王麗娟(浙江工業大學副研究員)

王麗娟(浙江工業大學副研究員)

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王麗娟,女,博士,浙江工業大學副研究員,碩士生導師,主要從事微生物代謝工程方面的基礎研究、產業套用和環境微生物中有機污染物分解代謝相關基因的轉錄調控機制研究。

基本介紹

科研項目,科研成果,

科研項目

1. 國家自然科學基金面上項目,31971197,紅平紅球菌中“硫飢餓”誘導蛋白和含硫胺基酸合成途徑的調控機制研究,2020/01-2023/12,58萬元,在研,主持;
2. 國家自然科學基金青年項目,31500086,紅平紅球菌二苯並噻吩脫硫“4S”途徑的轉錄調控研究,2016/01-2018/12,20萬元,結題,主持;
3. 浙江省公益技術套用研究項目,GF22C017578,2022/1-2024/12,10萬元,立項,主持;
4. 微生物代謝國家重點實驗室開放課題,MMLKF19-05,紅球菌屬中高效基因失活方法的建立,2019/05-2021/04,8萬元,結題,主持

科研成果

1. Xie Wenhai, hongkuan Deng, Jie Hou, Lijuan Wang*, 2021, Synthetic small regulatory RNAs in microbial metabolic engineering, Appl Microbiol Biotechnol. 105(1):1-12.
2. Wang Lijuan*, Xiaodan Gu, Xiaoxiao Li, Liang Shen*, Hongfang Ji*. Comparative analysis of heparin affecting the biochemical properties of chicken and murine prion proteins. PLoS One. 2021 Feb 18;16(2):e0247248. doi: 10.1371.
3. Wang Lijuan, Xiaoxiao Li, Jie Hou, Xinhua Song, Wenhai Xie*, Liang Shen*, 2020, Integrated analyses of mouse stem cell transcriptomes provide clues for stem cell maintenance and transdifferentiation. Front. Genet. 11:563798.
4. Li Xiaoxiao, Lijuan Wang, Jie Hou, Hongyang Liu, Rui Wang, Chao Wang, Wenhai Xie*, 2020, Identification of long noncoding RNAs as predictors of survival in triple-negative breast cancer based on network analysis. Biomed Res Int. 2020:8970340.
5. Wang Lijuan, Xiaodan Gu, Guohua Yu, Liang Shen* & Hongfang Ji*, 2018, Different effects of lipid on conformational conversion of chicken and murine prion proteins, Vet. Microbiol. 224: 1-7.
6. Wang Lijuan, Hongzhi Tang, Hao Yu, Yuxiang Yao & Ping Xu*, 2014, An unusual repressor controls the expression of a crucial nicotine-degrading gene cluster in Pseudomonas putida S16,Mol. Microbiol.91(6): 1252–1269.
7. Liu Yanghui, Lijuan Wang, Kaiming Huang, Weiwei Wang, Xueling Nie, Yi Jiang, Pengpeng Li, Shiyan Liu, Ping Xu & Hongzhi Tang*, 2014, Physiological and biochemical characterization of a novel nicotine-degrading bacterium Pseudomonas geniculata N1. PloS One9(1): e84399.
8. Hu Haiyang, Lijuan Wang, Weiwei Wang, Geng Wu, Fei Tao, Ping Xu, Zixin Deng, Hongzhi Tang, 2019, Regulatory mechanism of nicotine degradation in Pseudomonas putida. mBio. 10(3):e00602-19.
9. Tang Hongzhi, Lijuan Wang, Weiwei Wang, Hao Yu, Kunzhi Zhang, Yuxiang Yao & Ping Xu*, 2013, Systematic unraveling of the unsolved pathway of nicotine degradation in Pseudomonas. PLoS Genet. 9(10): e1003923.
10. Kong Chunlei, Lijuan Wang, Pengpeng Li, Yuanyuan Qu*, Hongzhi Tang*, Jingwei Wang, Hao Zhou, Qiao Ma, Jiti Zhou & Ping Xu, 2013, Genome sequence of Dyella ginsengisoli strain LA-4, an efficient degrader of aromatic compounds. Genome announc. 1(6): e00961-00913.
11. Tang Hongzhi, Yuxiang Yao, Dake Zhang, Xiangzhou Meng, Lijuan Wang, Hao Yu, Lanying Ma & Ping Xu*, 2011, A novel NADH-dependent and FAD-containing hydroxylase is crucial for nicotine degradation by Pseudomonas putida.J. Biol. Chem. 286(45): 39179-39187.
12. Tang Hongzhi, Lijuan Wang, Xiangzhou Meng, Lanying Ma, Shuning Wang, Xiaofei He, Geng Wu & Ping Xu*, 2009, Novel nicotine oxidoreductase-encoding gene involved in nicotine degradation by Pseudomonas putida strain S16. Appl. Environ. Microbiol. 75(3): 772-778.
13. Yao Yuxiang, Hongzhi Tang, Huixue Ren, Hao Yu, Lijuan Wang, Wen Zhang, E. J. Behrman & Ping Xu*, 2013, Iron (II)-dependent dioxygenase and N-formylamide deformylase catalyze the reactions from 5-hydroxy-2-pyridone to maleamate. Sci. Rep. 3: 3235.
14. Tang Hongzhi, Yuxiang Yao, Lijuan Wang, Hao Yu, Yiling Ren, Geng Wu & Ping Xu*, 2012, Genomic analysis of Pseudomonas putida: genes in a genome island are crucial for nicotine degradation. Sci. Rep. 2: 337.
15. Tang Hongzhi, Hao Yu, Cui Tai, Kaiming Huang, Yanghui Liu, Lijuan Wang, Yu Yao, Geng Wu & Ping Xu*, 2012, Genome sequence of a novel nicotine-degrading strain, Pseudomonas geniculata N1. J. Bacteriol. 194(13): 3553-3554.
16. Yao Yuxiang, Hongzhi Tang*, Huixue Ren, Hao Yu, Lijuan Wang & Ping Xu*, 2012, Genome sequence of a nicotine-degrading strain of Arthrobacter. J. Bacteriol. 194(20): 5714-5715.
17. Yu Hao, Hongzhi Tang, Lijuan Wang, Yuxiang Yao, Geng Wu & Ping Xu*, 2011, Complete genome sequence of the nicotine-degrading Pseudomonas putida strain S16. J. Bacteriol. 193(19): 5541-5542.

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