盧榮華，博士（後），碩士生導師，教授。西北農林科技大學理學博士，華中農業大學水產養殖博士後。
主要承擔本科生、碩士和博士研究生的《魚類營養學》、《水產動物飼料學》以及《水產動物營養與飼料學研究進展》等理論及實驗課程的教學工作。近年來曾在《Aquaculture》《General and Comparative Endocrinology》《Fish Physiology and Biochemistry》《Molecular Biology Reports》《Reproduction in Domestic Animals》《Cryobiology》《Fish and shellfish immunology》、《水產學報》《生物化學與分子生物學報》、《中國水產科學》和《生物工程學報》等期刊發表研究論文四十餘篇。
基本介紹
人物經歷,教育背景,工作經歷,學術兼職,承擔課程,研究方向,參與課題,代表論文,獲獎榮譽,
人物經歷
Jul.2012—present, College of Fisheries, Henan Normal University Association Professor
Feb.2010—Jul, 2012, College of Fisheries, Huazhong Agricultural University,Postdoctoral Research Fellow
Jul.2000-Sep.2003, HeNan Guosen Feed Company., Ltd, Zhengzhou County, HenanProvince
教育背景
- 博士(2006/09-2009/12): 西北農林科技大學，動物科技學院，動物學專業
- 碩士(2003/09-2006/07): 西北農林科技大學，動物科技學院，動物遺傳育種與繁殖專業
- 學士(1996/09-2000/07): 河南農業大學，牧醫工程學院，畜牧專業
工作經歷
- 2022/03- ：河南師範大學水產學院，教授
- 2016/04- 2022/02：河南師範大學水產學院，副教授
- 2012/07-2016/03：河南師範大學水產學院，講師（副教授待遇）
- 2010/02-2012/06：華中農業大學，博士後
學術兼職
- 河南省科技特派員
- 河南省水產學會會員
承擔課程
1.《魚類營養學》、《水產動物飼料學》(本科)
2.《水產動物營養與飼料學研究進展》(博士研究生)
研究方向
主要研究領域是水產動物營養與飼料科學。主要研究方向：
1、淡水魚類脂質代謝的調控：通過營養學手段調控淡水養殖魚類脂質代謝，改善養殖魚類品質，提高魚類免疫力；
2、實用飼料原料開發：脂肪及蛋白源飼料原料資源評價、環保型飼料開發。
參與課題
1. 草魚脂肪肝細胞exosomes傳遞miR-122調節肝細胞與免疫細胞間相互作用和機制研究（U1704109），NSFC-河南省聯合基金，主持人。
2. Irisin通過AMPK和PI3K/Akt信號通路調控鯉糖代謝的機制研究（31872581），國家自然科學基金委員會，61萬，第一參與人。
3. 肝細胞源exosome介導miR-122調節草魚脂肪肝代謝的作用及機制研究（182102410031），河南省重點科技攻關項目（國家科技合作領域）10萬，主持人。
4. 基於綜合改革提高水產養殖專業大學生核心競爭力的研究與實踐（2017SJGLX277），河南省高等教育教學改革研究與實踐項目，主持人。
5.2018、2019河南省三區科技人才項目，2018-2020年，4萬元，主持人。
6. 蚯蚓粉及蚯蚓糞在鯉魚飼料中的套用研究，2019年新鄉市科技攻關計畫項目，主持人。
7. microRNA-122/33調控SREBP-1c介導的草魚脂代謝的作用及機理研究（31402311），國家自然科學基金委員會，主持人。
8. 固醇調節原件結合蛋白（SREBPs）抑制子kun82的篩選及其調控脂代謝的作用機理研究（31401014）,國家自然科學基金委員會, 第一參與人。
9. PGC-1β調節草魚脂肪肝細胞糖脂代謝機理研究（13A240548），教育廳科學技術研究重點項目-基礎項目，主持人。
10.幾種主要淡水魚類腸道放線菌資源的多樣性研究及生物活性分析（01346500101），博士啟動課題，主持人。
11.調控草魚肝脂肪代謝的miRNAs篩選及相關miRNAs功能初步分析（2013PL09），河南師範大學青年基金，主持人。
12.HUFA誘導草魚脂肪細胞凋亡的作用及其機制分析（31372538），國家自然科學基金委會，第一參與人。
13. PUFA對草魚脂肪細胞線粒體發育的影響及其機制分析（31072223），國家自然科學基金委員會，第二參與人。
14.瘦素(leptin)對黃顙魚卵巢發育的影響及機理(31001101)，國家自然科學基金委員會，第二參與人。
15.鱖魚馴食相關基因功能分析與機理研究（31272641）國家自然科學基金委員會，第三參與人。
16. leptin對草魚和鱖魚糖脂代謝及攝食調控機理比較研究（31172420），國家自然科學基金委員會，第五參與人。
17.多不飽和脂肪酸對草魚脂肪細胞發育的影響及其分子機理的研究（30771667），國家自然科學基金委員會，第三參與人。
18.ATG5及AMPK-FOXO3介導的脂噬在miR-33調節草魚營養性脂肪肝中的機制分析（222300420469），河南省科技廳，自然科學基金面上項目，2022-01至2023-12，在研，主持。
代表論文
[1] Ronghua Lu, Chaobin Qin, Yang Feng, et al. Grape seed proanthocyanidin extract ameliorates hepatic lipid accumulationand inflammation in grass carp (Ctenopharyngodon idella), Fish PhysiolBiochem, (2020).46 (5): 1665-1677.
[2] Rong-Hua Lu, Meng-Jun Lin, Feng Yang, Shen-zong Jia,Yu-Ru Zhang, Chao-Bin Qin, Xiao-Lin Meng, Guo-Xing Nie. Anti-miR33 therapy improved hepatopancreaticlipid and immune metabolism disorders in grass carp, Ctenopharyngodon Idella. Fish Physiol Biochem, (2021).
[3] Lu R-H, Jia S-Z, Yang F, et al. The function of miR-122 in thelipid metabolism and immunity of grass carp (Ctenopharyngodon idellus). Aquaculture Reports, (2020), 17:100401.
[4] Ronghua Lu, Yanna Chen, Weipeng Yu, Mengjun Lin, Guokun Yang, Chaobin Qin, Xiaolin Meng, Yanmin Zhang, Hong Ji, Guoxing Nie. Defatted blacksoldier fly (Hermetia illucens) larvae meal can replace soybean mealin juvenile grass carp (Ctenopharyngodon idellus) diets, Aquaculture Reports, (2020).18:100520.
[5] Shang-hong Ji, Jian Sun, Chenchen Bian, Xiaocheng Huang,Zhiguang Chang, Rong-Hua Lu*, Hong Ji*.cAMP-dependentprotein kinase A in grass carp Ctenopharyngodon idella: Molecularcharacterization, gene structure, tissue distribution and mRNA expression inendoplasmic reticulum stress-induced adipocyte lipolysis, ComparativeBiochemistry and Physiology Part B: Biochemistry and Molecular Biology, (2020),250: 110479
[6] Jian Sun, Handong Li, Xiaolong Luo, Ronghua Lu*& Hong Ji*. Identification and characterization of two isoforms ofacyl-coenzyme A oxidase 1 gene and their expression in fasting-induced grasscarp Ctenopharyngodon idella adipocyte lipolysis. FishPhysiology and Biochemistry, (2020), 46:1645–1652.
[7] LU Ronghua, ZHANG Wenya, ZHANG Yuru, YANG Liping,WANG Junli , MENGXiaolin , NIE Guoxing*. Isolation and identification of hepatocellular exosomesand there effects on the expression of miR-122/33 and immune-related genes ingrass carp (Ctenopharyngodon idella). Journal of fisheries of china. (2020),44(01):1-10
[8] Yanna Chen, Ronghua Lu, Guokun Yang, YuruZhang, Chaobin Qin, Hong Ji, Guoxing Nie. Effect of replacingsoybean oil with black soldier fly (Hermetia illucens) larvae oil on thegrowth performance, anti-oxidant enzyme activity and intestinal microbiota ofgrass carp (Ctenopharyngodon idellus). Journal of fisheries of china.(2019),43(10):2241-2255. (In Chinese)
[9] Lu Ronghua,Ji hong, Nie Guoxing*. Function of adipose-derived exosomes and researchprogess in aquatic animals. Journal of fisheries of china. (2019),43(10):2049-2059.(In Chinese)
[10]Lu Ronghua, Zhang Wenya, Liang Xufang*, Li Xiyang, Dou Yaqi, Yu Rui. Comparisonof body lipid deposition of blunt snout beream (Megalobrama amblycephala YIH)between Liangzi Lake and Yuni Lake. Journal of Huazhong Agricultural University.(2019), 38(02):17-22. (In Chinese)
[11] Lu Ronghua, Wang Junli, Sun junjun, Yang feng, Xie dizhi, Tian Xue, NieGuoxing, Current research progress in fish miRNAs. Fisheries Science. (2017), 36 (2):231-236. (In Chinese)
[12] Wang J, Lu R, Sun J, et al.Differential expression of lipid metabolism-related genes and miRNAs in Ctenopharyngodonidella liver in relation to fatty liver induced by high non-protein energydiets. Aquaculture Research, (2016), 48(8).
[13] Rong-hua Lu, Zhi-guang Chang, Jian Sun,Feng Yang, Guo-xing Nie, Hong Ji. Molecular cloning, expression and functionalcharacterization of tumor necrosis factor (TNF) receptor-associated factor(TRAF)-interacting protein (TRIP) in grass carp, Ctenopharyngodon idella. Fish & Shellfish Immunology. (2016),57:406-412.
[14] FengYang, Chao-bin Qin, Rong-hua Lu, Jun-junSun, Li-ping Yang, Guo-xing Nie. Molecular cloning, tissue distribution andnutritional regulation of AdipoR1-B in grass carp (Ctenopharyngodon idella). Journal of fisheries of china. (2016),40(7):993-1005.(In Chinese)
[15] Xiao Yan,Li-ping Yang, Wen-jia Zheng, Jun-jun Sun, Rong-huaLu, Guo-xing Nie. Preparation of the antibody and tissue distribution ofthe peptide transporter PepT1 in Cyprinus carpioL.. Journal of Fishery Sciences of China. (2016),23(3):513-521. (In Chinese)
[16] Rong-hua Lu*, Yi Zhou*, Xiao-chen Yuan,Xu-Fang Liang, Liu Fang, Xiao-li Bai, Min Wang, Yu-hua Zhao. Effects ofglucose, insulin and triiodothyroxine on leptin and leptin receptor expressionand the effects of leptin on activities of enzymes related to glucosemetabolism in grass carp (Ctenopharyngodonidella) hepatocytes. Fish Physiol Biochem. (2015),41(4):981-989.
[17] Jing-JingTian, Rong-Hua Lu, Hong Ji, JianSun, Chao Li, Pin Liu, Cai-Xia Lei, Li-Qiao Chen, Zhen-Yu Du. Comparativeanalysis of the hepatopancreas transcriptome of grass carp (Ctenopharyngodon idellus) fed with lardoil and fish oil diets. Gene. (2015),565(2):192-200
[18] Jun-LiWang, Xiao-lin Meng, Rong-hua Lu,Chun Wu, Yan-Ting Luo, Xiao Yan, Xue-Jun Li, Xiang-Hui Kong, Guo-Xing Nie.Effects of Rehmannia glutinosa on growth performance,immunological parametersand disease resistance to Aeromonas hydrophila in common carp (Cyprinus carpio L.). Aquaculture. (2015),435:293-300
[19] Rong-hua Lu, Xu-fang Liang, Junjun Sun,Feng Yang, Min Wang, Xiyang Li, Xiaoli Bai. Establishment of a model of grasscarp hepatocyte steatosis and analysis of lipid metabolism gene expression.Journal of Fishery Sciences of China. 2015, 22(1): 24-32. (In Chinese)
[20] Rong-hua Lu, Feng Yang, Jun-jun Sun, Di-zhiXie, Chao-bin Qin, Li-ping Yang, Wen-jia Zheng, Guo-xing Nie. Molecular cloningof PGC-1β gene and effects of high carbohydrate and high fat feed on itsexpression in liver of grass carp Ctenopharyngodonidella. Journal of fisheries of china.(2015),39(9):1283-1290. (In Chinese)
[21] Rong-Hua Lu, Jun-Jun Sun, Xu-FangLiang, Guo-Xing Nie and Feng Yang. Biological characteristics and functions ofleptin in fish. Acta Hydrobiologica Sinica. (2015) 39(3):583-589. (In Chinese)
[22] Jun-junSun, Rong-hua Lu, Feng Yang,Chao-bin Qin, Li-ping Yang, Jun-li Wang, Xiang-hui Kong, Xue-jun Li, Guo-xingNie. Molecular cloning of SREBP-1 gene and effects of carbohydrates on itsexpression in liver of Ctenopharyngodon idella. Journal of fisheries of china, (2014),38(8):1057-1067.(In Chinese)
[23] Yuan Gong,Zhi Luo, Qing-ling Zhu, Jia-lang Zheng, Xiao-ying Tan, Chen Qi-liang, LinYu-cong, Rong-hua Lu.Characterization and tissue distribution of leptin, leptin receptor and leptinreceptor overlapping transcript genes in yellow catfish Pelteobagrusfulvidraco. General and Comparative Endocrinology, Gen Comp Endocrinol.(2013),1;182:1-6.
[24] Ye He,Shen Dan, Xiang-fang Liang*, Rong-hua Luand H. Xiao. Genetic polymorphism of LPL and HL and the association withChinese sturgeon’s performance on formulated diet. Genetics and MolecularResearch,(2013)，12(4):4559-4566.
[25] Rong-Hua Lu, Xu-Fang Liang, Min Wang,Yi Zhou, Xiao-Li Bai, Yan He. The role of leptin in lipid metabolism in fattydegenerated hepatocytes of the grass carp Ctenopharyngodon idellus. FishPhysiol Biochem.(2012), 38(6):1759-74.
[26] Hong Ji*,Rong-hua Lu*, Zhi-guang Chang,Shang-shun Su, Gong-she Yang. PGC-1β modulates the expression of genes involvedin mitochondria function and adipogenesis during preadipocyte differentiation.Reprod Dom Anim. (2012) 47(3) :419-27. (*co-fist author)
[27] Rong-hua Lu; hong ji; zhi-guang chang;shang-shun su; gong-she yang. Mitochondrial development and the influence ofits dysfunction during rat adipocyte differentiation. Molecular BiologyReports. (2010), 37 (5):2173-2182.
[28] Rong-Hua Lu. Effects of PGC-1β on thepreadipocytes differentiation and mitochondria function in rat and its actionmechanism. PhD thesis, (2010). (In Chinese)
[29] Hong Ji; Rong-hua Lu; Zhi-guang Chang; Gong-sheYang. Biological Characters and Functions of Peroxisome Proliferator-activatedReceptor γ Coactivator-(PGC-1) Family. Chinese Journal of Biochemistry andMolecular Biology. (2010),26(7):596-603. (In Chinese)
[30] Zhi-guangChang, Rong-hua Lu, Hong Ji,Shang-shun Su, Xiao-juan Gao, Gong-she Yang.Cloning and Expressional Analysisof PGC-1β and PRC cDNA in Pig. Acta Veterinaria et Zootechnica Sinica. (2010),41(9):1068-1075.(In Chinese)
[31] Hong Ji,Yan-zi Cao, Ya-qiu Lin, Pin Liu,Rong-hua Lu, Shang-shun Su, Gong-she Yang and Oku-Hiromi. Primary cultureof grass carp preadipocyte in vitro. Acta Hydrobiologica Sinica.(2009),3(6):1226-1230.
[32]Tai-yongYu;Wei-jun Pang;Jiang-wei Wu; Rong-hua Lu;Gong-she Yang; Exogenous Leptin Inhibits Differentiation via MAPK in SwineSkeletal Myoblasts, Chinese Journal of Biotechnology, (2008), 24(1):63-67.
[33] Rong-Hua Lu, Ying Li, Li-Jie Zhang,Gong-She Yang. Effects of Baicalein on the Proliferation and Differentiation ofPig Preadipocyte. Chinese Journal of Biotechnology, (2006), 22 (6): 1002-1006.(In Chinese)
[34] Ying Li, Rong-hua Lu, Gui-fen Luo, Gong-sheYang. Effects of different cryoprotectants on the viability and biologicalcharacteristics of porcine preadipocyte. Cryobiology, (2006), 53(2): 240-247.
[35] Ying Li;Gong-she Yang; Rong-hua Lu. Effectsof different cryoprotectants on post-thaw viability of porcine preadipocyte,Journal of Molecular Cell Biology, (2006), 39(3)285-288. (In Chinese)
[36] Rong-hua Lu, Ying Li, Gong-she Yang.Effect of Different Concentration PVP on Porcine Preadipocyte Cryopreserve.Journal of Agricultural Biotechnology, (2006), 14(6): 986-987. (In Chinese)
[37] Ying Li,Gong-She Yang, Rong-Hua Lu, Shi-DuoSun. Optimal Culture Method of the Porcine Preadipocyte, Chinese Journal ofCell Biology, (2005), 27:697-700. (In Chinese)
[38] Wei-JunPang, Ying Li, Rong-Hua Lu, LiangBai, Jiang-Wei Wu, Gong-She Yang. Molecular Events during AdipocyteDifferentiation, Chinese Journal of Cell Biology, (2005), 27:497-500. (In Chinese)
[39] 盧榮華,張文雅,張玉茹,楊麗萍,王俊麗,孟曉林,聶國興*.草魚肝細胞外泌體的分離鑑定及其對肝細胞miR-122/33和免疫相關基因表達的影響,水產學報,2020,44(01):1-10.
[40] 陳延娜,盧榮華*,楊國坤,張玉茹,秦超彬,吉紅,聶國興*.黑水虻油替代豆油對草魚生長性能、抗氧化能力和腸道菌群的影響,水產學報, 2019,43(10):2241-2255.
[41] 盧榮華,吉紅,聶國興*. 脂源性外泌體的功能及其在水生動物中的研究進展,水產學報,2019,43(10):2049-2059.
獲獎榮譽
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- 2021年6月獲“2021年河南師範大學優秀碩士學位論文指導教師”稱號；
- 2021年6月在2020-2021學年指導研究生開展科技創新工作中獲“校優秀指導教師”稱號；
- 2020年6月獲“河南師範大學優秀共產黨員”榮譽稱號；
- 2019年9月獲“河南師範大學三育人”先進個人稱號；
- 2018年2月獲“河南師範大學優秀教師”稱號；
- 2017年科研論文獲河南省第四屆自然科學學術獎學術論文二等獎。
