基本介紹
個人簡介,工作經歷,研究方向,主要成就,發表文章,
個人簡介
李稼，教授，研究員，1984年畢業於北京醫科大學。
工作經歷
1984-1995在北京安貞醫院小兒心臟內科工作，1995至英國倫敦皇家Brompton醫院深造。
先後在成人先天性心臟病和先天性心臟病解剖學界世界著名專家DrJane Summerville 和 Prof Robert Anderson指導下工作。後在英國帝國理工學院獲博士學位。博士研究課題為兒童體外循環術後全身氧運輸平衡。2002-2013她在加拿大任助教授及副教授，並將呼吸質譜創造性地運用到試驗和臨床研究中。呼吸質譜研究全身氧運輸為該領域提供了金標準數據，發表了大量關於全身氧運輸的論文。
研究方向
危重患兒和高原患兒的病理生理研究
主要成就
全面地開展科研項目，與院內、院外及國際多箇中心合作，取得了豐碩的成果，獲得國家自然科學基金一項、首都特色研究基金一項，所級在研課題一項。發表19篇論文，其中sci文章15篇，醫學書籍1部。
國家自然科學基金、首都臨床特色套用領域與成果推廣
發表文章
1. Zhang G, Holtby H, Cai S, Al Radi O, Li J. Aortic atresia is associated with an inferior postoperative systemic, cerebral and splanchnic oxygen transport status in neonates with hypoplastic left heart syndrome after the Norwood procedure. Eur J Cardiothorac Surg. 2011 39(3):113-21.
2. Yu X, Konstantinov IE, KantochMJ, Rebeyka IM, Li J.Dynamic changes of myocardial oxygen consumption at pacing increased heart rate -- First observation by the continuous measurement of systemic oxygen consumption. ScandCardiovasc J. 2011 Oct;45(5):301-6.
3. ZhangG, SCai, Li J. Hyperglycaemia is negatively associated with systemic and cerebral oxygen transport in neonates after the Norwood procedure. Cardiol Young .2012,22 (1):49-56.
4. Dhillon S, Yu X, Zhang G, Holtby H, Cai S, Li J. The relationship between plasma concentrations of ionized calcium and magnesium with cardiac energetics and systemic oxygen transport in neonates after the Norwood procedure. J ThoracCardiovasc Surg. 2012 Aug;144(2):474-9.
5.Yu X, Larsen B, Urschel S, Cheung PY, Ross DB, Rebeyka I, West L, Li J. The profile of inflammatory and metabolic response in children undergoing heart transplantation.Clin Transplant. 2012 Mar-Apr;26(2)
6. Gill RS, Cheung PY, Yu X, Aklabi MA, Nagendran J, Quinonez LG, Li YQ, Miller J, Ross DB, Rebeyka IM, Li J. β3-adrenoceptor antagonistSR59230A attenuates the imbalance of systemic oxygen transport induced by dopamine in newborn lambs. Clin Med Insights Cardiol. 2012;6:45-51
7. Li J. Systemic oxygen transport derived by using continuous measured oxygen consumption after the Norwood procedure-an interim review. Interact CardiovascThorac Surg. 2012 Jul;15(1):93-101. (Invited review)
8. Yu X, Larsen B, Rutledge J, West L, Ross DB, Rebeyka IM, Buchholz H, Li J.The profile of systemic inflammatory response in children undergoing ventricular assist device support. Interact CardiovascThorac Surg. 2012 Sep;15(3):426-31.
9. J Li. Accurate measurement of oxygen consumption in children undergoing cardiac catheterization. Catheter CardiovascInterv. 2013 Jan 1;81(1):125-32.
10. Zhou Z, Malhotra SP, Yu X, Rutledge J, Rebeyka IM, Ross DB, Rausch C, Gu H, McCrindle B, Lacour-Gayet F, Ivy D, Li J. Moderate altitude is not associated with adverse postoperative outcomes for patients undergoing bidirectional cavopulmonary anastomosis and Fontan operation: A comparative study among Denver, Edmonton, and Toronto. J ThoracCardiovasc Surg. 2013 Nov;146(5):1165-71
11. Cheypesh A, Yu X, Li J. Measurement of systemic oxygen consumption in patients during extracorporeal membrane oxygenation-- Description of a new method and the first clinical observations. Perfusion. 2014;29(1):57-62
12. Li X, Robertson CM, Yu X, Cheypesh A, Dinu IA, Li J. Early postoperative systemic inflammatory response is an important determinant for adverse two-year neurodevelopmental outcomesafter the Norwood procedure. J Thoracic Cardiovascular Surgery. 2014 Jul;148(1):202-6
13. Liyan Zhang, Xiaoyang Yu, AndriyCheypesh, Ivan M Rebeyka, Don Granoski, Gary D. Lopaschuk ,Li J. Plasma fatty acids levels in children during extracorporeal membrane oxygenation support-- A pilot study. J Extra Corpor Technol. 2013;45(4):242
14. ZhuomingXu, Mingjie Zhang, Limin Zhu, Xiaolei Gong, Li J. Elevated plasma B-type natriuretic peptide and C-reactive protein levels in children with restrictive right ventricular physiology following tetralogy of Fallot repair. Congenit Heart Dis. 2014 Nov;9(6):521-8.
15. Qi HY, Ma RY, Jiang LX, Li SP, Mai S, Chen H, Ge M, Wang MY, Liu HN, Cai YH, Xu SY, Li J.Cardiopulmonary changes in healthy children residing at high altitude in china. JACC Cardiovasc Imaging. 2014 Dec;7(12):1281-3.
16. 李稼. 先天性心臟病患兒體外循環術後的神經系統發育異常：術前、術中及術後的影響因素.《中華實用兒科臨床雜誌》2014;29(18):1368-71
17. SantokhDhillon, Xiaoyang, Gencheng Zhang, Sally Cai, Jia Li. Clinical Hemodynamic Parameters Do Not Accurately Reflect Systemic Oxygen Transport in Neonates after the Norwood Procedure. Congenit Heart Dis. 2015 May;10(3):234-9
18. SantokhDhillon, Xiaoyang, Gencheng Zhang, David B Ross, Jia LiComparison of Profiles of Perioperative Serum C-Reactive Protein Levels in Neonates Undergoing the Norwood Procedure or Arterial Switch Operation.Congenit Heart Dis. 2015 May;10(3):226-33.
19. Qi HY, Ma RY, Jiang LX, Li SP, Mai S, Chen H, Ge M, Wang MY, Liu HN, Cai YH, Xu SY, Li J. Anatomical and hemodynamic evaluations of the heart and pulmonary arterial pressure in healthy children residing at high altitude in China. IJC Heart & Vasculature 2015;7:158–164
20. Xiaohui Li, Xiaoyang Yu, AndriyCheypesh, Jia Li. Non-invasive measurements of energy expenditure and respiratory quotient by respiratory mass spectrometry in children on extracorporeal membrane oxygenation—A pilot study. Artif Organs. 2015 Sep;39(9):815-9.
21. 齊海英,徐素雅,馬如雁,蔣麗霞,李淑萍,買抒,陳宏,葛梅,王美英,劉海寧,蔡越紅,李稼.中國高原地區與平原地區兒童心臟解剖和功能以及肺循環血液動力學的比較.中華心血管病雜誌,2015,43(9):774-781.
22. 韓丁, 劉亞光, 賈清彥, 馬駿，羅毅，李稼，歐陽川. 氯胺酮與七氟醚麻醉誘導對先天性心臟病患兒血流動力學的影響. 臨床麻醉學雜誌, 2015, 31(9): 846-849.
23. 何琛, 韓丁, 劉亞光, 賈清彥, 馬駿，羅毅，李稼，歐陽川. 全憑七氟烷吸入麻醉誘導對先天性心臟病患兒血流動力學的影響. 中國醫藥, 2015, 10(10): 1427-1430.
24. 裴馨, 韓丁, 劉亞光, 賈清彥, 馬駿，羅毅，李稼，歐陽川. 不同麻醉誘導方法對小兒室間隔缺損修補術中血流動力學影響的對比研究. 心肺血管病雜誌, 2015, 34(10): 759-763.
25. 韓丁, 羅毅, 賈清彥, 汪曉南, 李稼, 歐陽川. 壓力記錄分析法用於小兒法洛四聯症根治術中循環能量效率研究. 心肺血管病雜誌, 2016, 35(8): 40-44.
26. Ding Han, Hui Zhang, Bai-Yu Tian, Yan Zhu, Dan Zhang, Yue Li, Yi-Chao Teng, Hong Gu, XuMeng, Yi Luo, De-Ming Zhu and Jia Li. Validation of EGOS-600 Near Infrared Spectroscopy to Measure Cerebral Oxygen Saturation by Comparing to NIRO-200nx In Vitro and In Vivo. J ClinExpCardiolog 2016, 7:5
27. Adaptation of cardioupulmonary system in children at high altitude—The Chinese observations. Scholar’s press.OmniScriptum GmbH & Co. Kg. Germany。 2015（論著）
