彭大鵬(華中農業大學教授)

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彭大鵬,中共黨員,華中農業大學教授,博士生導師。自工作以來,一直在科研教學第一線開展獸藥殘留食品安全的基礎理論及關鍵技術研究和高層次人才培養。破解了小分子化合物廣譜單克隆抗體難於製備的難題,發明了一系列具有完全自主智慧財產權的小分子半抗原、免疫原和包被原;創製了多種靈敏、高產、優質單克隆抗體,研發出基於這些廣譜抗體的試劑盒和試紙條產品。先後獲包括國家技術發明獎二等獎在內的十餘項國家及省部級科技獎勵;發表科研論文百餘篇。

基本介紹

  • 中文名:彭大鵬
  • 國籍中國
  • 畢業院校華中農業大學
  • 學位/學歷:博士
  • 職業:教師
  • 專業方向:獸藥殘留與食品安全
人物經歷,研究方向,獲獎記錄,發表論文,專利,

人物經歷

1996.09 - 2000.06, 湖北農學院,動物科學,農學學士
2000.09 - 2005.06, 華中農業大學,預防獸醫學專業 農學博士
2005.07-2009.12,華中農業大學 講師
2009.12-2018.11,華中農業大學 副教授
2018.11-至今,華中農業大學 教授

研究方向

自工作以來,一直在科研教學第一線開展獸藥殘留與食品安全的基礎理論及關鍵技術研究和高層次人才培養。在國家各級項目(課題)的資助下,破解了小分子化合物廣譜單克隆抗體難於製備的難題,發明了一系列具有完全自主智慧財產權的小分子半抗原、免疫原和包被原;創製了40多種靈敏、高產、優質單克隆抗體,研發出基於這些廣譜抗體的試劑盒和試紙條48種。培養碩士研究生30名,指導學生在第三屆中國“網際網路+”大學生創新創業大賽湖北省複賽中獲得創意組金獎。先後獲包括國家技術發明獎二等獎(排名第2)在內的9項國家及省部級科技獎勵;發表SCI論文52篇,其中以第一作者和通訊作者在包括Food Chemistry (IF 4.529)、Journal of Agricultural and Food Chemistry (IF 3.154)等本專業領域的Top期刊在內的國際期刊上發表SCI論文22篇,被引164次,他引130次,h-指數17。獲授權發明專利36件,制訂國家標準1項,農業部備案產品4個,專利保藏單克隆細胞株39株。

獲獎記錄

  • 2008年,特異性單克隆抗體的製備及其在主要雞傳染病鑑別診斷中的套用。教育部高等學校科學研究優秀成果獎技術發明獎,二等獎,序4.
  • 2008年,獸藥殘留檢測關鍵技術創新與配套集成研發。教育部高等學校科學研究優秀成果獎科學技術進步獎,一等獎,序5.
  • 2010年,免疫速測技術在禽病診斷與食品安全檢測中的套用。湖北省科技進步一等獎,序13.
  • 2010年,動物源性食品中糖皮質類藥物殘留檢測液相色譜-串聯質譜法。湖北省技術監督局,標準創新貢獻獎,一等獎,序6.
  • 2013年,獸藥殘留檢測方法標準研究制訂。湖北省人民政府,科學技術進步獎,一等獎,序8.
  • 2015年,獸用抗菌藥和違禁藥殘留高效檢測標準制定與產品創製。北京大北農集團,第九屆大北農科技成果獎,一等獎,序6.
  • 2015年,動物源食品有害殘留高效檢測核心試劑創製與產品研發。湖北省人民政府,技術發明獎,一等獎,序3.
  • 2016年,喹噁啉類三種獸藥的食品安全性評價與風險管控技術研究。湖北省人民政府,科技進步獎,一等獎,序4.
  • 2016年,動物源食品中主要獸藥殘留物高效檢測關鍵技術。國家技術發明獎,二等獎,序2.

發表論文

1.Dapeng Peng, Lingyan Zhang, Chen Situ, Yuanhu Pan, Yanfei Tao, Yulian Wang*, Zonghui Yuan*. Development of monoclonal antibodies and indirect competitive enzyme-Linked immunosorbent assay kits for the detection of clenbuterol and salbutamol in the tissues and products of food-producing animals. Food Anal. Methods. 2017, 10(11), DOI 10.1007/s12161-017-0925-z IF: 2.038
2.Dapeng Peng#, Zhaozhou Li#, Yulian Wang, Zhenli Liu, Feng Sheng*, Zonghui Yuan*. Enzyme-linked immunoassay based on imprinted microspheres forthe detection of sulfamethazine residue. Journal of Chromatography A, 2017, 1506, 9–17. IF: 3.981
3.Dapeng Peng, Xiya Zhang, Yulian Wang, Yuanhu Pan, Zhenli Liu, Dongmei Chen*, Feng Sheng*, Zonghui Yuan*. An immunoaffinity column for the selective purification of 3-methyl-quinoxaline-2-carboxylic acid from swine tissues and its determination by high-performance liquid chromatography with ultraviolet detection and a colloidal gold-based immunochromatographic assay. Food Chemistry. 2017, 237, 290-296. 4.529
4.Juan Wang, Yulian Wang, Yuanhu Pan, Dongmei Chen, Zhenli Liu, Liang Feng, Dapeng Peng*, Zonghui Yuan*. Preparation of a generic monoclonal antibody and development of a highly sensitive indirect competitive ELISA for the detection of phenothiazines in animal feed. Food Chemistry. 2017, 221: 1004–1013. IF: 4.529
5.Dapeng Peng#, Feng Liao#, Yuanhu Pan, Dongmei Chen, Zhenli Liu, Yulian Wang*, Zonghui Yuan*. Development a monoclonal antibody-based enzyme-linked immunosorbent assay for screening carotenoids in eggs. Food Chemistry. 2016, 202: 141-148. IF: 4.529
6.Dapeng Peng#, Liang Feng#, Yuanhu Pan, Yulian Wang, Dongmei Chen, Juan Wang, Zonghui Yuan*. Development and validation of an indirect competitive enzyme-linked immunosorbent assay for monitoring organoarsenic compounds in edible chicken, pork and feed. Food Chemistry. 2016, 197: 821-828. IF: 4.529
7.Wei Han, Yuanhu Pan, Yulian Wang, Dongmei Chen, Zhenli Liu, Qi Zhou, Liang Feng, Dapeng Peng*, Zonghui Yuan*. Development of a monoclonal antibody-based indirect competitive enzyme-linked immunosorbent assay for nitroimidazoles in edible animal tissues and feeds. Journal of Pharmaceutical and Biomedical Analysis. 2016, 120: 84-91. IF: 3.255
8.Dapeng Peng#, Wei Wei#, Yuanhu Pan, Yulian Wang, Dongmei Chen, Zhenli Liu, Xu Wang, Menghong Dai*, Zonghui Yuan*. Preparation of a monoclonal antibody against amantadine and rimantadine and development of an indirect competitive enzyme-linked immunosorbent assay for detecting the same in chicken muscle and liver. Journal of Pharmaceutical and Biomedical Analysis. 2017, 133: 56–63. IF: 3.255
9.Dapeng Peng#, Bijia Yang#, Yuanhu Pan, Yulian Wang, Dongmei Chen, Zhenli Liu, Wenxiang Yang, Yanfei Tao*, Zonghui Yuan*. Development and validation of a sensitive monoclonal antibody-based indirect competitive enzyme-linked immunosorbent assay for the determination of aflatoxin M1 levels in milk. Toxicon, 2016, 113: 18-24. IF: 1.927
10.Dapeng Peng, Liyan Zhang, Changyou Zhai, Yulian Wang, Dongmei Chen, Yanfei Tao, Yuanhu Pan, Zhenli Liu, Zonghui Yuan*. Development and validation of a monoclonal antibody-based indirect competitive ELISA for the detection of sudan I in duck eggs and crystal violet in carp. Food Analytical Methods, 2017, 10(5):1442-1451. IF: 2.038
11.Dapeng Peng, Yulian Wang, Liang Feng, Guangcai Cao, Yanfei Tao, Zhenli Liu, Zonghui Yuan*. Preparation of Broadly Specific Monoclonal Antibodies for Simultaneous Determination of Fluoroquinolone Residues in Eggs. Food Analytical Methods, 2016, 9(12):3520-3531. IF: 2.038
12.Juan Wang, Yulian Wang, Yuanhu Pan, Liang Feng, Dongmei Chen, Zhenli Liu, Dapeng Peng*, Zonghui Yuan*. Preparation of a Broadly Specific Monoclonal Antibody-Based Indirect Competitive ELISA for the Detection of Benzodiazepines in Edible Animal Tissues and Feed. Food Analytical Methods, 2016, 9(12): 3407-3419. IF: 2.038
13.Lingling An, Yulian Wang, Yuanhu Pan, Yanfei Tao, Dongmei Chen, Zhenli Liu, Wenxiang Yang, Dapeng Peng*, Zonghui Yuan*. Development and validation of a sensitive indirect competitive enzyme-Linked immunosorbent assay for the screening of florfenicol and thiamphenicol in edible animal tissue and feed. Food Analytical Methods, 2016, 9(9):2434-2443. IF: 2.038
14.Dapeng Peng#, Fangfang Chang#, Yulian Wang, Dongmei Chen, Zhenli Liu, Xiaodong Zhou, Liang Feng, Zonghui Yuan*. Development of a sensitive monoclonal-based enzyme-linked immunosorbent assay for monitoring T-2 toxin in food and feed. Food Additives & Contaminants: Part A, 2016, 33(4): 683-692 IF: 2.047
15.Dapeng Peng, Nenghui Jiang, Yulian Wang, Dongmei Chen, Zhenli Liu, Zonghui Yuan*. Development and validation of an indirect competitive enzyme-linked immunosorbent assay for the detection of albendazole 2-aminosulfone residues in animal tissues. Food and Agricultural Immunology 2016; 27(2): 273-287. IF: 1.392
16.Xiya Zhang#, Dapeng Peng#, Yuanhu Pan, Yulian Wang, Dongmei Chen, Qi Zhou, Zhenli Liu, Zonghui Yuan*. A novel hapten and monoclonal-based enzyme-linked immunosorbent assay for 3-methyl-quinoxaline-2-carboxylic acid in edible animal tissues. Analytical Methods, 2015, 7: 6588–6594. IF: 1.900
17.Qi Zhou#, Dapeng Peng#, Yulian Wang, Yuanhu Pan, Dan Wan, Xiya Zhang, Zonghui Yuan*. A novel haptene and monoclonal-based enzyme-linked immunosorbent assay for sulfonamides in edible animal tissues. Food Chemistry. 2014, 154: 52-56. IF: 4.529
18.Dapeng Peng#, Shengqiang Ye#, Yulian Wang, Dongmei Chen, Yanfei Tao, Lingli Huang, Zhenli Liu, Menghong Dai, Xiaoqing Wang, and Zonghui Yuan*. Development and validation of an indirect competitive enzyme-linked immunosorbent assay for the screening of tylosin and tilmicosin in muscle, liver, milk, honey and eggs. Journal of Agricultural and Food Chemistry, 2012, 60: 44-51. 2012 Jan 11 IF: 3.154
19.Yu Liu, Dapeng Peng, Lingli Huang, Yulian Wang, Chao Chang, Awais Ihsan, Yanfei Tao, Bo Yang, Zonghui Yuan*. Application of a modified enzyme-linked immunosorbent assay for 3-amino-2-oxazolidinone residue in aquatic animals. Analytica Chimica Acta, 2010, 664(2): 151-157. IF: 4.950
20.Chunbao Zhao#, Dapeng Peng#, Yulian Wang, Lingli Huang, Dongmei Chen, Yanfei Tao and Zonghui Yuan*. Preparation and validation of the polyclonal antibodies for detection of chlortetracycline residues. Food and Agricultural Immunology, 2008, 19(2): 163-174 IF: 1.392
21.Chang Chao#, Dapeng Peng#, Jine Wu, Yulian Wang, Zonghui Yuan*. Development of an indirect competitive ELISA for detecting furazolidone marker residue in animal edible tissues. Journal of Agricultural and Food Chemistry, 2008, 56(5): 1525-1531. IF: 3.154
22.Dapeng Peng#, Sishun Hu#, Yan Hua, Yuncai Xiao, Zili Li, Xiliang Wang, Dingren Bi*. Comparison of a new gold-immunochromatographic assay for the detection of antibodies against avian influenza virus with hemagglutination inhibition and agar gel immunodiffusion assays. Veterinary Immunology and Immunopathology, 2007, 117(1-2): 17-25. IF:1.718
23.Dapeng Peng, Zeying Zhang, Dongmei Chen, Yulian Wang, Yanfei Tao, Zonghui Yuan*. Development and validation of an indirect competitive enzyme-linked immunosorbent assay for monitoring quinoxaline-2-carboxylic acid in the edible tissues of animals. Food Additives and Contaminants: Part A, 2011, 28(11): 1524-1533. IF: 2.047

專利

1.硝基咪唑類藥物的單克隆抗體及酶聯免疫方法與試劑盒。ZL201410830051.7。序2.
2.用於檢測食品中頭孢類抗生素殘留的抗體晶片試劑盒及方法。ZL201410830203.3。序2.
3. 用於檢測食品中氨基糖苷類抗生素殘留的抗體晶片試劑盒及方法。ZL201410829545.3。序2.
4.用於檢測食品中磺胺類藥物殘留的抗體晶片試劑盒及方法。ZL201410830693.7。序2.
5.用於檢測呋喃它酮殘留標識物AMOZ的單抗及酶聯免疫方法與試劑盒。ZL201210176537.4。序2.
6.一種單克隆抗體,包含該單克隆抗體的檢測試劑盒及套用。ZL200510011521.8。序2.
7.用於檢測卡巴氧和喹賽多代謝產物的單克隆抗體及酶聯免疫方法和試劑盒。ZL201410830131.2。序3.
8.用於檢測甲睪酮的單克隆抗體及酶聯免疫方法與試劑盒。ZL201410830027.3。序3.
9.用於檢測己烯雌酚的單抗隆抗體及酶聯免疫方法和試劑盒。ZL201410830464.5。序3
10. 用於檢測雄激素類藥物的單克隆抗體及酶聯免疫方法及試劑盒。ZL201410829543.4。序3
11. 磺胺類藥物分子印跡固相萃取小柱的製備方法及套用。ZL201210049753.2。序3
12. 吉他黴素殘留檢測用基因工程抗體及製備方法和套用。ZL201210049798.X。序3
13. 磺胺二甲嘧啶分子印跡仿生識別試劑盒及製備方法和套用。ZL201210049767.4。序3
14. 呋喃西林殘留標示物氨基脲單克隆抗體及製備方法和套用。ZL201210049821.5。序3
15. 阿苯達唑-2-氨基碸殘留檢測單克隆抗體及製備方法和套用。ZL201210049837.6。序3
16. 吉他黴素殘留檢測用單克隆抗體及製備方法和套用。ZL201210049826.8。序3
17. 一種檢測磺胺類藥物殘留的膠體金試紙條及其使用方法和套用。ZL201210 177239.7。序3
18. 一種檢測新黴素的膠體金試紙條及其套用。ZL201210176424.4。序3
19. 用於檢測氟喹諾酮類藥物殘留的單克隆抗體及酶聯免疫方法與試劑盒。ZL201210176496.9。序3
20. 用於檢測阿散酸、硝苯砷酸和卡巴胂的單克隆抗體及酶聯免疫方法與試劑盒。ZL201210176485.0。序3
21. 用於檢測3-甲基喹噁啉-2-羧酸的單克隆抗體及酶聯免疫方法與試劑盒。ZL201210045175.5。序3
22. 用於檢測磺胺類藥物的單克隆抗體及酶聯免疫方法與試劑盒。ZL201210045195.2。序3
23. 檢測孔雀石綠、無色孔雀石綠、無色結晶紫的單抗及酶聯免疫方法與試劑盒。ZL201210045217.5。序3
24. 泰樂菌素和替米考星殘留檢測用單克隆抗體及酶聯免疫方法與試劑盒。ZL200710052663.8。序3
25. 喹噁啉-2-羧酸殘留的酶聯免疫檢測方法及試劑盒。ZL200610064837.5。序3
26. 用於檢測苯乙醇胺A的單克隆抗體及酶聯免疫方法與試劑盒。ZL201410830040.9。序4
27. 一種3-甲基喹噁啉-2 羧酸免疫親和柱及其製備方法。ZL201510018577.X。序4
28. 用於檢測ß-受體興奮劑的單克隆抗體及酶聯免疫方法與試劑盒。ZL201210176538.9。序4
29. 用於檢測萊克多巴胺的單克隆抗體及酶聯免疫方法與試劑盒。ZL201210176468.7。序4
30. 用於檢測慶大黴素和西索黴素的單克隆抗體及酶聯免疫方法與試劑盒。ZL201210045205.2。序4
31. 用於檢測β-胡蘿蔔素類色素的單克隆抗體及酶聯免疫方法與試劑盒。ZL201210045212.2。
32. 用於檢測新黴素、阿米卡星和巴龍黴素的單抗和酶聯免疫方法與試劑盒。ZL201210045202.9。序4
33. 基於螢光素酶標記工程菌的氟喹諾酮類藥物殘留檢測方法。ZL201310578673.0。序5
34. 3-甲基喹噁啉-2-羧酸殘留的酶聯免疫檢測方法及試劑盒。ZL200610164836.0。序5.

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