主要以擬南芥和番茄為材料研究植物免疫信號傳導通路和抗病分子機制，闡明了植物中多個重要蛋白激酶介導植物免疫信號傳導及調控植物抗病性的機理機制。已發表論文近40篇，所發表論文已被引用3000多次。
2016年入選“國家海外高層次青年人才引進計畫”，2021年獲“衛志明青年創新獎”，主持多項國家自然科學基金項目。
擔任上海師範大學生命科學學院副院長、上海市植物分子科學重點實驗室主任。
基本介紹
- 中文名：孟祥宗
- 國籍：中國
- 畢業院校：聊城大學(學士)、上海大學(碩士)、中國科學院上海生命科學研究院植物生理生態研究所(博士)
- 職稱：教授
研究方向,教育經歷,工作經歷,科研項目,代表論文,通訊作者論文,第一作者論文,共同作者論文,
研究方向
[1]植物免疫信號傳導
[2]植物抗病分子機制
[3]植物抗病基因工程
教育經歷
2006-2010：博士，中國科學院上海生命科學研究院植物生理生態研究所
2003-2006：碩士，上海大學
1999-2003：學士，聊城大學
工作經歷
2019-至今：上海師範大學，教授
2016-2019：上海大學，教授
2013-2016：美國德州農工大學，博士後
2010-2013：美國密蘇里大學，博士後
科研項目
[1]國家海外高層次青年人才引進計畫，2016-2018
[2]國家自然科學基金面上項目（31671515），2017-2020
[3]國家自然科學基金面上項目（31970282），2020-2023
代表論文
通訊作者論文
（ corresponding author）
[1]Wang X., Zhang N., Zhang L., He Y., Cai C., Zhou J., Li J., and Meng X. 2021. Perception of the pathogen-induced peptide RGF7 by the receptor-like kinases RGI4 and RGI5 triggers innate immunity in Arabidopsis thaliana. New Phytologist 2021, 230(3): 1110-1125.
[2] Zhou J., Wang X., He Y., Sang T., Wang P., Dai S. Zhang S., and Meng X. Differential Phosphorylation of the Transcription Factor WRKY33 by the Protein Kinases CPK5/CPK6 and MPK3/MPK6 Cooperatively Regulates Camalexin Biosynthesis in Arabidopsis. Plant Cell 2020, 32(8): 2621-2638.
[3] He Y. and Meng X. MAPK signaling: emerging roles in lateral root formation. Trends in Plant Science 2020, 25(2): 126-129.
[4] He Y., Xu J., Wang X., He X., Wang Y., Zhou J., Zhang S., and Meng X. The Arabidopsis Pleiotropic Drug Resistance Transporters PEN3 and PDR12 Mediate Camalexin Secretion for Resistance to Botrytis cinerea. Plant Cell 2019, 31(9): 2206-2222.
[5]He Y., Zhou J., and Meng X. Phosphoregulation of Ca Influx in Plant Immunity. Trends in Plant Science 2019, 24(12): 1067-1069.
[6] He Y., Zhou J., Shan L., and Meng X. Plant cell surface receptor-mediated signaling: a common theme amid diversity. Journal of Cell Science 2018, 131(2): jcs209353.
第一作者論文
（* co-first author）
[1]Meng X., Zhou J., Tang J., Li B., de Oliveira M.V., Chai J., He P., and Shan L. Ligand-Induced Receptor-like Kinase Complex Regulates Floral Organ Abscission in Arabidopsis. Cell Reports 2016, 14(6): 1330-1338.
[2] Li B. *, Meng X.*, Shan L., and He P. Transcriptional Regulation of Pattern-Triggered Immunity in Plants. Cell Host & Microbe 2016, 19(5): 641-650.
[3]Meng X., Chen X., Mang H., Liu C., Yu X., Gao X., Torii K.U., He P., and Shan L. Differential function of Arabidopsis SERK family receptor-like kinases in stomatal patterning. Current Biology 2015, 25(18): 2361-2372.
[4]Meng X., Shan L., and He P. Stack Heterotrimeric G Proteins and MAPK Cascades on a RACK. Molecular Plant 2015, 8(12): 1691-1693.
[5]Meng X.*, Xu J.*, He Y., Yang K.-Y., Mordorski B., Liu Y., and Zhang S. Phosphorylation of an ERF Transcription Factor by Arabidopsis MPK3/MPK6 Regulates Plant Defense Gene Induction and Fungal Resistance. Plant Cell 2013, 25(3): 1126-1142.
[6]Meng X., and Zhang S. MAPK cascades in plant disease resistance signaling. Annual Review of Phytopathology 2013, 51: 245-266.
[7]Meng X., Wang H., He Y., Liu Y., Walker J.C., Torii K.U., and Zhang S. A MAPK cascade downstream of ERECTA receptor-like protein kinase regulates Arabidopsis inflorescence architecture by promoting localized cell proliferation. Plant Cell 2012, 24(12): 4948-4960.
[8] Li G.*, Meng X.*, Wang R.*, Mao G., Han L., Liu Y., and Zhang S. Dual-level regulation of ACC synthase activity by MPK3/MPK6 cascade and its downstream WRKY transcription factor during ethylene induction in Arabidopsis. PLoS Genetics 2012, 8(6): e1002767.
[9]Meng X., Xu Z., and Song R. Molecular cloning and characterization of a vacuolar H-pyrophosphatase from Dunaliella viridis. Molecular Biology Reports 2011, 38(5): 3375-3382.
[10]Meng X., Huang B., Zhou L., He Y., Chen Q., Yuan Y., Xu Z., and Song R. Construction of a Coix BAC library and isolation of the 22 kDa α-coixin gene cluster. Genome 2010, 53(9): 667-674.
[11] Sun X.*, Meng X.*, Xu Z., and Song R. Expression of the 26S proteasome subunit RPN10 is upregulated by salt stress in Dunaliella viridis. Journal of Plant Physiology 2010, 167(12): 1003-1008.
[12] He Y.*,Meng X.*, Fan Q., Sun X., Xu Z., and Song R. Cloning and characterization of two novel chloroplastic glycerol-3-phosphate dehydrogenases from Dunaliella viridis. Plant Molecular Biology 2009, 71(1-2): 193-205.
共同作者論文
[1] Xu G., Meng X., and Dou D. Differential Ubiquitination of BIK1 Fine-Tunes Plant Immunity. Trends in Plant Science 2021, 26(1): 2-4.
[2] Zhou J., Wang P., Claus L.A.N., Savatin D.V., Xu G., Wu S., Meng X., Russinova E., He P., and Shan L. Proteolytic processing of SERK3/BAK1 regulates plant immunity, development and cell death. Plant Physiology 2019, 180(1): 543-558.
[3] Zhou J., Liu D., Wang P., Ma X., Lin W., Chen S., Mishev K., Lu D., Kumar R., Vanhoutte I., Meng X., He P., Russinova E., and Shan L. Regulation of Arabidopsis brassinosteroid receptor BRI1 endocytosis and degradation by plant U-box PUB12/PUB13-mediated ubiquitination. Proc. Natl. Acad. Sci. U. S. A. 2018, 115(8): E1906-E1915.
[4] Fan J., Bai P., Ning Y., Wang J., Shi X., Xiong Y., Zhang K., He F., Zhang C., Wang R., Meng X., Zhou J., Wang M., Shirsekar G., Park C.H., Bellizzi M., Liu W., Jeon J.S., Xia Y., Shan L., and Wang G.L. The Monocot-Specific Receptor-like Kinase SDS2 Controls Cell Death and Immunity in Rice. Cell Host & Microbe 2018, 23(4): 498-510.
[5] Mang H., Feng B., Hu Z., Boisson-Dernier A., Franck C.M., Meng X., Huang Y., Zhou J., Xu G., Wang T., Shan L., and He P. Differential Regulation of Two-Tiered Plant Immunity and Sexual Reproduction by ANXUR Receptor-Like Kinases. Plant Cell 2017, 29(12): 3140-3156.
[6] Xu J., Meng J., Meng X., Zhao Y., Liu J., Sun T., Liu Y., Wang Q., and Zhang S. Pathogen-Responsive MPK3 and MPK6 Reprogram the Biosynthesis of Indole Glucosinolates and Their Derivatives in Arabidopsis Immunity. Plant Cell 2016, 28(5): 1144-1162.
[7] de Oliveira M.V., Xu G., Li B., de Souza Vespoli L., Meng X., Chen X., Yu X., de Souza S.A., Intorne A.C., de A Manhães A.M., Musinsky A.L., Koiwa H., de Souza Filho G.A., Shan L., and He P. Specific control of Arabidopsis BAK1/SERK4-regulated cell death by protein glycosylation. Nature Plants 2016, 2: 15218.
[8] Guan R., Su J., Meng X., Li S., Liu Y., Xu J., and Zhang S. Multilayered Regulation of Ethylene Induction Plays a Positive Role in Arabidopsis Resistance against Pseudomonas syringae. Plant Physiology 2015, 169(1): 299-312.
[9] Li F., Cheng C., Cui F., de Oliveira M.V., Yu X., Meng X., Intorne A.C., Babilonia K., Li M., Li B., Chen S., Ma X., Xiao S., Zheng Y., Fei Z., Metz R.P., Johnson C.D., Koiwa H., Sun W., Li Z., de Souza Filho G.A., Shan L., and He P. Modulation of RNA polymerase II phosphorylation downstream of pathogen perception orchestrates plant immunity. Cell Host & Microbe 2014, 16(6): 748-758.
[10] Guan Y., Meng X., Khanna R., LaMontagne E., Liu Y., and Zhang S. Phosphorylation of a WRKY transcription factor by MAPKs is required for pollen development and function in Arabidopsis. PLoS Genetics 2014, 10(5): e1004384.
[11] Mao, G., Meng, X., Liu, Y., Zheng, Z., Chen, Z., and Zhang, S. Phosphorylation of a WRKY transcription factor by two pathogen-responsive MAPKs drives phytoalexin biosynthesis in Arabidopsis. Plant Cell 2011, 23(4): 1639-1653.
