王興龍，男，山東成武，博士研究生，副教授，碩士生導師。西北農林科技大學動物醫學院家畜傳染病學主講教師，動物疫病防控與淨化團隊骨幹成員；國家絨毛用羊細菌病研究室成員；陝西省家兔產業技術體系崗位疫病防控專家；國家自然科學基金委員會生命科學部評議專家。
基本介紹
- 中文名：王興龍
- 畢業院校：南京農業大學
- 學位/學歷：博士
- 職業：教師
- 專業方向：預防獸醫
- 任職院校：西北農林科技大學
- 籍貫：山東成武
- 性別：男
人物經歷,研究方向,開設課程,代表論文,發明專利,科研項目,榮譽獎項,
人物經歷
2005年6月畢業於南京農業大學動物醫學院動物醫學專業，獲農學學士學位
2010年6月畢業於南京農業大學動物醫學院預防獸醫學專業（傳染病防治方向），獲農學博士學位（碩博連讀）
2010年7月至2014年12月在西北農林科技大學動物醫學院預防獸醫系做動物傳染病防治研究工作，講師
2014年7月至2015年6月在英國愛丁堡大學羅斯林研究所（University of Edinburgh, RoslinInsititue博士後）。
2015年1月至在西北農林科技大學動物醫學院預防獸醫系做動物傳染病防治研究工作，副教授（破格晉升）
研究方向
科研方向：動物傳染病防治。
基礎理論研究：豬繁殖與呼吸綜合徵轉錄與調控機制研究；
套用研究：腺病毒載體疫苗開發與利用。
開設課程
獸醫傳染病學，豬病學
代表論文
第一作者論文：
1.Wang, Xinglong# ,Jia, Yanqing , Wang, Xiangwei , Wang, Chongyang , Lv, Changjie , Li, Xiaoqin , Chu, Zhili , Han, Qingsong , Xiao, Sa , Zhang, Shuxia , Yang, Zengqi. MiR-375 Has Contrasting Effects on Newcastle Disease Virus Growth Depending on the Target Gene. International Journal of Biological Sciences. 2019, 15. 44-57. 10.7150/ijbs.25106.
2.Xinglong Wang#, Qiuxia Tang#, Li Qiu, ZengqiYang,Penton-dodecahedron of fowl adenovirus serotype 4 as a vaccine candidate for the control of related diseases,Vaccine, 2019,37(6),839-847,
3.. Wang Xinglong# ;LvChangjie; JiXiaojuan; Wang Bin; Qiu Li; Yang Zengqi ,(*). Ivermectin treatment inhibits the replication of Porcine circovirus 2 (PCV2) in vitro and mitigates the impact of viral infection in piglets. , Virus Research, 2019.263:80~86
4.. Wang Xinglong #, Dang Ruiyi, Yang Zengqi. The interferon antagonistic activities of the V proteins of NDV correlated with their virulence. Virus Genes 2019.
5.Xinglong Wang#, Qiuxia Tang#, Zhili Chu, Peixin Wang, Chen Luo, Yajie Zhang, Xiaoyu Fang, Li Qiu, Ruyi Dang, Zengqi Yang,Immune protection efficacy of FAdV-4 surface proteins fiber-1, fiber-2, hexon and penton base,Virus Research, 245,2018,1-6,
6. Wang, Xinglong#, Xiangwei Wang, YanqingJia, Chongyang Wang, Qinsong Han, Zen H. Lu, and Zengqi Yang. "Adenoviral-expressed recombinant granulocyte monocyte colony-stimulating factor (GM-CSF) enhances protective immunity induced by inactivated Newcastle Disease Virus (NDV) vaccine."Antiviral Research, 2017.
7. Wang, Xinglong#, ShanhuiRen, Xiangwei Wang, Chong Yang Wang, Mengfei Fan, YanqingJia, XiaolongGao, Huan Liu, Sa Xiao, and Zengqi Yang. "Genomic characterization of a wild-bird-origin pigeon paramyxovirus type 1 (PPMV-1) first isolated in the northwest region of China."Archives of virology,2017,162,(3):749-761.
8.Xiangwei Wang#, Xinglong Wang#, YanqingJia, Chongyang Wang, Qiuxia Tang, Qingsong Han, Sa Xiao, and Zengqi Yang. Journal of Interferon , Cytokine Research 2017, 37:10, 467-473 2.419
9.Wang, Xinglong#, Zhenbing Wang, HongyuXu, Biao Xiang, Ruiyi Dang, and Zengqi Yang. "Orally Administrated Whole Yeast Vaccine Against Porcine Epidemic Diarrhea Virus Induced High Levels of IgA Response in Mice and Piglets."Viral immunology,2016,29 (9): 526-531.
10.Wang, Xinglong#, Guohui Mu, Ruiyi Dang, and Zengqi Yang. "Up-regulation of IL-10 upon PRRSV vaccination impacts on the immune response against CSFV."Veterinary microbiology2016,197: 68-71.
11.Wang, Xinglong#, Zhenbin Wang, HongyuXu, Xiang Biao, and Zengqi Yang. "A single amino acid substitution alter antigenicity of Glycosylated protein 4 of HP-PRRSV."Virology journal.2016,13(1): 129.
12.Wang Xinglong# ,Qui Li, Dang Yu, XiaoSha, Zhang Shuxia, Yang Zengqi（*）.Linear Epitope Recognition Antibodies Strongly Respond to the C-terminal Domain of HP-PRRSV GP5 [J]. Veterinary Microbiology, 2014, 174(3-4):565–569.
13.WangXinglong#, Dang Ruyi, Liu Wenkai, Yang Zengqi（*）, Enqi Du, Shuxia Zhang.
Antigenic characteristics of glycosylated protein 3 of highly pathogenic porcine reproductive and respiratory syndrome virus[J]. Virus research, 2014, 189: 24-28.
14.WangXinglong#, Wang Jinqiu, HaoHuafang,Qiu Li, Liu Haijing, Chen Shengli, Dang Ruyi, Yang Zengqi（*）. Pathogenic Providenciaalcalifaciens Strain that Causes Fatal Hemorrhagic Pneumonia in Piglets[J]. Current microbiology, 2014, 68(3): 278-284.
15. Wang Xinglong#, HaoHuafang, QiuLi, Dang Ruyi, Du Enqi,ZhangShuxia, Yang Zengqi（*）.
Phylogenetic analysis of rabbit hemorrhagic disease virus in China and the antigenic variation of new strains[J]. Archives of virology, 2012, 157(8): 1523-1530.
16.Wang Xinglong#, QiuLi, HaoHuafang, Zhang Weidong, Fu Xiangjing, Zhang Hongling, He Shengfang, Zhang Shuxia, Du Enqi, Zengqi Yang（*）. Adenovirus-based oral vaccine for rabbit hemorrhagic disease[J]. Veterinary immunology and immunopathology, 2012, 145(1): 277-282.
17.WangXinglong#,Junxing Li , JiangPing , LiYufeng,ZeshanBasit, Cao Jun , WangXianwei.. GM-CSF fused with GP3 and GP5 of porcine reproductive and respiratory syndrome virus increased the immune responses and protective efficacy against virulent PRRSV challenge. 2009. Virus research. 143. 24-32
18. Li, Yufeng#, Wang, Xinglong#,Bo Kuntao , WangXianwei , TangBo , YangBaoshou , Jiang Wenming , Jiang Ping. Emergence of a highly pathogenic porcine reproductive and respiratory syndrome virus in the Mid-Eastern region of China. Veterinary journal. 2007.174. 577-84.
通訊作者論文：
1. Xiaoqin Li, YanqingJia, Haijin Liu, Xiangwei Wang, Zhili Chu, Ruochen Hu, Juan Ren, Sa Xiao, Shuxia Zhang, Xinglong Wang*,Zengqi Yang*,High level expression of ISG12(1) promotes cell apoptosis via mitochondrial-dependent pathway and so as to hinder Newcastle disease virus replication, Veterinary Microbiology, 2019, 228,147-156,
2. Qingsong Han, XiaolongGao, Zhili Chu, Xiangwei Wang, FathalrhmanEisaAddoma Adam, Shuxia Zhang, YanqingJia, XinxinQiu, Xinglong Wang*,Zengqi Yang*,Truncated chicken MDA5 enhances the immune response to inactivated NDV vaccine,Veterinary Immunology and Immunopathology,2019, 208, 44-52,
3.Zhili Chu, Caiying Wang, Qiuxia Tang, Xiaolei Shi, XiaolongGao, Jiangang Ma, Kejia Lu, Qingsong Han, YanqingJia, Xiangwei Wang, FathalrhmanEisaAddoma Adam, Haijin Liu, Sa Xiao,Xinglong Wang*,Zengqi Yang*. Newcastle Disease Virus V Protein Inhibits Cell Apoptosis and Promotes Viral Replication by Targeting CacyBP/SIP.Frontiers in cellular and infection microbiology, 2018; 8: 304.. doi:10.3389/fcimb.2018.00304 3.520
4. (2) LvChangjie ; Liu Wenkai; Wang Bin; Dang Ruyi; Qiu Li; Ren Juan; Yan Chuanqi; Yang Zengqi *, Wang Xinglong*.Ivermectin inhibits DNA polymerase UL42 of pseudorabies virus entrance into the nucleus and proliferation of the virus in vitro and vivo , Antiviral Research, 2018.11, 159: 55~62
5. Ren, Shanhui; Wang, Chongyang; Zhang, Xue; Zhao, Lei; Wang, Xiangwei; Yao, Wei; Han, Qingsong; Wang, Yanhong; Fan, Mengfe; Gao, Xiaolong; Xiao, Sa; Wang, Xinglong*; Yang, Zengqi*. Phylogenetic and pathogenic characterization of a pigeon paramyxovirus type 1 isolate reveals cross-species transmission and potential outbreak risks in the northwest region of China. Archives of Virology, 2017.1-13.
6. ShanhuiRen, XiumeiXie, Yanping Wang, Lina Tong, XiaolongGao, YanqingJia, Haixin Wang, Mengfei Fan, Shuxia Zhang, Sa Xiao,Xinglong Wang*, Zengqi Yang*. Molecular characterization of a Class I Newcastle disease virus strain isolated from a pigeon in China.″ Avian Pathology, 2016,45(4): 408-417.
7. Wenkai Liu Ruyi Dang ,Xinglong Wang*.Development of a SYBR-based real-time PCR to detect rabbit hemorrhagic disease virus (RHDV) and analyze its tissue distribution in experimentally infected rabbits[J]. VirologicaSinica,2015, 30(3): 228-230.
8．Xiao Li, Li Qiu, Zengqi Yang（*）, Ruiyi Dang and Xinglong Wang（*）. Emergency vaccination alleviates highly pathogenic porcine reproductive and respiratory syndrome virus infection after contact exposure[J]. BMC veterinary research, 2013, 9(1): 26. 2.
發明專利
(1) 王興龍 ,楊增岐，王相偉。一種利用表達GM-CSF的腺病毒提高新城疫滅活疫苗免疫效果的方法及試劑盒, 2016.08.09, 中國, 20160648941.5 (專利)
科研項目
國家級項目：
1.十三五重點研發計畫子課題：大熊貓與虎重要疫病診斷與檢測技術研究。2017.1-2020.12，32萬元
2.國家自然基金青年基金項目面上項目：PRRSV利用多變B-TRS高效轉錄亞基因組的獨特機制研究.2017.1-2020.12, 64萬元
3.國家自然基金青年基金項目：高效轉導豬源細胞腺病毒Pt-Dd的篩選及其對豬亞單位疫苗免疫增強作. 2014.1-2016.12，22萬元
省部級項目：
1.陝西省科技攻關項目：兔出血熱病毒的流行病學調查及重組腺病毒疫苗研究.陝西省科技攻關2014.1-2015.12，10萬元，結題
校級及企業項目：
1.鴿副黏病毒和腺病毒二聯疫苗開發和利用，企業合作， 2018.6-2019.6，5萬元。
2.豬重要疫病病原抗原開發和利用，企業合作，2019.1-2019.12，12萬元。
3.中央高校基本科研業務經費：PRRSV 誘導Treg發生分子基礎的研究.中央高校基本科研業務經費2011.10-2014.10. 10萬元，已結題。
榮譽獎項
2011年教育部科技進步二等獎（排名12）。
2015年西北農林科技大學青年教師講課比賽三等獎，西北農林科技大學動物醫學院青年教師講課比賽一等獎。
2016年動物醫學院青年教師講課比賽二等獎。
2016、2018年，全國大學生“生泰杯”專業技能大賽優秀培訓教師。
2012、2017、2018年，西北農林科技大學動物醫學院考核優秀。
