滕兆乾,男,博士,研究員,博士生導師,幹細胞與腦損傷修復研究組組長。
基本信息,個人簡歷,研究領域,代表論著,
基本信息
姓 名: 滕兆乾
學 科: 幹細胞與腦損傷修復研究組
通訊地址: 北京市海淀區北四環西路25-1號
中國科學院動物研究所幹細胞與生殖生物學國家重點實驗室
個人簡歷
2005年博士畢業於中國科學院動物研究所,2005至2013年先後在中國農業大學、美國新墨西哥大學醫學院、路易斯安娜州立大學健康科學中心做博士後,主要從事神經發生與腦損傷方面的研究。2014年起,在美國約翰霍普金斯大學醫學院做Research Associate。2015年入選中科院百人計畫。研究成果發表在 Cell、 Cell Stem Cell、Neuron、Stem Cells、 Cell Reports、 Journal of Neuroscience、Journal of Cerebral Blood Flow and Metabolism 等國際學術期刊上
研究領域
研究工作主要集中在腦損傷的發病機理、神經發生的分子調控、以及幹細胞在腦損傷修復中的套用研究。研究組的主要研究方向包括:(1)腦損傷後,大腦內環境變化對神經發生與神經再生影響的分子機理;(2)慢性創傷性腦病的分子致病機制;(3)探索通過幹細胞移植和改善神經再生與可塑性內環境而實現腦損科研項目
1. 2015-2017 中國科學院“百人計畫”,主持,在研
2. 2016-2019 國家自然科學基金面上項目,主持,在研
代表論著
Jian Zhang, Zhao-Qian Teng, Yunping Song, Mei Hu, Chu Chen. Inhibition of monoacylglycerol lipase prevents chronic traumatic encephalopathy-like neuropathology in a mouse model of repetitive mild closed head injury. J Cereb Blood Flow Metab
Jian Zhang, Mei Hu, Zhao-Qian Teng, Yunping Song, Chu Chen. Synaptic and Cognitive Improvements by Inhibition of 2-AG Metabolism Are through Upregulation of MicroRNA-188-3p in a Mouse Model of Alzheimer's Disease
Rongqing Chen*, Jian Zhang*, Ni Fan*, Zhao-Qian Teng*, Yan Wu*, Hongwei Yang, YaPing Tang, Hao Sun, Yunping Song, Chu Chen. 2013. Δ9-THC-Caused Synaptic and Memory Impairments Are Mediated through COX-2 Signaling
Changmei Liu, Zhao-Qian Teng, Andrea L McQuate, Emily M Jobe, Christa C Christ, Sergei J von Hoyningen-Huene, Marie D Reyes, Eric D Polich, Yina Xing, Yue Li, Weixiang Guo, Xinyu Zhao. 2013. An Epigenetic Feedback Regulatory Loop Involving MicroRNA195 and MBD1 Governs Neural Stem Cell Differentiation
Rongqing Chen, Jian Zhang, Yan Wu, Dongqing Wang, Guoping Feng, Ya-Ping Tang, Zhao-Qian Teng, Chu Chen. 2012. Monoacylglycerol Lipase Is a Therapeutic Target for Alzheimer's Disease
Manavendra Pathania, Juan Torres-Reveron, Lily Yan, Tomoki Kimura, Tiffany V Lin, Valerie Gordon, Zhao-Qian Teng, Xinyu Zhao, Tudor A Fulga, David Van Vactor, Angélique Bordey. 2012. miR-132 enhances dendritic morphogenesis, spine density, synaptic integration, and survival of newborn olfactory bulb neurons
Weixiang Guo, Li Zhang, Devin M. Christopher, Zhao-Qian Teng, Sarah R. Fausett, Changmei Liu, Olivia L. George, John Klingensmith, Peng Jin, Xinyu Zhao. 2011. RNA binding protein FXR2 regulates proliferation and differentiation of adult hippocampal neural stem cells by repressing Noggin expression
Changmei Liu*, Zhao-Qian Teng*, Nicholas J. Santistevan, Keith E. Szulwach, Weixiang Guo, Peng Jin, Xinyu Zhao. 2010. Epigenetic Regulation of miR-184 by MBD1 Governs Neural Stem Cell Proliferation and Differentiation
Richard D. Smrt, Keith E. Szulwach, Rebecca L. Pfeiffer, Xuekun Li, Weixiang Guo, Manavendra Pathania, Zhao-Qian Teng, Yuping Luo, Junmin Peng, Angelique Bordey, Peng Jin, Xinyu Zhao. 2010. MicroRNA miR-137 Regulates Neuronal Maturation by Targeting Ubiquitin Ligase Mind Bomb-1