《藍藻細胞分化信號轉導和分子調控機理研究》是趙進東為項目負責人，北京大學為依託單位的重點項目。
基本介紹
- 中文名：藍藻細胞分化信號轉導和分子調控機理研究
- 項目類別 ：重點項目
- 項目負責人：趙進東
- 依託單位 ：北京大學
科研成果,項目摘要,
科研成果
序號 | 標題 | 類型 | 作者 |
|---|---|---|---|
1 | Construction of a non-antibiotic expression system in a marine cyanobacterium Synechococcus sp PCC 7002 and its application in production of oral vaccine against enterotoxin of Escherichia coli | 期刊論文 | Yu, Xin|Guo, Cong|Zhao, Jindong|Xu, Dongyi| |
2 | MreB is important for cell shape but not for chromosome segregation of the filamentous cyanobacterium Anabaena sp PCC 7120 | 期刊論文 | Zhao, Weixing|Zhang, Yingjiao|Zhao, Jindong|Hu, Bin|Yang, Guohua| |
3 | A membrane-associated Mn-superoxide dismutase protects the photosynthetic apparatus and nitrogenase from oxidative damage in the cyanobacterium Anabaena sp PCC 7120 | 期刊論文 | Zhao, Weixing|Zhao, Jindong|Guo, Qinxi| |
4 | ApcD is necessary for efficient energy transfer from phycobilisomes to photosystem I and helps to prevent photoinhibition in the cyanobacterium Synechococcus sp PCC 7002 | 期刊論文 | Dong, Chunxia|Tang, Aihui|Shen, Gaozhong|Zhao, Jindong|Mullineaux, Conrad W.|Bryant, Donald A.| |
5 | Methylglyoxal detoxification by an aldo-keto reductase in the cyanobacterium Synechococcus sp PCC 7002 | 期刊論文 | Xu, Dongyi|Liu, Xianwei|Zhao, Jindong|Guo, Cong| |
6 | PII, the key regulator of nitrogen metabolism in the cyanobacteria | 期刊論文 | Zhang Ying|Zhao JinDong| |
7 | ApcD is required for state transition but not involved in blue-light induced quenching in the cyanobacterium Anabaena sp PCC7120 | 期刊論文 | Dong ChunXia|Zhao JinDong| |
8 | PII is important in regulation of nitrogen metabolism but not required for heterocyst formation in the cyanobacterium Anabaena sp PCC 7120 | 期刊論文 | Zhang, Yan|Zhao, Jindong|Zhang, Ying|Zhao, Weixing|Wang, Qingsong|Cheng, Shu|Pu, Hai| |
9 | Regulation of intracellular free calcium concentration during heterocyst differentiation by HetR and NtcA in Anabaena sp PCC 7120 | 期刊論文 | Shi, Yunming|Zhao, Weixing|Zhao, Jindong|Zhang, Wei|Ye, Zi| |
10 | RbrA, a cyanobacterial rubrerythrin, functions as a FNR-dependent peroxidase in heterocysts in protection of nitrogenase from damage by hydrogen peroxide in Anabaena sp PCC 7120 | 期刊論文 | Zhao, Jindong|Ye, Zi|Zhao, Weixing| |
項目摘要
一些藍藻在缺氮條件下或與植物共生時，部分營養細胞分化為異型胞，作為固氮的場所。本項目擬利用分子生物學，細胞生物學，生物化學和蛋白組學等方法，研究異型胞分化中的信號感受和信號轉導途徑，探索HetR等關鍵蛋白和轉錄因子NtcA調控異型胞分化的機理，尋找HetR底物；著重研究α-酮戊二酸和鈣信號的轉導機理和相互關係，探討P-II蛋白在信號轉導中的作用。利用突變體研究植物信號調控共生藍藻的光合作用以及異型
