲. Urinary metabonomics study of the hepatoprotective effects of total alkaloids from Corydalis saxicola Bunting on carbontetrachloride-induced chronic hepatotoxicity in rats using 1H NMR analysis. Journal of Pharmaceutical and Biomedical Analysis 140 (2017) 199–209 （通訊作者）
- Yong-Hong Liang, Chao-Ling Tang, Shi-Yin Lu, Bang Cheng, Fang Wu, Zhao-Ni Chen, Fang-ming Song, Jun-Xiang Ruan, Hong-YeZhang, Hui Song, Hua Zheng, Zhi-Heng Su▲. Serum metabonomics study of the hepatoprotective effect of Corydalissaxicola Bunting on carbon tetrachloride-induced acute hepatotoxicity in rats by 1H NMR analysis. Journal of Pharmaceutical and Biomedical Analysis 129 (2016) 70–79. （通訊作者）
- Zhang H, Zheng H, Zhao G, Tang C, Lu S, Cheng B, WuF, Wei J, Liang Y, Ruan J, Song H, Su Z▲.Metabolomic study of corticosterone-induced cytotoxicity in PC12 cells by ultra performance liquid chromatography-quadrupole/time-of-flight mass spectrometry. Mol Biosyst. 2016, 12(3): 902-13. （通訊作者）
- Jin-Bin Wei, Xiong Li, Hui Song, Yong-Hong Liang, Yu-Zheng Pan, Jun-Xiang Ruan, Xia Qin, Yong-Xin Chen, Cai-Li Nong, Zhi-Heng Su▲. Characterization and determination of antioxidant components in the leaves of Camellia chrysantha (Hu) Tuyama based on composition–activity relationship approach. Journal of Food and Drug Analysis. 2015, 23 (1): 40-48 （通訊作者）
- Zhi-heng Su, Hong-mei Jia, Hong-wu Zhang, Yu-fei Feng, Lei An and Zhong-mei Zou. Hippocampus and serum metabolomic studies to explore the regulation of Chaihu-Shu-Gan-San on metabolic network disturbances of rats exposed to chronic variable stress. Molecular BioSystems, 2014, 10 (3), 549-561.
- Zhi-Heng Su, Shu-Qi Li, Guo-An Zou, Chang-Yuan Yu, Yan-Guo Sun, Hong-Wu Zhang, Ying Gu, Zhong-Mei Zou. Urinary metabonomics study of anti-depressive effect of Chaihu-Shu-Gan-San on an experimental model of depression induced by chronic variable stress in rats, Journal of Pharmaceutical and Biomedical Analysis 2011, 55 (3): 533-539.
- Zhi-Heng Su, Guo-An Zou, Hong-Wu Zhang, Zhong-Mei Zou. Online identification of the antioxidant constituents of traditional Chinese medicine formula Chaihu-Shu-Gan-San by LC-LTQ-Orbitrap mass spectrometry and microplate spectrophotometer. Journal of Pharmaceutical and Biomedical Analysis 2010, 53(3): 454-461.
- Hong-mei Jia, Zhi-heng Su, Wei-Long, Yue-tao Liu, Xing Chang, Hong-wu Zhang, Gang Ding, Yu-fei Feng, Da-yong Cai, and Zhong-mei Zou. Metabonomics combined with UPLC-MS chemical profile for discovery of antidepressant ingredients of a traditional Chinese medicines formula, Chaihu-Shu-Gan-San. Evidence-Based Complementary and Alternative Medicine, 2013; 2013: 487158.
- Qi Tang, Zhi-heng Su, Zhen-tai Han, Xiao-jun Ma, De-rong Xu, Yan-hai Liang, Hai-bo Cao, Xue-song Wang, Xiao-ying Qu, Angela Hoffman, Hong-wei Liu, Di-zhou Gu, De-you Qiu. LC–MS method for detecting prostratin in plant extracts and identification of a high-yielding population of Euphorbia fischeriana. Phytochemistry Letters, 2012, 5(1): 214-218.
- Zou GA, Ding G, Su ZH, Yang JS, Zhang HW, Peng CZ, Aisa HA, Zou ZM. Lactonecembranoids from Croton laevigatus. J Nat Prod. 2010 Apr 23; 73(4): 792-5.
- Guo-An Zou, Zhi-Heng Su, Hong-Wu Zhang, Yuan Wang, Jun-Shan Yang, Zhong-Mei Zou. Flavonoids from the Stems of Croton caudatus Geisel. var. tomentosus Hook. Molecules 2010, 15(3): 1097-1102.
- S. Q. Li, Z. H. Su, J. B. Peng, Z. M. Zou, C. Y. Yu, In Vitro and in Vivo Antioxidant Effects and the Possible Relationship between the Antidepression Efficacy of Traditional Chinese Medicine Formulation Chai-hu-Shu-gan-San, Chin. J. Nat. Med., 8(2010) 353-361.
