基本介紹
科研項目,科研成果,
科研項目
1. 國家自然科學基金面上項目，31971197，紅平紅球菌中“硫飢餓”誘導蛋白和含硫胺基酸合成途徑的調控機制研究，2020/01-2023/12，58萬元，在研，主持；
2. 國家自然科學基金青年項目，31500086，紅平紅球菌二苯並噻吩脫硫“4S”途徑的轉錄調控研究，2016/01-2018/12，20萬元，結題，主持；
3. 浙江省公益技術套用研究項目，GF22C017578，2022/1-2024/12，10萬元，立項，主持；
4. 微生物代謝國家重點實驗室開放課題，MMLKF19-05，紅球菌屬中高效基因失活方法的建立，2019/05-2021/04，8萬元，結題，主持
科研成果
1. Xie Wenhai, hongkuan Deng, Jie Hou, Lijuan Wang*, 2021, Synthetic small regulatory RNAs in microbial metabolic engineering, Appl Microbiol Biotechnol. 105(1):1-12.
2. Wang Lijuan*, Xiaodan Gu, Xiaoxiao Li, Liang Shen*, Hongfang Ji*. Comparative analysis of heparin affecting the biochemical properties of chicken and murine prion proteins. PLoS One. 2021 Feb 18;16(2):e0247248. doi: 10.1371.
3. Wang Lijuan, Xiaoxiao Li, Jie Hou, Xinhua Song, Wenhai Xie*, Liang Shen*, 2020, Integrated analyses of mouse stem cell transcriptomes provide clues for stem cell maintenance and transdifferentiation. Front. Genet. 11:563798.
4. Li Xiaoxiao, Lijuan Wang, Jie Hou, Hongyang Liu, Rui Wang, Chao Wang, Wenhai Xie*, 2020, Identification of long noncoding RNAs as predictors of survival in triple-negative breast cancer based on network analysis. Biomed Res Int. 2020:8970340.
5. Wang Lijuan, Xiaodan Gu, Guohua Yu, Liang Shen* & Hongfang Ji*, 2018, Different effects of lipid on conformational conversion of chicken and murine prion proteins, Vet. Microbiol. 224: 1-7.
6. Wang Lijuan, Hongzhi Tang, Hao Yu, Yuxiang Yao & Ping Xu*, 2014, An unusual repressor controls the expression of a crucial nicotine-degrading gene cluster in Pseudomonas putida S16,Mol. Microbiol.91(6): 1252–1269.
7. Liu Yanghui, Lijuan Wang, Kaiming Huang, Weiwei Wang, Xueling Nie, Yi Jiang, Pengpeng Li, Shiyan Liu, Ping Xu & Hongzhi Tang*, 2014, Physiological and biochemical characterization of a novel nicotine-degrading bacterium Pseudomonas geniculata N1. PloS One9(1): e84399.
8. Hu Haiyang, Lijuan Wang, Weiwei Wang, Geng Wu, Fei Tao, Ping Xu, Zixin Deng, Hongzhi Tang, 2019, Regulatory mechanism of nicotine degradation in Pseudomonas putida. mBio. 10(3):e00602-19.
9. Tang Hongzhi, Lijuan Wang, Weiwei Wang, Hao Yu, Kunzhi Zhang, Yuxiang Yao & Ping Xu*, 2013, Systematic unraveling of the unsolved pathway of nicotine degradation in Pseudomonas. PLoS Genet. 9(10): e1003923.
10. Kong Chunlei, Lijuan Wang, Pengpeng Li, Yuanyuan Qu*, Hongzhi Tang*, Jingwei Wang, Hao Zhou, Qiao Ma, Jiti Zhou & Ping Xu, 2013, Genome sequence of Dyella ginsengisoli strain LA-4, an efficient degrader of aromatic compounds. Genome announc. 1(6): e00961-00913.
11. Tang Hongzhi, Yuxiang Yao, Dake Zhang, Xiangzhou Meng, Lijuan Wang, Hao Yu, Lanying Ma & Ping Xu*, 2011, A novel NADH-dependent and FAD-containing hydroxylase is crucial for nicotine degradation by Pseudomonas putida.J. Biol. Chem. 286(45): 39179-39187.
12. Tang Hongzhi, Lijuan Wang, Xiangzhou Meng, Lanying Ma, Shuning Wang, Xiaofei He, Geng Wu & Ping Xu*, 2009, Novel nicotine oxidoreductase-encoding gene involved in nicotine degradation by Pseudomonas putida strain S16. Appl. Environ. Microbiol. 75(3): 772-778.
13. Yao Yuxiang, Hongzhi Tang, Huixue Ren, Hao Yu, Lijuan Wang, Wen Zhang, E. J. Behrman & Ping Xu*, 2013, Iron (II)-dependent dioxygenase and N-formylamide deformylase catalyze the reactions from 5-hydroxy-2-pyridone to maleamate. Sci. Rep. 3: 3235.
14. Tang Hongzhi, Yuxiang Yao, Lijuan Wang, Hao Yu, Yiling Ren, Geng Wu & Ping Xu*, 2012, Genomic analysis of Pseudomonas putida: genes in a genome island are crucial for nicotine degradation. Sci. Rep. 2: 337.
15. Tang Hongzhi, Hao Yu, Cui Tai, Kaiming Huang, Yanghui Liu, Lijuan Wang, Yu Yao, Geng Wu & Ping Xu*, 2012, Genome sequence of a novel nicotine-degrading strain, Pseudomonas geniculata N1. J. Bacteriol. 194(13): 3553-3554.
16. Yao Yuxiang, Hongzhi Tang*, Huixue Ren, Hao Yu, Lijuan Wang & Ping Xu*, 2012, Genome sequence of a nicotine-degrading strain of Arthrobacter. J. Bacteriol. 194(20): 5714-5715.
17. Yu Hao, Hongzhi Tang, Lijuan Wang, Yuxiang Yao, Geng Wu & Ping Xu*, 2011, Complete genome sequence of the nicotine-degrading Pseudomonas putida strain S16. J. Bacteriol. 193(19): 5541-5542.
