人物經歷
教育經歷
2003年 中國科學院上海生理研究所 理學博士
1999年 華東師範大學 理學碩士
1996年 華東師範大學 理學學士
工作經歷
2013年7月 北京大學 研究員
2009-2013年 約翰霍普金斯大學醫學院神經科學系 助理研究員(Research Associate, Faculty)
2003-2009年 約翰霍普金斯大學醫學院神經科學系 博士後
研究方向
神經生物學
主要成就
2023年10月,北大生命科學學院、麥戈文腦研究所、定量生物學中心、生命科學聯合中心羅冬根研究員團隊發現“一細胞,兩遞質,兩視覺功能”的神經機制。
代表性論文
1. Xiao N, Xu S, Li ZK, Tang M, Mao R, Yang T, Ma SX, Wang PH, Li MT, Sunikumar A, Rouyer F, Cao LH, and Luo DG. (2023) A single photoreceptor splits perception and entrainment by cotransmission. Nature (in press).
2. Tang M, Cao LH, Yang T, Ma SX, Jing BY, Xiao N, Xu S, Leng KR, Yang D, Li MT, Luo DG.(2022) An extra-clock ultradian brain oscillator sustains circadian timekeeping. Science Advances 8, eabo5506.
3. Luo DG, Silverman D, Frederiksen R, Adhikari R, Cao LH, Oatis JE, Kono M, Cornwall MC, and Yau KW. (2020) Apo-opsin and its dark constitutive activity across retinal cone subtypes. Current Biology 30: 4921-4931.
4. Wu F, Deng B, Xiao N, Wang T, Li Y, Wang R, Shi K, Luo DG, Rao Y, Zhou C. (2020) A neuropeptide regulates fighting behavior in Drosophila melanogaster. Elife e54229.
5. Zhou Y, Cao LH, Sui XW, Guo XQ, and Luo DG. Mechanosensory circuits coordinate two opposing motor actions in Drosophila feeding. Science Advances 2019, 5: eaaw5141.
6. Li MT, Cao LH, Xiao N, Tang M, Deng B, Yang T, Yoshii T, and Luo DG. Hub-organized parallel circuits of central circadian pacemaker neurons for visual photoentrainment in Drosophila. Nature Communications 2018, 9: 4247.
7. Cao LH, Yang D, Wu W, Zeng X, Jing BY, Li MT, Qin SS, Tang C, Tu Y, and Luo DG. Odor-evoked inhibition of olfactory sensory neurons drives olfactory perception in Drosophila. Nature Communications 2017, 8: 1357.
8. Yue WW, Frederiksen R, Ren X, Luo DG, Yamashita T, Shichida Y, Cornwall MC, Yau KW. Spontaneous activation of visual pigments in relation to openness/closedness of chromophore-binding pocket. eLife, 2017, 6. pii: e18492.
9. Cao LH, Jing BY, Yang D, Zeng X, Shen Y, Tu Y and Luo DG. Distinct signaling of Drosophila chemoreceptors in olfactory sensory neurons. Proc. Natl. Acad. Sci. USA, 2016, 113, E902-E911.
10. Cao LH, Luo DG and Yau KW. Light responses of primate and other mammalian cones. Proc. Natl. Acad. Sci. USA, 2014, 111, 2752-2757.
11. Luo DG*, Yue WWs, Ala-Laurila P and Yau KW*. Activation of visual pigments by light and heat. Science, 2011, 332, 1037-1032. (*Co-corresponding Authors)
12. Fu Y*, Kefalov VJ*, Luo DG*, Xue T* and Yau KW. Quantal noise from human red cone pigment. Nature Neuroscience, 2008, 11, 565-571. (*Equal Contributions)
13. Luo DG, Xue T, and Yau KW. How vision begins: an odyssey. Proc. Natl. Acad. Sci. USA, 2008, 105, 9855-9862.
14. Su CY, Luo DG, Terakita A, Schichida Y, Liao HW, Kazmi MA, Sakamar TP and Yau KW. Parietal-eye phototransduction components and their potential evolutionary implications. Science, 2006, 311, 11617-11621.
15. Luo DG and Yau KW. Rod sensitivity of neonatal mouse and rat. J. Gen. Physiol., 2005, 126, 263-269.
16. Fu YB, Zhong HN, Wang MH, Luo DG, Liao HW, Maeda H, Hattar S, Frishman LJ and Yau KW. Intrinsically photosensitive retinal ganglion cells detect light with a Vitamin A-based photopigment, melanopsin. Proc. Natl. Acad. Sci. USA, 2005, 102, 10339-10344.
17. Huttl S, Michalakis S, Seeliger M, Luo DG, Acar N, Geiger H, Hudl K, Mader R, Haverkamp S, MOser M, Pfeifer A, Gerstner A, Yau KW and Beil M. Impaired channel targeting and retinal degeneration i mice lacking the cyclic nucleotide-gated channel subunit CNGB1. J. Neurosci., 2005, 25, 130-138.
18. Luo DG, Li GL and Yang XL. Zn2+ modulates light responses of color-opponent bipolar and amacrine cells in the carp retina. Brain Res. Bull., 2002, 58, 461-468.
19. Luo DG and Yang XL. Suppression by zinc of transient OFF responses of carp amacrine cells to red light is mediated by GABAa receptors. Brain Res., 2002, 958, 222-226.
20. Luo DG and Yang XL. Zn2+ differentially modulates signals from red- and short-wavelenth-sensitive cones to horizontal cells in carp reitna. Brain Res., 2001, 900, 95-102.
21. Xu HP, Luo DG and Yang XL. Signals from cone photoreceptors to L-tyoe horizontal cells are differntially modulated by low calcium in carp retina. Eur. J. Neurosci., 2001, 13, 1411-1419.