基本介紹
- 中文名:徐昕紅
- 畢業院校:復旦大學
- 學位/學歷:博士
- 職業:教師
- 專業方向:睡眠與失眠機制
- 就職院校:復旦大學基礎醫學院
個人經歷,研究方向,學術成果,論文,參編,參與項目,
個人經歷
徐昕紅,醫學博士,副教授。畢業於上海醫科大學藥學院藥理學專業,獲理學士學位;同年起,留校任教。2005-2007年,日本大阪生命科學研究所分子行為生物學部門,任合作研究員。2010年1月,獲復旦大學醫學博士學位。
研究方向
睡眠與失眠機制
學術成果
論文
(*, 共同第一作者)
1. Xu Q, Xu XH*, Qu WM, Lazarus M, Urade Y, Huang ZL*, A mouse model mimicking human first night effect for the evaluation of hypnotics. Pharmacol Biochem Behav, 2014; 116:129-136.
2.Xu XH, Qiu MH, Dong H, Qu WM, Urade Y, Huang ZL. GABA transporter-1 inhibitor NO-711 alters the EEG power spectra and enhances non-rapid eye movement sleep during the active phase in mice. Eur Neuropsychopharmacol.; 2014;24(4):585-94.
3.Xu XH, Qu WM, Bian MJ, Huang F, Fei J, Urade Y, Huang ZL. Essential Roles of GABA Transporter-1 in Controlling Rapid Eye Movement Sleep and in Increased Slow Wave Activity after Sleep Deprivation. PLoS One. 2013 Oct 14;8(10):e75823.
4.Liu Z*, Xu XH*, Liu TY, Hong ZY, Urade Y, Huang ZL, Qu WM. Safranal Enhances Non-Rapid Eye Movement Sleep in Pentobarbital-Treated Mice. CNS Neurosci Ther. 2012,18(8):623-630.
5.Liu XG, Zhang BJ, Xu XH, Huang ZL and Qu WM, Lesions of suprachiasmatic nucleus modify sleep structure but do not alter the total amount of daily sleep in rats, Sleep Biol Rhythm, 2012,10:293-301.
6.Yan MM, Xu XH,Huang ZL,Yao MH, Urade Y and Qu WM,Selection of optimal epoch duration in assessment of rodent sleep–wake profiles,Sleep Biol Rhythm, 2011,9:46-55.
7.Qu WM*, Xu XH*, Yan MM, Wang YQ,Urade Y, Huang ZL. Essential role of dopamine D2 receptor in the maintenance of wakefulness, but not in homeostatic regulation of sleep, in mice. J Neurosci 2010; 30 (12): 4382-4389.
8.Qu WM, Huang ZL, Xu XH, Aritake K, Eguchi N, Nambu F, Narumiya S, Urade Y, Hayaishi O. Lipocalin-type prostaglandin D synthase produces prostaglandin D2 involved in regulation of physiological sleep. Proc Natl Acad Sci USA. (美國科學院院刊)2006;103(47):17949-54.
9.Qu WM, Huang ZL, Xu XH, Matsumoto N, Urade Y: Dopaminergic D1 and D2 receptors are essential for the arousal effect of modafinil. J Neurosci 2008,28(34):8462-8469.
10.Qiu MH, Qu WM, Xu XH, Yan MM, Urade Y, Huang ZL. D1/D2 receptor-targeting L-stepholidine, an active ingredient of the Chinese herb Stephonia, induces non-rapid eye movement sleep in mice. Pharmacol Biochem Behav. 2009; 94(1):16-23.
11.Qu WM, Huang ZL, Matsumoto N, Xu XH, Urade Y: Drug delivery through a chronically implanted stomach catheter improves efficiency of evaluating wake-promoting components. J Neurosci Methods. 2008; 175(1):58-63.
12.Chen CR, Qu WM, Qiu MH, Xu XH, Yao MH, Urade Y, Huang ZL. Modafinil exerts a dose-dependent antiepileptic effect mediated by adrenergic alpha1 and histaminergic H1 receptors in mice. Neuropharmacology.(神經藥理學) 2007; 53 (4):534-41.
13.Yu R, Xu XH, Sheng MP. Differential effects of allopregnanolone and GABA on kainite-induced lactate dehydrogenase release in cultured rat cerebral cortical cells. Acta Pharmacol Sin 2002;23(8):680-684.
參編
參編《十萬個為什麼》(第六版)、《腦內多巴胺》、《10000 個科學難題——生物學卷》、《睡眠醫學理論與實踐》(第4版中譯本)、《醫用藥理學》(第四版)、《大辭海》(醫藥科學卷)等著作6部,參編教材及參考書4部。
參與項目
主持國家自然科學基金面上項目1項,參與國家基礎研究重大項目973、上海市科委基礎重點、重點攻關及優秀學科帶頭人等科研項目9 項。