楊有軍，男，博士，華東理工大學藥學院教授，博士生導師。
基本介紹
- 中文名：楊有軍
- 學位/學歷：博士
- 職業：教師
- 專業方向：藥化、藥理、藥劑、藥物化學生物學等
- 任職院校：華東理工大學藥學院
個人經歷,研究方向,學術成果,榮譽獎項,
個人經歷
2015-現在 | 華東理工大學藥學院 | 教授/博導 |
2010-2015 | 華東理工大學藥學院 | 副教授/博導 |
2007-2010 | 德克薩斯大學奧斯汀分校 | 博士後（導師:Eric V. Anslyn教授） |
2002-2007 | 美國路易斯安那州立大學 | 博士（導師:Robert M. Strongin教授） |
1997-2002 | 中國科技大學 | 本科（導師:王官武教授） |
研究方向
學術成果
通過三年或五年的培養，學生在分子設計（物理有機化學）、化學合成、光譜測試分析（紫外可見吸收光譜、穩態與瞬態螢光光譜）、生物顯微成像（單光子/雙光子共聚焦顯微成像、PALM/STORM/STED/SIM等各類超分辨成像技術）、藥物化學生物學（活性分子控制釋放、生物螢光標記、藥物先導化合物發現）等方面有較好的積累。
研究工作獲得基金委、市科委、市教委等單位的資助，成果發表在JACS（4篇）、Angew、PNAS、Anal. Chem.（5篇）、Org. Lett.、Chem. Comm.、J. Org. Chem.等本領域高影響期刊。
論文發表：
18. Haihong He, Yuxin Liu, Zhongneng Zhou, Chunlei Guo, Hong-Yin Wang, Zhuang Wang, Xueli Wang, Ziqian Zhang, Fu-Gen Wu, Haolu Wang, Daijie Chen, Dahai Yang, Xiaowen Liang,* Jinquan Chen,* Shengmin Zhou,* Xin Liang,* Xuhong Qian, Youjun Yang.*A Photo-Triggered and Photo-Calibrated Nitric Oxide Donor: Rational Design, Spectral Characterizations, and Biological Applications.Free Radical Biol. Med.
17. Xiao Luo, Haotian Yang, Haolu Wang, Zhiwei Ye, Zhongneng Zhou, Luyan Gu, JinquanChen ,Yi Xiao, Xiaowen Liang*, Xuhong Qian, and Youjun Yang*.Highly Sensitive Hill-Type Small-Molecule pH Probe That Recognizes the Reversed pH Gradient of Cancer Cells.Anal. Chem.
16. Haihong He, Yuxin Liu, Zhongneng Zhou, Yang Xia, Yingxue Qi, Zhuang Wang, Hong-Yin Wang, Xueli Wang, Jianming Bao, Ziqian Zhang, Fu-Gen Wu, Haolu Wang, Daijie Chen, Dahai Yang, Xiaowen Liang,* Jinquan Chen,* Shengmin Zhou,* Xin Liang,* Xuhong Qian, Youjun Yang.* “Water-soluble, Green-light Triggered and Photo-Calibrated Nitric Oxide Donors for Biological Applications.”Bioconjugate Chem.
15. Haihong He, Zhiwei Ye, Ying Zheng, Xiu Xu, Chunlei Guo, Yi Xiao,* Wei Yang,* Xuhong Qian,* and Youjun Yang*. “Super-Resolution Imaging of Lysosomes with a Nitroso-Caged Rhodamine.”Chem.Commum.
14. Haihong He, Zhiwei Ye, Yi Xiao,* Wei Yang,* Xuhong Qian,* Youjun Yang*. “Super-Resolution Monitoring of Mitochondrial Dynamics upon Time-Gated Photo-Triggered Release of Nitric Oxide.”Anal.Chem.
13.ZuhaiLei, Zhenhua Zeng, Xuhong Qian,Youjun Yang*. “A novel chromogenic and fluorogenic scaffold for detection of oxidative radicals.”Chin. Chem. Lett.,
12.ZuhaiLei, Ping Yue, Xueli Wang, Xinran Li, Yi Li, Haihong He, Xiao Luo, Xiangming Meng*, Jinquan Chen*, Xuhong Qian*,Youjun Yang*. “TPZ, a bright centrosymmetric two-photon scaffold for bioimaging.”Chem. Commun.
11.ZuhaiLei, Xinran Li, Xiao Luo, Haihong He, Jing Zheng, Xuhong Qian,Youjun Yang*. “Bright, Stable and Biocompatible Organic Fluorophores Absorbing/Emitting in the Deep Near-Infrared Spectral Region.”Angew. Chem. Int. ,56, 2979-2983. Highlighted bySci. Transl. Med,
10. Ziqian Zhang, Yi Li, Haihong He, Xuhong Qian,Youjun Yang*. “Mild Chemo-TriggeredGenetrationof a Fluorophore-Tethered Diazoalkane Species via Smiles Rearrangement.”
9. Ziqian Zhang, Jiayao Wu, Zhihao Shang, Chao Wang, Jiagao Cheng, Xuhong Qian, Yi Xiao*, Zhiping Xu*,Youjun Yang.* “Photo-Calibrated NO release from N-Nitrosated Napthalimides upon One-Photon or Two-Photon Irradiation.”Anal. Chem.
8. Quanjuan Zhang, Na Zhang, Yi-Tao Long, Xuhong Qian,Youjun Yang*. “Understanding the Selectivity of a Multi-Channel Fluorescent Probe for Peroxynitrite Over Hypochlorite.”Bioconjugate Chem.
7.Zuhai, Lei; Xinran Li; Yi Li; Xiao Luo; Miaomiao Zhou;Youjun Yang*. “Synthesis of Sterically Protected Xanthene Dyes with Bulky Groups at C-3’ and C-7’.”J. Org. Chem.
6. Yanming Shen, Zhihao Shang, Yanhong Yang, Shaojia Zhu, Xuhong Qian, Ping Shi*, Jing Zheng*, andYoujun Yang*. “Structurally Rigid 9-Amino-benzo[c]cinnoliniums Make Up a Class of Compact and Large Stokes-Shift Fluorescent Dyes for Cell-Based Imaging Applications.”J. Org. Chem.,
5. Yanming Shen, Quanjuan Zhang, Xuhong Qian, andYoujun Yang*. “Practical Assay for Nitrite and Nitrosothiol as an Alternative to the Griess Assay or the 2,3-Diaminonaphthalene Assay.”Anal. Chem.,
4. Ziqian Zhang, Baoyan Zhang, Xuhong Qian, Zhong Li, Zhiping Xu*,Youjun Yang*.Simultaneous Quantification of Hgand MeHgin Aqueous Media by a Single Fluorescent Probe via Multiplexing in the Time Domain.Anal. Chem.
3. Linlin Song,ZuhaiLei, Baoyan Zhang, Zhiping Xu*, Zhong Li* andYoujun Yang*. “A Zero-Background Fluorescent Probe for HgDesigned via the Covalent-Assembly Principle.”Anal. Methods,
2. ZuhaiLei,Youjun Yang*.A concise colorimetric and fluorimetric probe for Sarin related threats designed via the covalent-assembly approach.J. Am. Chem. Soc.,Highlight inAdvances in Engineering.
1. Quanjuan Zhang, Zhichuan Zhu, Yongli Zheng, Jiagao Cheng, Na Zhang, Yi-Tao Long, Jing Zheng, Xuhong Qian, andYoujun Yang*. “A Three-Channel Fluorescent Probe That Distinguishes Peroxynitrite from Hypochlorite.”J. Am. Chem. Soc.
Below are publications from graduate and Post-doc works.
7.Youjun Yang, Balazs Szamosfalvi, Jerry Yee, Stanley Frinak and Eric V. Anslyn*. “Development of an online citrate/Casensing system for dialysis,”Analyst,
6.Youjun Yang, Stephanie K. Seidlits, Michelle M. Adams, Vincent M. Lynch, Christine E. Schmidt, Eric V. Anslyn*, Jason B. Shear*. “A highly selectivelow backgroundfluorescent imaging agent for nitric oxide,”J. Am. Chem. Soc.,
5.Youjun Yang, Mark Lowry, Xiangyang Xu, Jorge O. Escobedo, Martha Sibrian -Vazquez, Lisa Wong, Corin M. Schowalter, Timothy J. Jensen, Frank R. Fronczek, Isiah M. Warner, Robert M. Strongin*. “Seminaphthofluorones are a family of water-soluble, low molecular weight, NIR-emitting fluorophores,”Proc. Natl. Acad. Sci. USA2008,Highlights in Chemical and Engineering News, “Near-IR Imaging Goes Further”, September
4.Youjun Yang, Mark Lowry, Corin M. Schowalter, Sayo O. Fakayode, Jorge O. Escobedo, Xiangyang Xu, Huating Zhang, Timothy J. Jensen, Frank R. Fronczek, Isiah M. Warner, Robert M. Strongin*.“An organic white light-emitting fluorophore,”J. Am. Chem. Soc.,(Addition and Correction)J. Am. Chem. Soc.,Highlights in Biophotonics International, “Fluorophores Emit White Light”, December issue and in Photonics Spectra, “White Light Emitting Fluorophore has Solid State Applications”, January
3.Youjun Yang, Jorge O. Escobedo, Alexander Wong, Corin M. Schowalter, Michael C. Touchy, Lijuan Jiao, William E. Crowe, Frank R. Fronczek, Robert M. Strongin*.“A convenient preparation of xanthene dyes,”J. Org. Chem.
2. Youjun Yang, Patrick T. Lewis, Jorge. O. Escobedo, Nadia N. St. Luce, Dale W. Treleaven, Robert L. Cook, Robert M. Strongin*. “Mild Colorimetric Detection of Sialic Acid”,Coll. Czech. Chem. Comms.
1. Guan-Wu Wang*, Li-Juan Jiao, Er-Hong Hao, Yu-Ming Lu, You-Jun Yang. “Aggregation properties of an amphiphilicmethanofullerenederivative in THF-H2O solvent mixtures”,Chin. Chem. Letts.
榮譽獎項
2018年 | 自然科學基金委 | 優秀青年基金 |
2018年 | MSMLG2018 | Czarnik Emerging Investigator Award |
2017年 | 華東理工大學 | 校長獎 |
2013年 | 上海市科委 | 青年科技啟明星 |
2013年 | 華東理工大學 | 研究生課程優秀任課教師一等獎 |
2012年 | 華東理工大學 | 藥學院優秀青年教師 |
2012年 | 華東理工大學 | 天鼎東嶽獎教金特等獎 |
