基本介紹
- 中文名：張全啟
- 國籍：中國
- 職業：中國海洋大學教授
- 研究領域：海洋生物基因組學、遺傳學
學習與工作經歷,主要研究領域,主要研究課題,主要代表作,
學習與工作經歷
1979-1983：中國海洋大學（原山東海洋學院）海洋生命學院，獲理學學士學位。
1983-1986：中國海洋大學海洋生命學院，獲理學碩士學位。
1986-1994：中國海洋大學海洋生命學院，助教、講師。
1994.10-1998.2：日本廣島大學生物生產學部，獲哲學博士學位。
1998.3-1999.2：美國威廉馬麗大學海洋研究所，博士後。
1999.3-2001.2：日本水產養殖研究所科技廳特別研究員（博士後）。
1999.12—現在：中國海洋大學海洋生命學院教授、博士生導師。其中，
2003.10-2011.7期間，任中國海洋大學海洋生命學院院長。
主要研究領域
一直從事海洋生物遺傳學和基因組學研究，主要研究內容包括：
（1）魚類分子和遺傳學及優良品種選育；
（2）魚類染色體組操作與性別決定機制；
（3）魚類基因組學和功能基因研究；
（4）魚類胚胎幹細胞、生殖幹細胞分離培養、移植記借腹生子研究。
主要研究課題
1. 鮃鰈類高產、抗逆品種選育，國家“十一五”“863”課題，185萬。2006-2010。副主持。
2.名貴海水魚類苗種繁育，國家“十一五”“863”課題，60萬。2006-2010。參加。
3.利用種間雜交構建牙鮃和石鰈遺傳連鎖圖譜，國家自然科學基金，28萬，2007-2009。主持。
4. 優質抗病速生魚類良種選育，山東省農業良種工程重大課題，360萬，2006-連續支持。首席。
5. 鮃鰈魚類原始生殖細胞和精原細胞識別的分子基礎及其分離鑑定，國家自然科學基金，58萬，2010-2014。主持。
6. 泰山學者團隊建設經費，山東省委組織部人才建設項目，25萬，2010-2015。
7. 海洋動物細胞分子育種關鍵技術，國家“十二五”“863”課題，320萬。2012-2015。主持。
8. 重要鮃鰈魚類良種培育，國家“十二五”“863”課題，115萬。2012-2015。子課題。
主要代表作
1. Dongyi Yu, Quanqi Zhang*, Zhigang Wang, Jie Qi, Xinglian Wang. 2008. Characterization on the alternative splicing, expression and gene phylogenesis of PTPR4 family in Japanese flounder,Paralichthys olivaceus. Genes and Genetic Systems 83(2), 189-197.
2. Qiwang Zhong, Quanqi Zhang*, Yanjie Chena, Yeying Suna, Jie Qia, Zhigang Wanga, Shuo Lia, Chunmei Liaand Xun Lan. 2008. The isolation and characterization of myostatin gene in Japanese flounder (Paralichthys olivaceus): Ubiquitous tissue expression and developmental specific regulation. Aquaculture, 281 (1-4): 247-255.
3. Qiwang Zhong, Quanqi Zhang*, Zhigang Wang, Jie Qi, Yanjie Chen, Shuo Li, Yeying Sun, Chunmei Li, Xun Lan, 2008. Expression Profiling and Validation of Potential Reference Genes During Paralichthys olivaceusEmbryogenesis. Marine Biotechnology. 10(3): 310-318.
4. Xubo Wang, Quanqi Zhang*, Xiaohua Sun, Guoliang Yin, Jie Qi, Zhigang Wang And Xinglian Wang. 2008. Isolation and characterization of 64 novel microsatellite markers from a fosmid library of female half-smooth tongue sole (Cynoglossus semilaevis). Molecular Ecological Resources 2008(8): 1303-1306.
5. Xu xiaofei1, Zhang Quanqi*, Wang Zhigang，Qi Jie, Zhang Zhifeng, Bao Zhenming and Heisuke Nakagawa, 2006. Assessing genetic diversity of wild populations of Japanese flounder using AFLP markers, Acta Oceanologica Sinica.25(3): 82-89.
6. Xubo Wang, Quanqi Zhang*, Xiaohua Sun, Yanjie Chen, Teng Zhai, Wei Zhuang, Jie Qi and Zhigang Wang. 2009. Fosmid Library Construction and Initial Analysis of End Sequences in Female Half-smooth Tongue Sole (Cynoglossus semilaevis) Marine Biotechnology, 11(2): 236-242.
7.Yan Yu, Qiwang Zhong, Chunmei Li, Liming Jiang; Fusheng Yan; Zhigang Wang; Quanqi Zhang*, 2009. Isolation and characterization of Toll-like receptor 9 in half-smooth tongue sole Cynoglossus semilaevis. Fish and Shellfish Immunology. 26：492-499.
8.ZHANG Quanqi*, SUN Xiaohua, QI Jie, WANG Zhigang, WANG Xinglian, WANG Xubo, and ZHAI Teng. 2009. Sex Determination Mechanisms in Fish. J. Ocean Univ. China，8 (2): 155-160.
9. Chen Yanjie, Zhang Quanqi*, Qi Jie, Sun Yeying, Zhong Qiwang, Wang Xubo, Wang Zhigang, Li Shuo, Li Chunmei. 2009. Screening of eye-position related genes with DD-RT and RDA in the hybrids between Japanese flounder (Paralichthys olivaceus) and stone flounder (Kareius bicoloratus). Chinese Journal of Oceanology and Limmnology, 27(1): 92-99. (SCI)
10. Jianpeng Xu, Quanqi Zhang*, Xiaofei Xu, Zhigang Wang, Jie Qi. 2009. Intragenomic Variability and Pseudogenes of Ribosomal DNA in Stone Flounder Kareius bicoloratus. Molecular Phylogenetics and Evolution 52 (2009) 157-166.
11. Yan Yu, Qiwang Zhong, Chunmei Li, Liming Jiang; Fusheng Yan; Zhigang Wang; Quanqi Zhang*, 2009. Full-length sequence and expression analysis of a myeloid differentiation factor 88 (MyD88) in half-smooth tongue sole Cynoglossus semilaevis. International Journal of Immunogenetics. 36: 173–182.
12. Qiwang Zhong, Yan Yu, Quanqi Zhang*, Zhigang Wang, Haiyang Yu. 2009. Isolation and characterization of twenty novel microsatellite markers for half-smooth tongue sole (Cynoglossus semilaevis), Conservation Genetics. 10: 1617–1620.
13. Xubo Wang, Quanqi Zhang*, Jian Ren, Zhanjun Jiang, Changmeng Wang, Wei Zhuang, Teng Zhai, 2009. The preparation of sex-chromosome-specific painting probes and construction of sex chromosome DNA library in half-smooth tongue sole (Cynoglossussemilaevis). Aquaculture, 297: 78-84. AQUA-
14. WANG Xubo, ZHANG Quanqi*, CHEN Yanjie, QI Jie, WANG Zhigang, WANG Xinglian, 2009. Cytogenetic characterization of olive flounder Paralichthys olivaceus: DNA content, karyotype, AgNORs and location of major ribosomal genes. Acta Oceanologica Sinica, 28(4): 72-77.
15. Yeying Sun, Haiyang Yu, Quanqi Zhang*, Jie Qi, Qiwang Zhong, Yanjie Chen, Chunmei Li. 2010. Molecular characterization and expression pattern of two zona pellucida genes in half-smooth tongue sole (Cynoglossus semilaevis). Comparative Biochemistry and Physiology, Part B. 155 (2010) 316–321.
16. Shuo Li, Chunmei Li, Xubo Wang, Yanan Wang, Zhipeng Liu, Teng Zhai and Quanqi Zhang*. 2010. Molecular cloning and expression of PoIR2, a novel gene involved in immune response in Japanese flounder (Paralichthys olivaceus). Journal of Ocean University of China (English Edition), 9(1): 59-64.
17. Yeying Sun, Quanqi Zhang*, Jie Qi, Yanjie Chen, Qiwang Zhong, Yan Yu, Shuo Li, Zhigang Wang, Chunmei Li. 2010. Identification of differential genes in the ovary relative to the testis and their expression patterns in half-smooth tongue sole (Cynoglossus semilaevis). J. Genet. Genomomics, 37 (2): 137-145.
18. CHEN Yanjie, ZHANG Quanqi*, QI Jie, WANG Zhigang, WANG Xubo, SUN Yeying, ZHONG Qiwang, LI Shuo, LI Chunmei. 2010. Cloning and stage-specific expression of CK-M1 gene during metamorphosis of Japanese flounder, Paralichthys olivaceus. Chinese Journal of Oceanology and Limmnology, 28(3): 558-564.
19.Yuding Fan, Shuo Li, Jie Qi, Lingbing Zeng, Qiwang Zhong, Quanqi Zhang*. 2010. Cloning and characterization of type II Interleukin-1 receptor cDNA from Japanese flounder (Paralichthys olivaceus). Comparative Biochemistry and Physiology, Part B. 157: 59–65.
20. Jiashi Wang, Haiyang Yu, Hui Huang, Zhongjia Huang, Xubo Wang, Zhigang Wang & Quanqi Zhang*. 2009. Isolation and characterization of 21 novel microsatellite markers from spotted halibut (Verasper variegatus). Aquaculture Research，2010, 41, 930-933.
21.Quanqi Zhang*, Haiyang Yu, Aimee Howe, Whitney Chandler & Standish K. Allen Jr. 2010. Cytogenetic mechanism for reversion of triploids to heteroploid mosaics in Crassostrea gigas (Thunberg) and Crassostrea ariakensis. Aquaculture Research, 41, 1658-1667.
22. Quanqi Zhang*, Yan Zhuang and Standish K. Allen. 2010. Meiotic chromosome configurations in triploid and heteroploid mosaic males of Crassostrea gigas andCrassostrea. ariakensis. Aquaculture Research, 41, 1699-1706.
23. Li, C., Yu, Y., Sun, Y., Li, S., Zhong, Q., Wang, X., Wang, Z., Qi, J., Zhang, Q*. 2010. Isolation, polymorphism and expression study of two distinct major histocompatibility complex class II B genes from half-smooth tongue sole (Cynoglossus semilaevis). Intern. J. Immunogenet. 37(3):185-197.
24.Zhang J. Y., Wang W. J., Meng X. H., Kong J., Wang Q. Y., and Zhang Q. Q*. 2011. Genotyping of Single Nucleotide Polymorphisms in Fenneropenaeus chinensis (Decapoda, Penaeidae) by Tetra-Primer ARMA-PCR. Russian Journal of Marine Biology. 401-408.
25. Chunmei Li, Quanqi Zhang*, Yan Yu, Shuo Li, Qiwang Zhong, Yeying Sun, Zhigang Wang, Jie Qi, Jieming Zhaiand Xubo Wang. 2011. Sequence polymorphism of two major histocompatibility (MH) class II B genes and their association with Vibrio anguillarum infection in half-smooth tongue sole (Cynoglossus semilaevis). Chinese Journal of Oceanology and Limnology, 29 (6): 1275-1286.
26. LI Chunmei, WANG Xubo, ZHANG Quanqi*, WANG Zhigang, QI Jie, YI Qilin, LIU Zhipeng, WANG Yanan, and YU Haiyang. 2012. Identification of two Major Histocompatibility (MH) Class II A Genes and Their Association to Vibrio anguillarum Infection in Half-smooth Tongue Sole (Cynoglossus semilaevis). J. Ocean Univ. China 2011 10 (4): 106-112.
27. Yan Yu, Qiwang Zhong, Chunmei Li, Liming Jiang, Yanan Wang, Yeying Sun, Xubo Wang, Zhigang Wang, Quanqi Zhang*. 2012. Identification and characterization of IL-1 receptor-associated kinase-4 (IRAK-4) in half-smooth tongue sole Cynoglossus semilaevis. Fish and Shellfish Immunology. 32(4):609-15.
28. Yu Y, Zhong QQ, Li CM, Jiang LM, Sun YY, Wang XB, et al. Molecular cloning and characterization of Interleukin-1β in half-smooth tongue sole Cynoglossus semilaevis. Veterinary Immunology and Immunopathology. In press.
29. 房新英, 張全啟*, 齊潔, 包振民，2006，野生和養殖牙鮃(Paralichthys olivaceus)遺傳差異的RAPD和ISSR研究。海洋與湖沼， 37（2）：138-142。
30. 李君竹, 張全啟*, 齊潔，王興蓮，王志剛，2006，牙鮃（♀）×星鰈（♂）雜交子代的胚胎及仔魚發育。中國水產科學， 13（5）:732-736。
31. 王旭波，張全啟*，齊潔，王志剛，王興蓮, 2008. 牙鮃鰓細胞系染色體組型的變異分析。中國水產科學15（3）：483-487。
32. 孫業盈，張全啟*，齊潔，王志剛，陳妍婕，李春梅，鐘其旺，2008. 半滑舌鰨DMRT1基因的克隆與表達分析, 武漢大學學報(理學版) ，Vol. 54，No. 2 ：221～226。
33. 孫業盈，張全啟*，齊潔，陳妍婕，李春梅，鐘琪旺，王志剛，2008. 半滑舌鰨的一種細胞凋亡抑制因子的克隆、鑑定與分析。中國海洋大學學報，38（6）：927-931。
34. 徐建鵬，張全啟，王志剛，齊潔，王旭波. 2009. ISSR 標記在牙鮃(Paralichthys olivaceus)與石鰈(Kareius bicoloratus)種間雜交一代的分離方式分析。海洋與湖沼，40（5）：1-5。
35. 徐建鵬，張全啟*，王志剛，齊潔，王旭波. 2009。石鰈野生群體和養殖群體遺傳多樣性的ISSR分析。海洋學報31（4）：128-134。
36. 李朔，齊潔，王志剛，范玉頂，李春梅，劉志鵬，張全啟*. 2009. 牙鮃Fibrinogen β基因的克隆及表達分析。中山大學學報，48(6)：89-94。
37. 莊岩，藍勛，王志剛，王旭波，齊潔，張全啟*. 2010. 牙鮃同質雌核發育二倍體的誘導及其早期生長研究。中國海洋大學學報，40(6): 96-102.
38. 楊俊傑，張全啟*，劉保忠，劉坤. 2010. 鰈形目分類信息分析系統的建立與實現。中國海洋大學學報，40 (7): 59-65.
39. 嚴福升，王志剛，劉旭東，劉志鵬，張全啟*. 2010. 3月齡牙鮃形態性狀對體質量的通徑分析。漁業科學進展，31（2）：45-50。
40. 范玉頂，陳妍婕，鐘其旺，齊潔，張全啟*. 2010. 利用DD-PCR分離鰻弧菌刺激相關的牙鮃差異cDNA。中國水產科學，17(3)：431-438。
41. 孫曉華，張全啟*，王旭波，翟騰，齊潔，王志剛，王興蓮，王亞楠.2009. 半滑舌鰨雌魚 Fosmid 基因組文庫的構建及分析。中國海洋大學學報，40（8）：88-97.
42.姜黎明, 于海洋, 張全啟*, 劉志鵬, 劉俊偉, 王旭波, 王志剛, 翟介明. 2011. 半滑舌鰨微衛星標記的開發及其在F1家系中分離方式分析。中國水產科學，18（6）：1384-1391。
43. 翟騰，王旭波，王晶，高金寧，翟介明，張全啟*. 2011. 半滑舌鰨雌性特異fosmid克隆的篩選及FISH定位, 中國海洋大學學報，41 (11): 57-60。
