王廣鳳，女，博士，新加坡國立大學化學與生物工程系博士後（2012-2013），教授，博士生導師。
承擔《分析化學》、《生命分析化學》等本科生、研究生課程的教學任務。
長期從事環境健康分析的研究工作，以第一/通訊作者在Nat. Commun., Adv. Funct. Mater., Adv. Healthc. Mater., Anal. Chem.等期刊發表學術論文50餘篇。先後主持國家自然科學基金、安徽省傑出青年基金等項目。曾獲國務院政府特殊津貼、安徽省“五一勞動獎章”、“皖江學者特聘教授”、教育部自然科學二等獎及安徽省自然科學二等獎，擔任安徽省檢測檢驗學會常務理事。
基本介紹
- 中文名：王廣鳳
- 學位/學歷：博士
- 職業：教師
- 專業方向：納米材料組裝
- 任職院校：安徽師範大學
- 性別：女
個人經歷,主講課程,研究方向,學術成果,榮譽獎項,
個人經歷
工作經歷
2005年至今，安徽師範大學化學與材料科學院 教師
2012年－2013年，新加坡國立大學化學與生物工程系博士後研究員 (Research Fellow)
主講課程
1.分析化學（I）
2. 化學化工文獻信息檢索
3.無機及分析化學
4.基礎化學實驗
5.綜合化學實驗
研究方向
1.納米材料組裝：可控合成與組裝新型功能化金屬、半導體、碳材料及量子點等材料，套用於環境、食品及生物分析等領域。
2. 環境毒性感測研究：對環境污染物如金屬離子、持久性有機污染物的毒性機制及感測技術研究。
3. 光/電生物感測器構建：對生命標誌物、病毒DNA及其他疾病相關生物分子的檢測。
學術成果
主持項目
9.“DNA-金屬螢光納米材料的製備及其無標記放大檢測轉錄因子的套用研究”（國家自然科學基金, 2017-2020主持）
8.“DNA-金屬納米簇基目標誘導信號放大生物感測”（安徽省自然科學基金,2016-2018,主持）
7.“DNA-金屬納米簇基生物感測器的構建及套用研究”（高校領軍人才引進與培育計畫項目,2016-2017,主持）
6.“基於DNA構象變化的生物電化學感測器研究”（化學生物感測與計量學國家重點實驗室開放基金, 2014-2017, 主持）
5.“生物小分子輔助法製備雙功能石墨烯複合材料及其在電化學免疫感測器中的套用研究”（安徽省自然科學基金,2013-2014主持）
4. “金納米摻雜石墨烯構築生物分子固定界面及其電化學免疫感測器的套用”(國家自然科學基金,2010-2012, 主持)
3.“銅屬納米材料的可控合成及其與導電聚合物的界面作用在糖尿病檢測中的套用”（合肥工業大學安徽省可控化學與材料化工重點實驗室開放基金,2010-2011, 主持）
2.“磁性納米複合材料修飾電極的製備及其在無酶測定中的套用”（安徽省教育廳自然科學基金,2009,主持）
- “稀土納米化合物的製備及其修飾電極作為生物感測器的套用研究”（安徽省高等學校青年教師科研資助計畫項目,2006-2007, 主持）
代表性論文
38.Cuiting Liu,Baojuan Wang,Ting Han,Dongmin Shi, andGuangfeng Wang* Fe Foil-Guided Fabrication of Uniform Ag@AgX Nanowires for Sensitive Detection of Leukemia DNA, ACSAppl. Mater. Interfaces, 2019, 11 (5), 4820-4825
37. Ting Han,Guangfeng Wang*Peroxidase-like activity of acetylcholine-basedcolorimetric detection of acetylcholinesteraseactivity and an organophosphorusinhibitor,J. Mater. Chem. B.In press
36.Xinsheng Yang,Dongmin Shi,Shengmei Zhu,Baojuan Wang,Xiaojun Zhang, andGuangfeng Wang*,Portable Aptasensor of Aflatoxin B1 in Bread Based on a Personal Glucose Meter and DNA Walking Machine, ACS Sens., 2018, 3 (7), 1368-1375
35.WangGuangfeng*,WanJing,Zhang Xiaojun,TTE DNA–Cu NPs: enhanced fluorescence and application in a target DNA triggered dual-cycle amplification biosensor,Chemical Communications, 2017, 53, 5629--5632
34.Sheng Feifan, Zhang Xiaojun,Wang Guangfeng*,Novel ultrasensitive homogeneous electrochemical aptasensor based on dsDNA-templated copper nanoparticles for the detection of ractopamine,J. Mater. Chem. B, 2017,5, 53-613.
33.HongLu,ZhouFu , Dongmin Shia, Xiaojun Zhang,Guangfeng Wang*,Portable aptamer biosensor of platelet-derived growth factor-BB using apersonal glucose meter with triply amplified,Biosensors and Bioelectronics, 2017, 95, 152–159
32.Hong Lu, Zhou Fu,Wang Guangfeng*, Zhang Xiaojun,Synthesis and sensing integration: A novel enzymatic reaction modulated Nanoclusters Beacon (NCB) “Illumination” strategy for label-free biosensing and logic gate operation,Biosensors and Bioelectronics,2016, 86, 588-594
31.Jiang Hong, ZhangXiaojun,Wang Guangfeng*,[G3T]5/Tbbased DNA biosensor with target DNA-triggered autocatalytic multi-cycle-amplification and magnetic nanoparticles assisted-background-lowered,Biosensors and Bioelectronics, 2015, 74, 931-938
30.Sha, Liang,Zhang Xiaojun,Wang, Guangfeng*,A label-free and enzyme-free ultra-sensitive transcription factors biosensor using DNA-templated copper nanoparticles as fluorescent indicator and hairpin DNA cascade reaction as signal amplifier,Biosensors and Bioelectronics,2016, 82, 85–92,
29.Shi Dongmin, Sun Yue, Lin Lin, Shi Chunjun,Wang Guangfeng*, Zhang, Xiaojun,Naked-eye sensitive detection of alkaline phosphatase (ALP) and pyrophosphate (PPi) based on a horseradish peroxidase catalytic colorimetric system with Cu(II),Analyst, 2016, 141, 5549
28.Lin Lin,Sh Dongmin, Li Quanfa,Wang Guangfeng*, Zhang Xiaojun,Detection of T4 polynucleotide kinase based on a MnO2 nanosheet-3,3',5,5' -tetramethylbenzidine (TMB) colorimetric system,Anal. Methods, 2016, 8, 4119
27.Xiong Yunfang,Lin Lin, Zhang Xiaojun,Wang Guangfeng*,Label-free electrochemiluminescent detection of transcription factors with hybridization chain reaction amplificationRSC Adv., 2016, 6, 37681
26.Hong Lu, Wan Jing, Zhang Xiaojun,Wang Guangfeng*,DNA–gold nanoparticles network based electrochemical biosensors for DNA MTase activity,Talanta2016,152, 228–235
25,Chen Ling, Sha Liang, Qiu Yuwei,Wang Guangfeng*, Zhang Xiaojun, An amplified electrochemical aptasensor based on hybridization chain reactions and catalysis of silver nanoclusters,Nanoscale,2015, (7): 3300-3308
24.Jiang Hong,Wang Guangfeng*,Zhang Xiaojun,Detection of heparin based on the conformational switch of DNA,Anal. Methods, 2015,7, 7852-7857
23.Zhu Yanhong,Wang Guangfeng*, Sha Liang, Qiu Yuwei ,Jiang Hong, Zhang Xiaojun,A ratiometric colorimetric detection of the folate receptor based on terminal protection of small-molecule-linked DNAAnalyst, 2015,140, 1260-1264
22.Jiang Hong,XuGang, SunYimin, ZhengWeiwei,ZhuXiangxiang,WangBaojuan, ZhangXiaojun,Wang Guangfeng*,A "turn-on" silver nanocluster based fluorescentsensor for folate receptor detection and cancer cellimaging under visual analysis,Chemical Communications, 2015, 51: 11810-11813
21.Zhu Yanhong,Wang Guangfeng*, Jiang Hong, Chen Ling, Zhang Xiaojun, One-step ultrasonic synthesis of graphene quantum dots with high quantum yield and their application in sensing alkaline phosphatase,Chemical Communications, 2015, 51(5): 948-951
20.Wang, Guangfeng*, Xu, Gang, Zhu, Yanhong, Zhang, Xiaojun*, Aturn-on'' carbon nanotube-Ag nanoclusters fluorescent sensor for sensitive and selective detection of Hg2+ with cyclic amplification of exonuclease III activity,Chemical Communications, 2014, 50(6): 747-750
19.Wang Guangfeng*, HuangHao, Wang Baojuan, Zhang Xiaojun, Wang Lun*, A supersandwich multienzyme-DNA label based electrochemical immunosensor,Chemical Communications, 2012, 48 (5): 720-722
18.Wang, Guangfeng*, Zhu, Yanhong, Chen, Ling, Zhang, Xiaojun, Photoinduced electron transfer (PET) based label-free aptasensor for platelet-derived growth factor-BB and its logic gate application,Biosensors and Bioelectronics, 2015, 63: 552-557
17.Xu, Gang,Wang, Guangfeng*, Zhu, Yanhong, Chen, Ling, He, Xiuping, Wang, Lun, Zhang, Xiaojun, Amplified and selective detection of Agions based on electrically contacted enzymes on duplex-like DNA scaffolds,Biosensors and Bioelectronics,2014, 59: 269-275
16.Wang, Guangfeng*, Chen, Ling, Zhu, Yanhong, He, Xiuping, Xu, Gang, Zhang, Xiaojun,Development of an electrochemical sensor based on the catalysis of ferrocene actuated hemin/G-quadruplex enzyme for the detection of potassium ions,Biosensors and Bioelectronics, 2014, 61: 410-416
15.Wang, Guangfeng*, He, Xiuping, Wang, Lun, Zhang, Xiaojun, A folate receptor electrochemical sensor based on terminal protection and supersandwich DNAzyme amplification,Biosensors and Bioelectronics,2013, 42: 337-341
14.Wang, Guangfeng*, He, Xiuping, Xu, Gang, Chen, Ling, Zhu, Yanhong, Zhang, Xiaojun, Wang, Lun, Detection of T4 polynucleotide kinase activity with immobilization of TiO2 nanotubes and amplification of Au nanoparticles,Biosensors and Bioelectronics, 2013, 43: 125-130
13.Wang, Guangfeng*, He, Xiuping, Chen, Ling, Zhu, Yanhong, Zhang, Xiaojun*, Wang, Lun, Conformational switch for cisplatin with hemin/G-quadruplex DNAzyme supersandwich structure,Biosensors and Bioelectronics, 2013, 50: 210-216
12.Wang, Guangfeng, Huang, Hao, Zhang, Xiaojun, Wang, Lun*, Electrically contacted enzyme based on dual hairpin DNA structure and its application for amplified detection of Hg,Biosensors and Bioelectronics, 2012, 35(1): 108-114
11.He, Xiuping,Wang, Guangfeng*, Xu, Gang, Zhu, Yanhong, Chen, Ling, Zhang, Xiaojun, A Simple, Fast, and Sensitive Assay for the Detection of DNA, Thrombin, and Adenosine Triphosphate Based on Dual-Hairpin DNA Structure,Langmuir, 2013, 29 (46): 14328-14334
10.Wang, Guangfeng*, Huang, Hao, Zhang, Ge, Zhang, Xiaojun, Fang, Bin, Wang, Lun, Dual Amplification Strategy for the Fabrication of Highly Sensitive Interleukin-6 Amperometric Immunosensor Based on Poly-Dopamine,Langmuir, 2011, 27(3): 1224-1231
9.Wang, Guangfeng*, Chen, Ling, Zhu, Yanhong, He, Xiuping, Xu, Gang, Zhang, Xiaojun, Prussian blue-Au nanocomposites actuated hemin/G-quadruplexes catalysis for amplified detection of DNA, Hg2+ and adenosine triphosphate,Analyst, 2014, 139(20): 5297-5303
8.Wang, Guangfeng*, Chen, Ling, He, Xiuping, Zhu, Yanhong, Zhang, Xiaojun*, Detection of polynucleotide kinase activity by using a gold electrode modified with magnetic microspheres coated with titanium dioxide nanoparticles and a DNA dendrimer,Analyst, 2014, 139(16): 3895-3900
7.Wang, Guangfeng*, Zhu, Yanhong, Chen, Ling, Wang, Lun, Zhang, Xiaojun, Target-induced quenching for highly sensitive detection of nucleic acids based on label-free luminescent supersandwich DNA/silver nanoclusters,Analyst, 2014, 139(1): 165-169
6.Xu, Gang,Wang, Guangfeng*, He, Xiuping, Zhu, Yanhong, Chen, Ling, Zhang, Xiaojun, An ultrasensitive electrochemical method for detection of Ag+ based on cyclic amplification of exonuclease III activity on cytosine-Ag+-cytosine,Analyst, 2013, 138(22): 6900-6906
5.Wang, Guangfeng*, He, Xiuping, Wang, Baojuan, Zhang, Xiaojun, Wang, Lun, Electrochemical amplified detection of Hgbased on the supersandwich DNA structure,Analyst, 2012, 137(9): 2036-2038
4.Wang, Guangfeng*, Zhu, Yanhong, Chen, Ling, Zhang, Xiaojun, Dual hairpin-like molecular beacon based on coralyne-adenosine interaction for sensing melamine in dairy products,Talanta, 2014, 129: 398-403
3.Wang, Guangfeng*, Gang, Xu, Zhou, Xuan, Zhang, Ge, Huang, Hao, Zhang, Xiaojun, Wang, Lun, Electrochemical immunosensor with graphene/gold nanoparticles platform and ferrocene derivatives label,Talanta, 2013, 103:75-80
2.Wang, Guangfeng*, Chen, Ling, Zhu, Yanhong, Wang, Lun, Zhang, Xiaojun, Adenosine Triphosphate Sensing by Electrocatalysis with DNAzyme,Electroanalysis, 2014, 26(2): 312-318
1.Wang, Guangfeng*, He, Xiuping, Zhu, Yanhong, Chen, Ling, Wang, Lun, Zhang, Xiaojun, G-Quadruplex-Linked Supersandwich DNA Structure for Electrochemical Amplified Detection of Thrombin,Electroanalysis, 2013, 25(8): 1960-1966
榮譽獎項
1.2016年, 教育部高校科學研究自然科學獎, 二等獎(排名第一)
2.2016年,安徽省自然科學獎, 二等獎(排名第一)
3. 2013年, 安徽省“省級教壇新秀”
4.2008年, 安徽省教學成果獎, 一等獎 (排名第四)
5.2008年, 安徽省自然科學獎, 三等獎 (排名第四)
6.2021年12月，被確定為第八批安徽省學術和技術帶頭人。
2022年3月4日，入選“安徽省五一勞動獎章”候選人名單。
