基本介紹
- 中文名:張奇亞
- 國籍:中國
- 民族:漢
- 職業:教師
- 職稱:研究員
- 學歷:研究生
個人簡歷,研究方向,研究課題,專家類別,獲獎及榮譽,代表論著,中英文雙語論著,主編研究生教材,參編英文專著,部分論文題錄,
個人簡歷
張奇亞, 武漢大學理學學士,美國俄亥俄醫學院 (Medical College of Ohio, MCO) 醫學碩士,中國科學院水生生物研究所理學博士。先後在中國科學院武漢病毒研究所、美國俄亥俄醫學院、美國加州大學聖迭戈分校 (University of California,San Diego, UCSD) 和中國科學院水生生物研究所從事病毒學及分子生物學相關領域的研究工作。兼國際病毒分類委員會委員,湖北省電鏡學會副理事長和省微生物學會理事。已發表論文200餘篇,其中SCI論文100餘篇;主著(編)論著2部,參編論著10餘部。獲國家授權發明專利6項,獲湖北省自然科學二等2項獎、中國科學院教學成果二等獎、中國科學院優秀研究生導師獎和中國科學院朱李月華優秀教師獎。培養博士後4名,畢業研究生34名 (含博士22名),其中2篇學位博士論文入選“湖北省優博論文”,5人次獲“研究生國家獎”;多數研究生獲其他冠名獎、三好學生獎、優秀畢業生獎等。
研究方向
研究課題
主持的學科組長期從事水生病毒及其分子生物學研究。結合現代生物技術與病毒學方法,運用和/或創建水生病毒重組、多組學與高通量篩選、螢光顯微與電子顯微、分子免疫及病毒入侵示蹤等技術,對水生病毒的病原生物學及分子特性進行研究。
專家類別
享受政府特殊津貼
獲獎及榮譽
湖北省自然科學二等獎(2004)
中國科學院教學成果二等獎(2008)
獲中國科學院朱李月華優秀教師獎(2009)
湖北省優秀博士學位論文指導教師獎(2009, 2012)
代表論著
中英文雙語論著
Zhang QY, Gui JF. 2012. Atlas of Aquatic Viruses and Viral Diseases. Science Press, Beijing, pp1-479 [張奇亞 桂建芳 著. 2012. 《水生病毒與病毒病圖鑑》. 科學出版社, 北京, 1-479頁]
主編研究生教材
張奇亞, 桂建芳 編著. 2008.《水生病毒學》(研究生教材), 高等教育出版社, 北京, 1-414頁
參編英文專著
Gray MJ,Chinchar VG (eds). 2015. Ranaviruses Lethal Pathogens of Ectothermic Vertebrates. Springer. Pp 105-139
Gui JF, Tang QS, Li ZJ, Liu JS, Silva SSDe (eds). 2018. Chinese Aqaculture: Succes Stories and Modern Trends. Chichester, UK: Wiley UK. Pp 577-598
部分論文題錄
Ke F, He LB, Zhang QY, 2013. Nonstructural protein NS80 is crucial in recruiting viral components to form aquareoviral factories. PLoS One
Zhu R, Wang J, Lei XY, Gui JF, Zhang QY. 2013. Evidence for Paralichthys olivaceus IFITM1 antiviral effect by impeding viral entry into target cells. Fish & Shellfish Immunology, (accepted)
Zhu RL, Zhang QY. 2013. Determination and analysis of the complete genome sequence of Paralichthys olivaceus rhabdovirus (PORV). Arch Virology, (accepted)
PeiC, Lei XY, Yuan XP, Wang D, Zhao QZ, Zhang QY. 2012. Herpes-like Virus Infection in Yangtze Finless Porpoise (Neophocaena phocaenoides): Pathology, Ultrastructure and Molecular Analysis. Journal of Wildlife Diseases,
He LB, Ke F, Zhang QY. 2012. Rana grylio virus as a vector for foreign gene expression in fish cell. Virus Research
Chen ZY, Lei XY, Zhang QY, 2012.The antiviral defense mechanisms in mandarin fish induced by DNA vaccine against a rhabdovirus. Veterinary Microbiology
Lei XY, Chen ZY, He LB, Pei C, Yuan XP, Zhang QY. 2012. Characterization and virus susceptibility of a skin cell line from red-spotted grouper (Epinephelus akaara). Fish Physiol Biochem
Li S, Sun F, Zhang YB, Gui JF, Zhang QY. 2012. Identification of Zebrafish Gig2 as a Noel Antiviral Factor Regulated by RLR Signaling Pathway. PLoS One
Lei XY, Ou T, Zhu RL, Zhang. QY. 2012. Sequencing and analysis of the complete genome of Rana grylio virus (RGV). Arch Virol
Lei XY, Tong Ou, Qi-Ya Zhang. Rana grylio virus (RGV) 50L is associated with viral matrix and exhibited two distribution patterns. PLoS One
Gao EB, Gui JF, Zhang QY. 2012. A Novel Cyanophage with Cyanobacterial Non-bleaching Protein A Gene in the Genome. Journal of Virology
Ke F, He LB, Pei C, Zhang QY. 2011. Turbot reovirus (SMReV) genome encoding a FAST protein with a non-AUG start site. BMC Genomics,
Zhu RL, Lei XY, Ke F, Yuan XP, Zhang QY. 2011. Genome of turbot rhabdovirus exhibits unusual non-coding regions and a novel additional ORF that could be expressed in fish cell. Virus Research
Kim YS, Ke F, Lei XY, Zhu R, Zhang QY, 2010 Viral envelope protein 53R gene highly specific silencing and iridovirus resistance in fish cells by amiRNA. PLoS One
Kim YS, Ke F, Zhang QY, 2009. Effect of β-glucan on activity of antioxidant enzymes and Mx gene expression in virus infected grass carp. Fish & Shellfish Immunology
Gao EB, Yuan XP, Li RH, Zhang QY, 2009. Isolation of a novel cyanophage infectious to filamentous cyanobacterium Planktothrix agardhii (cyanophyceae) from Lake Donghu in China. Aquatic Microbial Ecology
Zhao Z, Ke F, Shi Y, Zhou GZ, Gui JF, Zhang QY, 2009. Rana grylio virus thymidine kinase gene: an arly gene of iridovirus encoding for the cytoplasmic protein. Virus Gen
Ke F, Zhao Z, Zhang QY. 2009. Cloning, expression and subcellular distribution of a Rana grylio virus late gene encoding ERV1 homologue. Molecular Biology Reports
Zhu R, Zhang YB, Zhang QY, Gui JF, 2008. Functional domains and the antiviral effect of the dsRNA-dependent protein kinase PKR from Paralichthys olivaceus. Journal of Virology
Zhao Z, Shi Y, Ke F, Wei W, Gui JF, Zhang QY, 2008. Constitutive expression of thymidylate synthase from LCDV-C induces foci formation and anchorage-independent growth in fish cells. Virology
Zhao Z, Ke F, Huang YH, Zhao JG, Gui JF, Zhang QY. 2008. Identification and characterization of a novel envelope protein in Rana grylio virus. Journal General Virology
Tao JJ, Zhou GZ, Gui JF, Zhang QY, 2008. Genomic sequence of mandarin fish rhabdovirus with an unusual small non-transcriptional ORF. Virus Research
Zhou GZ, Gui L, Li ZQ, Yuan XP, Zhang QY, 2008. Generation and characterization of monoclonal antibodies against the flounder Paralichthys olivaceus rhabdovirus. Journal of virological Methods
Zhao Z, Ke F, Li ZQ, Gui JF, Zhang QY, 2008.Isolation, characterization and genome sequence of a birnavirus strain from flounder Paralichthys olivaceus in China. Archives Virology
Chen ZY, Liu H, Li ZQ, Zhang QY, 2008. Development and characterization of monoclonal antibodies to spring viraemia of carp virus. Veterinary Immunology and Immunopathology
Lü AJ, Li ZQ, Zhang QY, 2008. Detection of cutaneous antibodies in excised skin explants from Grass carp, Ctenopharyngodon idellus, immune to Scophthalmus maximus rhabdovirus. Journal of Fish Diseases,
Huang YH, Huang XH, Gui JF, Zhang QY, 2007.Mitochondria-mediated apoptosis induced by Raa glylio virus infection in fish cells. Apoptosis
Zhao Z, Ke F, Gui JF, Zhang QY, 2007. Characterization of an early gene encoding for dUTPase from Rana grylio virus. Virus Research
Tao JJ, Zhang QY, Gui JF, 2007. Isolation and characterization of a rhabdovirus from coinfection of two viruses in mandarin fish. Aquaculture
Huang YH, Huang XH, Zhang J, Gui JF, Zhang QY, 2007. Subcellular localization and characterization of G protein-coupled receptor homolog from lymphocysis disease virus isolated in China. Viral Immunology
Zhou GZ, Li ZQ, Zhang QY, 2007. Establishment, characterization and virus susceptibility of a new marine cell line from red spotted grouper (Epinephelus akaara). Marine Biotechnology
Zhang QY, Tao JJ, Gui L, Zhou GZ, Ruan HM, Li ZQ, Gui JF, 2007. Isolation and characterization of Scophthalmus maximus (turbot) rhabdovirus. Diseases of Aquatic Organisms
Huang XH, Zhang QY, 2007. Improvement and observation of immunoelectron microscopic method for the localization of frog Rana grylio virus (RGV) in infected fish cells. Micro
Lü AJ, Dong CW, Du CS, Zhang QY, 2007. Characterization and inductive expression of flounder voltage-dependent anion channel gene (VDAC) in response to virus infection. Fish & Shellfish Immunology
Huang XH, Huang YH, Yuan XP, Zhang QY, 2006. Electron microscopic Analysis of the Viromatrix of Rana grylio Virus in a Fish Cell line. Journal of Virological Methods
Zhang QY, Zhao Z, Xiao F, Li ZQ, Gui JF, 2006. Molecular characterization of three Rana grylio virus (RGV) isolates and Paralichthys olivaceus lymphocystis disease virus (LCDV-C) in iridoviruses. Aquaculture,
Liu YM, Zhang QY, Yuan XP, Li ZQ, Gui JF, 2006. Seasonal variation of virioplankton in a eutrophic shallow lake. Hydrobiologia
Zhu R, Zhang YB, Chen YD, Dong CW, Zhang FT, Zhang QY, Gui JF, 2006. Molecular cloning and stress-induced expression of paralichthys olivaceus heme-regulated initiation factor 2a kinase. Developmental & Comparative Immunology
Liu YM, Yuan XP, Zhang QY, 2006. Spatial distribution and morphologic diversity of virioplankton in Lake Donghu, China. Acta Oecologica-International Journal of Ecology
Sun W, Huang YH, Zhao Z, Gui JF, Zhang QY, 2006. Characterization of the Rana grylio virus 3β-hydroxysteroid dehydrogenase and its novel role in suppressing virus-induced cytopathic effect. Biochemical & Biophysical Research Communications
Zhou GZ, Li ZQ, Zhang QY, 2006. Characterization and application of monoclonal antibodies against the turbot (Scophthalmus Maximus) rhabdovirus (SMRV). Viral Immunology
Zhang QY, Xiao F, Xie J, Li, ZQ Gui JF. 2004. Complete genome sequence of lymphocystis disease virus (LCDV-C) isolated from China. Journal of Virology