基本介紹
- 中文名：申邦
- 畢業院校：堪薩斯大學
- 學位/學歷：博士
- 職業：教師
- 專業方向：微生物學、生物科學
- 任職院校：華中農業大學動物科學技術學院動物醫學院
個人經歷,研究方向,學術成果,榮譽獎項,
個人經歷
教育經歷
2001.09 - 2005.07， 武漢大學，生物科學專業畢業，學士
2005.08 - 2010.08， 堪薩斯大學，微生物學專業畢業，博士
工作經歷
2010.12-2014.11，華盛頓大學醫學院， 博士後。
2014.12-現在，華中農業大學教授、博士生導師。
研究方向
真核病原的致病機制、人獸共患病、基因編輯、動物疫苗
學術成果
A著作類
B論文類
Xia N, Yang J, Ye S, Zhang L, Zhou Y, Zhao J, David Sibley L, Shen B*. Functional analysis of Toxoplasma lactate dehydrogenases suggests critical roles of lactate fermentation for parasite growth in vivo. Cell Microbiol. 2017 Oct 13. doi: 10.1111/cmi.12794.
Pan M, Lyu C, Zhao J, Shen B*. Sixty Years (1957-2017) of Research on Toxoplasmosis in China-An Overview. Front Microbiol. 2017 Sep 25;8:1825. doi: 10.3389/fmicb.
Shen B*, Powell RH, Behnke MS*. QTL Mapping and CRISPR/Cas9 Editing to Identify a Drug Resistance Gene in Toxoplasma gondii. J Vis Exp. 2017 Jun 22;(124). doi: 10.3791/55185.
Shen B, Yuan Y, Cheng J, Pan M, Xia N, Zhang W, Wang Y, Zhou Y, Zhao J. Activation of chronic toxoplasmosis by transportation stress in a mouse model. Oncotarget, 2016 Dec 27;7(52):87351-87360
Shen B, Brown K, Long S, Sibley LD. Development of CRISPR/Cas9 for Efficient Genome Editing in Toxoplasma gondii. Methods Mol Biol. 2017;1498:79-103.
Wang JL, Huang SY, Behnke MS, Chen K, Shen B*, Zhu XQ*, The Past, Present, and Future of Genetic Manipulation in Toxoplasma gondii. Trends Parasitol. 2016 Jul;32(7):542-53
Zhang W, Li L, Xia N, Zhou Y, Fang R, He L, Hu M, Shen B*, Zhao J*. Analysis of the virulence determination mechanisms in a local Toxoplasma strain (T.gHB1) isolated from central China. Parasitol Res. 2016 Oct;115(10):3807-15
Wang Y, Fang R, Yuan Y, Pan M, Hu M, Zhou Y, Shen B, Zhao J*. Identification of host proteins, Spata3 and Dkk2, interacting with Toxoplasma gondii micronemal protein MIC3. Parasitol Res. 2016, 115(7):2825-35
Huang Y, He L*, Hu J, Miao XY, He P, He JW, Yu L, Ngabu Malobi, Zhou YQ, Shen B, Zhao JL*. Characterization and annotation of Babesia orientalis apicoplast genome. Parasites & Vectors. 2015 Oct 16;8(1):543.
He L, Fan LZ, Liu Q, Hu J, Miao XY, Huang Y, He P, He JW, Yu L, Muhammad K, Zhou YQ, Shen B, Zhao JL*. Identification and characterization of a novel 34 kDa merozoite protein in Babesia orientalis. Vet. Parasitol. 2015 Sep. 15;212(3-4):411-6.
Bang Shen & L David Sibley. (2014) Toxoplasma aldolase is required for metabolism but dispensable for host cell invasion. PNAS. 111(9):3567-72.
Bang Shen, Kevin Brown, Tobie D Lee & L David Sibley. (2014) Efficient gene disruption in diverse strains of Toxoplasma gondii using CRISPR/CAS9. mBio, 13;5(3):e01114-14
Bang Shen, Jeffrey S. Buguliskis, Tobie D. Lee & L. David Sibley. (2014) Functional analysis of rhomboid proteases during Toxoplasma invasion. mBio;5(5):e01795-14
Bang Shen & L David Sibley. (2012) The moving junction, a key portal to host cell invasion by apicomplexan parasites. Current Opinion in Microbiology. 15(4):449-55
Bang Shen & Joe Lutkenhaus. (2009) The conserved C-terminal tail of FtsZ is required for the septal localization and division inhibitory activity of MinCC/MinD. Molecular Microbiology. 72(2) 410-424.
Bang Shen & Joe Lutkenhaus. (2010) Examination of the interaction between FtsZ and MinCN in E. coli suggests how MinC disrupts Z rings. Molecular Microbiology. 75: 1285-1298.
Bang Shen & Joe Lutkenhaus. (2011) Differences in MinC/MinD sensitivity between polar and internal Z rings in Escherichia coli. Journal of Bacteriology. 193(2):367-76.
Sebastien Pichoff, Bang Shen, Bradley Sullivan, Joe Lutkenhaus. (2012) FtsA mutants impaired for self-interaction bypass ZipA suggesting a model in which FtsA
科研項目
1.華中農業大學引進人才啟動資金， 2015 - 2019
2.乳酸脫氫酶LDH2在弓形蟲緩殖子分化發育中的作用及調節機制 2016.01- 2019.12
3. 弓形蟲病現場診斷技術與基因缺失疫苗研究 2017.01-2020.12
4. 胞內寄生原蟲在宿主細胞內的生長發育特徵及調控機理2017.01-2020.12
榮譽獎項
1. 美國華盛頓大學Alexander & Gertrude Berg 博士後研究基金, 2011
2.美國堪薩斯大學Remi Amelunxen 傑出研究成就獎, 2010
3. 湖北省學士學位論文一等獎,2005
