2013年獲南開大學博士學位（師從程津培院士）。2010年8-10月在北京大學余志祥課題組交流學習。2011年6-8月及2012年5-10月在美國Utah State University物理有機化學家Vernon D Parker教授課題組交流訪問。2017年9-2019年9月，在美國University of California, Los Angeles 美國科學院院士Ken N Houk教授課題組訪問學者。研究領域為物理有機化學（理論有機方向），包括：1）物理有機氟化學；2）化學鍵能學；3）反應機理研究；4）計算化學。已發表SCI收錄學術論文40餘篇，其中包括Chem. Rev., J. Am. Chem. Soc.，Angew, Chem., J. Org. Chem.，Org. Lett.等有機化學領域著名期刊。Chemical Science, Org. Lett.，J. Org. Chem.，Org. Biomol.Chem.,Tetrahedron Lett.，J. Fluorine.Chem.等期刊審稿人。
基本介紹
- 中文名：薛小松
- 國籍：中國
- 民族：漢
- 職業：大學教師
- 畢業院校：南開大學
近期部分發表文章：
[1] Biying Zhou; Moriana K. Haj; Eric N. Jacobsen; Houk, K. N.,* Xue, Xiao-Song;* Mechanism and Origins of Chemo- and Stereoselectivities of Aryl Iodide-Catalyzed Asymmetric Difluorinations of β-Substituted Styrenes, J. Am. Chem. Soc. 2018. 140, 15206.
[2] Jingjing Zhang; Yang Jin-Dong; Hanliang Zheng;Xue, Xiao-Song;*Herbert Mayr;* Cheng Jin-Pei. Exploration of the Synthetic Potential of Electrophilic Trifluoromethylthiolating and Difluoromethylthiolating Reagents,Angew. Chem. Int. Ed.2018, 57, 12690.
[3] Yang Jin-Dong, Ji Pengju, Xue Xiao-Song, Jin-Pei Cheng* Recent Advances and Advisable Applications of Bond Energetics in Organic Chemistry, J. Am. Chem. Soc. 2018. 140, 8611.
[4] Di Wang, Xiao-Song Xue, Kendall N. Houk,* and Zhuangzhi Shi.* Mild Ring-Opening 1,3-Hydroborations of Non-Activated Cyclopropanes, Angew. Chem. Int. Ed. 2018, DOI: 10.1002/anie.201811036.
[5] Xue Xiao-Song; Levandowski, Brian J.; Cyndi Qixin He; Houk, K. N.,* Origins of Selectivities in the Stork Diels–Alder Cycloaddition for the Synthesis of (±)-4-Methylenegermine, Org. Lett., 2018. 20, 6108.
[6] Wang, Zhen; Wang, Fang; Xue Xiao-Song;* Ji, Pengju,* Acidity Scale of N-Heterocyclic Carbene Precursors: Can We Predict the Stability of NHC–CO2 Adducts? Org. Lett., 2018. 20, 6041.
[7] Zhu Jiansheng; Zheng Hanliang; Xue, Xiao-Song*; Xiao Yisa; Liu Yafei; Shen Qilong;* Carbon-Selective Difluoromethylation of Soft Carbon Nucleophiles with Difluoromethylated Sulfonium Ylide, Chin. J. Chem.2018. 36, 1069.
[8] Man, Li; Huiying, Kang; Xiao-Song, Xue*; Jin-Pei, Cheng; Computational Study of the Trifluoromethyl Radical Donor Abilities of CF3 Sources, Acta Chim. Sinica2018. (Invited contribution)
[9] Li, Man; Yueqian Sang; Xue, Xiao-Song;* Cheng, Jin-Pei. Origin of Stereocontrol in Photoredox Organocatalysis of Asymmetric α-Functionalizations of Aldehydes. J. Org. Chem. 2018. 83, 3333.
[10] Zhengwei Guo; Man Li; Xue-Qing Mou; Gang He;* Xiao-Song Xue*; Gong Chen* Radical C–H Arylation of Oxazoles with Aryl Iodides: dppf as an Electron-Transfer Mediator for Cs2CO3. Org. Lett., 2018, 20, 1684.
[11] Wang Zhen; Zheng Yongjun; Zheng Yong; Xue, Xiao-Song;* Ji Pengju * A Systematic Theoretical Study on the Acidities for Cations of Ionic Liquids in Dimethyl Sulfoxide J. Phys. Chem. A 2018, 122, 5750.
[12] Li, Man; Zhen, Hanliang; Xue, Xiao-Song;* Cheng, Jin-Pei. Ordering the relative power of electrophilic fluorinating, trifluoromethylating, and trifluoromethylthiolating reagents: A summary of recent efforts. Tetrahedron Lett. 2018, 59, 1278. (Invited review)
[13] Li, Man; Xue, Xiao-Song;* Cheng, Jin-Pei. Mechanism and Origins of Stereoinduction in Natural Cinchona Alkaloid Catalyzed Asymmetric Electrophilic Trifluoromethylthiolation of β-Ketoesters with N-Trifluoromethylthiophthalimide as Electrophilic SCF3 Source. ACS Catal., 2017, 7, 7977.
[14] Li, Man; Zhou, Biying; Xue, Xiao-Song;* Cheng, Jin-Pei. Establishing the Trifluoromethylthio Radical Donating Abilities of Electrophilic SCF3-Transfer Reagents. J. Org. Chem. 2017. 82, 8697.
[15] Xue, Xiao-Song;# Ji, Pengju,# Zhou, Biying; Cheng, Jin-Pei*. The Essential Role of Bond Energetics in C–H Activation/Functionalization.Chem. Rev. 2017, 117, 8622. (# equally contribution)
[16] Jiang, Shan; Yan, Tai-Shan; Han, Yong-Chao; Cui, Li-Qian; Xue, Xiao-Song;* Zhang, Chi* Hypervalent-Iodine-Mediated Formation of Epoxides from Carbon(sp)–Carbon(sp) Single Bonds. J. Org. Chem. 2017, 82, 11691.
[17] Li, Yao; He, Qixin Cyndi; Gao, Fei-Xiang; Li, Zhen; Xue, Xiao-Song; Li, Xin;* Houk, K. N.;* Cheng, Jin-Pei. Design and Applications of N-tert-Butyl Sulfinyl Squaramide Catalysts. Org. Lett. 2017, 19, 1926.
[18] Yang, Jin-Dong; Wang, Ya; Xue, Xiao-Song;* Cheng, Jin-Pei*. A Systematic Evaluation of the N-F Bond Strength of Electrophilic N-F Reagents: Hints for Atomic Fluorine Donating Ability. J. Org. Chem. 2017, 82, 4129.
[19] Li, Man.; Wang, Ya; Xue, Xiao-Song;* Cheng, Jin-Pei. A Systematic Assessment of Trifluoromethyl Radical Donor Abilities of Electrophilic Trifluoromethylating Reagents. AsianJ. Org. Chem. 2017. 6, 235.
[20] Zhou, Biying; Xue, Xiao-Song;* Cheng, Jin-Pei. Theoretical study of Lewis acid activation models for hypervalent fluoroiodane reagent: The generality of “F-coordination” activation model. Tetrahedron Lett. 2017, 58,1287.
[21] Zhou, Biying; Yan, Taishan.; Xue, Xiao-Song;* Cheng, Jin-Pei. Mechanism of Silver-Mediated Geminal Difluorination of Styrenes with a Fluoroiodane Reagent: Insights into Lewis-Acid-Activation Model. Org. Lett. 2016, 18, 6128.
[22] Yan, Taishan.; Zhou, Biying; Xue, Xiao-Song;* Cheng, Jin-Pei*. Mechanism and Origin of Unexpected Chemoselectivity in Fluorocyclization of o-Styryl benzamides with a Hypervalent Fluoroiodane Reagent. J. Org. Chem. 2016, 81, 9006.
[23] Li, Man.; Guo, Jinping; Xue, Xiao-Song; * Cheng, Jin-Pei*. Quantitative Scale for the rifluoromethylthio Cation-Donating Ability of Electrophilic Trifluoromethylthiolating Reagents. Org. Lett. 2016, 18, 264.
[24] Li, Man.; Xue, Xiao-Song;* Guo, Jinping; Wang, Ya; Cheng, Jin-Pei*.An Energetic Guide for Estimating Trifluoromethyl Cation Donor Abilities of Electrophilic Trifluoromethylating Reagents: Computations of X–CF3 Bond Heterolytic Dissociation Enthalpies. J. Org. Chem. 2016, 81, 3119.
[25] Xue, Xiao-Song; * Wang, Ya; Man, Li; Cheng, Jin-Pei*. Comprehensive Energetic Scale for Quantitatively Estimating the Fluorinating Potential of N–F Reagents in Electrophilic Fluorinations. J. Org. Chem.2016, 81, 4280.
[26] Zhang, Panpan; Li , Man; Xue, Xiao-Song; * Xu, Chunfa; Zhao, Qunchao; Liu, Yafei; Wang, HaoYang; Guo, Yinlong; Lu, Long;* Shen, Qilong.* N-Trifluoromethylthiodibenzenesulfonimide: A Shelf-Stable, Broadly Applicable Electrophilic Trifluoromethylthiolating Reagent. J. Org. Chem.2016, 81, 7486.
[27] Dong, Nan; Zhang, Zhi. Pei; Xue, Xiao-Song; Li, Xin*; Cheng, Jin-Pei. Phosphoric Acid Catalyzed Asymmetric 1,6-Conjugate Addition of Thioacetic Acid to para-Quinone Methides. Angew. Chem. Int. Ed. 2016, 55, 1460.
[28] Xue, Xiao-Song; * Wang, Ya; Chen, Yang; Ji, Pengju, Cheng, Jin-Pei*. Toward Prediction of the Chemistry in Ionic Liquids: An Accurate Computation of Absolute pKa Values of Benzoic Acids and Benzenethiols. J. Org. Chem. 2015, 80, 8997.
[29] Wang, Feng; Yang, Chen.; Xue, Xiao-Song; Li, Xin.; Cheng, Jin-Pei. A Highly Efficient Chirality Switchable Synthesis of Dihydropyran-Fused Benzofurans by Fine-Tuning the Phenolic Proton of β-Isocupreidine (β-ICD) Catalyst with Methyl.Chem. Eur. J. 2015, 21, 10443.
[30] Xue, Xiao-Song; Chen, Yang; Li, Xin;* Cheng, Jin-Pei*. A Computational Study on the pKa Shifts of Proline Induced by Hydrogen-bond Donating Co-catalysts J. Org. Chem.2014, 79, 1166.
[31] Chen, Yang; Xue, Xiao-Song; Li, Xin;* Cheng, Jin-Pei*. Computational Study on the Acidic Constants of Chiral Brønsted Acids in Dimethyl Sulfoxide J. Org. Chem. 2014, 79, 4340.
[32] Xue, Xiao-Song; Chen, Yang; Li, Xin; Cheng, Jin-Pei*. Computation of Standard Equilibrium Acidity of C-H Acids in Ionic Media: Shedding Light on Predicting Changes of Chemical Behavior by Switching Solvent System from Molecular to Ionic. Org. Chem. Front. 2014, 1, 176.
[33] Xue, Xiao-Song; Li, Xin; Yu, Ao;* Chen, Yang; Song, Chan; Cheng, Jin-Pei*. Mechanism and Selectivity of Bio-inspired Novel Cinchona Alkaloid Derivatives Catalyzed Asymmetric Olefin Isomerization: A Computational Study. J. Am. Chem. Soc. 2013, 135, 7462.
[34] Yang, Chen; Xue, Xiao-Song; Jin, Jialu; Li, Xin*; Cheng, Jin-Pei*. Theoretical Study on the Acidities of Chiral Phosphoric Acids in Dimethyl Sulfoxide: Hints for Organocatalysis. J. Org. Chem. 2013, 78, 7076.
[35] Li, Xin*; Yang, Chen; Jin, Jialu; Xue, Xiao-Song; Cheng, Jin-Pei*. Synthesis of Optically Enriched Spirocyclic Benzofuran-2-ones via Bifunctional Thiourea Catalyzed Double-Michael Addition of Benzofuran-2-ones to Dienones. Chem. Asian J. 2013, 8, 4.
[36] Li, X;* Liu. Cong; Xue, Xiao-Song; Cheng, Jin-Pei*. Enantioselective Organocatalyzed Sulfenylation of 3-Substituted Oxindoles. Org. Lett. 2012, 4374.
[37] Li, Xin;* Xue, Xiao-Song; Liu, Cong; Wang, Bin; Tan, Boxuan; Jin, Jialu; Zhang, Yueyan; Dong, Nan; Cheng, Jin-Pei*. Asymmetric Michael Addition Reactions of 3-Substituted Benzofuran-2(3H)-ones to Nitroolefins Catalyzed by a Bifunctional Tertiary-amine thiourea. Org. Biomol. Chem. 2012, 10, 413.
[38] Yu, Ao*; Xue, Xiao-Song; Wang, Jian.; Wang, Huikai.; Wang, Yongjian, The Effects of Insertion of Nitrogen Atoms on the Aromatic Nitrogen-Containing Compounds: a Potential Approach for Designing Stable Radical Molecular Materials. J. Phys. Org. Chem. 2012, 25, 92.
[39] Li, Xin*; Zhang, Yuanyan; Xue, Xiao-Song; Jin, Jialu; Tan, Boxuan; Liu, Cong; Dong, Nan; Cheng, Jin-Pei*. Asymmetric Michael Addition Reactions between 3-Substituted Benzofuran-2(3H)-ones and 1,1-Bis(phenylsulfonyl)ethylene Catalyzed by Bifunctional Catalysts Containing Tertiary Amine and Thiourea Groups. Eur. J. Org. Chem. 2012, 1774.
[40] Xue, Xiao-Song; Yu, Ao;* Cai, Yu; Cheng, Jin-Pei. A Computational Reinvestigation of the Formation of N-Alkylpyrroles via Intermolecular Redox Amination. Org. Lett. 2011, 13, 6054.
[41] Hou, Yanhui;* Wang, Huikai; Li, Zhi; Liu, Yongshen; Wan, Xianjian; Xue, Xiao-Song; Chen, Yongsheng; Yu, Ao. Organic Radicals Based on Phenalenyl and Verdazyl Units. Tetrahedron Lett. 2011, 52, 3670.
[42] Yu, Ao;* Wang, Jijian; Xue, Xiao-Song; Wang, Yongjian*. Theoretical Study of the Peripheral Disulfide Bridge Substituent Effects on the Antioxidant Properties of Naphthyridine Diol Derivatives. J. Phys. Chem. A. 2010, 114, 1008.
Zhang, Huaqiang; Wan, Xianjian; Xue, Xiao-Song; Li, Yanqin; Yu, Ao; Chen, Yongsheng*. Selective Tuning of the HOMO-LUMO Gap of Carbazole-Based Donor-Acceptor-Donor Compounds toward Different Emission Colors. Eur. J. Org. Chem. 2010, 1681.
