尹文兵，男，畢業於山西師範大學，博導，中國科學院微生物研究所研究員。
基本介紹
人物經歷,主要成就,
人物經歷
2014-01--今 中國科學院微生物研究所 研究員
2012-11--2014-01 美國加州大學洛杉磯分校 博士後
2009-10--2012-10 美國威斯康辛大學麥迪遜分校 研究助理
主要成就
發表論文
（1） Duplication of a Pks gene cluster and subsequent functional diversification facilitate environmental adaptation in Metarhizium species, PloS Genet., 2018, 第 8 作者
（2） Deletion of a global regulator LaeB leads to the discovery of novel polyketides in Aspergillus nidulans, Org. Biomol. Chem., 2018, 通訊作者
（3） A new regulator RsdA mediating fungal secondary metabolism has a detrimental impact on asexual development in Pestalotiopsis fici, Environ. Microbiol., 2018, 通訊作者
（4） Rational design for heterologous production of aurovertin-type compounds in Aspergillus nidulans, Appl. Microbiol. Biotechnol., 2018, 通訊作者
（5） Asperorydines A–M: prenylated tryptophan-derived alkaloids with neurotrophic effects from Aspergillus oryzae, J Org Chem, 2018, 第 8 作者
（6） Asperphenamate biosynthesis reveals a novel two-module NRPS system to synthesize amino acid esters in fungi, Chem. Sci, 2018, 通訊作者
（7） Identification and characterization of a membrane-bound sesterterpene cyclase from Streptomyces somaliensis., J. Nat. Prod, 2018, 第 8 作者
（8） Trichodermatides E and F from fungus Trichoderma applanatum, J. Asian Nat. Prod. Res., 2018, 通訊作者
（9） Rational design for fungal laccase production in the model host Aspergillus nidulans, SCIENCE CHINA Life Sciences, 2018, 通訊作者
（10） Synthesis and production of the antitumor polyketide aurovertins and structurally related compounds, Appl. Microbiol. Biotechnol., 2018, 通訊作者
（11） Genetic manipulation of the COP9 signalosome subunit PfCsnE leads to the discovery of pestaloficins in Pestalotiopsis fici, Org Lett., 2017, 通訊作者
（12） Decalin-containing tetramic acids and 4-hydroxy-2-pyridones with antimicrobial and cytotoxic activity from the fungus coniochaeta cephalothecoides collected in Tibetan Plateau (Medog), J Org Chem, 2017, 第 10 作者
（13） Versicoamides F–H, prenylated indole alkaloids from Aspergillus tennesseensis, Org Lett., 2017, 第 9 作者
（14） Mutation on Gly115 and Tyr205 of the cyclic dipeptide C2-prenyltransferase FtmPT1 increases its catalytic activity toward hydroxynaphthalenes, Appl. Microbiol. Biotechnol., 2017, 第 5 作者
（15） Regio- and stereospecific O-glycosylation of phenolic compounds catalysed by a fungal glycosyltransferase from Mucor hiemalis, Adv. Synth. Catal., 2017, 通訊作者
（16） Deletion of a histone acetyltransferase leads to the pleiotropic activation of natural products in Metarhizium robertsii, Org. Lett., 2017, 通訊作者
（17） Discovery and characterization of the UbiA proteins as a new family of diterpene cyclases in bacteria and fungi, Angew. Chem. Int. Ed., 2017, 第 10 作者
（18） Chemical diversity from the Tibetan Plateau fungi Penicillium kongii and P. brasilianum, Mycology (TMYC), 2017, 第 8 作者
（19） A cryptic pigment biosynthetic pathway uncovered by heterologous expression is essential for conidial development in Pestalotiopsis fici, Mol. Microbiol., 2017, 通訊作者
（20） COP9 signalosome subunit PfCsnE regulates secondary metabolism and conidial formation in Pestalotiopsis fici, SCIENCE CHINA Life Sciences, 2017, 通訊作者
（21） Bioactive Spirobisnaphthalenes and Lactones from a Cup Fungus Plectania sp Collected in the Tibet Plateau Region, Eur. J. Org. Chem., 2016, 第 7 作者
（22） Bioactive sesquiterpenes from the edible mushroom flammulina velutipes and their biosynthetic pathway confirmed by genome analysis and chemical evidence, J. Org. Chem., 2016, 第 10 作者
（23） Functional analysis of the nitrogen metabolite repression regulator gene nmrA in Aspergillus flavus, Frontiers Microbiol., 2016, 第 4 作者
（24） A new species of Trichoderma hypoxylon harbours abundant secondary metabolites, Sci. Rep., 2016, 通訊作者
（25） Polyketide production of pestaloficiols and macrodiolide ficiolides revealed by manipulations of epigenetic regulators in an endophytic fungus., Org. Lett., 2016, 通訊作者
（26） Biosynthesis of Antibiotic Leucinostatins in Bio-control Fungus Purpureocillium lilacinum and Their Inhibition on Phytophthora Revealed by Genome Mining., PLoS Pathog, 2016, 通訊作者
（27） Efficient biosynthesis of fungal polyketides containing the dioxabicyclo-octane ring system., J. Am. Chem. Soc., 2015, 第 4 作者
（28） Lanostane triterpenes from the Tibetan medicinal mushroom Ganoderma leucocontextum and their inhibitory effects on HMG-CoA reductase and α-glucosidase., J. Nat. Prod., 2015, 第 4 作者
（29） Structurally diverse sesquiterpenes produced by a Chinese Tibet fungus Stereum hirsutum and their cytotoxic and immunosuppressant activities., Org. Lett., 2015, 第 4 作者
（30） Gloeophyllins A−J, cytotoxic ergosteroids with various skeletons from a Chinese Tibet fungus Gloeophyllum abietinum., Org. Lett., 2015, 第 4 作者
（31） From taxonomy and industry to genetics: Fungal Biology in China., Fungal Genet Biol., 2015, 通訊作者
（32） Epigenetic genome mining of an endophytic fungus leads to pleiotropic biosynthesis of natural products, Angew. Chem. Int. Ed., 2015, 第 4 作者
（33） The bZIP transcription factor PfZipA regulates secondary metabolism and oxidative stress response in the plant endophytic fungus Pestalotiopsis fici, Fungal Genet. Biol. , 2015, 通訊作者
（34） Genomic and transcriptomic analysis of the endophytic fungus Pestalotiopsis fici reveals its lifestyle and high potential for synthesis of natural products, BMC Genomics, 2015, 第 4 作者
（35） Farming of a defensive fungal mutualist by an attelabid weevil., ISME J., 2015, 第 4 作者
（36） A Carbonate-forming Baeyer-Villiger Monooxygenase., Nature Chem. Biol., 2014, 第 4 作者
（37） Perturbations in small molecule synthesis uncovers an iron-responsive secondary metabolite network in Aspergillus fumigatus., Front. Microbiol., 2014, 第 4 作者
（38） The bZIP protein MeaB mediates virulence attributes in Aspergillus flavus, PloS One, 2013, 第 3 作者
（39） Discovery of cryptic polyketide metabolites from dermatophytes using heterologous expression in Aspergillus nidulans, ACS Synth. Biol., 2013, 第 1 作者
（40） A nonribosomalpeptide synthetase-derived iron(III) complex from the pathogenic fungus Aspergillus fumigatus, J. Am. Chem. Soc., 2013, 第 1 作者
（41） bZIP transcription factors affecting secondary metabolism, sexual development and stress responses in Aspergillus nidulans, Microbiology-SGM, 2013, 第 1 作者
（42） An Aspergillus nidulansbZIP response pathway hardwired for defensive secondary metabolism operates through aflR, Mol. Microbiol., 2012, 第 1 作者
（43） Transcriptional regulatory elements in fungal secondary metabolism, J. Microbiol., 2011, 第 1 作者
（44） Preparation of pyrrolo[2,3-b]indoles carrying a ？-configured reverse C3-dimethylallyl moiety by using a recombinant prenyltransferase CdpC3PT, Org. Biomol. Chem., 2010, 第 1 作者
（45） Reconstruction of pyrrolo[2,3-b]indoles carrying an a-configured reverse C3-dimethylallyl moiety by using recombinant enzymes, Org. Biomol. Chem. , 2010, 第 1 作者
（46） Stereospecific synthesis of aszonalenins by using two prenyltransferases, Org. Biomol. Chem. , 2009, 第 1 作者
（47） Ergot alkaloid biosynthesis in Aspergillus fumigatus: FgaATcatalyses the acetylation of fumigaclavine B, ChemBioChem, 2009, 第 4 作者
（48） Acetylaszonalenin biosynthesis in Neosartorya fischeri: Identification of the biosynthetic gene cluster by genomic mining and functional proof of the genes by biochemical investigation, J. Biol. Chem., 2009, 第 1 作者
（49） Indole prenyltransferases from fungi: a new enzyme group with high potential for the production of prenylated indole derivatives, Curr. Med. Chem., 2009, 第 3 作者
（50） Reinvestigation of a cyclic dipeptide N-prenyltransferase reveals rearrangement of N-1 prenylated indole derivatives, Chembiochem, 2008, 第 1 作者
（51） CdpNPT, an N-prenyltransferase from Aspergillus fumigatus: overproduction, purification and biochemical characterisation, ChemBioChem , 2007, 第 1 作者
