王祖勇(湖南大學材料科學與工程學院教授)

王祖勇，男，1984年1月出生，江蘇鹽城人，博士， 湖南大學材料科學與工程學院教授，博士生導師，湖南大學“嶽麓學者”晨星B崗。

基本介紹

• 中文名：王祖勇
• 國籍：中國
• 畢業院校：新加坡國立大學
• 學位/學歷：博士
• 專業方向：材料科學與工程學
• 任職院校：湖南大學

人物經歷

教育經歷

2009.8-2013.12 博士 新加坡國立大學 （導師：Teoh Swee Hin, Hong Minghui, Thian Eng San, and Chan Kok Yen Jerry）

2006.9-2009.7 碩士 廈門大學(導師：任磊)

2002.9-2006.7 本科 吉林大學(導師：房學迅)

工作經歷

2017.1-至今 副教授湖南大學材料科學與工程學院非金屬材料與工程系

2014.2-2017.1 博士後研究員 新加坡國立大學生物醫用材料與套用中心

2013.9-2014.2 研究員助理 新加坡國立大學光學科學與工程中心

2012.2-2012.3 訪問學者 日本京都工業纖維大學

學術兼職

Materials Technology: Advanced Performance Materials, Assistant Editor

Journal of Physics: Materials, Bio-Responsive Materials, Co-Guest Editor

中國生物醫學工程學會，高級會員

擔任Elsevier、RSC、ACS和Bentham Science等集團期刊審稿人

研究領域

圍繞生物材料的大尺度、可控微納製造技術和功能進行探索，主要研究方向包括：

纖維增材製造

醫用支架與人體軟組織工程

柔性健康器件

學術成果

期刊論文

Ting Lei, Wanqi Zhang, Hu Qian, Poon Nian Lim, Eng SanThian, Pengfei Lei, Yihe Hu, ZuyongWang. Silicon-incorporated nanohydroxyapatite-reinforced poly(ε-caprolactone) film to enhance osteogenesis for bone tissue engineering applications. Colloids and Surfaces B: Biointerfaces. 2019, doi: 10.1016/j.colsurfb.2019.110714

Wanqi Zhang, Zuyong Wang*, Chao Xie, Xianwei Wang, Fangfang Luo, Minghui Hong, Rui Zhou, Chao Ma, Nan Lin, Jieyu Zhang, Xuefeng Hu*, Jerry Kok Yen Chan, Feng Wen*, Yunbing Wang. Scaffold with micro/macro‐architecture for myocardial alignment engineering into complex 3D cell patterns. Advanced Healthcare Materials. 2019, 8(19): 201901015

Zuyong Wang#,*, Wanqi Zhang#, Chao Xie#, Feng Wen, Chao Ma, Nan Lin, Eng San Thian, Xianwei Wang*. Geometric anisotropy on biomaterials surface for vascular scaffold design: engineering and biological advances. Journal of Physics: Materials. 2019, 2(3): 032003 (Invited Paper)

Jieyu Zhang, Xian Jiang, Xiang Wen, Qian Xu, Hao Zeng, Yuxing Zhao, Min Liu, Zuyong Wang, Xuefeng Hu*, Yunbing Wang*. Bio-responsive smart polymers and biomedical applications. Journal of Physics: Materials. 2019, 2(3): 032004 (Invited Paper)

Zuyong Wang*, Won Jae Lee, Bryan Thean Howe Koh, Minghui Hong, Wilson Wang, Poon Nian Lim, Jason Feng, Lisa Soyeon Park, Michael Kim, Eng San Thian*. Functional regeneration of tendons using scaffolds with physical anisotropy engineered via microarchitectural manipulation. Science Advances. 2018, 4: eaat4537

Dong Wang, Chris Steffi, Zuyong Wang, Chee Hoe Kong, Poon Nian Lim, Zhilong Shi, Eng San Thian, Wilson Wang. Beta-cyclodextrin modified mesoporous bioactive glass nanoparticles/silk fibroin hybrid nanofibers as an implantable estradiol delivery system for the potential treatment of osteoporosis. Nanoscale. 2018, DOI: 10.1039/C8NR05268A

Chris Steffi, Dong Wang, Chee Hoe Kong, Zuyong Wang, Poon Nian Lim, Zhilong Shi, Eng San Thian, Wilson Wang. Estradiol-loaded poly(ε-caprolactone)/silk fibroin electrospun microfibers decrease osteoclast activity and retain osteoblast function. ACS Applied Materials & Interfaces. 2018, 10(12): 9988–9998

Zuyong Wang*, Rui Zhou, Feng Wen, Rongkai Zhang, Lei Ren, Swee Hin Teoh, Minghui Hong*. Reliable laser fabrication: the quest for responsive biomaterials surface. Journal of Materials Chemistry B. 2018, 6(22): 3612-3631

Poon Nian Lim, Toshiisa Konishi, Zuyong Wang, Jason Feng, Jing Han, Zhijie Yang, Eng San Thian. Enhancing osteoconductivity and biocompatibility of silver-substituted apatite in-vivo through silicon co-substitution. Materials Letters. 2018, 212(00): 90-93

Kaichen Xu#, Zuyong Wang#, Chuan Fu Tan, Ning Kang, Lianwei Chen, Lei Ren, Eng San Thian, Ghim Wei Ho, Rong Ji, Minghui Hong. Uniaxially stretched flexible surface plasmon resonance film for versatile surface enhanced raman scattering diagnostics. ACS Applied Materials & Interfaces. 2017, 9(31): 26341-26349

Zuyong Wang, Feng Wen, Rongkai Zhang, Qinyuan Zhang. Modulated nitric oxide delivery in three-dimensional biomaterials for vascular functionality. MRS Communications. 2017, 7(3): 348-360 (Invited Paper)

Poon Nian Lim, Zuyong Wang, Dong Wang, Toshiisa Konishi, Eng San Thian. Development in additive printing for musculoskeletal tissue engineering-bone and tendon. Current Opinion in Biomedical Engineering. 2017, 2: 99-104 (New Journal, Invited Paper)

Zuyong Wang, Feng Wen, Poon Nian Lim, Qinyuan Zhang, Toshiisa Konishi, Dong Wang, Swee Hin Teoh, Eng San Thian. Nanomaterial scaffolds to regenerate musculoskeletal tissue: signals from within for neovessel formation. Drug Discovery Today. 2017, 22(9): 1385-1391 (Invited Paper)

Poon Nian Lim, Jason Feng, Zuyong Wang, Mark Chong, Toshiisa Konishi, Lay Geok Tan, Jerry Chan, Eng San Thian. In-vivo evaluation of subcutaneously implanted cell-Loaded apatite microcarriers for osteogenic potency. Journal of Materials Science: Materials in Medicine. 2017, 28(6): 86

Shi Yun Tong#, Zuyong Wang#,*, Poon Nian Lim, Wilson Wang, Eng San Thian*. Uniformly-dispersed nanohydroxapatite-reinforced poly(epsilon-caprolactone) composite films for tendon tissue engineering application. Materials Science and Engineering C: Materials for Biological Applications. 2017, 70(Pt 2): 1149-1155 (Invited Paper)

Poon Nian Lim, Zuyong Wang, Lei Chang, Toshiisa Konishi, Cleo Choong, Bow Ho, Eng San Thian. A multi-material coating containing chemically-modified apatites for combined enhanced bioactivity and reduced infection via a drop-on-demand micro-dispensing technique. Journal of Materials Science: Materials in Medicine. 2017, 28(1): 3

Yang Wu#, Zuyong Wang#, Ying Hsi Jerry Fuh, San Yoke Wong, Wilson Wang, Eng San Thian. Direct E-jet printing of three-dimensional fibrous scaffold for tendon tissue engineering. Journal of Biomedical Materials Research Part B: Applied Biomaterials. 2017, 105(3): 616–627

Yang Wu, Zuyong Wang, Jerry Ying His Fuh, Yoke San Wong, Wilson Wang, Eng San Thian. Mechanically-enhanced three-dimensional scaffold with anisotropic morphology for tendon regeneration. Journal of Materials Science: Materials in Medicine. 2016, 27(7): 115 (Covered Paper)

Zuyong Wang, Zheren Du, Jerry Kok Yen Chan, Swee Hin Teoh, Eng San Thian, Minghui Hong. Direct laser microperforation of bioresponsive surface-patterned films with through-hole arrays for vascular tissue-tngineering application. ACS Biomaterials-Science & Engineering. 2015, 1(12): 1239-1249

Zuyong Wang, Swee Hin Teoh, Minghui Hong, Fangfang Luo, Yiling Erin Teo, Jerry Kok Yen Chan, Eng San Thian. Dual-mcrostructured porous, anisotropic film for biomimicking of endothelial basement membrane. ACS Applied Materials & Interfaces. 2015, 7(24): 13445-13456

Qinyuan Zhang, Zuyong Wang, Feng Wen, Lei Ren, Jun Li, Swee Hin Teoh, Eng San Thian. Gelatin-siloxane nanoparticles to deliver nitric oxide for vascular cell regulation: synthesis, cytocompatibility, and cellular responses. Journal of Biomedical Materials Research Part A. 2015, 103(3): 929-938

Youyong Yuan, Zuyong Wang, Pingqiang Cai, Jie Liu, Lun-De Liao, Minghui Hong, Xiaodong Chen, Nitish Thakor, Bin Liu. Conjugated polymer and drug co-encapsulated nanoparticles for chemo- and photo-thermal combination therapy with two-photon regulated fast drug release. Nanoscale. 2015, 7: 3067-3076

Zuyong Wang, Swee Hin Teoh, Nuryanti Binti Johana, Mark Seow Khoon Chong, Erin Yiling Teo, Minghui Hong, Jerry Kok Yen Chan, Eng San Thian. Enhancing mesenchymal stem cell response using uniaxially stretched poly(epsilon-caprolactone) film micropatterns for vascular tissue engineering application. Journal of Materials Chemistry B. 2014, 2: 5898-5909.

Zuyong Wang, Jing Lim, Yeow Siong Ho, Qinyuan Zhang, Mark Seow Khoon Chong, Min Tang, Minhui Hong, Jerry Kok Yen Chan, Swee Hin Teoh, Eng San Thian. Biomimetic three-dimensional anisotropic geometries by uniaxial stretching of poly(epsilon-caprolactone) films: degradation and mesenchymal stem cell responses. Journal of Biomedical Materials Research Part A. 2014, 102A: 2197-2207

Zuyong Wang, Erin Yiling Teo, Mark Seow Khoon Chong, Qinyuan Zhang, Jing Lim, Zhiyong Zhang, Minghui Hong, Eng San Thian, Jerry Kok Yen Chan, Swee Hin Teoh. Biomimetic three-dimensional anisotropic geometries by uniaxial stretch of poly(epsilon-caprolactone) films for mesenchymal stem cell proliferation, alignment, and myogenic differentiation. Tissue Engineering Part C: Methods. 2013, 19(7): 538-549 (Featured Press, Immediate Release News)

Zuyong Wang#, Yang Zhao#, Lei Ren, Lihua Jin, Liping Sun, Pei Yin, Yafei Zhang, Qiqing Zhang. Novel gelatin-siloxane nanoparticles decorated by Tat peptide as vectors for gene therapy. Nanotechnology. 2008, 19(44): 445103

授權專利

1. Eng San Thian*, Zuyong Wang, Yi Min Tan, Bow Ho. A Packaging Material and Method of Preparation Thereof. 9/1/2017, Singapore, 10201610373X (Approved), PCT/SG2017/050605, WO 2018/106191 A1 (Approved)

2. Eng San Thian*, Zuyong Wang, Wilson Wang, Minghui Hong. Tissue Scaffold Device and Method for Fabricating Thereof. 3/11/2015, Singapore, PCT/SG2015/050431, US Patent 15/526,429, European Patent 15859055.4 (Approved)

3. Swee Hin Teoh*, Zuyong Wang, Erin Y. Teo, Jerry K.Y. Chan, Mark S.K. Chong, Zhiyong Zhang, Chuen Neng Lee, Minghui Hong. Method to Produce Unique Discontinuous 3D Topolographical Cues on Bioresorbable Polymeric Film via Uni-Axial Stretching Below the Melting Temperature for Cell Alignment, Proliferation and Differentiation in Tissue Engineering Applications. 9/3/2011, US Patent, 61/541,201 (Application)

4. 任磊*, 張亞菲, 印佩, 王祖勇, 王軍, 張其清. 基於羧甲基殼聚糖的基因遞送載體及其製備方法和套用. 26/12/2008, 福建, CN200810072485.X（申請）

5. 任磊*；趙陽；王祖勇；張其清, 一種用於基因遞送的載體及其製備方法和套用, 29/5/2008, 福建, CN200810071151.0（授權）

獎勵榮譽

國家優秀自費留學生獎學金 國家留學基金委 中國 2013

優秀海報獎（Rapid Fire） 9th世界生物材料大會中國 2012

KIT iTech交流項目獎學金 日本文部科學省JASSO 日本 2012

新加坡教育局/國立大學研究獎學金 新加坡國立大學 新加坡2009-2013